• Title/Summary/Keyword: $HgC_2$

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The Arterial Blood Pressure Response to the Stimulation of Peripheral Afferent Nerves in Cats (말초감각신경 자극이 동맥혈압변화에 미치는 영향에 관한 연구)

  • Lim, Seung-Pyung;Kim, Jun;Kim, Chong-Whan
    • Journal of Chest Surgery
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    • v.20 no.3
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    • pp.439-450
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    • 1987
  • The arterial blood pressure response elicited by stimulating the peripheral afferent fibers of different groups and origins was studied in cats. Experimental animals were anesthetized with a-chloralose [60mg/kg] and artificially ventilated with a respirator. The lumbosacral spinal cord was exposed through a laminectomy and L7 ventral root was isolated. The sural, medial gastrocnemius and common peroneal nerves were also exposed in the hindlimb. The arterial blood pressure was monitored continuously while the exposed peripheral nerves and L7 ventral root were being stimulated. Then, spinal lesions were made on the dorsolateral sulcus area, dorsolateral funiculus and other areas at the thoracolumbar junction. The arterial blood pressure responses were compared before and after making spinal lesions. The following results were obtained. 1. The mean arterial blood pressure was elevated from 103*7.3 to 129*8, 1 [mean*S.E.] mmHg [p<0.001] during stimulation of the sural nerve with C-strength [1000T], 20Hz. Stimulation with Ad-strength, 1Hz resulted in the depression of the arterial pressure by 8 mmHg [p<0.01]. 2. Stimulation of the medial gastrocnemius nerve with Ad-strength did not elicit any significant change in arterial blood pressure. Stimulation with C-strength, 20 Hz induced a pressor response from 102*6.2 to 117*6.4 mmHg [p<0.01] while that with C-strength, 1Hz induced a depressor response from 104*6.1 to 93*4.9 mmHg [p<0.001]. 3. A pressor response by 56 [from 107*7 5 to 163*9.4] mmHg [p<0.001] was induced during stimulation of the common peroneal nerve with C-strength, 20Hz stimuli. Stimulation with A4-strength, 1Hz depressed the arterial blood pressure from 111~9.3 to 94*7.8 mmHg [P<0.005]. The activation of the ventral root afferent fibers with C-strength, 20 Hz stimuli induced a pressor response by 22 mmHg [from 115*9.4 to 137*8.6 mmHg] [p<0.001]. 4. The pressor response elicited during stimulation of the sural nerve was abolished by making lesions on the dorsolateral sulcus area bilaterally. With the medial gastrocnemius nerve, the pressor response had not been abolished completely by the dorsolateral sulcus lesions. The pressor response disappeared completely with addition of the bilateral dorsolateral funiculus lesions. 5. The depressor response induced by stimulation of the sciatic nerve with Ad-strength, 1Hz was decreased by making lesions on the dorsolateral funiculus. 6. From the above results it is concluded that the difference in the blood pressure responses to the activation of the muscular afferent and the cutaneous afferent fibers is responsible for the groups of afferent fibers and the spinal ascending pathways.

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Combined Toxicity in the Brackish Water Flea Diaphanosoma celebensis Exposed to Benzo[a]pyrene and Mercury (벤조피렌과 수은에 대한 기수산 물벼룩 Diaphanosoma celebensis의 복합 독성 영향)

  • Yoo, Je-Won;Cho, Hayoung;Jeong, Jeon Min;Lee, Young-Mi
    • Journal of Marine Life Science
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    • v.4 no.2
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    • pp.45-52
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    • 2019
  • Polycyclic aromatic hydrocarbons (PAHs) are persistent and commonly detected in marine ecosystem. They coexist with a various contaminants including heavy metals in real environment, but most studies have been still focused on single effects of these contaminants to aquatic organisms. In this study, the single and combined effects of benzy[a]pyrene (B[a]P) and HgCl2 were investigated in the brackish water flea, Diaphanosoma celebensis. For combined effect study, three mixtures A (3:7), B (5:5), and C (7:3) of benzy[a]pyrene (B[a]P) and HgCl2 were determined by 48 h - LC50 values of single exposure. Combined effects of both chemicals were estimated by concentration addition (CA) model and independent action (IA) model. As results, 48 h - LC50 values of benzy[a]pyrene (B[a]P) and HgCl2 was 25.75 ㎍ l-1 and 3.6 ㎍ l-1, respectively. TU values of mixture A, B, and C were 1.06, 0.83, and 0.96, respectively, indicating additive effects of mixtures using CA model. This study will be helpful as basic data for understanding the combined effects of contaminants in marine environment.

Enhancement of a Liver Form of Cytosolic Phospholipase $A_2$ Activity by Methylmercury

  • Huh, Don-Haeng;Kang, Mi-Sun;Sohn, Dong-Hun;Na, Doe-Sun;Kim, Dae-Kyong
    • BMB Reports
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    • v.31 no.2
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    • pp.189-195
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    • 1998
  • Methylmercury (MeHg), which is widely distributed in the environment, is well known for both its acute and chronic poisoning effects on the human health; however, the precise biochemical mechanisms by which this compound elicits its toxicity in a cellular level are still poorly understood. To examine whether MeHg-induced liver injury involves activation of Phospholipase $A_2$ ($PLA_2$), the $PLA_2$ activity of control and MeHg-administrated livers was measured. MeHg stably enhanced a liver form of cytosolic $PLA_2$ activity, which exhibited several biochemical properties similar to those of the 100 kDa $cPLA_2$, except in its elution profile of a DEAE-5PW HPLC, and it migrated as a molecular weight of 80 kDa in Western blot analysis. This blotting analysis also indicated that the MeHg-induced enhancement of the activity could be due to the increase in the amount of the enzyme protein rather than a stable modification of the enzyme such as phosphorylation. Our data also showed the higher myeloperoxidase activity in MeHg-administrated liver than in the control, suggesting that this increase in the amounts of the 80 kDa $PLA_2$ and its activity may be resulted from infiltration of neutrophils into the liver during a hepatic injury process such as MeHg-induced inflammation. Taken together, these data suggest that MeHg-induced liver injury may be mediated by activation of the 80 kDa form of liver cytosolic $PLA_2$.

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Influence of Growth Conditions on the Structural and Atomic Fractional Properties of $Hg_{1-x}Cd_xTe$ Films Electrodeposited onto Titanium and ITO glass (티타늄과 ITO유리기판에 전착법으로 성장된 $Hg_{1-x}Cd_xTe$ 박막과 성장 조건이 결정구조 및 성분 조성비에 미치는 영향)

  • Choi, C.T.
    • Journal of Sensor Science and Technology
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    • v.10 no.1
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    • pp.80-85
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    • 2001
  • $Hg_{1-x}Cd_xTe$(MCT) thin films were grown onto ITO glass and titanium plate by stationary cathodic electrodeposition in aqueous solution contained $CdSO_4$, $TeO_2$, and $HgCl_2$. During deposition two main fabrication parameters were taken into account deposition potential and growth temperature. MCT films deposited by varying two parameters were studied by X-ray diffraction, electron probe micro analyser(EPMA) and scanning electron microscope measurements. It was shown by XRD and EPMA measurements that the structure of MCT films was zinc blonde and the composition of MCT films can be controlled with the deposition potential.

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TEM Study on the HgCdTe/Anodic oxide/ZnS Interfaces (투과전자현미경에 의한 HgCdTe/양극산화막/ZnS 계면 특성에 관한 연구)

  • 정진원;김재묵;왕진석
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.32A no.9
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    • pp.121-127
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    • 1995
  • We have analyzed the double insulating layer consisting of anodic oxide and ZnS through TEM experiments. The use of double insulating layer for HgCdTe surface passivation is one of the promising passivation method which has been recently studied deeply and the double insulating layer is formed by the evaporation of ZnS on the top of anodic oxide layer grown in H$_{2}$O$_{2}$ electrolyte. The structure of anodic oxide layer on HgCdTe is amorphous but the structure of oxide layer after the evaporation of ZnS has been changed to micro-crystalline. The interface layer of 150.angs. thickness has been found between ZnS and anodic oxide layer and is estimated to be ZnO layer. The results of analysis on the chemical components of ZnS, the interface layer and anodic oxide layer have showed that Zn has diffused into the anodic oxide layer deeply while Hg has been significantly decreased from HgCdTe bulk to the top of oxide layer. The formation of ZnO interface layer and the change of structure of anodic oxide layer after the evaporation of ZnS are estimated to be defects or to induce the defects which might possibly affect the increase of the positive fixed charges shown in C-V measurements of HgCdTe MIS.

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A Study on the Nonstoichiometry of the Iron Oxide System (산화철계의 비화학양론에 관한 연구)

  • Choi, Jae-Shi;Yo, Chul-Hyun;Choi, Sung-Nack
    • Journal of the Korean Chemical Society
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    • v.17 no.5
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    • pp.337-345
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    • 1973
  • The nonstoichiometry of the iron oxide system has been studied by analyzing the weight loss of a sample, measured by using a quartz microbalance, in a temperature range from $0^{\circ}C$ to $1200^{\circ}C$ under oxygen pressures from $10^{2}mmHg$ to $10^{-4}mmHg$. The Y values of the formula, $FeO_{1+\gamma}$, that have been obtained by this means for various conditions of temperature and pressure in this range are considered to be more accurate than values obtained by methods requiring thste quenching of the sample before measurements are made. The plots of log Y vs $log PO_2$ (or $log Y =_n log PO_2$) show linearity and n calculated from the slope of the plot is about 1/10 at $1000^{\circ}C$, indicating a difference between the nonstoichiometric and oxidation mechanisms. The condition for the formation of stoichiometric FeO was determined to be $1200^{\circ}C$ under $10^{-3}mmHg$ of $O_2$ and the composition of the oxide under standard conditions was $FeO_{1.11185}$. As in general more oxygen dissolves into the oxide system at lower temperatures and higher oxygen pressures, the deviation from stoichiometric FeO is greater under those conditions. A comparison of the change in conductivity of the sample indicates that full phase transition does not take place with conductivity transition.

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Transglycosylation Reaction on Cellobiose by Dextansucrase of Leuconostoc mesenteroides B512FMC/6HG8 (Leuconostoc mesenteroides B512FMC/6HG8가 생산하는 Dextransucrase에 의한 Cellobiose의 당전이반응)

  • 강현록;양지영;이현규
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.5
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    • pp.802-806
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    • 2000
  • The transglycosylation reaction by dextansucrase from Leuconostoc mesenteroides B512FMC/6HG8 was investigate with cellobiose as an acceptor molecule and sucrose as a donor. he optimal conditions of transglycosylation on cellobiose were found that the ration of sucrose to cellobiose was 3:1, the amount of enzyme was 2U/mL, the ionic strength of buffer was 25 mM, pH was 5.0 and reaction temperature was $25^{\circ}C$. also, acceptor products of cellobiose by transglycosylation were a series of oligosaccharides showing the degree of plymenzation of 6.

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The Effect of Fusible Interlining on the Appearance related Properties & Mechanical Characteristics of the Lyocell Fabrics(II) (리오셀직물의 심지접착에 따른 외관적 성능 및 역학적 특성(II))

  • 김인영;오수민;송화순
    • Journal of the Korean Home Economics Association
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    • v.40 no.7
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    • pp.15-24
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    • 2002
  • In this work, the effect of fusible interlining on the appearance related properties and mechanical characteristics of Lyocell fabric after fusing was investigated. Two different types(20's and 10's) of Lyocell face fabric with six different interlining(by thickness and structure) for earth Lyocell fabric were examined. In order to establish the optimum fusing condition for the different face fabric and interlining, peel strength of each fused fabric was measured, which was dependent on the fusing temperature, pressure, and time. The characteristics related appearance and mechanical characteristics of each fused fabric were determined. The results are as follows: The peel strength was excellent, when the fabric was fused with the force of 3kgf/$textrm{cm}^2$ at $120^{\circ}C$ for 15seconds. Flex stiffness, G, 2HG, 2HG5(shear), B, 2HB(bending) of 100% Lyocell fabric 10's were higher than those of 100% Lyocell 20's. Flex stiffness, crease recovery, G, 2HG, B, 2HB of thicker woven interlining were higher than those of thinner woven interlining. Crease recovery of twill interlining were higher than those of plain interlining. In case of shear and bending properties, however, plain interlining was higher than twill interlining. Flex stiffness, crease recovery, G, 2HG, 2HG5, B, 2HB of nonwoven interlining were higher than those of woven interlining. In case of drapability, however, woven interlining was higher than nonwoven interlining.

High Resolution TEM Observations in $Hg_{1-x}\;Tl_{x}\;Ba_{2}(Ca_{0.86}\;Sr_{0.14})_{2}\;Cu_{3}\;O_{8+\delta}$ Superconductors (고온 초전도체 $Hg_{1-x}\;Tl_{x}\;Ba_{2}(Ca_{0.86}\;Sr_{0.14})_{2}\;Cu_{3}\;O_{8+\delta}$의 고분해능 TEM에 의한 구조 관찰)

  • Lee, Hwack-Joo;Ryu, Hyun;Hur, Nam-H.;Park, Yong-K.
    • Applied Microscopy
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    • v.25 no.4
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    • pp.124-131
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    • 1995
  • High resolution transmission electron microscopic observations on the $Hg_{1-x}\;Tl_{x}\;Ba_{2}(Ca_{0.86}\;Sr_{0.14})_{2}\;Cu_{3}\;O_{8+\delta}$(x=0.00, 0.25, 0.50, 0.75) were carried out using side-entry type TEM working at 300 kV. The TEM samples are prepared by powder method. The pellets are crushed in agatar motar and suspended in $CCl_4$, solution and scooped in holely carbon microgrid. The 1223 structures are observed in all samples with [010] zone axis. Except x=0.25 sample, the lattice parameter a and c tend to decrease as the thallium contents are increased ranging from 0.3936 nm to 0.3713 nm for a, and from 1.6131 nm to 1.5138 nm for c parameter. Those of x=0.25 sample are reduced too much, 0.3785 nm for a, 1.5375 nm for c. The sample with x=0.25 shows the intergrowth of 1223 and 1234 structure with the ratio of 19 to 1. As the thallium content increases, the structures become more stable without having any defect. The samples are damaged by electron beam irradiation during the observation, however the structure can endure longer as the thallium contents are increased.

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Cardiorespiratory Regulations in the Japanese Amberjack (Seriola quinqueradiata) Exposed to Acute Hypoxia (저산소환경이 방어(Seriola quinqueradiata) 순환계의 산소운반 기능에 미치는 영향)

  • LEE Kyoung Seon;ISHIMATSU Atsushi;JEON Joong Kyun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.38 no.2
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    • pp.106-111
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    • 2005
  • We studied the cardio-respiratory properties in the Japanese amberjack (Seriola quinqueradiata) during acute hypoxia exposure. Fish were exposed to three levels of hypoxia (80, 60 or 50 mmHg) for 60 min at $25^{\circ}C$. Cardiovascular parameters (cardiac output; Q, heart rate; HR, stroke volume; SV, blood pressure; $P_{DA}$) changed little from pre-exposure values during both 80 and 60 mmHg of hypoxia. During 50 mmHg of hypoxia, the fish showed a bradycardia which significantly affected Q, whereas no change in SV. $P_{DA}$ increased transiently. Arterial oxygen partial pressure ($PaO_2$) immediately reduced along with a decrease of the water oxygen partial pressure ($P_WO_2$). Arterial $O_2$ content ($CaO_2$) decreased significantly only after 60 min of 50 mmHg of hypoxia. Arterial pH (pHa) and hematocrit value (Hct) did not change significantly. Comparing the effects of different levels of hypoxia, oxygen delivery to the tissues ($Q\;{\times}\;CaO_2$) should be maintained a constant over a broad range of $P_WO_2$, however, severely depressed below 50 mmHg of hypoxia.