• Title/Summary/Keyword: $P2X_2$

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EXISTENCE OF SOLUTIONS FOR FRACTIONAL p&q-KIRCHHOFF SYSTEM IN UNBOUNDED DOMAIN

  • Bao, Jinfeng;Chen, Caisheng
    • Bulletin of the Korean Mathematical Society
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    • v.55 no.5
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    • pp.1441-1462
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    • 2018
  • In this paper, we investigate the fractional p&q-Kirchhoff type system $$\{M_1([u]^p_{s,p})(-{\Delta})^s_pu+V_1(x){\mid}u{\mid}^{p-2}u\\{\hfill{10}}={\ell}k^{-1}F_u(x,\;u,\;v)+{\lambda}{\alpha}(x){\mid}u{\mid}^{m-2}u,\;x{\in}{\Omega}\\M_2([u]^q_{s,q})(-{\Delta})^s_qv+V_2(x){\mid}v{\mid}^{q-2}v\\{\hfill{10}}={\ell}k^{-1}F_v(x,u,v)+{\mu}{\alpha}(x){\mid}v{\mid}^{m-2}v,\;x{\in}{\Omega},\\u=v=0,\;x{\in}{\partial}{\Omega},$$ where ${\Omega}{\subset}{\mathbb{R}}^N$ is an unbounded domain with smooth boundary ${\partial}{\Omega}$, and $0<s<1<p{\leq}q$ and sq < N, ${\lambda},{\mu}>0$, $1<m{\leq}k<p^*_s$, ${\ell}{\in}R$, while $[u]^t_{s,t}$ denotes the Gagliardo semi-norm given in (1.2) below. $V_1(x)$, $V_2(x)$, $a(x):{\mathbb{R}}^N{\rightarrow}(0,\;{\infty})$ are three positive weights, $M_1$, $M_2$ are continuous and positive functions in ${\mathbb{R}}^+$. Using variational methods, we prove existence of infinitely many high-energy solutions for the above system.

Enable Secondary User Spectrum Access in Cooperative Communication Scheme with Rayleigh Fading Channel (레일리 페이딩 채널에서 2차 사용자 스펙트럼 접근이 가능한 협력통신 기법)

  • Kim, Lyum;Kong, Hyung-Yun
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.10 no.5
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    • pp.113-119
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    • 2010
  • In this paper, the considered cognitive radio system has a pair of PT-PR and a pair of ST-SR. In first time slot(1 Phase), PT broadcast signal $x_p$ to PR, ST and SR. Then, each receivers(PR, ST, SR) decode received signal $x_p$. In second time slot(2 Phase), ST combine decoded signal ${x_p}^{\prime}$ and signal $x_s$, and it broadcast combined signal to PR and SR. PR and SR decode combined signal. At this time, PR can achieve diversity gain, due to using MRC, it combine 'received and decoded signal ${x_p}^{\prime}$ at 1 phase' and 'detected signal $x_p$ at 2 phase'. SR use linear combining technique and it can obtain $x_s$.

Establishment of an Assay for P2X7 Receptor-Mediated Cell Death

  • Lee, Song-Yi;Jo, Sooyeon;Lee, Ga Eun;Jeong, Lak Shin;Kim, Yong-Chul;Park, Chul-Seung
    • Molecules and Cells
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    • v.22 no.2
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    • pp.198-202
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    • 2006
  • The $P2X_7$ receptor, an ATP-gated cation channel, induces cell death in immune cells and is involved in neurodegenerative diseases. Although the receptor plays various roles in these diseases, the cellular mechanisms involved are poorly understood and antagonists are limited. Here, the development of a cell-based assay for human $P2X_7$ receptor is reported. We established permanent lines of HEK 293 cells expressing a high level of $hP2X_7$ receptor. Functional activity of the $hP2X_7$ receptor was confirmed by whole-cell patch recording of ATP-induced ion currents. Prolonged exposure to ATP resulted in death of the $hP2X_7$-expressing HEK 293 cells and this cell death could be quantified. Two known $P2X_7$ antagonists, PPADS and KN-62, blocked ATP-induced death in a concentration-dependent manner. Thus, this assay can be used to screen for new antagonists of $hP2X_7$ receptors.

High School Students' Knowledge and Attitude about Smoking according to Their Smoking Status (일 지역 고등학생의 흡연상태에 따른 흡연지식과 흡연태도)

  • Choi, Yeon-Hee;Paek, Kyung-Shin
    • Research in Community and Public Health Nursing
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    • v.15 no.2
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    • pp.277-288
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    • 2004
  • Purpose: This study was to provide basic information for preventing high school students from smoking by examining their actual smoking condition and their knowledge and attitude about smoking. Method: The subjects were 515 students selected from six(6), high schools in Jecheon. Data were collected using a questionnaire from the 1st to the 17th of December 2002. The author prepared the tool by modifying the scale of knowledge and attitude about smoking developed by Moon(2001). Data were analyzed with SPSS/WIN program using frequencies, percentages, $x^2$-test, t-test, ANOVA. Duncan test and Pearson's correlation coefficient. Result: 1. The percentage of ex-smoking students was 29.9% of male students and 18.6% of female ones. The percentage of currently smoking students was 23.9% of male students and 3.0% of female ones. The percentage of non-smoking students was 46.2% of male students and 78.4% of female ones, 2. There were not significant differences in smoking knowledge according to smoking status in male and female students. 3. There were significant differences in smoking attitude according to smoking status in male(F=32.70, p=.000) and female(F=11.15, p=.000) students. 4. In smoking status according to general characteristics, there were significant differences according to the type of school($x^2$=32.93, p=.000), grade($x^2$=11.91, p=.018), educational level of the father($x^2$=30.52, p=.000) and the mother($x^2$=14.23, p=.027), monthly allowance($x^2$=17.19, p=.028), harmony of family members($x^2$=15.23, p=.019), school life($x^2$=26.96, p=.00l) and school record($x^2$=30.24, p=.000). 5. In smoking status according to smoking-related characteristics, there were significant differences according to experience in cigarette purchase($x^2$=150.04. p=.000), experience in errands for cigarette($x^2$=20.00, p=.000), knowledge of cigarette price($x^2$=72.52, p=.000), close friends' smoking($x^2$=107.41. p=.000) and smoking of brothers and sisters($x^2$=16.97, p=.002). 6. There were significant correlation between knowledge and attitude about smoking in the whole students(r=.337. p=.000), ex-smokers(r=.324. p=.000), non-smokers(r=.369. p=.000) but there was not a significant correlation between knowledge and attitude about smoking in current smokers(r=.128. p=.30l). Conclusion: Smoking prevention education should considered students' smoking status. Current smokers need smoking prevention education aiming to change their attitude toward smoking in order for them to reduce smoking and to practice smoking cessation.

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ON SOME p(x)-KIRCHHOFF TYPE EQUATIONS WITH WEIGHTS

  • Chung, Nguyen Thanh
    • Journal of applied mathematics & informatics
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    • v.32 no.1_2
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    • pp.113-128
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    • 2014
  • Consider a class of p(x)-Kirchhoff type equations of the form $$\left\{-M\left({\int}_{\Omega}\;\frac{1}{p(x)}{\mid}{\nabla}u{\mid}^{p(x)}\;dx\right)\;div\;({\mid}{\nabla}u{\mid}^{p(x)-2}{\nabla}u)={\lambda}V(x){\mid}u{\mid}^{q(x)-2}u\;in\;{\Omega},\\u=0\;on\;{\partial}{\Omega},$$ where p(x), $q(x){\in}C({\bar{\Omega}})$ with 1 < $p^-\;:=inf_{\Omega}\;p(x){\leq}p^+\;:=sup_{\Omega}p(x)$ < N, $M:{\mathbb{R}}^+{\rightarrow}{\mathbb{R}}^+$ is a continuous function that may be degenerate at zero, ${\lambda}$ is a positive parameter. Using variational method, we obtain some existence and multiplicity results for such problem in two cases when the weight function V (x) may change sign or not.

Testing for $P(X_{1}\;<\;X_{2})$ in Bivariate Exponential Model with Censored Data (중단자료를 갖는 이변량 지수 모형에서 $P(X_{1}\;<\;X_{2})$에 대한 검정)

  • Park, Jin-Pyo;Cho, Jang-Sik
    • Journal of the Korean Data and Information Science Society
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    • v.8 no.2
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    • pp.143-152
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    • 1997
  • In this paper, we obtain maximum likelihood estimators for $P(X_{1}\;<\;X_{2})$ in the Marshall and Olkin's bivariate exponential model with bivariate censored data. The asymptotic normality of the estimator is derived. Also we propose approximate testing for $P(X_{1}\;<\;X_{2})$ based on the M.L.E. We compare the test powers under vsrious conditions through Monte Carlo simulation.

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Dispersion of SmxCe1-xO2-2/x Nanoparticles which is Synthesized by Hydrothermal Process in Aqueous System (수열합성법으로 합성된 나노 SmxCe1-xO2-2/x 분말의 수계 분산)

  • Bae Dong-Sik;Kim Eun-Jung;Han Kyong-Sop
    • Korean Journal of Materials Research
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    • v.15 no.2
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    • pp.112-114
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    • 2005
  • Dispersion stability of the $Sm_xCe_{1-x}O_{2-2/x}$ nanoparticles, which was produced by hydrothermal process, was studied in aqueous suspension using ESA (Eletrokinetic Sonic Amplitude). The average particle size of the synthesized $Sm_xCe_{1-x}O_{2-2/x}$ at nanoparticles was about $5{\pm}2nm$. The dispersion and rheological behavior of the $Sm_xCe_{1-x}O_{2-2/x}$ nanoparticles aqueous suspension was investigated using $NH_4OH\;and\;HNO_3$ as a disperse agent. The colloidal stability of aqueous suspensions with $Sm_xCe_{1-x}O_{2-2/x}$ nanoparticles at different pH values has been investigated by means of zeta potential, average particle size, and the distribution of synthesized $Sm_xCe_{1-x}O_{2-2/x}$ nanoparticles. The isoelectric point of the $Sm_xCe_{1-x}O_{2-2/x}$ nanoparticles was at pH around 11 and the value of zeta potential was at its maximum near pH 6.5.

Syntheses and Characteristics of R-P Phase $Ln_{1-x}Sr_{2-x}Mn_2O_7$(Ln=La, Pr, Gd, Eu, Er, Nd, Sm) (R-P Phase $Ln_{1-x}Sr_{2-x}Mn_2O_7$(Ln=La, Pr, Gd, Eu, Er, Nd, Sm)의 합성 및 특성연구)

  • 송민석;서상일;이재열
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1999.05a
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    • pp.337-340
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    • 1999
  • Since the first reports of CMR(colossal magnetoresistance) effects in some single crystal R-P Phase Ln$_{1-x}$ Sr$_{2-x}$Mn$_{2}$O$_{7}$ 1996. many researches have been carried out to find optimum compositions and processing conditions in this system. In this study, layered perovskite R-P Phase Ln$_{1-x}$ Sr$_{2-x}$Mn$_{2}$O$_{7}$ (x=0.4, Ln=-La, Eu, Gd, Nd, Pr, Sm) phases were synthesized by solid state reaction and their structures were refined by Rietveld method. Electrical and magnetic properties were measured drown to 20K and compare with those of R-P Phase Ln$_{1-x}$ Sr$_{2-x}$Mn$_{2}$O$_{7}$ Phases.es.es.es.es.es.

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Analysis of Toxicity in Escherichia coli from the Expression of Human Purinergic Receptor $P2X_4$ (인간 퓨린수용체 $P2X_4$를 발현시킬 때 나타나는 대장균 독성의 원인분석)

  • Yu, Yon-Joo;Jung, Yun-A;Lim, Dong-Bin
    • Korean Journal of Microbiology
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    • v.47 no.1
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    • pp.7-13
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    • 2011
  • In general, expression of membrane protein in Escherichia coli is very toxic to the host organism, but the mechanism for the toxicity is not clear yet. Expression of human purinergic receptor $P2X_4$ was found to be extremely toxic to the host E. coli. We examined this toxicity by isolation and analysis of less toxic mutant proteins. We could isolate 30 less toxic mutants of $P2X_4$ after hydroxylamine mutagenesis. Western blot showed that all of them produced proteins smaller than the wild type $P2X_4$. DNA sequencing of two largest mutant proteins showed that they were lost its second transmembrane domain. Localization analysis of these mutant proteins showed that they are not in cytoplasmic membrane, but in inclusion bodies. These data showed that inactive truncated $P2X_4$ is not toxic to E. coli and membrane integration and functionality of $P2X_4$ may be needed to show host toxicity.

A Cross-sectional Survey on Drug Abuse among High School Students in Taegu City (대구시내 고등학생의 약물남용에 관한 연구)

  • Lee, Hyun-Sook;Kim, Chung-Nam;Oh, Yun-Jung
    • Research in Community and Public Health Nursing
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    • v.8 no.2
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    • pp.347-367
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    • 1997
  • The purpose of this study was to investigate drug abuse and to find related factors among high school students. The subjects for this study were 973 students from 10 high schools in Taegu city. The data were collected from September 30, 1996 to October 30, 1996. The questionnaire developed by Kim Soyoaja (1991) surveyed adolescent drug use and questions on smoking and drinking were readjusted and added by the researcher based on review. The data was analyzed using frequency, percentage, $X^2-test$, t -test, Pearson Correlation Coefficient with the SPSS /PC+. The results of this study were summarized as follows: 1. The proportion of students who drank alcohol 1-2 times or more per year was 52.4% and smoked Cigarette 1 -2 times or more per year was 20.8%. The 7 different drugs(Analgetics 5.7%. sleeping pills and sedatives 4.2%, antihistamines 1.1%. stimulants 7.7%, hallucinogens 0.8%, inhalants 3.3%, and narcotics 0.6%) were also evaluated. 2. There was a significant relationship between drinking and type of school($X^2$=62.97, p<.0l), grades($X^2$=33.86, P<.001), school life($X^2$= 19.04, p<.001), and delinquent friends($X^2$= 64.72, P<.001). 3. There was a significant relationship between smoking and type of school($X^2$=153.65, p<.001), grades ($X^2$=67.53, p<.001), their respect for teachers ($X^2$=33.80, p<.001) school life($X^2$ =50.87, p<.001), and delinquent friends($X^2$ =85.28, p<.001). 4. There was a significant relationship between the 7 different kinds of drug abuse and type of school ($X^2$=14.65, p<.01), grades($X^2$=12.89, p<.01), their respect for teachers ($X^2$=8.46, p<.05), and delinquent friends($X^2$=22.42, p<.001). 5. There was a significant relationship between a parent's habitual drug abuse and the 7 different kinds of drug abuse($X^2$=7.78, p<.01), as well as a parent's attitude toward drugs and the 7 different kinds of drug abuse($X^2$=6.33, p<.05). 6. There was a significant difference between drinking(t=-12.53, p<.001), smoking(t=-15.98, p<.001), the 7 different kinds of drug abuse(t=-5.77, p<.001), and the respondant's delinquent experience. 7. There was a correlation between drinking and smoking(r=.4166, p<.001), drinking and the 7 different kinds of drug abuse(r=.2200, p<.001), smoking and the 7 different kinds of drug abuse(r=.1428, p<.05). There was a correlation between drinking and smoking(r=.5977, p<.001), drinking and the 7 different kinds of drug abuse(r=.2849, p<. 001), smoking and the 7 different kinds of drug abuse(r=.1711, p<.05) among male students. There was a correlation between drinking and smoking(r=.4219, p<.001), drinking and the 7 different kinds of drug abuse(r=.2611, p<.001), smoking and the 7 different kinds of drug abuse(r=.1764, p<.001) among female students. 8. There was a correlation between drinking and family stability(r=.0709, p<.05) drinkry and parent -child relationships (r=.1321, p<.01), drinking and mother's rearing attitude(r=.0704, P<.05), smoking and parent -child relationships(r=.0813, P<.05). There was a correlation between drinking and family stability(r=.14S7, p<.01), drinkng and parent-child relationships(r=.2147, p<.001), smoking and family stability(r=.1544, p<.01), smoking and parent. -child relationships (r=. 2018, P<.01) among male students. There was a correlation between drinking and family stability(r=.1l21, p<.05), drinking and mother's rearing attitude (r=.0988, P<.05), smoking and parent -child relationships (r=. 0940, P<.05) among female students. 9. There was a significant difference between the 7 different kinds of drug abuse and family stability (t=2.23, p<.05), parent-child relationships (t=4. 34, p<.001), satisfaction with family (t=4.02, p<.001), father's rearing attitude(t=3.04, p<.01), mother's rearing attitude(t=2.87, p<.01). The distribution channel of drugs including alcohol beverages and cigarettes should be evaluated and restructured to discourage student's temptation and to limit accessibility. The step by step preventive teaching on alcohol drinking and cigarette smoking is needed from middle school to help prevent further drug abuse.

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