• Journal of the Korean Wood Science and Technology
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• v.22 no.2
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• pp.46-53
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• 1994

This study was conducted to investigate a feasibility of manufacturing wood fiber thermoplastic composites and to evaluate their mechanical properties. Wood fiber as a potential reinforcing filler was compounded with two thermoplastics (polypropylene and high density polyethylene) in high intensity thermokinetic plastic mixer aided with a wetting agent. It was found that wood fiber thermoplastic composites could be manufactured by injection molding process. The tensile and flexural strength of injection molded specimens were improved greatly with increasing wood fiber concentration. Tensile and flexural modulus increased proportionately with wood fiber concentration. Wood fiber provided reinforcement with thermoplastics in terms of strength and modulus. However, the percent elongation at break and energy to break were reduced with increasing wood fiber loadings. Impact strength also showed similar trend.

• Korean Journal of Materials Research
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• v.15 no.11
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• pp.705-710
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• 2005

NIL (nanoimprint lithography) technique has demonstrated a high potential for wafer size definition of nanometer as well as micrometer size patterns. During the replication process by NIL, the stiction between the stamp and the polymer is one of major problems. This stiction problem is moi·e important in small sized patterns. An antistiction layer prevents this stiction ana insures a clean demolding process. In this paper, we were using a TCP (transfer coupled plasma) equipment and $C_4F_8$ as a precursor to make a Teflon-like antistiction layer. This antistiction layer was deposited on a 6 inch silicon wafer to have nanometer scale thicknesses. The thickness of deposited antistiction layer was measured by ellipsometry. To optimize the process factor such as table height (TH), substrate temperature (ST), working pressure (WP) and plasma power (PP), we were using a design of experimental (DOE) method. The table of full factorial arrays was set by the 4 factors and 2 levels. Using this table, experiments were organized to achieve 2 responses such as deposition rate and non-uniformity. It was investigated that the main effects and interaction effects between parameters. Deposition rate was in proportion to table height, working pressure and plasma power. Non-uniformity was in proportion to substrate temperature and working pressure. Using a response optimization, we were able to get the optimized deposition condition at desired deposition rate and an experimental deposition rate showed similar results.

• Molecules and Cells
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• v.37 no.3
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• pp.234-240
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• 2014

Cisplatin is one of the most potent chemotherapy agents. However, its use is limited due to its toxicity in normal tissues, including the kidney and ear. In particular, nephrotoxicity induced by cisplatin is closely associated with oxidative stress and inflammation. Heme oxygenase-1(HO-1), the rate-limiting enzyme in the heme metabolism, has been implicated in a various cellular processes, such as inflammatory injury and anti-oxidant/oxidant homeostasis. Capsaicin is reported to have therapeutic potential in cisplatin-induced renal failures. However, the mechanisms underlying its protective effects on cisplatin-induced nephrotoxicity remain largely unknown. Herein, we demonstrated that administration of capsaicin ameliorates cisplatin-induced renal dysfunction by assessing the levels of serum creatinine and blood urea nitrogen (BUN) as well as tissue histology. In addition, capsaicin treatment attenuates the expression of inflammatory mediators and oxidative stress markers for renal damage. We also found that capsaicin induces HO-1 expression in kidney tissues and HK-2 cells. Notably, the protective effects of capsaicin were completely abrogated by treatment with either the HO inhibitor ZnPP IX or HO-1 knockdown in HK-2 cells. These results suggest that capsaicin has protective effects against cisplatin-induced renal dysfunction through induction of HO-1 as well as inhibition oxidative stress and inflammation.

• Bulletin of the Korean Mathematical Society
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• v.30 no.1
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• pp.71-77
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• 1993

Every ring considered in the paper will be assumed to be commutative and have a unit element. An ideal A of a ring R will be called primal if the elements of R which are zero divisors modulo A, form an ideal of R, say pp. If A is a primal ideal of R, P is called the adjoint ideal of A. The adjoint ideal of a primal ideal is prime [2]. The definition of primal ideals may also be formulated as follows: An ideal A of a ring R is primal if in the residue class ring R/A the zero divisors form an ideal of R/A. If Q is a primary idel of a ring R then every zero divisor of R/Q is nilpotent; therefore, Q is a primal ideal of R. That a primal ideal need not be primary, is shown by an example in [2]. Let R[X], and R[[X]] denote the polynomial ring and formal power series ring in an indeterminate X over a ring R, respectively. Let S be a multiplicative system in a ring R and S$^{-1}$ R the quotient ring of R. Let Q be a P-primary ideal of a ring R. Then Q[X] is a P[X]-primary ideal of R[X], and S$^{-1}$ Q is a S$^{-1}$ P-primary ideal of a ring S$^{-1}$ R if S.cap.P=.phi., and Q[[X]] is a P[[X]]-primary ideal of R[[X]] if R is Noetherian [1]. We search for analogous results when primary ideals are replaced with primal ideals. To show an ideal A of a ring R to be primal, it sufficies to show that a-b is a zero divisor modulo A whenever a and b are zero divisors modulo A.

• Journal of Korean Society on Water Environment
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• v.35 no.5
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• pp.409-417
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• 2019

In this study, a $480m^3/day$ pilot device was constructed through laboratory experiments based on the Ministry of Environment manual. The purpose of this study was to analyze the characteristics of CSO treatment and backwashing characteristics by applying the pilot device to the field. The purpose of this study was to acquire the basic data necessary for the design and operation management of the real scale filtration type non-point pollution control system. The filtration was conducted while maintaining the linear velocity of 20m/hour. The CSO treatment efficiencies of the pilot devices were 0.4-76.1%(mean 49.0 %), SS 51.4-91.6%(mean 77.8%), COD 22.2-59.4% (mean 38.3%) and TP 14.5-52.6%(mean 38.1%),respectively. The correlation coefficient between SS and the turbidity of influent water was 0.90, higher than that of CSO. To operate the treatment system effectively, the turbidity can be easily measured in real time as the monitoring item is the most appropriate because SS is the main target substance of the non-point source. As a result of analyzing the adsorbent treatment characteristics of PP filter material applied to this pilot device, the average particle diameter range of influent was $4.6-40.1{\mu}m$(mean $21.2{\mu}m$) and the treated water was $0.9-24.5{\mu}m$(mean $6.4{\mu}m$), respectively. Particles of approximately 10m or less are leached out, and so it is necessary to compensate for the raw water containing micro particulate matter.

• Journal of IKEEE
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• v.25 no.2
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• pp.302-308
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• 2021

A 12-bit 10-MS/s pipeline analog-to-digital converter (ADC) is proposed for image processing applications. The proposed pipeline ADC consists of a sample and hold amplifier, three stages, a 3-bit flash analog-to-digital converter, and a digital error corrector. Each stage is operated by using a 4-bit flash ADC (FADC) and a multiplying digital-to-analog converter (MDAC). The proposed sample and hold amplifier increases the voltage gain using gain boosting for the ADC with high resolution. The proposed pipelined ADC is designed using a 180-nm CMOS process with a supply voltage of 1.8 and it has an effective number of bit (ENOB) of 10.52 bits at sampling rate of 10MS/s for a 1-V_pp differential sinusoidal analog input with frequency of 1 MHz. The measured ENOB is 10.12 bits when the frequency of the sinusoidal analog input signal is a Nyquist frequency of approximately 5 MHz.

• The Korea Journal of Herbology
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• v.27 no.6
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• pp.55-61
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• 2012

Objectives : Allium Hookeri (AH) is a traditional herb to treat inflammatory diseases in India and Myanmar. Recently, AH cultivation was succeeded in South Korea. This study was performed to evaluate the anti-inflammatory effects of Korean AH in RAW264.7 cells, mouse macrophage cell line. Methods : To evaluate the anti-inflammatory effects of root of AH, we prepared the 70% ethanol extract, then we examined the productions of nitrite, and pro-inflammatory cytokines. To examine the nitrite, and cytokines, the RAW264.7 cells were treated with AH, then stimulated with lipopolysaccharide (LPS, 500 ng/ml) for 24 h. Then the cells were harvested for griess assay, ELISA and real-time reverse transcription polymerase chain reaction (RT-PCR). Also to detect the ability of AH to induce heme oxygenase-1 (HO-1), we examined the HO-1 expression using real time RT-PCR and western blot. Furthermore, we examined the mitogen activated-protein kinases (MAPKs) and nuclear factor kappa B (NF-${\kappa}B$) activation to find out the underlying mechanisms. Results : AH ethanol extract significantly inhibited the productions of nitrite and interleukin (IL)-$1{\beta}$. AH treatment increased the HO-1 expression dramatically at 1 h, then peaked at 3 h. When the HO-1 was inhibited by tin (Sn) protoporphryin-IX (SnPP), the anti-inflammatory action of AH was reversed. AH treatment inhibited the activation of p38, but not extracelluar signal-regulated kinase (ERK 1/2) and c-Jun $NH_2$-terminal kinase (JNK) and also the degradation of inhibitory kappa B a (Ik-$B{\alpha}$) in the LPS-stimulated RAW 264.7 cells. Conclusions : These data could suggest that AH exerts anti-inflammatory influences through up-regulation of HO-1 and deactivation of p38.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.475-475
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• 2023

직경 5 mm 이하의 미세플라스틱은 인류 활동에 의해 생산되어 하수처리장 처리수, 우수토구, 도로 분진 등 다양한 경로를 통해 하천에 유입되고 있다. 하천에 유입된 미세플라스틱은 하천흐름을 따라 하류로 이동하여 해양환경에까지 이른다. 미세플라스틱은 수체를 따라 이동할 뿐 아니라 수생생물에 의해 섭식되기도 하여 인체 위해성이 우려되는 상황이다. 특히 서울과 경기도의 주요 상수원인 팔당호는 북한강, 남한강, 경안천이 유입되어 형성되기 때문에 미세플라스틱의 유입에 따른 이송-분산 거동 평가가 중요한 영역이다. 본 연구에서는 준3차원 입자추적기법을 이용한 미세플라스틱 거동해석 모형, MPT-Q3D를 개발하였으며 팔당호 내 미세플라스틱의 거동 특성을 분석하였다. MPT-Q3D 모형은 2차원 흐름해석모형과 연계한 입자의 준3차원 거동해석을 위해 step-by-step computation method를 적용하였으며, 전단류에 의한 입자의 수평거동과 난류확산에 및 침강속도에 의한 연직거동 두 단계 계산과정에 따라 입자의 거동을 해석했다. 전단류는 2차원 흐름해석결과로부터 유속의 연직분포식을 적용하여 생성하였으며, 생성된 전단류에 의해 각 연직층 별 유속이 계산되고 𝚫t 이후 입자의 종, 횡 방향 이동거리를 계산한다. 또한 난류확산에 의한 무작위적 거동 계산을 위해 Gaussian 분포를 따른 난수 생성을 통해 무작위적 거동을 계산했다. 각 연직층에 위치한 미세플라스틱 입자의 종, 횡 방향 거동을 계산한 후 입자의 연직거동을 계산한다. 입자의 연직 위치는 난류확산과 침강속도에 따라 계산되며 침강속도는 미세플라스틱의 밀도 및 직경에 따라 결정된다. 현장 샘플링 결과에 따라 팔당호로 유입되는 미세플라스틱은 폴리스틸렌(PS), 폴리에틸렌(PE), 폴리에스테르(Polyester)가 있으므로, 세 종류의 미세플라스틱을 동시에 주입하여 팔당호 내 거동을 분석했다. 남한강, 북한강, 경안천의 유량 차이로 인해 팔당호로 유입되는 미세플라스틱은 대체로 남한강과 북한강의 흐름특성에 영향을 받았다. 경안천의 경우 유량이 낮아 팔당호로 유입되지 못하고 좌안을 따라 하류로 이동됐다. 남한강과 북한강에서 유입된 미세플라스틱은 주로 팔당호 내 소내섬을 거쳐 팔당댐 쪽으로 이동했다. 또한 팔당댐 인근에서는 PP, PE, Polyester 순으로 많은 양이 유입되는 결과가 나타났다.

• Journal of Ginseng Research
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• v.48 no.5
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• pp.511-519
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• 2024

Background: The cycle of seasonal dormancy of perennating buds is an essential adaptation of perennial plants to unfavorable winter conditions. Plant hormones are key regulators of this critical biological process, which is intricately connected with diverse internal and external factors. Recently, global warming has increased the frequency of aberrant temperature events that negatively affect the dormancy cycle of perennials. Although many studies have been conducted on the perennating organs of Panax ginseng, the molecular aspects of bud dormancy in this species remain largely unknown. Methods: In this study, the molecular physiological responses of three P. ginseng cultivars with different dormancy break phenotypes in the spring were dissected using comparative genome-wide RNA-seq and network analyses. These analyses identified a key role for abscisic acid (ABA) activity in the regulation of bud dormancy. Gene set enrichment analysis revealed that a transcriptional network comprising stress-related hormone responses made a major contribution to the maintenance of dormancy. Results: Increased expression levels of cold response and photosynthesis-related genes were associated with the transition from dormancy to active growth in perennating buds. Finally, the expression patterns of genes encoding ABA transporters, receptors (PYRs/PYLs), PROTEIN PHOSPHATASE 2Cs (PP2Cs), and DELLAs were highly correlated with different dormancy states in three P. ginseng cultivars. Conclusion: This study provides evidence that ABA and stress signaling outputs are intricately connected with a key signaling network to regulate bud dormancy under seasonal conditions in the perennial plant P. ginseng.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.1
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• pp.14-34
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• 2016

Objectives: The objective of this study was to evaluate the effects of cytotoxicity, skin regeneration, anti-wrinkle, whitening and skin moisturizing of Oncheongeum (OCE).Methods: The cytotoxicity of OCE lyophilized aqueous extracts (yield=13.82%) was observed against human normal fibroblast cells and B16/F10 murine melanoma cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium Bromide (MTT) assay, and skin regeneration and anti-wrinkle effects were also evaluated through the assay of collagen type I synthesis compared to the transformation of the growth factor (TGF)-β1, hyaluronidase, collagenase and matrix metalloproteinase (MMP)-1 inhibitory assays compared to oleanolic acid (OA), and elastase inhibitory effects compared to phosphoramidon disodium salt (PP). In addition, OCE’s whitening effects were measured by a tyrosinase inhibitory assay and melanin formation test in B16/F10 murine melanoma cells compared to arbutin, and skin moisturizing effects were observed through a mouse skin water content test, respectively. Results: No OCE treatment-related cytotoxic effects appeared on human normal fibroblasts and B16/F10 murine melanoma cells. OCE concentration-dependently increased the collagen Type I synthesis on human normal fibroblast cells, and also effectively inhibited hyaluronidase, elastase, collagenase and MMP-1 activities. In addition, OCE inhibited melanin production of B16/F10 murine melanoma cells and activity of tyrosinase. And significant and dose-dependent increases of skin water content were detected in OCE-treated mouse skin compared to vehicle control skins. Conclusions: OCE showed favorable and sufficient effects in skin regeneration, anti-wrinkle, whitening and skin moisturizing in this experiment. But more detail mechanisms and studies on the skin protective efficiency of in vivo are needed with the screening of active biological compounds in individual OCE herbs.