• Journal of Chest Surgery
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• v.21 no.5
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• pp.828-841
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• 1988

To predict the postoperative hemodynamic status of right ventricle preoperatively, a retrospective analysis was undertaken to determine the influence of pulmonary artery size on postoperative right ventricular pressure in 32 consecutive patients with tetralogy of Fallot who underwent total correction between July, 1987 to June, 1988 at the Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital. We have related the ratio of the postrepair peak systolic pressure in the right ventricle and the systemic systolic arterial pressure[PRV/Ao] to the preoperative cineangiographic measurement of pulmonary arterial tree, expressed as pulmonary artery index[PAI], the ratio of diameter of the right pulmonary artery to diameter of ascending aorta[r.PA/A.Ao], the ratio of right and left pulmonary artery to diameter of descending aorta[r.I.PA/D.Ao] There was tendency that the postrepair PRV/Ao seems to be related to the preoperative diameter of right and left pulmonary artery, but there were no statistically significant correlation with PAI, r.PA/A.Ao, r.l.PA/D. Ao to the ratio of the postoperative peak systolic right ventricular pressure and systemic systolic arterial pressure[PRV/Ao]. There was tendency to decrease the postoperative right ventricular pressure[PRV/Ao] about 11.2%[P < 0.025] within several hours than immediately after repair, but after then, there was no change of right ventricular pressure[PRV/Ao] significantly. There was good correlation of pressure change between the immediate and late postrepair right ventricular pressure[48 hour], and the derived linear regression line was; y=0.68534 0.1994[r=0.57294, P < 0.001]. There was no operative death due to residual high right ventricular pressure[PRV/Ao >0.75] related to hypoplastic pulmonary arterial development, thus we expect, for symptomatic patients even infants, that complete repair can be attempted when the pulmonary artery index[PAI] is over 108mm2/BSA, RPA/AAo is over 0.35, RPA LPA/D. Ao is over 1.36.

• International Journal of Vascular Biomedical Engineering
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• v.2 no.1
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• pp.11-16
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• 2004

Both flow visualizations and computational fluid dynamics were performed to determine hemodynamics in a total cavopulmonary connection (TCPC) model for surgically correcting congenital heart defects. From magnetic resonance images, an anatomically correct glass model was fabricated to visualize steady flow. The total flow rates were 4, 6 and 8L/min and flow rates from SVC and IVC were 40:60. The flow split ratio between LPA and RPA was varied by 70:30, 60:40 and 50:50. A pressure-based finite-volume software was used to solve steady flow dynamics in TCPC models. Results showed that superior vena cava(SVC) and inferior vena cava(IVC) flow merged directly to the intra-atrial conduit, creating two large vortices. Significant swirl motions were observed in the intra-atrial conduit and pulmonary arteries. Flow collision or swirling flow resulted in energy loss in TCPC models. In addition, a large intra-atrial channel or a sharp bend in TCPC geometries could influence on energy losses. Energy conservation was efficient when flow rates in pulmonary branches were balanced. In order to increase energy efficiency in Fontan operations, it is necessary to remove a flow collision in the intra-atrial channel and a sharp bend in the pulmonary bifurcation.

• Membrane Journal
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• v.11 no.3
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• pp.124-132
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• 2001

Silica membranes were prepared on a porous ${\alpha}$-alumina tube with pore size of 150nm by sol-gel and chemical vapor deposition(CVD) method for hydrogen separation at high temperatures. Silica and ${\gamma}$-lumina membranes formed by the sol-gel method possessed a large amount of mesopores of a Knudsen diffusion regime. In order to improve the $H_2$ selectivity, silica was deposited in the sol-gel derived silica/${\gamma}$-alumina layer by thermal decomposition of tetraethyl orthosilicate(TEOS) at $600^{\circ}C$. The CVD with forced cross flow through the porous wall of the support was very effective in plugging mesopores that were left unplugged in the membranes. The CVD modified silica/alumina composite membrane completely rejected nitrogen permeation and thus showed a high $H_2$ selectivity by molecular sieve effect. the permeation of hydrogen was explained by activated diffusion and the activation energy was 9.52kJ/mol.

• Journal of Radiation Industry
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• v.10 no.1
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• pp.7-12
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• 2016

Ikaros, a transcription factor containing zinc-finger motif, has known as a critical regulator of hematopoiesis in immune system. Ikaros protein modulates the transcription of target genes via binding to the regulatory elements of the genes promoters. However the regulatory function of Ikaros in other organelle except nuclear remains to be determined. This study explored radiation-induced modulatory function of Ikaros in cytoplasm. The results showed that Ikaros protein lost its DNA binding ability after LDIR (low-dose ionizing radiation) exposure. Cell fractionation and Western blot analysis showed that Ikaros protein was translocated into cytoplasm from nuclear by LDIR. This was confirmed by immunofluorescence assay. We identified Autotaxin as a novel protein which potentially interacts with Ikaros through in vitro protein-binding screening. Co-immunoprecipitation assay revealed that Ikaros and Autotaxin are able to bind each other. Autotaxin is a crucial enzyme generating lysophosphatidic acid (LPA), a phospholipid mediator, which has potential regulatory effects on immune cell growth and motility. Our results indicate that LDIR potentially regulates immune system via protein-protein interaction of Ikaros and Autotaxin.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.3
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• pp.237-254
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• 2021

Objectives: This study aims to classify the latent profiles in the exposure to hazard factors of salaried employees and test the determinants. Methods: Latent profile analysis(LPA) was conducted using data from the fifth Korean Working Conditions Survey(KWCS). 30,050 of salaried employees were the subjects of this study. After classifying the employees, multinomial logistic regression was used to test the determinants. Results: Salaried employees were classified with three latent profiles based on the exposure to the hazard factors. Employees included in class 1(32.8%) tend to experience low level of physical hazard factors, moderate level of psychological hazard factors, and high level of office work hazard factors. Employees included in class 2(61.8%) tend to be exposed to the moderate to high level of physical hazard factors, moderate to low level of psychological hazard factors, and low level of office work hazard factors. Employees included in class 3(5.4%) tend to experience high level of psychological and physical hazard factors, and moderate level of office work hazard factors. After classification, the demographic, health-, and employment-related variables were tested. Conclusions: This study clarified the features of each class, and proved that employees in class 3 are quite hazardous in that they are exposed to physical and psychological hazard factors much more frequently than other employees. Thus, this study can be used in predicting the high-risk employees and taking preemptive measures for preventing industrial accidents.

• The Journal of the Korea Contents Association
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• v.21 no.7
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• pp.533-545
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• 2021

This study aimed to examine the differences in gender equality consciousness between latent profiles based on corporate workers' organizational culture types. To achieve the study's purpose, descriptive statistics, correlation analysis, and latent profile analysis (LPA) were conducted using 253 Korean corporate workers' data. As a result of the analysis, the latent profiles of organizational culture recognized by corporate workers were classified into 5 profiles. We named each profile as high compete-low create culture, high compete-low collaborate culture, collaborate culture, high create culture, and high control culture based on each profile's organizational culture perception. The ANOVA test found statistically significant differences between the groups in the gender equality consciousness. This study is meaningful in that it reveals the relationship between the organization culture perception and the gender equality consciousness and suggested implications for the organizational-level intervention to improve the gender equality consciousness. It will provide basic data for your research.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.1
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• pp.37-53
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• 2021

The purpose of this study is to analyze the types of latent profiles depending on the job satisfaction of youth entrepreneurs in South Korea and examine the influence of related variables. Latent profile analysis (LPA) was conducted using data from the 12th year of the Youth Panel Study. Results of the study revealed that there were five latent profiles based on job satisfaction among young entrepreneurs: lowest job satisfaction, mid-low job satisfaction, middle job satisfaction, mid-high job satisfaction, and highest job satisfaction. By applying multinomial logistic analysis, the influencing factors for each latent profiles have been derived. Gender, marital status, subjective health, self-esteem, entrepreneurial motivation, difficulty in start-up, person-job fit, intrinsic or extrinsic job values, business scale, income, work hour, education or training, and labor insurance were significant predictors of youth entrepreneurs' job satisfaction. Based on these results, the article discusses practical implications that can enhance the job satisfaction of young entrepreneurs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.41-50
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• 2020

The purpose of this study was to identify latent classes in school readiness which were measured by both parents and teachers, and to test the relationship with school adaption, academic abilities, problematic behaviors, self-esteem, and happiness. Latent Profile Analysis (LPA), MANOVA, and one-way ANOVA were conducted using the data of 1,154 1st to 3rd grade elementary school students, and the data was collected between the 7th year (2014) to the 10th year (2017) from the Korean Children and Youth Panel Study. The results of study were as follows. First, four school readiness groups were identified: the consistent low group, parent perceived high group, the teacher perceived high group, the consistent high group. Second, the consistent high group and the teacher perceived high group showed relatively better academic abilities and school adaption than the consistent low group. Furthermore, the consistent high group showed higher academic abilities, self-esteem, and happiness, but lower problematic behaviors than the consistent low group. The findings of this study could be utilized as preliminary data for understanding school readiness to promote successful school adaption and psychological well-being of children.

• Journal of the Korea Society of Computer and Information
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• v.28 no.3
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• pp.137-148
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• 2023

The purpose of this study is to classify the potential types of mental health of mothers of multicultural youth by applying Latent Profile Analysis, analyze the influence of predictors, and find out how differences in potential types affect parental efficacy. To this end, panel data for the 9th year (2019) of the Multicultural Youth Panel Survey (MAPS) were used. As a result of the analysis, first, the mental health types of mothers of multicultural adolescents were analyzed in the order of 'middle risk type of mental health'(class3) > 'high risk type of self-esteem'(class1) > 'high risk type of mental health'(class4) > 'cultural adaptation and daily life stress'(class2). Second, compared to the "class 1" group, the lower the family economy level of multicultural youth mothers, the lower the educational background of multicultural youth fathers (husbands) graduate from middle school, the lower the level of Korean, and the lower the level of communication with children, the higher the odds of belonging to the 'mental health medium risk' group (Ods). Third, compared to the 'middle risk type of mental health'(class3) and 'high risk type of mental health'(class4), the 'high risk type of self-esteem'(class1) group was found to have a significant positive (+) effect on parental efficacy.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.1
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• pp.24-36
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• 2003

The digital mobile communication will be developed till getting multimedia service in anyone, any where, any time. Theses requiring items are going to be come true via IMT-2000 system. Transmitting signal bandwidth of IMT-2000 system is 3 times as large as IS-95 system. That is mean peak to average of signal is higher than IS-95A system. So we have to design it carefully not to effect in adjacent channel. HPA(High Power Amplifier) located in the end point of system is operated in 1-㏈ compression point(Pl㏈), then it generates 3rd and 5th inter modulation signals. Theses signals affect at adjacent channel and RF signal is distorted by compressed signal which is operated near by Pl㏈ point. Then the most important design factor is how we make HPA having high linearity. Feedback, Pre-distorter and Feed-forward methods are presented to solve theses problems. Feed-forward of these methods is having excellent improving capacity, but composed with complex structure. Generally, Linearity and Efficiency in power amplifier operate in the contrary, then it is difficult for us to find optimal operating point. In this paper we applied algorithm which searches optimal point of linear characteristics, which is key in Power Amplifier, using minimum current point of error amplifier in 1st loop. And we made 2nd loop compose with new structure. We confirmed fabricated LPA is operated by having high linearity and minimum current condition with ACPR of -26 ㏈m max. @ 30㎑ BW in 3.515㎒ and ACLR of 48 ㏈c max@${\pm}$㎒ from 1W to 40W.