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The role of the pulmonary function test and the exercise test for assessing impairment/disability in patients with chronic airflow obstruction (심한 만성기류폐쇄 환자의 Impairment/Disability 측정에 있어 폐기능검사 및 운동부하검사의 역할)

  • Cheon, Seon-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.3
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    • pp.377-387
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    • 1996
  • Background : In 1980, WHO made a definition in which the term "impairment" as applied to the respiratory system is used to describe loss of lung function, "disability" the resulting diminution in exercise capacity. The measurement of pulmonary function during exercise would give us information about overall functional capacity and respiratory performance that would be lacking in tests performed at rest. We conducted this study to investigate the role of resting pulmonary function test and exercise test for assessing impairment/disability in patients with chronic airflow obstruction(CAO). Method : We studied 19 patients with CAO. The spirometry and body plethysmograph were performed in stable condition. And then patients performed a progressive incremental exercise test to a symptom-limited maximum using cycle ergometer. Patients were divided in two groups, severe and non-severe impairment, according to the resting PFTs and compaired each other. A patient was considered to be severely impaired if FVC < 50 %, FEV1 < 40 % or FEV1/FVC < 40 %. Results : 1) The airway obstruction and hypoxemia of severe impairment group were more severe and exercise performance was markedly reduced compairing to non-severe impairment group. 2) The severe impairment group showed ventilatory limitation during exercise test and the limiting symptomes ware dyspnea in 9/10 patients. 3) The impairment and disability of the patients with tuberculous destructed lung were most marked in patients with CAO. 4) The FEV1 was the most prevalent criterion for the determination of severe impairment based on resting PFTs and was the valuable best correlated to V02max(r=0.81, p < 0.001). 5) The sensitivity of exercise limits for predicting severe disability according to resting PFTs was 80 % and specificity 89 %. Conclusion : In patients with severe CAO, FEV1 is a good predictive of exercise performance and impairment measured by resting PFTs can predict a disability by exercise test.

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The Changes of Breathing Pattern Observed During Maximal Exercise Testing in the Patients with Chronic Airflow Obstruction : the Correlation Between the Change of Inspiratory Duty Cycle and the Degree of Airflow Obstruction (만성기도폐쇄 환자에서 최대운동부하시 관찰되는 호흡양상 - 기도폐쇄정도와 흡기책임비율변화 사이의 상관관계 -)

  • Lee, Kye-Young;Jee, Young-Koo;Kim, Keun-Youl
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.3
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    • pp.574-582
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    • 1997
  • Background : Normal humans meet the increased ventilatory need during exercise initially by the increase of tidal volume (TV) and later by the increase of respiratory frequency (Rf). And the inspiratory duty cycle (Ti/Ttot) is also increased more than 50% for the compensation of the decrease of respiratory cycle provoked by the increase of respiratory frequency. The patients with chronic airflow obstruction show rapid and shallow breathing pattern during exercise because of the decreased ventilatory capacity and the increased dead space ventilation. However, the studies about the change of inspiratory duty cycle are only a few and there is no literature about the relationship between the change of inspiratory duty cycle and the degree of airflow obstruction. Methods : The subjects were the twelve patients with chronic airflow obstruction (CAO) and ten normal people. The incremental exercise test was done. The increase of work load was 10 W in CAO group and 25 W in normal control group. The analysis of the results was done by the comparison of the parameters such as minute ventilation (VE), TV, Rf, physiologic dead space (Vd/Vt), and inspiratory duty cycle between the two groups. Each parameters were compared after transformation into % control duration base that means dividing the total exercise time into five fractions and % control duration data were obtained at rest, 20%, 40%, 60%, 80%, and max. Statistical analysis was done by repeated measure ANOVA using SAS program. Results : The changes of VE and TV were significantly different between two groups while the change of Rf was not significant. The decrease of Vd/Vt was significantly low in CAO group. Ti/Ttot was markedly increased from 38.4 + 3.0% at rest to 48.6 + 4.5% at max in normal control group while Ti/Ttot showed little change from 40.5 + 2.2% at rest to 42.6 + 3.5% at max. And the change of inspiratory duty cycle showed highly good correlation with the degree of airflow obstruction (FEV1%). (r=0.8151, p < 0.05). Conclusions : The increase of Ti/Ttot during exercise observed in normal humans is absent in the patients with CAO and the change of Ti/Ttot is well correlated with the degree of airflow obstruction.

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The completed SDSS-IV extended Baryon Oscillation Spectroscopic Survey: measurement of the BAO and growth rate of structure of the emission line galaxy sample from the anisotropic power spectrum between redshift 0.6 and 1.1

  • Arnaud de Mattia;Vanina Ruhlmann-Kleider;Anand Raichoor;Ashley J Ross;Amelie Tamone;Cheng Zhao;Shadab Alam;Santiago Avila;Etienne Burtin;Julian Bautista;Florian Beutler;Jonathan Brinkmann;Joel R Brownstein;Michael J Chapman;Chia-Hsun Chuang;Johan Comparat;Helion du Mas des Bourboux;Kyle S Dawson;Axel de la Macorra;Hector Gil-Marin;Violeta Gonzalez-Perez;Claudio Gorgoni;Jiamin Hou;Hui Kong;Sicheng Lin;Seshadri Nadathur;Jeffrey A Newman;Eva-Maria Mueller;Will J Percival;Mehdi Rezaie;Graziano Rossi;Donald P Schneider;Prabhakar Tiwari;M Vivek;Yuting Wang;Gong-Bo Zhao
    • Monthly Notices of the Royal Astronomical Society
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    • v.501 no.4
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    • pp.5616-5645
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    • 2021
  • We analyse the large-scale clustering in Fourier space of emission line galaxies (ELG) from the Data Release 16 of the Sloan Digital Sky Survey IV extended Baryon Oscillation Spectroscopic Survey. The ELG sample contains 173 736 galaxies covering 1170 deg2 in the redshift range 0.6 eff = 0.845 we measure DV(zeff)/rdrag = 18.33+0.57-0.62, with DV the volume-averaged distance and rdrag the comoving sound horizon at the drag epoch. In combination with the RSD measurement, at zeff = 0.85 we find fσ8(zeff) = 0.289+0.085-0.096, with f the growth rate of structure and σ8 the normalization of the linear power spectrum, DH(zeff)/rdrag = 20.0+2.4-2.2 and DM(zeff)/rdrag = 19.17 ± 0.99 with DH and DM the Hubble and comoving angular distances, respectively. These results are in agreement with those obtained in configuration space, thus allowing a consensus measurement of fσ8(zeff) = 0.315 ± 0.095, DH(zeff)/rdrag = 19.6+2.2-2.1 and DM(zeff)/rdrag = 19.5 ± 1.0. This measurement is consistent with a flat ΛCDM model with Planck parameters.

Magnetic Properties of Zn and La-Zn Substituted Strontium Ferrite (Zn 및 La-Zn 치환에 따른 Sr 페라이트의 자기적 특성에 관한 연구)

  • 장세동;김종오;김종희
    • Journal of the Korean Magnetics Society
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    • v.11 no.6
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    • pp.256-261
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    • 2001
  • These experiments were carried out to examine the effects of element substitution of Zn and La-Zn for Sr-ferrite. The calcined properties of Zn and La-Zn element substitution were examined, and also the sintered magnetic properties were compared with the stoichiometric condition. The magnetization properties of calcined SrM materials is as follows; M$\_$s/ : 61.06 emu/g. Also, the magnetization properties of calcined Zn$\_$0.3/-SrM materials is as follows; M$\_$s/ : 66.90 emu/g. The sintered magnetic properties of (La-Zn)$\_$0.3/-SrM composition is as follows; B$\_$r/ : 4.21 kG, BH$\_$max/: 4.19 MGOe.

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Dry Matter Distribution during Seedling Development in Soybean (콩의 유묘기간 중 건물중의 분배)

  • R. C. Seong;K. H. Choi;S. J. Park
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.4
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    • pp.416-423
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    • 1997
  • To obtain the basic information about the translocation of seed reserves of soybean[Glycine max(L.) Merrill] cultivars, 'Hill', 'Paldalkong' and 'Jangyeobkong' , the dry matter changes of emerging organs during the germination and seedling development were observed at the research farm of College of Natural Resources, Korea University, on May 26, June 5 and June 14. Mean fresh weight, dry weight and moisture content of three soybean cultivars were increased until the V2 stage in all seedling parts except cotyledons. Cotyledon dry weight was continuously decreased and the decreased amount at the V2 stage was about 80% of the cotyledon dry weight at the germination stage. Structural component of cotyledons was 22.2% of the cotyledon dry weight at the germination stage. Metabolic components of cotyledons were markedly decreased until V2 stage, and about 91% of cotyledon metabolic components at germination stage was utilized. However, those of whole seedling were increased after the V1 stage. Therefore, it appeared that role of cotyledons as nutrient supplier for germination and seedling growth was important until the V1 stage especially.

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The Development of Obesity Age (OA) for Health Index of Middle Aged Obese Women (중년기 비만여성에 있어서 건강지표를 위한 비만연령의 개발)

  • Lee, Dong-Jun;Park, Tae-Seop
    • Journal of Life Science
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    • v.19 no.10
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    • pp.1403-1409
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    • 2009
  • The purpose of this study was to compare Obesity Age (OA) and chronological age, to calculate Obesity Age (OA), which gauges the state of obesity, and to analyze presented factors of obesity using expectant factors on middle-aged obese women. The subjects were one hundred twenty seven middle-aged obese women ($49.6\pm7.3$ yr, BMI $29.41\pm2.9$, fat $36.8\pm4.6%$) who participated in different weight loss programs three times. The body composition, physical fitness, blood pressure and blood were measured before the weight loss programs. Informed consent was obtained from all subjects before enrollment in the study. The regression equation is as follows: (1) OAS (Obesity Age Score)=$0.106*X_1+0.035*X_2+0.048*X_3+0.041*X_4+0.003*X_5-0.037*X_6-10.667$ ($X_1$: BMI, $X_2$: weight, $X_3$: %fat, $X_4$: WC, $X_5$: TG, $X_6$: $VO_{2max}$), (2) OA (Obesity Age)=7.3*OAS+49.6*(-1), (3) Z (correction factor)=(CA-49.6)(1-0.03), (4) OAc (corrected Obesity Age)=1.03*CA-7.3*OAS+1.47. The comparison of corrected Obesity Age (OAc) and chronological age did not have any differences, and the average of the OAc was close to chronological age. The correlation coefficient between the OAc and chronological age was r=0.724 (p<0.05). The equation can be utilized for middle-aged obese women, because it could evaluate the obesity-related factors by including BMI, body weight, %fat, waist circumference, triglycerides and $VO_{2max}$.

Models of Pseudomonas Growth Kinetics and Shelf Life in Chilled Longissimus dorsi Muscles of Beef

  • Zhang, Yimin;Mao, Yanwei;Li, Ke;Dong, Pengcheng;Liang, Rongrong;Luo, Xin
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.5
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    • pp.713-722
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    • 2011
  • The aim of this study was to confirm Pseudomonas spp. as the specific spoilage organism (SSO) of chilled beef during aerobic storage and to establish a model to predict the shelf life of beef. Naturally contaminated beef was stored at $4^{\circ}C$, and the spoilage limit of Pseudomonas organisms was determined by measuring several quality indicators during storage, including the number of Pseudomonas organisms, total number of bacteria, total volatile basic nitrogen (TVBN) values, L value color scale scores and sensory evaluation scores. The beef was then stored at 0, 4, 7, 10, 15 or $20^{\circ}C$ for varying amounts of time, and the number of Pseudomonas organisms were counted, allowing a corresponding growth model to be established. The results showed that the presence of Pseudomonas spp. was significantly correlated to each quality characteristic (p<0.01), demonstrating that Pseudomonas spp. are the SSO of chilled beef and that the spoilage limit was $10^{8.20}$ cfu/g. The Baranyi and Roberts equation can predict the growth of Pseudomonas spp. in beef, and the $R^2$ value of each model was greater than 0.95. The square root model was used as follows, and the absolute values of the residuals were less than ${0.05:\;{\mu_{max}}^{1/2}$ = 0.15604 [T+(-0.08472)] (p<0.01), $R^2$ = 0.98, $\lambda^{-1/2}$ = 0.0649+0.0242T (p<0.01, $R^2$ = 0.94). The model presented here describes the impact of different temperatures on the growth of Pseudomonas spp., thereby establishing a model for the prediction of the shelf life of beef stored between 0 to $20^{\circ}C$.

Development Process of Mechanical Structure for a Large Radar (대형 레이더 기계구조부 개발 절차)

  • Shin, Dongjun;Lee, Jonghak;Kang, Youngsik
    • Journal of the Korea Institute of Military Science and Technology
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    • v.20 no.1
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    • pp.1-11
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    • 2017
  • In this paper, design requirements of the large radar were investigated, and development was performed through the analysis and design. Large radar should be designed by bearing the 75 knot wind force and $20kg/m^2$ ice mass as operating conditions in order to meet structural stability, and driving torque and bearing load were calculated for securing the driving stability. Thermal dissipation analysis was performed considering TRM and DC-DC Converter's limitation temperature by $50^{\circ}C$ ambient temperature condition in order to attain thermal stability, and PSD and shock analysis were carried out by using MIL-STD-810G vibration and shock specification in order to transport and installation of the large radar. As a result, all components of large radar could secure the structural stability more than 2.8 factor of safety, and driving stability was also secured with adequate bearing fatigue life. Thermal stability was attained by allowable max temperature 88.7 C of the TRM, and structural stability for transportation and installation of the large radar was also secured more than 5 factor of safety. After it was transported and installed to the radar site, operating capability was finally verified by rotating the large radar.

A Development of Simplified Design Method of the Detention Pond for the Reduction of Runoff (우수유출저감용 저류지의 간편설계기법 개발)

  • Lee, Jae-Joon;Kwak, Chang-Jae
    • Journal of Korea Water Resources Association
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    • v.41 no.7
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    • pp.693-700
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    • 2008
  • Detention pond has an important role in peak flow reduction to mitigate flood damage. Design of detention pond is accomplished through the preliminary stage, and design stage in general. New development projects produce increased peak flow and flow amounts. In this case it is necessary to design the detention pond easily and simply. A simplified design method of the detention pond is suggested in this study. Used design variables are peak flow ratio(${\alpha}$) and storage ratio($S_r$). ${\alpha}$ is the peak flow ratio of before and after development of the basin. $S_r$ is a ratio of storage volume to total runoff volume. Applicability of the proposed method was also proved. The simple procedure of detention pond design is proposed in this study.

Effects of Weed Interference and Starter Fertilizer on Subsequent Seed Germination and Vigour of Soybean (Glycine max [L.] Merr.)

  • Mohammadi, G.R.;Amiri, F.
    • Korean Journal of Weed Science
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    • v.32 no.1
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    • pp.17-24
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    • 2012
  • The study was conducted to investigate the effect of weed interference and starter fertilizer on subsequent soybean seed quality at the Agricultural Research Farm and Laboratory of Razi University, Kermanshah, Iran. Two factorial experiment was laid-outon a randomized complete block design with four replications. First factor was starter fertilizer levels (0 and 25 kg $ha^{-1}$) applied in the forms of monoammonium phosphate, the second factor was different weed interference periods consisted of five initial weed-free periods (in which, plots were kept free of weeds for 0, 15, 30, 45 and 60 days after crop emergence (DAE) and then weeds were allowed to grow until harvest) and five initial weed-infested periods (in which, weeds were allowed to grow for 0, 15, 30, 45 and 60DAE, after which the plots were kept free of weeds until harvest). Full season weedy condition reduced 100-seed weight, seed germination percentage and seedling dry weight by 25.9, 13.3 and 22.5%, respectively and increased mean germination time and seed electrical conductivity by 55.8 and 24.3%, respectively as compared with full season weed-free control. However, the traits under study were not significantly influenced when field was kept free of weeds for at least 45 DAE (R1) or weedy condition was continued for less than 30 DAE (V8). There was a significant and negative correlation between weed biomass and seed weight (r = -0.93), so that when weed free condition was less than 45 DAE or weed infested period was continued for at least 30 DAE, soybean plants produced wrinkled and underdeveloped seeds with lower weights and qualities. Moreover, soybean seed quality reduction due to weed interference was more evident when starter fertilizer was applied and weeds interfered with soybean from the beginning of the growing season. Information from the present study is beneficial in soybean seed production systems and where farmers use the harvested seeds for the following planting.