• Journal of Ginseng Research
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• v.28 no.2
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• pp.111-119
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• 2004

The renoprotective effects of Korean Red Ginseng were examined in STZ-induced diabetic spontaneously hypertensive rats (SHR). After 3 day administration of streptozotocin (STZ), animals were divided into four groups : Group 1, hypertensive rats (H); Group 2, hypertensive rats with diabetes (HD); Group 3, hypertensive rats with diabetes administered with 100 mg/kg of ginseng total saponin(GTS); Group 4, hypertensive rats with diabetes administered with 600 mg/kg of ginseng non-saponin (GNS). After 2 weeks oral administraions of GTS and GNS, body weight, kidney weight, plasma glucose, urinary albumin excretion, serum creatinine, urea nitrogen and blood pressure were examined. After 3,7 and 21 day of STZ administration, expressions of TGF-${\beta}$1 and fibronectin in kidney were analyzed by immunoblotting and/or immunohistochemistry. GTS and GNS treatments slightly decreased blood pressure when compared to H and HD groups. Also, GTS and GNS treatments ameliorated kidney hypertrophy without affecting plasma glucose levels. Meanwhile, GNS treatment increased Cu/Zn-SOD activity in kidney and generally showed more efficient renoprotective effects than GTS. We suggest that the renoprotective effects of ginseng partially result from downregulations of TGF-${\beta}$1, fibronectin expressions and anti-oxidative activity of ginseng non-saponin.

• Food Science and Preservation
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• v.15 no.1
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• pp.161-168
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• 2008

The effects tea beverages (TBs) prepared from powdered green tea (Gt), oolong tea (Ot), black tea (Bt), or pure tea (Pt) with lemon, orange, grenadine etc on cadmium toxicity in rats were investigated Sensory evaluations of the TBs are better than those of each water extracted teas. Cadmium (50 ppm) was administered to experimental rats fed a basic diet, or a diet with various TBs (15% w/v), for 5 weeks. Although body weight gains, feed intakes, and fecal weights in all Cd-treated groups were lower than those in the normal control group (NC), feed efficiency ratio, urine volumes, liver weights, and kidney weights did not differ significantly between groups. The serum ALT and AST levels in the Cd-treated control group (Cd-Co) were higher than those in the NC animals. Serum ALT and AST levels in all Cd-treated rats fed TB-supplemented diets were lower than in animals of the Cd-Co group. Tibia and femur weights in Cd-Co animals were lower than those in NC rats. Tibia and femur weights in Cd-treated rats fed TB-supplemented diets were higher than those in Cd-Co animals. There were no between-group differences in tibia lengths; animals in the NC and TB-supplemented diet groups showed femur lengths longer than those of Cd-Co rats. Although the contents of crude ash and cadmium in the femurs of Cd-Co mts was markedly higher than in the femurs of NC animals, the cadmium content in femurs of Cd-Co rats was significantly lower than that in the femurs of NC animals. The changes in mineral levels caused by Cd administration were alleviated by every TB-supplemented diet tested Whereas fecal calcium excretion by Cd-Co animals was significantly higher than that of NC rats, calcium excretion by Cd-treated rats fed TB-supplemented diets was significantly lower than that of Cd-Co animals. Fecal cadmium excretion by all Cd-treated rats fed TB-supplemented diets was significantly higher than that of Cd-Co animals. In conclusion, this study provides experimental evidence that various TBs may regulate cadmium-induced organ toxicity by reducing cadmium accumulation in tissues through the mechanism of increasing the fecal excretion of cadmium.

• Restorative Dentistry and Endodontics
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• v.27 no.5
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• pp.535-542
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• 2002

The purpose of this study was to evaluate the effect of EDTA irrigant according to application time and temperature. 31 human mature extracted teeth with a single canal were sectioned with microtome in 3mm thickness and gained 62 samples of root canals. They were distributed randomly into 6 groups of 10 specimens each and control group of 2 specimens. Each specimen was prepared with GT rotary file (Dentsply, Maillefer Co., Swiss) and irrigated with 3 ml sodium hypochlorite every minute. Then smear layer was removed with EDTA solution (PULPDENT$^{\circledR}$, PULPDENT Co., USA.) except two control specimens. Specimens of each group were irrigated with 17% EDTA. The time and temperature of application were as follows : (Table omitted) All specimens were split longitudinally and prepared for examination by scanning electron microscopy. A set of reference micrographs was used to award a debris score as follows: 0 = no smear layer, all tubules clean and open; 1 = no superficial smear layer, tubule openings visible, but some contain debris plug or soft tissue remnants: 2 = moderate smear layer, some tubules open and others closed; 3 = heavy smear layer, most/all tubule openings obscured. Results were evaluated with Kruskal-Wallis test to determine whether there was statistically significant difference among six groups. Pairs of groups were analyzed using the Student-Newman-Keuls Method and Mann-Whitney test. The results were as follows : 1. Control specimens showed heavy smear layer at the canal walls 2. Among the groups applied with EDTA for 2 minutes, group 1 showed the heaviest smear layer, and there was statistically significant difference between group 1 and the other groups(p<0.05). 3. Among the groups applied with EDTA for 5 minutes, group 4 and group 6 showed smear layer but there was no significant difference between them. 4. Among the groups applied with EDTA for the same temperature, group 1 showed heavier smear layer than group 4, and there was statistically significant difference(p<0.05). 5. Among the groups applied with EDTA for the same temperature, group 2 showed heavier smear layer than group 5 and group 3 showed heavier smear layer than group 6. But there was no statistically significant difference among them. From the results above, it could be concluded, EDTA solution is effective in removing of smear layer when it is applied for 5 minutes. If EDTA is applied for 2 minutes, it should be applied above room temperature.

• Journal of Preventive Medicine and Public Health
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• v.29 no.1 s.52
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• pp.43-50
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• 1996

We experienced a case of nephropathy in chronic lead poisoning. The patient was 43-year-old male who has been working in secondary lead smelting plant for 14 years. On admission, blood pressure was 160/90 mmHg and the others were non-specific. In past history, he received chelating agent administration for lead poisoning irregularly and medicated for gout, and the blood lead concentration was $180.0{\mu}g/dl$ on 2 months before admission. Smoking habit has been 1 pack per day for 15 years and drinking habit has been 1 bottle of Soju per day but less flow. In liver function test, AST/ALT were 27/28 IU/l and $\gamma-GT$ was 456 IU/l. In blood test, Hb : 11.5 g/dl, Hct : 34.0% and basophilic stipplings were found in peripheral blood smear. Chest PA was normal and abdominal ultrasonographic finding was non-specific except fatty liver. In the test of lead exposure indices, $PbB:83.0{\mu}g/dl,\;PbU:28.3{\mu}g/l$, and blood ZPP was $300.0{\mu}g/dl$. And in renal function test, BUN : 31.4 mg/dl, blood creatinine : 2.7mg/dl, blood uric acid. 9.1 mg/dl, urinary albumin : 100.0 mg/g creatinine, urinary $\alpha_1-microglobulin$ : 120.5 mg/g creatinine, urinary $\beta_2-microglobulin$ : $183.8{\mu}g/g$ creatinine, and 24 hours urinary creatinine clearance was 31.9 ml/min. The ultrasonoguided renal biopsy showed the global sclerosis of glomerulus, moderate atrophy and loss of tubule, and interstitial fibrosis in light microscopy. There were diffuse losses of brush border of proximal tubule in electronmicroscopy.

• Korean journal of applied entomology
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• v.47 no.4
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• pp.395-400
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• 2008

Economic injury levels (EILs) and economic threshold (ET) were estimated for the two spider mite, Tetranychus urticae Koch (Acari, Tetranychidae) on greenhouse eggplants. T. urticae density increased until the mid-July and thereafter decreased in all plots where initial density of the mite were different each 0, 2, 5, 10 and 20 adults per plant was innoculated on June 7. Growth variables of were not different among experimental plots but fruit weights were lower in plots with higher initial mite density than in plots with lower initial mite density. Total number of fruits and the number of marketable fruits decreased in plots with higher initial mite density. The rates of yield loss increased with increasing initial mite density, resulting in 0, 3.9, 11.3, 14.5, 22.8% reduction in each of the above plots, respectively. The relationship between initial T. urticae densities and yield losses was well described by a linear regression, Y = 1.085X + 2.474, $R^2$ = 0.9659. Based on the relationship, the number of adults per plant which can cause 5% loss of yield was estimated to be approximately 1.8.

• Korean Journal of Poultry Science
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• v.31 no.4
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• pp.255-263
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• 2004

Two experiments were conducted to evaluate the feeding values of sesame oil meal (SOM) and to investigate the effects of its dietary supplementation on egg production in laying hens. In experiment I, the values of true metabolizable energy (TME), nitrogen corrected true metabolizable energy (TMEn) and true amino acid availability (TAAA) were determined by force-feeding 16 ISA-Brown roosters and collecting the total excreta from the birds, The TME and TMEn of SOM were 2.30 and 1.99 kcal/g, respectively, and the average TAAA of 15 amino acids was $76.93\%$. In experiment 2, a total of ninety, 48 weeks old ISA-Brown layer were randomly divided into 9 groups of 10 birds each and assigned to three experimental diets containing 0, 5 and $10\%$ SOM for 4 weeks (30 birds per treatment). The inclusion of SOM into laying hen diets at the 5 and $10\%$ level did not affect production and quality of egg. The C18:3 $\omega$3 content of egg yolks in the $10\%$ SOM group was higher than the other groups, but not significantly. There were no adverse effects on blood parameters in layers fed treated diets containing $5\%$ or $10\%$ SOM, The results indicate that SOM can be used for layers diet up to $10\%$ without any significant negative effects on egg production and quality.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3923-3930
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• 2014

In this study, the physical and dynamic characteristics of soil were analyzed by selecting 3 sections as research subjects among road and structure construction sections in the construction site of the Gwangyang ${\bigcirc}{\bigcirc}$ industry area, and conducted consolidation analysis and bearing capacity assessments through Midas-GTS according to the construction conditions of the structures and section conditions of reinforcement using stabilized soil. The effects of improving the settlement and bearing capacity according to the improved effects of the stability and sections of reinforcement using stabilized soil in applying the reinforcement method using stabilized soil were analyzed as a solution for improving the settlement and bearing capacity of soft clay for constructing roads and structures. The improvement effects of the settlement and bearing capacity were outstanding when the reinforcement method using stabilized soil to the soft clay was applied. After applying the reinforcement method using stabilized soil, the holdback effect of the consolidation settlement was excellent by decreasing the volume of the consolidation settlement from a minimum of 53% to a maximum of 82%. When the width of the reinforcement using stabilized soil was twice the width of the constructed structure, it was found that the holdback effect of the consolidation settlement ranged from 1% to 7% through the width of reinforcement using stabilized soil. In addition, when applying reinforcement more than 6m in width and 1m in depth using stabilized soil, it was found that the increase in the allowable bearing capacity was 2.3 to 3.3 times more than that before applying the reinforcement, which suggests that the increase in bearing capacity by applying the reinforcement method using stabilized soil was significant.

• Industry Promotion Research
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• v.3 no.2
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• pp.33-40
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• 2018

The purpose of this study is to analyze the effect of flexible working system for work - family connection on job satisfaction. A total of 73 questionnaires were analyzed for workers. The results of this study are as follows: First, flexible work system for work and home affairs has a statistically insignificant relationship with job satisfaction, flexible work system, work satisfaction, work status, flexible work system, organizational satisfaction, But the correlation between job satisfaction and organizational satisfaction showed a low correlation of .313, p <.01. Second, according to the regression analysis on the job satisfaction of the flexible work system, it was analyzed that the flexible work system for work and home affair did not have a statistically significant effect on the job satisfaction. Third, there was a significant relationship between the number of employees and average years of service. The average number of years of service was below 5 years. No child (38.4%), 1 person (15.1%), 2 children (11% ). & Lt; / RTI & gt; The purpose of this study is to examine the effect of the flexible work system on the job satisfaction of the worker and the family, and to verify the effectiveness of the flexible work system by increasing the flexible work system and the job satisfaction by activating the flexible work system.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.1
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• pp.132-139
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• 2004

This study was peformed in order to compare general components, color, free amino acid, fatty acid and organic acid contents between commercial doenjang (C-1, C-2, C-3) and green tea doenjang (GT). The moisture content in green tea doenjang was higher than that in commercial doenjang, but the contents of crude protein, carbohydrate and energy in commercial doenjang were higher than those in green tea doenjang. The crude lipid and fiber contents of commercial doenjang were similar to green tea doenjang. Catechin content of green tea doenjang was 2.3%. The total content of free amino acids in commercial doenjang ranged from 2,739∼6,380 mg% in which it showed wide variation among samples and the total content of free amino acids in green tea doenjang was 3000 mg%. Glutamic acid was almost high in commercial doenjang except one product but green tea doenjang was low. Linoleic acid (51%) was the highest content among the fatty acids. The major organic acid in both commercial and green tea doenjang was oxalic acid and its content in commercial times higher than in green tea doenjang. The antioxidant activity of green tea doenjang was higher than that of commercial doenjang.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.33 no.3
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• pp.250-256
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• 2000

The purpose of this study was to investigate the adsorption kinetics of heavy metals (Cu, Cd and Pb) using three tidal flat sediments and two yellow loesses. The relationship between adsorption rate calculated by non-linear regression model and chemical parameters was estimated. The contents of ignitiot loss (I.L.) am Fe, Mn and Al oxides of yellow loess were higher $1.5{\~}6 times$ than those of tidal flat sediments. But the contents of silt and clay of tidal flat sediment in Eueunri was higher than others. Heavy metals adsorption were occured rapidly in the intial 30 min and the concentration of adsorbed heavy metals were $4.1{\~}14.7\;{\mu}g/g\;for\;Cu,\;2.8{\~}16.7\;{\mu}g/g\;for\;Cd\;and\;43.4{\~}101.7\;{\mu}g/g$ for Pb, showing a high cumulative adsorption of $8{\~}70{\%}\;for\;Cu,\;18{\~}31{\%}\;for\;Cd and\;19{\~}52{\%}$ for Pb after 3hr. In initial concentration of $0.5{\times}10^(-5)M$, adsorption rate of heavy metals by the tidal flat sediments and yellow loesses was the sequence Pb>Cu^gt;Cd. The adsorption kinetics of Cu, Cd and Pb was found to be one-site kinetic model. Especially, in the case of Cu, there was a high negative ($R^2= -0.88{\~}-0.99$) linear correlation between chemical parameter such as I.L., Al oxide, silt and clay, and adsorption rate coefficients ($K_a$) calculated by non-linear model.