• Nutrition Research and Practice
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• 제14권2호
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• pp.102-108
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• 2020

BACKGROUND/OBJECTIVES: In Oriental medicine, certain foods may be beneficial or detrimental based on an individual's constitution; however, the scientific basis for this theory is insufficient. The purpose of this study was to investigate the effect of body constitution, based on the Sasang type of Korean traditional medical classification system, on the bioavailability of soy isoflavones of Cheonggukjang, a quick-fermented soybean paste. SUBJECTS/METHODS: A pilot study was conducted on 48 healthy Korean men to evaluate the bioavailability of isoflavone after ingestion of food based on constitution types classified by the Sasang typology. The participants were classified into the Taeeumin (TE; n = 15), Soyangin (SY; n = 15), and Soeumin (SE; n = 18) groups. Each participant ingested 50 g of Cheonggukjang per 60 kg body weight. Thereafter, blood was collected, and the soy isoflavone metabolites were analyzed by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Ntrikinetic analysis of individual isoflavone-derived metabolites was performed. RESULTS: Our nutrikinetic analysis identified 21 metabolites derived from isoflavones in the blood samples from 48 healthy Korean men (age range, 21-29 years). Significant differences were observed in the time to maximum concentration (T_max) and elimination half-life (t_1/2) for nine metabolites among the three groups. The T_max and t_1/2 of the nine metabolites were higher in the SE group than in the other groups. Moreover, the absorption rates, as determined by the area under the plasma-level curve (AUC) values of intact isoflavone, were 5.3 and 9.4 times higher in the TE group than in the SY and SE groups, respectively. Additionally, the highest AUC values for phase I and II metabolites were observed in the TE group. CONCLUSIONS: These findings indicate that isoflavone bioavailability, following Cheonggukjang insgestion, is high in individuals with the TE constitution, and relatively lower in those with the SE and SY constitutions.

• 천문학논총
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• 제22권3호
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• pp.63-73
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• 2007

In this paper, we introduce the performance test results of digital data processing system for KVN (Korean VLBI Network). The digital data processing system for KVN consists of DAS (Data Acquisition System) and high-speed recorder which called Mark5B system. DAS system performs the digitalization of analog radio signal through ADS-1000 gigabit sampler with 1 Gsps/2-bit and process the digital filtering of digital signal. Mark5B system records the output data of DFB (Digital Filter Bank) with about 1 Gbps. In this paper, we carried out the preliminary evaluation experiments of the KVN digital data processing system connected between DAS system and Mark5B with VSI (VLBI Standard Interface) interface which is designed for compatible in each VLBI system. We first performed all of the KVN digital data processing system connected by VSI interface in the world. In factory inspection phase, we found that the DAS system has a memory read/write error in DSM (Digital Spectrometer) by analyzing the recorded data in Mark5B system. We confirmed that the DSM memory error has been correctly solved by comparing DSM results with Mark5B results. The effectiveness of KVN digital data processing system has been verified through the preliminary experiments such as data transmission, recording with VSI interface connection and data analysis between DSM and Mark5B system. In future work, we will perform the real astronomical observation by using the KVN 21m radio telescopes so as to verify its stability and performance.

• 한국지능시스템학회논문지
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• 제13권2호
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• pp.148-153
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• 2003

서비스 거부 공격은 침입을 위한 침입시도 형태로 나타나며 대표적인 공격으로 Syn Flooding 공격이 있다. Syn Flooding 공격은 신뢰성 및 연결 지향적 전송서비스인 TCP의 종단간에 3-way handshake의 취약점을 이용한 공격이다. 본 논문에서는 네트워크 기반의 지능적 침입 방지 모델을 제안한다. 제안하는 모델은 Syn Flooding 공격을 탐지하기 위하여 패킷 정보를 수집하고 분석한다. 이 모델은 퍼지인식도(Fuzzy Cognitive Maps)를 적용한 결정모듈의 분석 결과를 활용하여 서비스 거부 공격의 위험도를 측정하고 공격에 대응하도록 대응모듈을 학습시킨다. 제안하는 모델은 Syn Flooding 공격의 위험을 격감 또는 방지하는 네트워크 기반의 지능적 침입 방지 모델이다.

• 의학교육논단
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• 제22권3호
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• pp.189-197
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• 2020

The goal of this study is to present efficient measures to improve the quality of medical education through using a developed and applied continuous quality improvement (CQI) model suitable for medical education. To achieve this purpose, we developed a theoretical CQI model through a review of the literature according to the design-based research method. Through repetitive productive cyclical processes and professional reviews, we finally deduced an appropriate CQI model for medical education. The most important results of this study are as follows: First, the CQI model for medical education is defined as a quality management system with a cyclical course of planning, implementation, evaluation, and improvement of medical education. Second, the CQI model for medical education is composed of quality management activities of educational design, work, and evaluation. In addition, each activity has the implementation strategies of planning, doing, checking, and improving based on the PDCA model (Plan-Do-Check-Act model). Third, the CQI model for medical school education is composed of committees related to medical education doing improvement activities, as well as planning, implementing and evaluating it with CQI. As a result, we can improve teaching by using the CQI model for medical education. It is more meaningful because this gives us organized and practical measures of quality management and improvement in medical education as well as in the educational process.

• 한국균학회지
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• 제42권3호
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• pp.201-206
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• 2014

전라북도 고군산열도 선유도 일대에서 2014년 4월에 개화한 야생화들로부터 효모들을 분리한 후 이들의 26S rDNA의 D1/D2 부위의 염기서열을 결정한 다음 NCBI의 BLAST database에 등록되어 있는 효모들과의 상동성을 비교 분석하여 동정하였다. 야생화 51점에서 21종의 효모들을 61 균주 분리하였고, 이들 중 Cryptococcus aureus SY1-4 등의 Cryptococcus 속 균들이 가장 많았고, Metschnikowia reukaufii SY20-1등 Metschnikowia 속 균과 Rhodotorula ingeniosa SY1-1등 Rhodotorula 속 균들도 비교적 많이 분리되었다. 이들 61 균주들의 배양상등액과 무세포추출물을 제조한 후 생리기능성을 측정한 결과 M. reukaufii SY44-6의 배양상등액이 각각 49.6%의 XOD 저해활성과 38.4%의 미백성 Tyrosinase 저해활성을 보여 우수하였다.

• 한국초등과학교육학회지:초등과학교육
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• 제24권2호
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• pp.145-159
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• 2005

Students' alternative concepts of evolution are similar to misconcepts and disputes which scientists had in science history. The aims of this study are to analyze the elementary children's concept in evolution based on science history. Lee (2004)'s two tests were applied to 6th grade to investigate the children's evolution concepts and genetic concepts related to the historical development of the evolution concepts. The test results were analyzed in accordance with 4 stages of science history based on Lee (2004)'s method. These stages are divided to stage 1 (Before Lamarck), stage 2 (Lamarck), stage 3 (Darwin), stage 4 (After Darwin). The major results are as follows. Most of elementary school children are fixed to the stage 2. They usually do not show the consistency of evolution concepts in the three dimensional aspects such as mechanism, time, and subjects. Many children do not have concrete meaning of gene, inheritance, sexual reproduction, mutation and could not connect these concetps and process of evolution. Also, they believe the inheritance of acquired traits and spontaneous generation. Therefore it is confirmed that they still have similar misconcepts and disputes which scientists had in transition time between stage 2 and 3 and most of children already have strong Lamarckian thought acquired from daily life experience before learning about natural selection and evolution.

• 폴리머
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• 제35권4호
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• pp.284-288
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• 2011

초임계 유체에서 poly(L-Lactide) (PLLA)의 산업화 생산 공정 개발을 위한 예비 연구로 1-dodecano/stannous 2-ethyl-hexanoate(DoOH/Sn(Oct)$_2$)를 개시제로 하여 chlorodifluoromethane 초임계 용매 하에서 락티드의 개환 중합을 실시하였다. 중합은 3 L 반응기를 사용하였으며 중합시간, 온도, 압력 및 단량체와 초임계 용액 농도에 따른 중합거동을 관찰하였다. 중합시간이 5시간 경과할 경우 얻어진 중합체의 반응 수율 및 분자량은 각각 72%, 68000 g/mol이었다. 단량체의 농도가 증가할수록 중합체의 수율 및 분자량은 증가하였으며 최대 각각 97%, 144000 g/mol이 얻어졌다. 반응기의 압력이 130에서 240 bar로 증가할 경우 PLLA의 수율 및 분자량이 증가하였다. 얻어진 중합체의 열안정성을 향상시키기 위해 메탄올 처리 및 진공 처리를 실시하였다. 그 결과 두 가지 방법 모두 PLLA의 열안정성을 향상시켰다.

• The Journal of Korean Physical Therapy
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• 제33권3호
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• pp.131-135
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• 2021

Purpose: The purpose of this study was to investigate the mental health of physical therapy students in clinical practice during the COVID-19 pandemic. Methods: A cross-sectional survey was conducted during the pandemic and was completed by 100 physical therapy students in two universities in Gwangju and Jeollanam-do, South Korea. The Generalized Anxiety Disorder-7 (GAD-7) scale and the Patient Health Questionnaire-9 (PHQ-9) were used to evaluate their anxiety and depression status. A Chi-square test was conducted to evaluate the association of participant characteristics with the risk of having anxiety and depression. Logistic regression models were used to identify the general characteristic factors related to anxiety or depression. Results: Anxiety was found in 28 (28%) of the participants, and depression in 24 (24%). The risk of anxiety and depression in male physical therapy students was 0.189 and 0.211 times lower, respectively, than those female students (p<0.05). The risk of anxiety and depression in physical therapy students with a history of disease was 11.721 and 7.056 times higher, respectively, than those with a history of disease (p<0.05). The risk of anxiety in physical therapy students in clinical practice was 11.721 times higher than that in students who were not in clinical practice (p<0.05). Conclusion: The COVID-19 pandemic has led to a high risk of anxiety and depression among many physical therapy students. More attention and improvements are needed so that physical therapy students can study in a safe environment.

• 농촌계획
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• 제29권3호
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• pp.79-89
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• 2023

As the demand for environmental-friendly agricultural products continues to rise due to increased concerns regarding food safety and ecosystem conservation, it is becoming important to identify regions and spatial locations where environmental-friendly should be intensively established for production integration. This study aims to analyze the spatial distribution of environmental-friendly certified farms in Jeollanam-do, South Korea. Spatial statistical analysis based on Local Moran's I and Getis-Ord Gi^* were used to identify spatial cluster characteristics and landscape indices were utilized to analyze spatial patterns of environmental-friendly certified farms. The results indicated that Haenam-gun, Gangjin-gun, Muan-gun, and Jindo-gun were identified as hotspots, while Muan-gun, Goheung-gun, and Jindo-gun exhibited high connectivity. This suggests that environmental-friendly certified farms in Muan-gun and Jindo-gun were clustered and closely connected to one another. Based on the results of the spatial distribution of environmental-friendly certified farms, areas belonging to the hotspot and with high connectivity should be managed as clustered districts to secure the foundation and system of environmental-friendly certified farms. Areas that belong to cold spots and have low connectivity should be preceded by measures to promote conversion to environmental-friendly agriculture. In addition, it is necessary to make it possible to create a large-scale cluster district through a long-term spatial planning strategy to expand the environmental-friendly certified farms. The findings of this study can provide quantitative data on policies and discussions for developing a model for rural spatial planning.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.20-20
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• 2020

Eranthis stellata Maxim. is a perennial plant that grows around the valley. E. stellata is concerned about the decline in natural habitats due to climate change in KOREA, continues to be observed and protected as an endangered species (Least Concrned, LC). Nevertheless, studies on the characteristics of the seeds of E. stellata are insufficient. So, this study analyzed the morphological characteristics and dormancy types of seeds. Seeds of E. stellata was collected in April at Gyeongsangbuk-do Arboretum and kept at 5 ℃ until using. To investigate the morphology of seeds, an optical microscope and a scanning electron microscope (SEM) were used. GA3 treated or untreated seeds (4 replicates of 25 seeds each) were observed germination and embryo growth for 1 month at 5 ℃ and 25/15 ℃ (12h day/12h night). The seed surface of E. stellata, light brown, was observed as a common characteristic of Eranthis genus, reticulate. The short axis of seeds was 1.11~1.77mm (average 1.44mm), and the long axis was 1.27~1.91mm (average 1.63mm), which was investigated in a slightly round shape (subglose). While no germination was observed at all conditions, Embryo growth was observed at 5 ℃ both in the control group and with GA3treated groups. Thus, seeds of E. stellata are classified as morphological physiological dormancy (MDP), which requires embryonic development and dormant break at the same time. These results can be useful information for determining morphological physiological seed dormancy and germination, and will be an important basic data for seed propagation of E. stellata as a resource.