• 제목/요약/키워드: $G^E$ models

검색결과 664건 처리시간 0.028초

Dimensionality Reduction of RNA-Seq Data

  • Al-Turaiki, Isra
    • International Journal of Computer Science & Network Security
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    • 제21권3호
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    • pp.31-36
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    • 2021
  • RNA sequencing (RNA-Seq) is a technology that facilitates transcriptome analysis using next-generation sequencing (NSG) tools. Information on the quantity and sequences of RNA is vital to relate our genomes to functional protein expression. RNA-Seq data are characterized as being high-dimensional in that the number of variables (i.e., transcripts) far exceeds the number of observations (e.g., experiments). Given the wide range of dimensionality reduction techniques, it is not clear which is best for RNA-Seq data analysis. In this paper, we study the effect of three dimensionality reduction techniques to improve the classification of the RNA-Seq dataset. In particular, we use PCA, SVD, and SOM to obtain a reduced feature space. We built nine classification models for a cancer dataset and compared their performance. Our experimental results indicate that better classification performance is obtained with PCA and SOM. Overall, the combinations PCA+KNN, SOM+RF, and SOM+KNN produce preferred results.

벽식 아파트 구조에서 연결부재의 거동특성을 고려한 비선형 동적 응답 (Nonlinear Dynamic Response of Well-Slab Apartment Building Considering The Behavior of Coupling Elements)

  • 김기현;장극관;서대원;천영수
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2002년도 봄 학술발표회 논문집
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    • pp.437-442
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    • 2002
  • The purpose of this study is to investigate nonlinear behavior and estimate ultimate resistance of the wall structure against seismic loading. Experimental data for RC coupling elements are used for specifying the strength deterioration and stiffness degradation factor of hysteretic model. Modified coupling element models are used in the push over analysis and time history analysis. In the time history analysis, three earthquake waves are used in the analysis and their peak ground accelerations are changed to be 0.2g. The conclusions of this study are as follows : (1) In the push over analysis, yielding of coupling elements occurred at lower story with small story drift ratio as 0.3%. (2) In the time history analysis, the story drift ratio is sufficient for the requirement of Korean Code, But coupling elements at most stories of the buildings occurred yielding. i. e. the earthquake resistant capacity of shear wall structures is not sufficient at 0.2g.

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Modeling and Analysis of Warranty Cost for 2D-Policies Associated with Sale of Second-hand Products

  • Chattopadhyay G.;Yun Won-Young
    • International Journal of Reliability and Applications
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    • 제7권1호
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    • pp.71-77
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    • 2006
  • The market for second hand products has been growing for a variety of reasons (e.g., new products appearing at a faster rate and the expected life of products increasing due to rapid advances in technology). The demand for warranties for second-hand products has been growing along with the growth of the market for second-hand products. Warranty for new products (consumer durables, industrial and commercial, and specialized defense products) has received a lot of attention. In contrast, warranties for second-hand product have received very little attention. Often, dealers of second-hand product such as cars offer 2D-warranties (Year and Kilometers). The expected warranty cost associated with a second-hand product for 2D-Policies is a function of the age of the item and its usage (as it affects failures over the warranty period), the warranty terms and the servicing strategy used by the dealer. This paper deals with development of models for warranty cost analysis along with the decision on sale price and warranty cover for 2D-Warranty policies associated with sale of second-hand products.

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TPLS 혈액주머니 내의 3차원 비정상유동에 대한 수치해석 연구: 액추에이터 속도의 영향 (Numerical Study of 3D Unsteady Flow in a Blood Sac of TPLS: Effect of Actuator Speed)

  • 정기석;성현찬;박명수;고형종;심은보;민병구;박찬영
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2003년도 추계 학술대회논문집
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    • pp.206-211
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    • 2003
  • This paper reports the numerical results for blood flow of the sac squeezed by moving actuator in the TPLS(Twin Pulse Life Support System). Blood flow in the sac is assumed to be 3-dimensional unsteady newtonian fluid. where the blood flow interacts with the sac, which is activated by the moving actuator. The flow field is simulated numerically by using the FEM code, ADINA. It is well known that hemolysis is closely related to shear stress acted on blood flow. According to this fact, we simulate four models with different speed for moving actuator and examine the distribution of shear stress for each model. Numerical results show that maximum shear stress is strongly dependent on the actuator speed.

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Lateral-torsional seismic behaviour of plan unsymmetric buildings

  • Tamizharasi, G.;Prasad, A. Meher;Murty, C.V.R.
    • Earthquakes and Structures
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    • 제20권3호
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    • pp.239-260
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    • 2021
  • Torsional response of buildings is attributed to poor structural configurations in plan, which arises due to two factors - torsional eccentricity and torsional flexibility. Usually, building codes address effects due to the former. This study examines both of these effects. Buildings with torsional eccentricity (e.g., those with large eccentricity) and with torsional flexibility (those with torsional mode as a fundamental mode) demand large deformations of vertical elements resisting lateral loads, especially those along the building perimeter in plan. Lateral-torsional responses are studied of unsymmetrical buildings through elastic and inelastic analyses using idealised single-storey building models (with two degrees of freedom). Displacement demands on vertical elements distributed in plan are non-uniform and sensitive to characteristics of both structure and earthquake ground motion. Limits are proposed to mitigate lateral-torsional effects, which guides in proportioning vertical elements and restricts amplification of lateral displacement in them and to avoid torsional mode as the first mode. Nonlinear static and dynamic analyses of multi-storey buildings are used to validate the limits proposed.

딥러닝 기반 광학 문자 인식 기술 동향 (Recent Trends in Deep Learning-Based Optical Character Recognition)

  • 민기현;이아람;김거식;김정은;강현서;이길행
    • 전자통신동향분석
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    • 제37권5호
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    • pp.22-32
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    • 2022
  • Optical character recognition is a primary technology required in different fields, including digitizing archival documents, industrial automation, automatic driving, video analytics, medicine, and financial institution, among others. It was created in 1928 using pattern matching, but with the advent of artificial intelligence, it has since evolved into a high-performance character recognition technology. Recently, methods for detecting curved text and characters existing in a complicated background are being studied. Additionally, deep learning models are being developed in a way to recognize texts in various orientations and resolutions, perspective distortion, illumination reflection and partially occluded text, complex font characters, and special characters and artistic text among others. This report reviews the recent deep learning-based text detection and recognition methods and their various applications.

Sub-grid study of scaling effects to evapotranspiration of heterogeneous forest landscape at the Volga source area in Russia

  • Oltchev, A.;G.Gravenhorst;A.P.Tishenko;Joo, Y.T.
    • 한국농림기상학회:학술대회논문집
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    • 한국농림기상학회 2001년도 춘계 학술발표논문집
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    • pp.151-152
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    • 2001
  • A common problem of the model simulations of the land surface - atmosphere interaction is to choose the appropriate spatial scale and resolution at which the simulations are to be performed. The accuracy of energy and water exchange predictions between the land surface and the atmosphere in regional and global scale atmospheric models is mainly influenced by: model simplifications applied to describe the spatial heterogeneity of land surface properties within individual grid cells; ignoring the variability of sub-grid properties (e.g. relief, vegetation, soils), and; lacks of necessary input meteorological and biophysical data.(omitted)

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G894T and 4a/b Polymorphisms of NOS3 Gene are Not Associated with Cancer Risk: a Meta-analysis

  • Haque, Shafiul;Mandal, Raju K;Akhter, Naseem;Panda, Aditya K;Hussain, Arif;Khan, Saif;Lohani, Mohtashim
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권7호
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    • pp.2929-2937
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    • 2015
  • Endothelial nitric oxide synthase (eNOS or NOS3) produces nitric oxide and genetic polymorphisms of NOS3 gene play significant roles in various processes of carcinogenesis. The results from published studies on the association between NOS3 G894T and NOS3 intron 4 (4a/b) polymorphisms and cancer risk are conflicting and inconclusive. However, i n order to assess this relationship more precisely, a meta-analysis was performed with PubMed (Medline), EMBASE and Google web searches until February 2014 to select all published case-control and cohort studies. Genotype distribution data were collected to calculate the pooled odd ratios (ORs) and 95% confidence intervals (CIs) to evaluate the strength of association. A total of 10,546 cancer cases and 10,550 controls were included from twenty four case-control studies for the NOS3 G894T polymorphism. The results indicated no significant association with cancer risk as observed in allelic (T vs G: OR=1.024, 95%CI=0.954 to 1.099, p=0.508), homozygous (TT vs GG: OR=1.137, 95%CI=0.944 to 1.370, p=0.176), heterozygous (GT vs GG: OR=0.993, 95%CI=0.932 to 1.059, p=0.835), recessive (TT vs GG+GT: OR=1.100, 95%CI=0.936 to 1.293, p=0.249) and dominant (TT+GT vs GG: OR=1.012, 95%CI=0.927 to 1.105, p=0.789) genetic models. Similarly, a total of 3,449 cancer cases and 3,691 controls were recruited from fourteen case-control studies for NOS3 4a/b polymorphism. Pooled results indicated no significant association under allelic (A vs B: OR=0.981, 95%CI=0.725 to 1.329, p=0.902), homozygous (AA vs BB: OR=1.166, 95%CI=0.524 to 2.593, p=0.707), heterozygous (BA vs BB: OR=1.129, 95%CI=0.896 to 1.422, p=0.305), dominant (AA+BA vs BB: OR=1.046, 95%CI=0.779 to 1.405, p=0.763) and recessive (AA vs BB+BA: OR=1.196, 95%CI=0.587 to 2.439, p=0.622) genetic contrast models. This meta-analysis suggests that G894T and 4a/b polymorphisms of NOS3 gene are not associated with increased or decreased risk of overall cancer.

후방연장 가철성 국소의치에서 임플란트의 길이와 위치가 응력분산에 미치는 영향 (Influence of the length and location of implants on distal extension removable partial dentures: finite element analysis)

  • 김진희;조진현;이청희
    • 구강회복응용과학지
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    • 제31권3호
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    • pp.186-194
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    • 2015
  • 목적: 임플란트 위치와 길이가 하악 후방연장 가철성 국소의치(DERPD)와 연관된 임플란트의 응력 분포와 변위에 미치는 영향을 알아보는 것이다. 연구 재료 및 방법: #35, 36, 37이 소실된 시상절단면의 후방연장모형과 가철성 국소의치를 기본모형으로 사용했다. NX 9.0으로 7개의 모델을 디자인했다. 모델 A, B, C에서 각각 11, 6, 4 mm 길이의 임플란트가 #37 인공치 하방에 위치되었다. 모델 D, E, F에서 각각 11, 6, 4 mm의 임플란트가 #36 인공치 하방에 위치되었다. 모델 G는 임플란트가 없었다. 수직하중(250 N)을 #36의 중심와에 가했고, 유한요소 분석프로그램을 이용해 von Mises stress와 변위를 관찰했다. 결과: #37에 위치한 임플란트는 #36에 위치한 것과 비교시 주변골에 더 낮은 응력집중도를, #36에 위치한 임플란트는 #37에 위치한 것보다 더 적은 변위를 보였다. 결론: 임플란트 지지형 가철성 국소의치에서 후방부에 위치한 임플란트는 전방부에서보다 더 이점을 가지며, 길이가 더 긴 임플란트의 사용은 응력분산을 위해서 중요하다.

Water consumption prediction based on machine learning methods and public data

  • Kesornsit, Witwisit;Sirisathitkul, Yaowarat
    • Advances in Computational Design
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    • 제7권2호
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    • pp.113-128
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    • 2022
  • Water consumption is strongly affected by numerous factors, such as population, climatic, geographic, and socio-economic factors. Therefore, the implementation of a reliable predictive model of water consumption pattern is challenging task. This study investigates the performance of predictive models based on multi-layer perceptron (MLP), multiple linear regression (MLR), and support vector regression (SVR). To understand the significant factors affecting water consumption, the stepwise regression (SW) procedure is used in MLR to obtain suitable variables. Then, this study also implements three predictive models based on these significant variables (e.g., SWMLR, SWMLP, and SWSVR). Annual data of water consumption in Thailand during 2006 - 2015 were compiled and categorized by provinces and distributors. By comparing the predictive performance of models with all variables, the results demonstrate that the MLP models outperformed the MLR and SVR models. As compared to the models with selected variables, the predictive capability of SWMLP was superior to SWMLR and SWSVR. Therefore, the SWMLP still provided satisfactory results with the minimum number of explanatory variables which in turn reduced the computation time and other resources required while performing the predictive task. It can be concluded that the MLP exhibited the best result and can be utilized as a reliable water demand predictive model for both of all variables and selected variables cases. These findings support important implications and serve as a feasible water consumption predictive model and can be used for water resources management to produce sufficient tap water to meet the demand in each province of Thailand.