• Parasites, Hosts and Diseases
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• v.39 no.1
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• pp.67-76
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• 2001

This experiment was focused on the characterization of anti- Toxoplasma monoclonal antibodies (mAbs) and the effect of mAbs on the parasite invasion of mouse peritoneal macrophages. Twenty eight mAbs including M110, M556, R7A6 and M62l were characterized by Ab titer, immunoglobulin isotyping and western blot pattern. Antibody titer (optical density) of 4 mAbs. Ml 10. M556. R7A6 and M62l. were 0.53,0.67, 0.45 and 0.39 (normal mouse serum; 0.19) with the same IgGl isotypes shown by Enzyme-linked immunosorbent assay (ELISA). Western blot analysis showed that Ml 10. M556. R7A6 and M62l reacted with the 33 kDa (p30),31 kDa (p28),43 kDa and 36 kDa protein. Immuno-gold labelling of mAbs M110, M556, R7A6 and M621 reacted with the surface membrane, dense granules and parasitophorous vacuolar membrane (PVM) , rhoptries and cytoplasm of tachyzoite, respectively. For in vitro assay, preincubation of tachyzoties with four mAbs, Ml 10, M556, R7A6 and M62l resulted in the decrease of the number of infected macrophages (p < 0.05) and the suppression of parasite multiplication at 18 h post-infection. Four monoclonal antibodies including Ml 10 (SAGI) were found to have an important role in the inhibition of macrophage invasion and T. gondii multiplication in vitro, and these mAbs may be suitable for vaccine candidates, diagnostic kit and for chemotherapy.

• Journal of the Korean Mathematical Society
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• v.61 no.2
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• pp.309-339
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• 2024

Let M be a real hypersurface in the complex hyperbolic quadric Q^m*, m ≥ 3. The Riemannian curvature tensor field R of M allows us to define a symmetric Jacobi operator with respect to the Reeb vector field ξ, which is called the structure Jacobi operator R_ξ = R( · , ξ)ξ ∈ End(TM). On the other hand, in [20], Semmelmann showed that the cyclic parallelism is equivalent to the Killing property regarding any symmetric tensor. Motivated by his result above, in this paper we consider the cyclic parallelism of the structure Jacobi operator R_ξ for a real hypersurface M in the complex hyperbolic quadric Q^m*. Furthermore, we give a complete classification of Hopf real hypersurfaces in Q^m* with such a property.

• Journal of Ginseng Research
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• v.27 no.3
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• pp.129-134
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• 2003

When ginsenoside $R_{*}$b1/ and $R_{b2}$ were anaerobically incubated with human fecal microflora, these ginsenosides were metabolized to compound K (IH-901). When ginsenoside $R_{g3}$ was anaerobically incubated with human fecal microflora, the ginsenoside $R_{g3}$ was metabolized it to ginsenoside $R_{h2}$. Among ginsenosides, IH-901 and 20(S)-ginsenoside $R_{h2}$ exhibited the most potent cyotoxicity against tumor cells: 50% cytotoxic concentrations of IH-901 in the media with and without fetal bovine serum (FBS) were 27.1-31.6 $\mu$M and 0.1-0.61 $\mu$M, and those of 20(S)-ginsenoside $R_{h2}$ were 37.5->50 and 0.7-7.1 $\mu$M, respectively. The cytotoxic potency of ginsenosides was IH-901>20(S)-ginsenoside R $h_{h2}$》20(S)-ginsenoside $R_{g3}$>ginsenoside $R_{b1}$(equation omitted) $R_{b2}$.EX>$R_{b2}$./.

• Journal of Korean Society for Atmospheric Environment
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• v.29 no.2
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• pp.211-216
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• 2013

For diffusion limited cluster agglomerates the ratio of the mobility radius to the radius of gyration $R_m/R_g$ vs. N and the ratio of the mobility radius to the radius of primary particle $R_m$/a are determined using experimental data obtained with DMA-APM and tandem DMA over a range of Knudsen numbers extending into the transition region where there is a lack of data. It was found that in slip regime with the number of primary particles between 100 and 400, datapoints are found to be between the two asymptotic lines for the continuum and free molecular regimes as those datapoints are plotted in both $R_m/R_g$ vs. N and $R_m$/a vs. N.

• Kyungpook Mathematical Journal
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• v.48 no.1
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• pp.143-154
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• 2008

Lomp [9] has studied finitely generated projective modules over semilocal rings. He obtained the following: finitely generated projective modules over semilocal rings are semilocal. We shall give necessary and sufficient conditions for finitely generated modules to be semilocal modules. By using a lifting property, we also give characterizations of right perfect (semiperfect) rings. Our main results can be summarized as follows: (1) Let M be a finitely generated module. Then M has finite hollow dimension if and only if M is weakly supplemented if and only if M is semilocal. (2) A ring R is right perfect if and only if every flat right R-module is lifting and every right R-module has a flat cover if and only if every quasi-projective right R-module is lifting. (3) A ring R is semiperfect if and only if every finitely generated flat right R-module is lifting if and only if RR satisfies the lifting property for simple factor modules.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.1
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• pp.33-46
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• 2010

We investigated and estimated at the characteristics of decomposition and by-products of N-Nitrosodimethylamine (NDMA) using a design of experiment (DOE) based on the Box-Behken design in an UV process, and also the main factors (variables) with UV intensity($X_2$) (range: $1.5{\sim}4.5\;mW/cm^2$), NDMA concentration ($X_2$) (range: 100~300 uM) and pH ($X_2$) (rang: 3~9) which consisted of 3 levels in each factor and 4 responses ($Y_1$ (% of NDMA removal), $Y_2$ (dimethylamine (DMA) reformation (uM)), $Y_3$ (dimethylformamide (DMF) reformation (uM), $Y_4$ ($NO_2$-N reformation (uM)) were set up to estimate the prediction model and the optimization conditions. The results of prediction model and optimization point using the canonical analysis in order to obtain the optimal operation conditions were $Y_1$ [% of NDMA removal] = $117+21X_1-0.3X_2-17.2X_3+{2.43X_1}^2+{0.001X_2}^2+{3.2X_3}^2-0.08X_1X_2-1.6X_1X_3-0.05X_2X_3$ ($R^2$= 96%, Adjusted $R^2$ = 88%) and 99.3% ($X_1:\;4.5\;mW/cm^2$, $X_2:\;190\;uM$, $X_3:\;3.2$), $Y_2$ [DMA conc] = $-101+18.5X_1+0.4X_2+21X_3-{3.3X_1}^2-{0.01X_2}^2-{1.5X_3}^2-0.01X_1X_2+0.07X_1X_3-0.01X_2X_3$ ($R^2$= 99.4%, 수정 $R^2$ = 95.7%) and 35.2 uM ($X_1$: 3 $mW/cm^2$, $X_2$: 220 uM, $X_3$: 6.3), $Y_3$ [DMF conc] = $-6.2+0.2X_1+0.02X_2+2X_3-0.26X_1^2-0.01X_2^2-0.2X_3^2-0.004X_1X_2+0.1X_1X_3-0.02X_2X_3$ ($R^2$= 98%, Adjusted $R^2$ = 94.4%) and 3.7 uM ($X_1:\;4.5\;$mW/cm^2$, $X_2:\;290\;uM$, $X_3:\;6.2$) and $Y_4$ [$NO_2$-N conc] = $-25+12.2X_1+0.15X_2+7.8X_3+{1.1X_1}^2+{0.001X_2}^2-{0.34X_3}^2+0.01X_1X_2+0.08X_1X_3-3.4X_2X_3$ ($R^2$= 98.5%, Adjusted $R^2$ = 95.7%) and 74.5 uM ($X_1:\;4.5\;mW/cm^2$, $X_2:\;220\;uM$, $X_3:\;3.1$). This study has demonstrated that the response surface methodology and the Box-Behnken statistical experiment design can provide statistically reliable results for decomposition and by-products of NDMA by the UV photolysis and also for determination of optimum conditions. Predictions obtained from the response functions were in good agreement with the experimental results indicating the reliability of the methodology used.

• Microbiology and Biotechnology Letters
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• v.35 no.4
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• pp.285-291
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• 2007

Enantioconvergent hydrolysis process for the preparation of chiral diol from racemic epoxides by using the recombinant Caulobacter crescentus epoxide hydrolase (CcEH) in Escherichia coli BL21 (DE3) was optimized. For the optimization, the effects of detergent, temperature and product inhibition on the enantiopurity and the yield of diol were investigated. (R)-phenyl-1,2-ethanediol with 92% enantiomeric excess and 56% yield from 20 mM racemic styrene oxide was obtained by using the recombinant CcEH at the optimal condition of $10^{\circ}C$ and the addition of 2% (w/v) Tween 80. At 50 mM racemic styrene oxide was used as a substrate, (R)-phenyl-1,2-ethanediol was obtained with 87% enantiomeric excess and 77% yield. Racemic phenyl-1,2-ethanediol, (R)-phenyl-1,2-ethanediol and (S)-phenyl-1,2-ethanediol dramatically inhibited the hydrolytic activity of the recombinant CcEH. These results suggested that another EH with the regioselectivity on ${\beta}$-position of (R)-enantiomer and without feedback inhibition by products would be needed as the partner EH of C. crescentus EH.

• Journal of Environmental Health Sciences
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• v.30 no.5 s.81
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• pp.402-409
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• 2004

I performed the research about the drinking water treatment by precoat filtration and activated carbon adsorption process in the D water treatment plant at Gwangju. D water treatment plant inlet water is supplied from Juam lake in Jeollanamdo. The results are as follows; 1. Element disk used in this experiment are R(pore size $10{\mu}m$), B(pore size $20{\mu}m$). And diatomaceous earth are A(cake pore size $3.5{\mu}m$), B(cake pore size $7{\mu}m$) and C(cake pore size $17{\mu}m$) 2. Filtrate of precoat filter during 30 min are B-C 10.2 > BB 5.7 > R-A 5.4 ($m^3/m^2$). 3. The water quality through B-C+AC and R-A+AC are DOC 1.76 mg/1, 1.288 m/l respectively. 4. total THMs produced by chlorination are $84.2{\mu}g/l$(B-C+AC), $66.11{\mu}g/l$ (R-A+AC), $97{\mu}g/l$ (rapid sand filtration water) respectively. 5. The R-A+AC and B-C+AC process can be substitute of CWTS.

• Journal of the Korean Magnetics Society
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• v.3 no.2
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• pp.115-120
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• 1993

The relationship between magnetic parameter and microwave absorbing performance evaluation factor of electomagnetic wave absorber such as matching frequency, matching thickness were investigated for Ni-Zn ferrite composites. It was identified that the maximum value of ${\mu}_{r}$" is shift to low frequency with decrese Ni/Zn ratio and the value of ${\mu}_{r}$" is maximum in the case of Ni/Zn=1. All Ni-Zn ferrite composites in this study have two matching frequencies in 1-12 GHz frequency. It can be suggested that $f_{m1}$ is proportional to resonance frequency and $f_{m2}$ is proportional to the saturation magnetization.

• Bulletin of the Korean Chemical Society
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• v.14 no.1
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• pp.113-117
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• 1993

Good yield synthetic routes for the production of new B-alkyl-dithiaborane clusters are reported. The syntheses of the B-alkyl-dithiaboranes are based on the use of Fischer-type carbene reagents to activate the B-H bonds of dithiaborane for alkyl-addition reactions and are the first examples of transition-mediated reactions of dithiaborane to be reported. Thus, reactions employing arachno-$S_2B_7H_8$- and $(CO)_5M{C(R_1)R_2}$ (M = Cr, W; $R_1 = CH_3,\;C_6H_5;\; R_2 = OCH_3,\;SC_6H_5)$ were found to yield the intermidiate anions I, $[(CO)_5M{C(R_1)R_2S_2B_7H_8}]^-$, which upon protonation gave the corresponding neutral, air-sensitive cluster arachno-4-$RCH_2-6,8-S_2B_7H_8(R=CH_3,\;IIa;\;C_6H_5,\;IIb)$ range from 30 to 35% yield. Complexes IIa and IIb are isoelectronic with arachno-6,8-$S_2B_7H_9$ and, on the basis of the spectroscopic data, are proposed to adopt a similar arachno cage geometry in which an $RCH_2$ units are substituted to 4 position boron atom of the arachno-6,8-$S_2B_7H_9$.