• Title/Summary/Keyword: $R_max$

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DMAC implementation On $Excalibur^{TM}$ ($Excalibur^{TM}$ 상에서의 DMAC 구현)

  • Hwang, In-Ki
    • Proceedings of the KIEE Conference
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    • 2003.11c
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    • pp.959-961
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    • 2003
  • In this paper, we describe implemented DMAC (Direct Memory Access Controller) architecture on Altera's $Excalibur^{TM}$ that includes industry-standard $ARM922T^{TM}$ 32-bit RISC processor core operating at 200 MHz. We implemented DMAC based on AMBA (Advanced Micro-controller Bus Architecture) AHB (Advanced Micro-performance Bus) interface. Implemented DMAC has 8-channel and can extend supportable channel count according to user application. We used round-robin method for priority selection. Implemented DMAC supports data transfer between Memory-to-Memory, Memory-to-Peripheral and Peripheral-to-Memory. The max transfer count is 1024 per a time and it can support byte, half-word and word transfer according to AHB protocol (HSIZE signals). We implemented with VHDL and functional verification using $ModelSim^{TM}$. Then, we synthesized using $LeonardoSpectrum^{TM}$ with Altera $Excalibur^{TM}$ library. We did FPGA P&R and targeting using $Quartus^{TM}$. We can use implemented DMAC module at any system that needs high speed and broad bandwidth data transfers.

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TWO-SIDED BEST SIMULTANEOUS APPROXIMATION

  • Rhee, Hyang Joo
    • Journal of the Chungcheong Mathematical Society
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    • v.23 no.4
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    • pp.705-710
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    • 2010
  • Let $C_1(X)$ be a normed linear space over ${\mathbb{R}}^m$, and S be an n-dimensional subspace of $C_1(X)$ with spaned by {$s_1,{\cdots},s_n$}. For each ${\ell}$- tuple vectors F in $C_1(X)$, the two-sided best simultaneous approximation problem is $$\min_{s{\in}S}\;\max\limits_{i=1}^\ell\{{\parallel}f_i-s{\parallel}_1\}$$. A $s{\in}S$ attaining the above minimum is called a two-sided best simultaneous approximation or a Chebyshev center for $F=\{f_1,{\cdots},f_{\ell}\}$ from S. This paper is concerned with algorithm for calculating two-sided best simultaneous approximation, in the case of continuous functions.

Application of Proteolytic Enzymes in Fruits for Meat Tenderization (과일에 존재하는 단백질 분해효소의 식육연화효과에 관한 연구)

  • 배영희;노정해
    • Korean journal of food and cookery science
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    • v.16 no.4
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    • pp.367-371
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    • 2000
  • In order to study the tenderizing effect of proteolytic enzymes in fruits, beef(M. semimembranosus) was marinated with meat sauce containing each fruit juices. After cooking, the shear force was measured by Rheometer and evaluated the sensory properties of beef by quantitative descriptive analysis method. The results are as follows: 1. The combination ratio of meat sauce:water was 2:1 with pH 5.0∼5.5 showed the max. tenderness. 2. As a result of shear force test, the decrease of shear force was pineapple>papaya>fig>kiwifruit>pear: especially, pineapple, papaya and fig tendered the beef significantly comparing with pear and kiwifruit at p<0.001. 3. The tendering effect of pineapple and papaya on the meat showed significant difference (p<0.01) comparing with pear in tenderness and overall acceptability by sensory evaluation; and there was a significant difference between pear and papaya in taste (p<0.05). 4. There was highly significant correlation between mechanical tenderness and sensory properties: correlation of fruit and mechanical tenderness was -.877(p<0.01); between mechanical tenderness and overall acceptability, r = .532(p<0.01); between fruit and sensory tenderness, r = .495(p<0.01); between mechanical tenderness and sensory tenderness, r = .490(p<0.01). At p<0.05, between taste and juiciness, r = .208.

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Responses of Growth Characteristics of Soybean [Glycine max (L.) Merr.] Cultivars to Riptortus clavatus Thunberg (Hemiptera: Alydidae) (콩 톱다리개미허리노린재 피해와 관련형질의 품종간 차이)

  • Oh, Young-Jin;Cho, Sang-Kyun;Kim, Kyong-Ho;Paik, Chae-Hoon;Cho, Youngkoo;Kim, Hong-Sik;Kim, Tae-Soo
    • Korean Journal of Breeding Science
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    • v.41 no.4
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    • pp.488-495
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    • 2009
  • In recent years, an increasing amount of research has been conducted on the yield loss of soybean crop caused by Riptortus clavatus, a serious pest of legumes. The objective of this study were to examine crop damage caused by various population densities of R. clavatus and determine the association of unique growth and seed characteristics with crop damage rate in conventional soybean fields. Major growth responses to R. clavatus were examined. The cultivars that were not as seriously damaged by R. clavatus were Pungsannamulkong, Sobaegknamulkong, Duyoukong, and Sinpaldal 2, but Myeongjunamulkong, Mallikong, and Hwangkeumkong were significantly (P<0.05) damaged. The rate of seed damage caused by R. clavatus was 8.2% in a group of brown colored pubescence, while the rate was 13.0% in a group of the gray colored. Crop damage by R. clavatus clearly more reduced in cultivars with dark hilum colors including dark brown, brown, and grayish brown than those with yellow hilum colors. Concerning pod colors, crop damage was less significant in cultivars with dark brown pod color than with the light brown. Cultivars with short pod length (4.0-4.5 cm) at full seed (R6) stage showed lower seed damage rates by R. clavatus than those with long pod length (>5.6 cm). Therefore, characteristics of hilum, pod, pubescence colors, and pod length were significantly related and linked to the cultivar resistance to R. clavatus.

Mathematical Models to Predict Staphylococcus aureus Growth on Processed Cheeses

  • Kim, Kyungmi;Lee, Heeyoung;Moon, Jinsan;Kim, Youngjo;Heo, Eunjeong;Park, Hyunjung;Yoon, Yohan
    • Journal of Food Hygiene and Safety
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    • v.28 no.3
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    • pp.217-221
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    • 2013
  • This study developed predictive models for the kinetic behavior of Staphylococcus aureus on processed cheeses. Mozzarella slice cheese and cheddar slice cheese were inoculated with 0.1 ml of a S. aureus strain mixture (ATCC13565, ATCC14458, ATCC23235, ATCC27664, and NCCP10826). The inoculated samples were then stored at $4^{\circ}C$ (1440 h), $15^{\circ}C$ (288 h), $25^{\circ}C$ (72 h), and $30^{\circ}C$ (48 h), and the growth of all bacteria and of S. aureus were enumerated on tryptic soy agar and mannitol salt agar, respectively. The Baranyi model was fitted to the growth data of S. aureus to calculate growth rate (${\mu}_{max}$; ${\log}CFU{\cdot}g^{-1}{\cdot}h^{-1}$), lag phase duration (LPD; h), lower asymptote (log CFU/g), and upper asymptote (log CFU/g). The growth parameters were further analyzed using the square root model as a function of temperature. The model performance was validated with observed data, and the root mean square error (RMSE) was calculated. At $4^{\circ}C$, S. aureus cell growth was not observed on either processed cheese, but S. aureus growth on the mozzarella and cheddar cheeses was observed at $15^{\circ}C$, $25^{\circ}C$, and $30^{\circ}C$. The ${\mu}_{max}$ values increased, but LPD values decreased as storage temperature increased. In addition, the developed models showed acceptable performance (RMSE = 0.3500-0.5344). This result indicates that the developed kinetic model should be useful in describing the growth pattern of S. aureus in processed cheeses.

Kit Preparation and Biodistribution of $Bz-MAG_3$ (benzoylmercaptoacetylglycylglycylglycine) for Renal Imaging (신장기능영상용 방사성의 약품 $Bz-MAG_3$(Benzoylmercaptoacetylglycylglycylglycine) 의 키트화 및 체내분포)

  • Kim, Young-Ju;Jeong, Jae-Min;Cho, Jung-Hyuk;Chang, Young-Soo;Lee, Dong-Soo;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.3
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    • pp.367-371
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    • 1996
  • The $MAG_3$ is a tubular excreting radiopharmaceutical for renal image. We synthesized benzoyl $MAG_3\;(Bz-MAG_3)$ and made a kit for labeling with $^{99m}Tc$. We checked the labeling efficieny of $^{99m}Tc$ labeled $MAG_3$ and biodistribution. Labeling efficieny was checked by TLC-SG (acetonitrile/$H_2O$=2/1). After injecting of 1 mCi of $^{99m}Tc-MAG_3$ to ICR-mice, $T_{max}(min),\;T_{1/2}(min)$ were obtained in the renogram. Sequential images (30sec, 2min, 5min, 10min, 15min, 20min) of $^{99m}Tc-MAG_3$ were compared with those of commercial $^{99m}Tc$-DTPA (Du Pont Merck Pharmaceutical Co.) kit. 1) The $R_f$ value of synthesized $^{99m}Tc-MAG_3$ was 0.78 and labeling efficiency was $97.5{\pm}1.9%$ (n=10). 2) The dynamic images of the $^{99m}Tc-MAG_3$ were better than those of the $^{99m}Tc$-DTPA. 3) The $T_{max}(min.)$ and $T_{1/2}(min.)$ of $^{99m}Tc-MAG_3$ (n=10) were $1.5{\pm}0.5$ (left), $1.4{\pm}0.4$ (right), and $4.3{\pm}1.4$ (left), $4.8{\pm}2.0$ (right), respectively. The $T_{max}(min.)$ and $T_{1/2}(min.)$ of $^{99m}Tc$-DTPA (n=7) were $2.7{\pm}1.6$ (left), $2.7{\pm}1.6$ (right), and $3.8{\pm}1.7$ (left), $4.5{\pm}2.7$ (right), respectively. The quaility of image and labeling efficiency of the synthesized $Bz-MAG_3$ kit were excellent, that it was supposed to be used in routine clinical work.

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Development of a predictive model describing the growth of Staphylococcus aureus in processed meat product galbitang (식육추출가공품 중 갈비탕에서의 Staphylococcus aureus 성장예측모델 개발)

  • Son, Na-Ry;Kim, An-Na;Choi, Won-Seok;Yoon, Sang-Hyun;Suh, Soo-Hwan;Joo, In-Sun;Kim, Soon-Han;Kwak, Hyo-Sun;Cho, Joon-Il
    • Korean Journal of Food Science and Technology
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    • v.49 no.3
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    • pp.274-278
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    • 2017
  • In this study, predictive mathematical models were developed to estimate the kinetics of Staphylococcus aureus growth in processed meat product galbitang. Processed meat product galbitang was inoculated with 0.1 mL of S. aureus culture and stored at 4, 10, 20, $37^{\circ}C$. The ${\mu}_{max}$ (maximum specific growth rate) and LPD (lag phase duration) values were calculated. The primary model was used to develop a response surface secondary model. The growth parameters were analyzed using the square root model as a function of storage temperature. The developed model was confirmed by calculating RMSE (Root Mean Square Error) values as statistic parameters. The LPD decreased, but ${\mu}_{max}$ increased with an increase in the storage temperature. At 4, 10, 20 and $37^{\circ}C$, $R^2$ was 0.99, 0.98, 0.99 and 0.99, respectively; RMSE was 0.39. The developed predictive growth model can be used to predict the risk of S. aureus contamination in processed meat product galbitang; hence, it has potential as an input model for the risk assessment.

Bioequivalence Evaluation of Two Cefquinome 2.5% Injectable Products in Piglets (돼지에서 두 가지 Cefquinome 2.5% 제제의 생물학적 동등성 평가)

  • Song, In-Bae;Kim, Tae-Won;Lee, Hong-Gee;Kim, Myoung-Seok;Hwang, Youn-Hwan;Park, Byung-Kwon;Lim, Jong-Hwan;Yun, Hyo-In
    • Journal of Veterinary Clinics
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    • v.29 no.3
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    • pp.233-236
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    • 2012
  • Cefquinome, a fourth generation cephalosporin, has been solely used for veterinary medicine and has a broad antibacterial spectrum against gram-negatives and gram-positives being very stable to ${\beta}$-lactamases. This study was conducted to evaluate the bioequivalence of two cefquinome 2.5% products in piglets. Plasma cefquinome concentrations were analyzed by liquid chromatography-mass spectrometry (LC/MS). Mean maximum concentration ($C_{max}$) of test product ($Cequus^{(R)}$) and reference product ($Cobactan^{(R)}$) were $4.34{\pm}0.58$ and $4.22{\pm}0.47{\mu}g/mL$, and mean area under the concentration time curve ($AUC_{0{\rightarrow}{\infty}}$) values were $10.43{\pm}1.96$ and $10.25{\pm}2.98{\mu}g{\cdot}h/mL$, respectively. The 90% confidence intervals for the ratio of $C_{max}$ (0.941-1.115), and $AUC_{0{\rightarrow}{\infty}}$ (0.927-1.172) values for the test and reference products were within the acceptable bioequivalence limit of 0.80-1.25. It is concluded that two commercial cefquinome injectable solutions are bioequivalent in their extent of drug absorption in piglets.

PERIODIC AND CORRELATION ANALYSES BETWEEN WATER TEMPERATURE AND AIR TEMPERATURE IN THE KOREAN WATERS (韓國 沿岸 水溫 및 氣溫의 週期分析과 相關分析)

  • Kim, Bok-Kee
    • 한국해양학회지
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    • v.18 no.1
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    • pp.55-63
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    • 1983
  • The study on the periodic and correlation analysis between water temperature and air temperature has beenconducted by oceanographic data obtained from 1923 to 1979 (For 16-51 years) in 6 ststions in the Korean Waters. The periodic and correlation analyses has been examined by method of he Schuster's and the quadratic formula of least squares method, respectively. The results pbtained from the study are as follows; 1. Periodic analysis 1) The yearly difference between max. and mini. fo surface water temperature was 12.77-17.99$^{\circ}C$ (computed value : 11.67-16.64$^{\circ}C$) in offshore waters, and was 15.72-26.33$^{\circ}C$ (computed value : 15.13-25.29$^{\circ}C$) in inshore waters, and that of air temperature was 21.71-28.60$^{\circ}C$ (computed value : 10.50-27.22$^{\circ}C$). 2) The yearly mean of water temperature by station was 11.25-18.78$^{\circ}C$, and that of air temperature was 11.39-16.16$^{\circ}C$. 3) The annual compnent amplitrde of water temperature was 5.72-12.54$^{\circ}C$, and that of air temperature was 10.04-13.49$^{\circ}C$. 4) The semi-annual component amplitude of water temperature was 0.83-1.30$^{\circ}C$, and that of air temperature was 0.72-1.26$^{\circ}C$. 5) The annual component phase of water temperature was 215-228$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in inshore waters and 138-244$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in offshore waters, and that of air temperarture was 212-221$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of July and in the first tin days of August). 6) The semi-annual component phase of water temperature was 87-110$^{\circ}C$ in offshore waters, and 167-212$^{\circ}C$ in inshore waters, and that of air temperature was 156-189$^{\circ}C$. 2. Correlation analyses of water temperature and air temperature before one month. 1) When the water temperature is in rising time, the quadratic constant of correlation formual was the gradual inreasing type ( constant; 0.010-0.026) in offshore waters, and the gradual decreasing or proportional type (constant; -0.020-0.001) in inshore waters. 2) when the water temperature is in descending time, the quadratic constant of correlation formula was the gradual increasing type (constant: 0.012-0.021) 3) the determination coefficient was 0.964-0.992 at rising time and 0.982-0.999 at descending time of water temperature.

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Changes in $A_{1}$, Adenosine Receptor-Adenylyl Cyclase System of Rat Adipocytes Fellowing Induction of Experimental Diabetes by Streptozotocin Treatment (Streptozotocin으로 당뇨병을 유발시킨 쥐의 지방세포에 나타나는 $A_{1}$, Adenosine Receptor-Adenylyl Cyclase System의 변화)

  • Park, Kyung-Sun;Lee, Myung-Soon;Kim, Kyung-Hwan
    • The Korean Journal of Pharmacology
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    • v.29 no.1
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    • pp.97-105
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    • 1993
  • Adenosine receptors in rat adipose tissues have been reported to be of $A_{1}$ subclass, and their stimulation leads to inhibition of adenylyl cyclase, resulting in inhibition of lipolysis. In the present study we investigated changes in $A_{1}$ adenosine receptor-adenylyl cyclase system of adipocytes following induction of experimental diabetes in rats. One week following experimental diabetes were induced by intravenous injection of streptozotocin (50 mg/kg body wt.), adipocytes from rats $(170{\sim}230g)$ fed ad libitum were isolated using collagenase. When adipocytes were incubated for 1 h with 1 unit/ml adenosine deaminase and $1\;{\mu}M$ isoproterenol, and assayed for glycerol formation, it was found that the inhibition of lipolysis in diabetic adipocytes by $(-)-N^{6}-(R-phenylisopropyl)adenosine$ (PIA), an $A_{1}$, adenosine receptor agonist, was twice that of control adipocytes. In an effort to delineate the mechanism(s), $[^{3}H]PIA$ binding to adipocytic membranes from diabetic and control rats were determined. Neither the affinities nor numbers of $A_{1}$ adenosine receptor were significantly different from each other (Best fit parameters for the one-site model are: $K_{d}=0.51{\pm}0.09nM$ and $B_{max}=1.60{\pm}0.12\;pmoles/mg$ protein for control membranes; $K_{d}=0.54{\pm}0.21\;nM$ and $B_{max}=1.72{\pm}0.31\;pmoles/mg$ protein for diabetic membranes). However, the inhibiton by PIA of the isoproterenol-stimulated adenylyl cyclase activities was found to be 1.9 times higher in adipocytic membranes from diabetic rats than those from controls. These results suggest that the increased sensitivity of inhibition of lipolysis to PIA in adipocytic membranes from diabetic rats is due to changes in signal transduction pathways, rather than alterations of $A_{1}4 adenosine receptor molecules themselves.

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