• 제목/요약/키워드: $II_1$ factors

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수리구조물의 파괴위험도와 설계홍수량에 관한 수문학적 연구(II) - 비연초과치 계열을 중심으로 - (Hydrological Studies on the design flood and risk of failure of the Hydraulic Structures( II))

  • 이순혁;박명근
    • 한국농공학회지
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    • 제28권3호
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    • pp.69-78
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    • 1986
  • This studies were established to find out the characteristics of frequency distributiom for the number of occurrence and magnitude, probable flood flows according to the return periods, design floods, and design frequency factors for the studying basins in relation to the risk levels which can be correlated with design return period and the life of structure in the non-annual exceedance series. Eight watersheds along Han, Geum, Nak Dong and Seom Jin river basin were selected as studying basins. The results were analyzed and summarized as follows. 1. Poisson distribution and Exponential distribution were tested as a good fitted distributions for the number of occurrence and magnitude for exceedance event, respectively,at selected watersheds along Han, Geum, Nak Dong and Seom Jin river basin. 2.Formulas for the probable flood flows and probable flood flows according to the return periods were derivated for the exponential distribution at the selected watersheds along Han, Geum, Nak Dong, and Seom Jin river basin. 3.Analysis for the risk of failure was connected return period with design life of structure in the non-annual exceedance series. 4.Empirical formulas for the design frequency factors were derivated from under the condition of the return periods identify with the life of structure in relation to the different risk levels in the non-annual exceedance series. 5.Design freguency factors were appeared to be increased in proportion to the return periods while those are in inverse proportion to the levels of the risk of failure. Numerical values for the design frequency factors for the non-annual exceedance series ware appeared generally higher than those of annual maximum series already published by the first report. 6. Design floods according to the different risk levels could be derivated by using of formulas of the design frequency factors for all studying watersheds in the nor-annual exceedance series.

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Streptomyces coelicolor A3(2)에서 hrdA유사 Sigma 인자 유전자의 클로닝 (Cloning of hadA-like Sigma Factor Gene from Streptomyces coelicolor A3(2))

  • 한지숙;조은정;노정혜
    • 미생물학회지
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    • 제32권4호
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    • pp.264-270
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    • 1994
  • 세균의 RNA 중합효소에서 여러 ${\sigma}$ 인자들 간에 보존된 아미노산 서열중 2.3 부위와 4.2 부위의 아미노산 서열로부터 유 n하여 두가지의 PCR primer를 제작하였다. 이들을 이용하여 PCR을 수행하였을 때, E. coli와 Streptomyces coelicolor의 DNA로부터 예상되었던 480 bp 정도의 DNA가 증폭되는 것을 관찰하였다. E. coli DNA에서 증폭된 DNA를 클로닝하여 염기서열을 결정한 결과 E. coli의 rpoS 유전자로부터 유래하였음을 알았다. 이를 탐침으로 S. coelicolor에서 genomic DNA hybridization을 수행하였을 때, PvuII 절편 두가지 (3.5 kb, 2.0 kb) 와 SalI 절편 두가지(3.4kb, 1.5 kb)에 탐침이 결합하는 것을 관찰하였다. 3.5 kb의 pvuII 절편을 sublibrary로부터 클로닝하고, 탐침이 결합하는 1.0kb의 BamHI/HincII 절편의 염기서열을 분석하였다. 부분적으로 결정된 염기서열을 BLAST 프로그램을 이용하여 GenBank와 EMBL, PDB 등의 data library의 유전자들과 비교하여 본 결과Streptomyces속의 ${\sigma}$인자들을 비롯한 Synechococcus종, Anabaena종, Pseudomonas aeruginosa, Stigmatella aurantica 등의 주된 ${\sigma}$ 인자와 높은 유사성을 보였다. 현재까지 1.2 부위와 4 부위에 해당하는 부분의 염기서열을 결정하였는데, 이 부분은 S. coelicolor에서 알려진 다섯가지의 ${\sigma}$ 인자 유전자 중 hrdA와 가장 높은 유사성을 보이며, 아미노산의 유사성이 1.2부위에서는 88%, 4 부위에서는 75%인 것으로 나타났다.

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한국, 일본, 독일, 미국의 CAD교육 현황과 성공요인 비교(제2보) (A Comparative Analysis of CAD Education and Key Success Factors in Korea, Japan, Germany and USA (Part II))

  • 이윤정
    • 한국의류학회지
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    • 제29권1호
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    • pp.46-57
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    • 2005
  • This empirical research aims to identify and compare key success factors in Computer Aided Design (CAD) education in Korea, Japan, Germany and USA. Employing a couple of statistical methods (multiple regression and factor analysis) on survey data, it was found that the decisive factors in the CAD education differed among four countries. Generally speaking, however, educational methods are less important than educational conditions, of which professors and educational environment are dominant factors. This implies that the so called constructivistic way of teaching/learning is not so effective as expected. In order to improve educational performance in Korea, as far as CAD education is concerned, professors need to enhance relationship with industry and universities to support more hardware and software.

의복선택기준에 관한 측정지개발의 기초 연구(II) (A Study on Develop An Instrument to Measure the Criteria on Clothing Selection)

  • 박은주
    • 대한가정학회지
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    • 제25권4호
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    • pp.33-45
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    • 1987
  • The purpose of this study is to analyze the factorial structure of the criteria on clothing selection of the working women, and then to provide the date to develop an instrument to measure the criteria on clothing selection. A total of 877 samples were selected from unmarried female in the twenties. Data were analyzed using factor analysis, Pearson's product-mement correlation coefficients, content analysis and Cronbach's α. The results of the study were as follows; 1. There were identified 7 factors as the clothing selection criteria of the working women; Fashion, Practicality, Modesty, Appearance, Service, Comfort, and Impulse purchase. 2. Comparing with the previous results, we confirmed that the criteria on clothing selection was made up of at least 8 factors; Practicality, Comfort, Brand or price, Impulse purchase, Fashion, Individuality, Modesty, and Service. 3. According to the correlation among 8 factors, they formed two clusters; one cluster contained Practicality, Comfort, and Modesty factor, and the other did Brand or price, Impulse purchase, Fashion and Individuality factor. 4. Service factor was significantly correlated to the other factors, that is, service was the very important criteria on the clothing selection.

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전주한옥마을에 대한 인식이 한정식 레스토랑 이용만족에 미치는 영향 연구 (A Study on the Influence of Recognition for Jeonju Hanok Village on the Image of Traditional Cultures and Satisfaction with Traditional Korean Restaurants)

  • 민계홍
    • 한국조리학회지
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    • 제19권5호
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    • pp.36-48
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    • 2013
  • 본 연구의 목적은 전주 한옥마을에 대한 인식이 전통문화이미지와 한정식 레스토랑 이용만족도에 미치는 영향을 알아보고자 한다. 조사 기간은 2013년 6월 1일부터 6월 16일까지 한옥마을에 있는 한정식 레스토랑을 이용한 경험이 있는 전주시민을 제외한 사람을 대상으로 설문조사를 실시하였다. 분석결과 내용을 요약하면 다음과 같다. 첫째, 한옥마을에 대한 인식 요인은 3개요인으로 음식 요인, 한국미 요인, 역사성 요인으로 명명하였으며, 이미지에 대한 요인은 2개의 요인으로 전통이미지 요인, 문화이미지 요인으로 명명하여 가설 설정 후 검증을 하였다. 가설 I의 "한옥마을에 대한 인식은 전통이미지에 영향을 미칠 것이다"에서는 한옥마을에 대한 인식은 전통미 요인이 전통이미지에 가장 큰 영향을 미치고 있다는 것으로 나타나서 가설 I은 채택이 되었다. 둘째, 가설II의 "한옥마을에 대한 인식은 문화이미지에 영향을 미칠 것이다"에서는 음식 요인이 가장 영향력을 미치는 것으로 나타나서 가설 II는 채택이 되었다. 셋째, 가설 III의 "전통이미지와 문화이미지는 한정식 레스토랑 이용만족도에 영향을 미칠 것이다" 분석 결과, 전통미 요인이 가장 영향력을 미치는 것으로 나타나서 가설 III은 채택이 되었다. 향후 연구에서는 업종별로 레스토랑 만족도 연구가 다양한 연구방법에 의해서 활발하게 진행이 되어야 하며, 한정식 레스토랑 만족을 위해서 한옥마을 이미지 관리를 위한 노력이 필요하겠다.

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제2기 위암에서 3 Subgroup간의 비교 분석 (Comparative Analysis of Three Subgroups in Stage II Stomach Cancer)

  • 서병선;김병식;김용호;육정환;오성태;김완수;박건춘
    • Journal of Gastric Cancer
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    • 제1권1호
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    • pp.32-37
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    • 2001
  • Purpose: Three subgroups of stage II stomach cancer (T1N2M0, T2N1M0, T3N0M0) by UICC-TNM staging system show obvious survival difference to each other, which becomes the pitfall of the current staging system. We analyzed the survival and relapse pattern of stage II stomach cancer patients in three subgroups retrospectively to prove the need for change in staging system. Materials and Methods: From July 1989 to December 1995, curative gastric resection was performed in 1,037 patients with gastric adenocarcinoma, and among them 268 patients ($26\%$) were in stage II. The number in each of subgroups (T1N2M0, T2N1M0, and T3N0M0) were 17, 139 and 112 respectively. Survival and relapse pattern were analyzed and median follow up period was 46 months. Results: The 3-year cumulative survival rates of T1N2M0, T2N1M0, and T3N0M0 were $50\%,\;80\%,\;and\;76\%$ respectively (p=0.001). And the 3-year cumulative survival rates of T1N2M0 was comparable to those of 2 subgroups of stage IIIa (T2N2M0, T3N1M0), $47\%\;and\;45\%$ (p>0.05). Peritoneal recurrence was the most frequent in T3N0M0. And hematogenous spread was more frequent in T2N1M0 while nodal spread was more frequent in T1N2M0. Ten out of 17 cases of T1N2M0 died of recurrence. Most of them showed submucosal tumor with depressed lesion and mean tumor size was 3.3 cm. Conclusions: Up-staging of T1N2M0 should be considered because it has the lowest survival rate and the worst prognosis among the three subgroups of Stage II stomach cancer patients. In early gastric cancer patients with high-risk factors (large tumor size, invasion into the submucosal layer, and lymphatic vessel involvement), lymph node dissection and postoperative adjuvant therapy is recommended in an attempt to prevent recurrence in the form of lymph node metastasis.

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Gonadotropin-releasing Hormone and Its Receptor as a Therapeutic Concept in the Progression of Epithelial Ovarian Cancer

  • Kim, Ki-Yon;Choi, Kyung-Chul
    • 한국수정란이식학회지
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    • 제24권1호
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    • pp.1-14
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    • 2009
  • Ovarian cancer is a significant cause of cancer-related death in women, but the main biological causes remain open questions. Hormonal factors have been considered to be an important determinant causing ovarian cancer. Recent studies have shown that gonadotropin-releasing hormone (GnRH)-I and its analogs have clinically therapeutic value in the treatment of ovarian cancer. In addition, numerous studies have shown that the potential of GnRH-II in normal reproductive system or reproductive disorder. GnRH-I receptors have been detected in approximately 80% of ovarian cancer biopsy specimens as well as normal ovarian epithelial cells and immortalized ovarian surface epithelium cells. GnRH-II receptors have also been found to be more widely expressed than GnRH-I receptors in mammals, suggesting that GnRH receptors may have additional functions in reproductive system including ovarian cancer. The signal transduction pathway following the binding of GnRH to GnRH receptor has been extensively studied. The activation of protein kinase A/C (PKA/PKC) pathway is involved in the GnRH-I induced anti-proliferative effect in ovarian cancer cells. In addition, GnRH-I induced mitogen-activated protein kinase (MAPK) activation plays a role in anti-proliferative effect and apoptosis in ovarian cancer cells and the activation of transcriptional factors related to cellular responses. However, the role of GnRH-I and II receptors, there are discrepancies between previous reports. In this review, the role of GnRH in ovarian cancer and the mechanisms to induce anti-proliferation were evaluated.

AE-MDB시험 시 인체모형 상해치에 대한 시험 인자 영향성 연구 (The Study on influence of test factors for WorldSID injury through AE-MDB side crash test)

  • 선홍열;한표경;오은경;윤일성
    • 자동차안전학회지
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    • 제7권1호
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    • pp.7-12
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    • 2015
  • NCAP(New Car Assessment Program) makes vehicle manufacturer improve safety performance through free competition and customers guarantee vehicle selection by providing information of vehicle safety. That's why it is important not only to meet the regulation, but also to cope with NCAP. EuroNCAP(European New Car Assessment Program) side tests have conducted by using Progressive MDB and Euro SID II in order to reproduce crash test between two vehicles over 10 years. However various researches report that Progressive MDB and Euro SID II do not reflect evolving vehicle design, impact performance and biofidelity of human. Therefore EuroNCAP has the plan to conduct AE-MDB side crash test using WorldSID which is more evolved from 2015 by replacing Progressive MDB and EuroSID II. Automobile manufacturers need to develop safety performance for new test closely. This paper is to find test set-up parameters which affect into dummy injury instead of restraint system and to research on its tendency. It is processed with mini and small car to know influence as changing vehicle size and also analyzed by DFSS(Design for six sigma) which is one of optimization tools. DFSS is vaildated by simulating CAE with L18 orthogonal array of 6 control factors adjustable as EuroNCAP requirement.

II급 부정교합 치료 후 재발과 골격치성요소의 상관성 (Correlationship of skeletodental factors to a relapse in class II correctionn)

  • 정애진;이도훈;강경화;김상철
    • 대한치과교정학회지
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    • 제34권2호
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    • pp.153-163
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    • 2004
  • II급 부정교합 치료 후 일어나는 재발에 영향을 미치는 요소를 알아보기 위하여 치료 후 결과가 안정하게 유지된 군과 재발이 일어난 군으로 구분하여 골격 및 치성요소를 비교하였다. 치료 전과 치료 후 측모 두부방사선사진을 이용하여 t-test와 상관분석을 시행한 결과 다음과 같은 결론을 얻었다. 1. 안정군과 재발군 간에 치료 전 골격 및 치성 관계는 대체로 차이가 없었다. 2. 안정군에서 하악골의 전방성장이 더 많이 일어났다. 3. 안정군에서의 하악 전치는 더 직립되었으며 상악전치는 설측 경사가 적은 경향을 보였다. 4. 재발군에서 교합평면이 전하방으로 경사되는 경향을 보였다.

산림환경 및 하천형태인자에 의한 유역안정성 평가 (Evaluation of Watershed Stability by the Forest Environmental and Stream Morphological Factors)

  • 정원옥;마호섭
    • 한국환경복원기술학회지
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    • 제4권4호
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    • pp.1-11
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    • 2001
  • This study was carried out to analyze the characteristics of forest environmental and stream morphological factors by using the quantification theory(I) for evaluation of the watershed stability. Present annual mean sediment yield of erosion control dams were investigated in 167 sites of erosion control dam constructed during 1986 to 1999 in Gyeongbuk. The results obtained from this study were summarized as follows; According to the coefficients of partial correlation, each factor affecting to sediment was shown in order of gravel contents, number of first streams order, number of total streams, length of total streams, forest type, length of main stream, parent rock, stand age, soil texture, stream order, slope gradient, soil depth and aspect. Descriptions of class I were as follow; Igneous rock of parent rock, hardwood stands of forest type, less than 20 year of stand age, less than 30cm of soil depth, sandy clay loam of soil texture, more than 41% of gravel contents, south~east of aspect, 2,501~3,500m of length of main stream, 21~25 of number of total streams, 5,501~10,000m of length of total streams, 3 or more than 4 of stream order, more than 16 of number of first stream orders and more than $31^{\circ}$ of slope gradient. Descriptions of class II were as follow; Metamorphic rock of parent rock, coniferous stands of forest type, more than 25 year of stand age, 31~40cm of soil depth, silt loam of soil texture, 11~20% of gravel contents, north~west of aspect, 2,501~3,500m of length of main stream, 16~20 of number of total streams, 3,501~5,500m of length of total streams, 3 of stream order, 11~15 of number of first stream orders and more than $31^{\circ}$ of slope gradient. Descriptions of class III were as follow; Sedimentary rock of parent rock, mixed stands of forest type, more than 25 year of stand age, more than 51cm of soil depth, silty clay loam of soil texture, less than 10% of gravel contents, south~west of aspect, less than 500m of length of main stream, less than 5 of number of total streams, less than 1,000m of length of total streams, less than 1 of stream order, less than 2 of number of first stream orders and less than $25^{\circ}$ of slope gradient. The prediction method of suitable site for erosion control dam divided into class I, II, and III for the convenience of use. The score of class I evaluated as a very unstable area was more than 8.4494. A score of class II was 8.4493 to 6.0452, it was evaluated as a moderate stable area, and class III was less than 6.0541, it was evaluated as a very stable area.

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