• 제목/요약/키워드: $PaO_2$

검색결과 515건 처리시간 0.026초

Effects of small tidal volume and positive end-expiratory pressure on oxygenation in pressure-controlled ventilation-volume guaranteed mode during one-lung ventilation

  • Byun, Sung Hye;Lee, So Young;Jung, Jin Yong
    • Journal of Yeungnam Medical Science
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    • 제35권2호
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    • pp.165-170
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    • 2018
  • Background: The purpose of this study was to investigate whether tidal volume (TV) of 8 mL/kg without positive end-expiratory pressure (PEEP) and TV of 6 mL/kg with or without PEEP in pressure-controlled ventilation-volume guaranteed (PCV-VG) mode can maintain arterial oxygenation and decrease inspiratory airway pressure effectively during one-lung ventilation (OLV). Methods: The study enrolled 27 patients undergoing thoracic surgery. All patients were ventilated with PCV-VG mode. During OLV, patients were initially ventilated with TV 8 mL/kg (group TV8) without PEEP. Ventilation was subsequently changed to TV 6 mL/kg with PEEP ($5cmH_2O$; group TV6+PEEP) or without (group TV6) in random sequence. Peak inspiratory pressure ($P_{peak}$), mean airway pressure ($P_{mean}$), and arterial blood gas analysis were measured 30 min after changing ventilator settings. Ventilation was then changed once more to add or eliminate PEEP ($5cmH_2O$), while maintaining TV 6 mL/kg. Thirty min after changing ventilator settings, the same parameters were measured once more. Results: The $P_{peak}$ was significantly lower in group TV6 ($19.3{\pm}3.3cmH_2O$) than in group TV8 ($21.8{\pm}3.1cmH_2O$) and group TV6+PEEP ($20.1{\pm}3.4cmH_2O$). $PaO_2$ was significantly higher in group TV8 ($242.5{\pm}111.4mmHg$) than in group TV6 ($202.1{\pm}101.3mmHg$) (p=0.044). There was no significant difference in $PaO_2$ between group TV8 and group TV6+PEEP ($226.8{\pm}121.1mmHg$). However, three patients in group TV6 were dropped from the study because $PaO_2$ was lower than 80 mmHg after ventilation. Conclusion: It is postulated that TV 8 mL/kg without PEEP or TV 6 mL/kg with $5cmH_2O$ PEEP in PCV-VG mode during OLV can safely maintain adequate oxygenation.

Effects of Drain Bias on Memory-Compensated Analog Predistortion Power Amplifier for WCDMA Repeater Applications

  • Lee, Yong-Sub;Lee, Mun-Woo;Kam, Sang-Ho;Jeong, Yoon-Ha
    • Journal of electromagnetic engineering and science
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    • 제9권2호
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    • pp.78-84
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    • 2009
  • This paper represents the effects of drain bias on the linearity and efficiency of an analog pre-distortion power amplifier(PA) for wideband code division multiple access(WCDMA) repeater applications. For verification, an analog predistorter(APD) with three-branch nonlinear paths for memory-effect compensation is implemented and a class-AB PA is fabricated using a 30-W Si LOMaS. From the measured results, at an average output power of 33 dBm(lO-dB back-off power), the PA with APD shows the adjacent channel leakage ratio(ACLR, ${\pm}$5 MHz offset) of below -45.1 dBc, with a drain efficiency of 24 % at the drain bias voltage($V_{DD}$) of 18 V. This compared an ACLR of -36.7 dEc and drain efficiency of 14.1 % at the $V_{DD}$ of 28 V for a PA without APD.

태양전지응용을 위하여 MOCVD 방법으로 성장된 ZnO 박막의 기판온도에 따른 표면특성 (The Surface Morphology of ZnO Grown by Metal Organic Chemical Vapor Deposition for an Application of Solar Cell)

  • 김도영;강혜민;김형준
    • 한국진공학회지
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    • 제19권3호
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    • pp.177-183
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    • 2010
  • 우리는 MOCVD (metal organic chemical vapor deposition)법을 이용하여 DEZ (Diethylzinc)을 운송하는 Ar 유속과 reactant (반응물질)의 종류에 따른 ZnO 박막 증착을 연구하였다. Bubbler 시스템을 통하여 주입되는 Ar 유속에 의해 Zn 소스인 DEZ의 양이 조절된다. 산소 기체와 수증기는 산화를 위해 반응물질로 사용된다. 본 연구로부터 표면의 거칠기(surface roughness)는 반응물질의 종류와 DEZ Ar 유속에 관계되며 박막의 두께에 의존한다는 것을 알 수 있었다. 그러나 기판 온도는 산소를 반응물로 하는 상태에서는 표면 거칠기에 영향을 주지 못함을 알 수 있었다. 우리는 ZnO 박막이 90 sccm (Standard Cubic Centimeter per Minute)의 DEZ Ar 유속, 8 Pa의 수증기압, 그리고 $140^{\circ}C$의 기판 온도에서 39.16 mm의 가장 높은 거칠기를 가진다는 것을 확인할 수 있었다. 본 논문은 태양전지의 광 흡수층으로 사용가능한 ZnO 박막을 연구하였다.

유기산이 Escherichia coli O157:H7, Salmonella 및 Listeria monocytogenes의 증식에 미치는 영향 (Inactivation of Escherichia coli O157:H7, Salmonella and Listeria monocytogenes by Organic Acid)

  • 장재선;이혜정;오보영;이제만;고종명;김용희
    • 한국환경보건학회지
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    • 제33권5호
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    • pp.403-407
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    • 2007
  • The inhibitory effect of the food processing agent on growth of Escherichia coli O157:H7, Salmonella Enteritidis, and Listeria monocytogenes was performed with organic acid, and combination of citric acid, acetic acid, propionic acid and vanillic acid. The minimun inhibitory concentration(MIC) of propionic acid was 5,000 ppm in E. coli O157:H7, 2,500 ppm in Salmonella Enteritidis and Listeria monocytogenes. MIC of citric acid was 10,000 ppm in E. coli O157:H7 and Salmonella Enteritidis, 2,500 ppm in Listeria monocytogenes. MIC of acetic acid was 2,500ppm, while in vanillic acid was 5,000 ppm in Escherichia coli O157:H7, Salmonella Enteritidis, and Listeria monocytogenes. MIC of combined organc acid in E. coli O157:H7 were 2,500ppm in PC, 1,250 ppm in PA, PV, CA, CV and AV. MIC of combined organc acid in Salmonella Enteritidis were 2,500 ppm in PC, PA, PV, CA, and CV, 1,250 ppm in AV. MIC of combined organc acid in Listeria monocytogenes were 1,250 ppm in all treatment group. MIC of combined treatment of three organc acid in E. coli O157:H7, S. Enteritidis and L. monocytogenes were 1,250 ppm in PCA, PCV, PAV and CAV. The inhibitory effect of organc acid in E. coli O157:H7, S. Enteritidis and L. monocytogenes could be confirmed from the result of this experiment. Therefore, it was expected that the food process would increase or maintain by using organic acid.

서울시 대기 중 Pinic Acid와 cis-Pinonic Acid의 계절별 농도 변화 (Seasonal Variation of the Concentrations of Pinic Acid and cis-Pinonic Acid in the Atmosphere over Seoul)

  • 전소현;이지이;정창훈;김용표
    • 한국대기환경학회지
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    • 제32권2호
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    • pp.208-215
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    • 2016
  • Pinic acid (PA) and cis-pinonic acid (CPA) in the atmospheric particulate matter with an aerodynamic diameter of less than or equal to a nominal $10{\mu}m$ ($PM_{10}$) were analyzed for the samples collected during the period of April 2010 to April 2011 at Jongro in Seoul. Both pinic acid and cis-pinonic acid showed higher seasonal average concentrations in summer (PA; $18.9ng/m^3$, CPA; $16.0ng/m^3$) than winter (PA; $5.3ng/m^3$, CPA; $5.9ng/m^3$). They displayed a seasonal pattern associated with temperature reflecting the influence on emissions of ${\alpha}-pinene$ and ${\beta}-pinene$ from conifers and their photochemical reaction. These results were confirmed through Pearson correlation coefficient between CPA, PA and $O_3+NO_2$, temperature. CPA was only correlated with n-alkanes ($C_{29}$, $C_{31}$, $C_{33}$) from biogenic source. PA was correlated with n-alkanes ($C_{29}$, $C_{31}$, $C_{33}$), n-alkanoic acid ($C_{20}$, $C_{22}$, $C_{24}$) from biogenic source and n-alkanes ($C_{28}$, $C_{30}$, $C_{32}$), and n-alkanoic acid ($C_{16}$, $C_{18}$) from anthropogenic source. These results showed that the formation of PA and CPA from ${\alpha}-pinene$ and ${\beta}-pinene$ is related to organic compounds from biogenic source. And it is possible for PA to be effected by organic compounds from anthropogenic source.

YSZ(yttria-stabilized zirconia) 박막을 이용한 센서 셀의 산소 감응 (Oxygen detection of sensor cells based on YSZ (Yttria-Stabilized Zirconia) thin films)

  • 박준용;배정운;황순원;김기동;조영아;전진석;최동수;염근영
    • 한국진공학회지
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    • 제8권4B호
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    • pp.507-513
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    • 1999
  • 8mol%-yttria-stabilized zirconia(YSZ) thin films as oxygen ion conductor were deposited by rf-magnetron sputtering, and the oxygen gas sensors with the structure of $SiO_2$ substrate/Ni-NiO mixed reference layer/Pt/YSZ/Pt were fabricated and their oxygen sensing properties were investigated. The steady-state electro-motive force (EMF) values were measured as a function of oxygen partial pressure ($PO_2;form 1.013\times10^3 \textrm{Pa \;to}\; 1.013\times10^5$Pa) and operating temperature ($300^{\circ}C$ to $700^{\circ}C$). The fabricated YSZ oxygen sensor showed the best oxygen sensing properties at 50$0^{\circ}C$. However, oxygen sensing properties were very low at the temperature lower than 30$0^{\circ}C$ due to the lack of oxygen ion mobility and at the temperature higher than $700^{\circ}C$ due 새 intermixing of materials between the layers. Especially, the YSZ sensor operating at $500^{\circ}C$ and oxygen partial pressure above $1.565\times10^4$Pa showed the oxygen sensing properties close to the values predicted by ideal Nernst equation.

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인공폐(산화기) 제작과 실험 (Design & Animal Experiment of Artificial Oxygenator)

  • 김형묵
    • Journal of Chest Surgery
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    • 제15권2호
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    • pp.259-265
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    • 1982
  • We have designed a new type of bubble oxygenator (KOREA-KIM VENOTHERM OXYGENATOR) made of PVC sheet and deforming mesh incorporated in the heat exchanger, and evaluated in experimental animal for the analysis of it`s efficiency. The Oxygenator has low priming volume with high flow rate up to 6 L/rain, and efficiency of heat exchanger was excellent as 1-$1.5^{\circ}C.$ using total cardiopulmonary bypass method under moderate to deep hypothermia. Average priming volume of 1317 ml with 30% hemodilution method was perfused with an average of 1.1-3.0 L/min.$M^2$of arterial blood and pure oxygen at a rate of 2-3.4 L/min for 49.6 minutes continuously in average. During total cardiopulmonary bypass, average $PaO_2$ was $159.8{\pm}60$mmHg, $PaCO_2$ $41.0{\pm}3$mmHg respectively under $SaO_2$ over 96% with systolic arterial pressure of 70 mmHg and CVP of 5-10 cm$H_2O$. Plasma free Hemoglobin was $7.0{\pm}4$ mg/dl with 25% drop of hemoglobin and hematocrit at the end of cardiopulmonary bypass. This KKV Oxygenator was observed to have excellent capabillty of oxygen and carbon dioxide gas transfer with small amount of blood trauma, and the efficiency of heat exchanger was satisfactory during cooling and rewarming of the bubbled blood. Disadvantages have included the somewhat poor deforming effect due to loose PVC fiber mesh, the extracompact character of Teflon filters, and the rough inner surface of the heat exchanger copper pipes.

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적출된 작업성 쥐심장에서 Diltiazem 심정지액이 심근보호 및 심근기능 회복에 미치는 영향 (Effect of Diltiazem Cardioplegia on the Myocardial Protection and Functional Recovery of the Isolated Perfused Rat Heart)

  • 최종범
    • Journal of Chest Surgery
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    • 제21권6호
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    • pp.970-978
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    • 1988
  • There is tendency of increasing number and decreasing age of patients who are indicated for Rastelli operation for their cyanotic congenital heart disease. So there is the need to find the criterion which saves the patients from early postoperative hemodynamic disturbances. We reviewed the 26 patients who had been performed Rastelli operation at Seoul national University Hospital from January 1981 to June 1988. mean age of the patients was 7.8*3.4 years[range 2.5-15years], mean body surface area[BSA] 0.79*0.25m2[range 0.49-1.51m2] and mean hematocrit 57.95*12%[range 48-80%]. We divided these patients into survived group and died group before postoperative 72 hours, and analyzed preoperative arterial oxygen saturation[SaO2], the ratio of diameter of right pulmonary artery to ascending aorta[RPA/AA], the ratio of both right and left pulmonary artery diameter to descending thoracic aorta[RPA+LPA/DTA], pulmonary artery index[PA index], cardiopulmonary bypass time, aorta cross-clamping time, postoperative perfusion state and total amount of dopamine infused postoperatively. The results showed that RPA+LPA/DTA and PA index were statistically significant factors to influence early postoperative cardiac death rate[P< 0.05]. Especially there were good linear correlations between PA index[X] and peripheral perfusion index[Y][Y= - 1.15+0.02 X, r=0.86, P<0.01]and between PA index[X] and total amount of dopamine infused before postoperative 72 hours[mg/kg, Y][Y=61.94 - 0.15 X, r=-0.80, P < 0.01]. Also there were tendencies that the higher RPA+LPA/DTA[Y], the better peripheral perfusion [X] and the lower need of dopamine[X], but no statistical significance.[Y=0.78+1.60 X, r =0. 49, P >0.05] And the discriminate analysis showed that patients with PA index over 221 mm2/BSA could undergo correction with 25 per cent of error rate. In conclusion, early postoperative hemodynamic states could be predicted by preoperatively measured PA index, and which can be used as a criterion for Rastelli operation performed on cyanotic congenital heart disease.

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수용성 미셀용액에서 몇 가지 안트라센 유도체의 가용화 및 감광화 성질 (Solubilization and Photosensitizing Properties of Some Anthracene Derivatives in Aqueous Micellar Solutions)

  • 고정수;한동설;오형식;박병관;김종현;오세웅
    • 대한화학회지
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    • 제35권5호
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    • pp.452-460
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    • 1991
  • 메탄올-물 혼합용매 및 수용성 CTAB, SDS 용액에서 2-에틸안트라센[2-EA]과 9-페닐안트라센[9-PA]에 빛을 조사하는 동안 1,3-디페닐이소벤조푸란[DPBF]이 감소되는 것으로부터 이 반응에 단일항 산소$(^1O_2)$가 관여된다는 화학적 증거를 얻었다. 용매의 극성에 민간함 UV 분광학적 특성을 이용하여 2-EA와 9-PA의 평균미세환경의 극성을 조사하였다. 2-EA와 9-PA가 수용성 CTAB, SDS 및 Brij 35 용액에 가용화될 때 그들의 평균 미세환경은 극성이었으며, 미세환경의 극성 파라미터는 미셀의 이온성에 영향을 받지 않았다. 2-EA의 평균 미세환경의 극성은 40%(w/w) 에탄올 수용액의 극성과 비슷했으며, 9-PA의 경우는 30%(w/w)와 40%(w/w) 사이의 에탄올 수용액의 극성과 비슷했다. 이들 화학종들이 수용성 미셀용액에 가용화될 때 대부분 미셀의 표면에 분포할 것이라는 것을 알았다. 여러 용매에서 2-EA와 9-PA의 광증감능을 검토하였다. 메탄올-물 혼합용매가 수용성 미셀용액보다 광산화반응에 유리한 것으로 나타났다.

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여름철 파프리카 관비재배시 토양수분포텐셜이 과실품질 및 수량에 미치는 영향 (Effect of Soil Water Potential on the Fruit Quality and Yield in Fertigation Cultivation of Paprika in Summer)

  • 이한철;최경이;정재완;조명환;여경환;김다미;안철근;이동열
    • 생물환경조절학회지
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    • 제22권4호
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    • pp.378-384
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    • 2013
  • 파프리카의 토양재배면적 증가에 따라 관비재배법의 확립이 요구되고 있다. 관비재배(Fertigation)는 물과 양분을 함께 공급하는 방법으로 작물의 수분과 양분의 과부족에 의한 장해없이 근권을 안정적으로 유지할 수 있다. 본 연구에서는 시설 파프리카의 관비재배시 토양수 분포텐셜에 따른 과실 품질 및 수량의 효과를 구명코자 실험을 수행하였다. '쿠프라' 및 'E499524' 2품종을 공시하여 정식 후부터 수확기까지 토양수분포텐셜을 -10, -20 그리고 -30kPa로 처리구를 두었다. 초장은 토양수분포텐셜이 높은 -10kPa 처리구가 가장 길었다. 과실의 평균 과중은 '쿠프라' 품종에서는 평균과중은 -20kPa에서 154.5kg으로 가장 무거웠으며 토양수분포텐셜이 낮은 -30kPa에서는 138.2kg으로 가벼웠다. 주당 착과수는 5.1~5.3개로 '쿠프라' 품종은 토양수분포텐셜에 따른 차이가 없었으나 'E499524' 품종은 -20kPa 처리구에서 10.3개로 가장 많았다. 상품수량은 '쿠프라' 품종은 -20kPa 처리구에서 2,321kg/10a로 가장 많았고 그리고 'E499524' 품종은 -20kPa 처리구에서 1,147kg/10a로 가장 많았다. '쿠프라' 품종에서는 과장과 과폭은 토양수분포텐셜에 따른 차이가 없었으나 'E499524' 품종은 토양수분포텐셜이 낮을수록 작은 경향을 보였다. 과실의 당도는 '쿠프라' 품종에서는 4.4~4.9oBrix, 그리고 'E499524' 품종에서는 7.6~8.3oBrix로 토양수분포텐셜에 따른 통계적 유의차가 없었다. 자방수는 '쿠프라' 품종에서는 3.3~3.6개, 그리고 'E499524' 품종에서는 2.5~2.7개로 토양수분포텐셜 간에 유의차이가 없었다. 과실의 열과 발생율은 '쿠프라' 및 'E499524' 품종 모두 토양수분포텐셜 낮을수록 적은 경향을 보였다. 식물체 내 질소의 함량은 토양수분포텐셜에 따른 차이가 없었으며 '쿠프라' 품종은 2.10~2.22%였고 'E499524' 품종은 1.72~1.82%였다. '쿠프라' 및 'E499524' 품종 모두 토양수분포텐셜에 따른 식물체의 칼륨, 칼슘, 마그네슘 등 무기 양분의 함량은 유의차이가 없었다. 이상의 결과에서 파프리카의 여름철 관비재배시 토양수분포텐셜을 -20kPa로 설정하는 것이 생육이 가장 좋은 것으로 판단되었다.