• Title/Summary/Keyword: $CP_1$

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Comparisons of Diaphragm Movement and Pulmonary Function Between Normal Children and Children With Cerebral Palsy (정상 아동과 뇌성마비 아동의 감소된 횡격막 움직임 및 호흡 기능의 비교)

  • Kang, Min-soo;Shim, Jae-hoon;Kang, Sun-young
    • Physical Therapy Korea
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    • v.25 no.1
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    • pp.12-21
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    • 2018
  • Background: Research efforts to improve the pulmonary function of children with cerebral palsy (CP) need to focus on their decreased diaphragmatic ability compared to normal children. Real-time ultrasonography is appropriate for demonstrating diaphragmatic mechanisms. Objects: This study aimed to compare diaphragm movement, pulmonary function, and pulmonary strength between normal children and children with CP by using ultrasonography M-mode. The correlation between general characteristics, diaphragm movement, pulmonary function, and pulmonary strength was also studied. Methods: The subjects of this study were 25 normal and 25 CP children between five and 14 years of age. Diaphragm movement was measured using real-time ultrasonography during quiet and deep breathing. Pulmonary function (such as forced expiratory volume in one second; FEV1 and peak expiratory flow; PEF) and pulmonary strength (such as maximum inspiratory pressure; MIP and maximum expiratory pressure; MEP) were measured. A paired t-test and Spearman's Rho test, with a significance level of .05, were used for statistical analysis. Results: The between-group comparison revealed that normal children had significantly greater diaphragm movement, FEV1, PEF, MIP, and MEP (p<.05) than CP children. The results showed that general characteristics were significantly related to FEV1, PEF, MIP, and MEP (p<.05). Conclusion: In clinical settings, clinicians need to concern decreased diaphragm movement, pulmonary function, and pulmonary strength in CP group compared to normal children.

Circulating Levels of Adipocytokines as Potential Biomarkers for Early Detection of Colorectal Carcinoma in Egyptian Patients

  • Zekri, Abdel-Rahman N;Bakr, Yasser Mabrouk;Ezzat, Maali Mohamed;Zakaria, Mohamed Serag Eldeen;Elbaz, Tamer Mahmoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.6923-6928
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    • 2015
  • Background: Early detection of various kinds of cancers nowadays is needed including colorectal cancer due to the highly significant effects in improving cancer treatment. The aim of this study was to evaluate the potential value of adiponectin, visfatin and resistin as early biomarkers for colorectal cancer patients. Materials and Methods: Serum levels of adiponectin, visfatin and resistin were measured by a sandwich-enzyme-linked (ELISA) assay technique in 114 serum samples comprising 34 patients with colorectal cancer (CRC), 27 with colonic polyps (CP), 24 with inflammatory bowel disease (IBD) and 29 healthy controls. The diagnostic accuracy of each serum marker was evaluated using receiver-operating characteristic (ROC) curve analysis. Results: The mean concentration of adiponectin was significantly higher in CRC and CP groups than IBD and control groups (P-value <0.05). Also the mean concentration of serum resistin was significantly elevated in the IBD and control groups compared to CRC and CP groups (P-value = 0.014). However, no significant difference was noted in patients of the CRC and CP groups. On the other hand, the mean concentration of visfatin was significantly elevated in CRC and control groups compared to CP and IBD groups (P-value = 0.03). ROC analysis curves for the studied markers revealed that between CRC and IBD groups serum level of adiponectin had a sensitivity of 76.7% and a specificity of 76% at a cut off value of 3940, +LR being 3.2 and -LR 0.31 with AUC 0.852, while serum level of adiponectin between CP and IBD had a sensitivity of 77.8% and a specificity of 75% at a cut off value of 3300, with +LR=3.11 and -LR = 0.3 with AUC 0.852. On the other hand the serum level of visfatin between CRC and CP groups had a sensitivity of 65.5% and a specificity of 66.7 at a cut off value of 2.4, +LR being 1.67 and -LR 0.52 with AUC 0.698. Also the serum level of resistin had a sensitivity of 62.5% and a specificity of 70.3% at a cut off value of 24500, with +LR=2.1 and -LR = 0.53 with AUC 0.685 between control and other groups. On the other hand by comparing control vs CP groups resistin had a sensitivity of 81.8% and a specificity of 70.8% at a cut off value of 17700, with +LR=2.8 and -LR = 0.26 with AUC 0.763 while visfatin had a sensitivity of 68.2% and a specificity of 70.8% at a cut off value of 2.7, with +LR=2.34 and -LR = 0.0.45 with AUC 0.812. Conclusions: These findings support potential roles of adiponectin, visfatin and resistin in early detection of CRC and discrimination of different groups of CRC, CP or IBD patients from normal healthy individuals.

Effect of Fluoridated 10% Carbamide Peroxide on Enamel Surface Change and Whitening (불소를 첨가한 10% Carbamide Peroxide의 법랑질표면 변화와 미백효과)

  • Lee, Hye-Jin;Kim, Hyun-Dae;Kim, Min-Young;Kwon, Tae-Yub;Kim, Kyo-Han
    • Journal of dental hygiene science
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    • v.10 no.2
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    • pp.95-100
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    • 2010
  • The purposes of this study were to examine the effect of different fluoridated bleaching solution on the changes in physical and chemical characteristics of tooth. Forty-eight bovine incisors were divided into four groups to receive bleaching treatments, over a 14days period, as follows: no treatment; 10% carbamide peroxide (CP) bleaching; 10% CP containing 0.05% fluoride; and 10% CP containing 0.1% fluoride. All the specimens were highly polished and discolored with commercial COCK.Color and enamel changes were determined with colorimeter, microhardness tester, scanning electron microscope, atomic force microscopy. All the collected data were analyzed with one-way ANOVA. After the bleaching, bleached groups showed the color change(E*). Microhardness of 10% CP group decreased after tooth bleaching. But microhardness of containing fluoride bleached groups increased after tooth bleaching. Enamel surface of 10% CP bleached group showed any apparent morphology and roughness changes compared to the enamel which was stored in distilled water only. These results demonstrated that Fluoridated 10% Carbamide Peroxide have appreciable bleaching effect on bovine teeth and were not adversely affects enamel. Supporting influence of fluoride-containing bleaching solution on remineralization could be observed and further research must be carried out in various active environments to confirm these results clinically.

The Biocompatibility Of Cultured Bone Marrow Cells And Gingival Fibroblasts On The Titanium Surfaces (티타늄 배양에 대한 배양골수와 치은 섬유아세포의 생체적합성)

  • Oh, Choong-Young;Park, Joon-Bong;Kwon, Young-Hyuk;Lee, Man-Sup
    • Journal of Periodontal and Implant Science
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    • v.26 no.1
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    • pp.143-160
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    • 1996
  • The purpose of this study was to evaluate the response in aspect of attachment and growth rate of osteoblasts and growth rate of osteoblasts and human gingival fibroblasts to the commercially pure titanium(CP titanium)and titanium alloy(Ti-6AI-4V) that are used widely as implant materials, and to obtain the basic information to ideal implant materials. In the studly, commercially pure titanium in first test group, titanium alloy(Ti-6AI-4V) in second test group, cobalt-chrome-molybdenum alloy(Co-Cr-Mo alloy) in positive control group, and tissue culture polystyrene plate in negative control group were used. The results of this study were as follows. 1. Bone marrow cells cultured on CP titanium and Ti-6Al-4V showed significantly greater attachment and growth rate(p(0.05) compared to Co-Cr-Mo alloy in each time. 2. There were no significant differences(p>0.05) in attachment and growth rate of bone marrow cells cultured on CP titanium and Ti-6AI-4V or tissue culture plate. 3. Most bone marrow cells cultured on CP titanium, Ti-6Al-4V and tissue culture plate were attached well to each substratum in first 2days, and then, grew at higher growth rate. On the other hand, some cells cultured on Co-Cr-Mo alloy failed to attach in first 2 days, and then, attached cells grew at lower growth rate than other groups. 4. Attachment and growth rates of gingival fibroblasts cultured on CP titanium and Ti-6Al-4V showed no significant differences(p>0.05) compared to Co-Cr-Mo alloy in 2 days, but significantly greater increase(p<0.05) in 5 and 9 days. 5. There were no significantly differences(p>0.05) between growth rates on gingival fibroblasts cultured on CP titanium, Ti-6Al-4V and tissue culture plate in 2 and 5days, but a significant lower growth rate(p<0.05) on CP titanium and Ti-6Al-4V versus tissue culture plate. 6. Some gingival fibroblasts cultured on all specimen groups failed to attach, but attached cells grew well, especially on CP titanium, Ti-GAl-4V and tissue culture plate. 7. There were no significant differences(P>0.05) between growth rates of both bone marrow cells and gingival fibroblasts cultured on CP titanium and Ti-6AI-4V. As a result of this study, both commercially pure titanium and Ti-6AI-4V showed excellent biocompatibility and there was no significant difference in the cellular response to the both metals. Bone marrow cells cultured on each substratum showed significantly greater growth rate and responded sensitively to cytotoxic effects of metal surfaces compared to gingival fibroblasts. Considering cell response to the substrate, it was likely that the composition itself of titanium metals have no significant effect on the biocompatibility. Further study need to be done to evaluate the influence of surface characteristics on cellular responses.

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The Effects of Chungpyesagan-tang on the Recovery of Liver Function in Rat Injured by $CCl_4$ (청폐사간탕(淸肺瀉肝湯)이 $CCl_4$로 유발(誘發)된 휜쥐의 간손상(肝損傷)에 마치는 영향(影響))

  • Shin, Mee-Ran;Heo, Woon-Yeong;Kim, DaI-Rae;Jeon, Jong-Weon;Kim, Jeong-Yeol
    • Journal of Sasang Constitutional Medicine
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    • v.17 no.1
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    • pp.130-141
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    • 2005
  • 1. Objectives The present study was carried out to investigate the effects of Chungpyesagan-tang on the $CCI_4-induced$ Liver Damage in Rats. 2. Methods Sprague-Dawley rats were devided into 5 experimental groups : Normal, $NS+CCI_4(Solid$ extract of $CCI_4$ injection group after Normal Saline feed), $CP+CCI_4(Solid$ extract of $CCI_4$ injection group after Chungpyesagantang feed), $CCI_4+NS(Nomal$ Saline feed group after $CCI_4$ injection), $CCI_4+CP(Solid$ extract of Chungpyesagantang feed group after $CCI_4$ injection). Biochemical assays for serum enzyme activities such as AST, ALT, ALP, BUN, Creatinine, Uric Acid, Total Protein, Albumin, Total Cholesterol, Triglyceride, Glucose, and mRNA Revelation of Cytochrome p450 and activities such as LPO(Lipid Peroxidation), GSH(Glutathione), GST(Glutathione-S- Transferase), Glutathione Reductase, Glutathione Peroxidase, SOD(Superoxide Dismutase), Catalase, Hydroxyproline, and ${\beta}-Glucuronidase$ were performed. 3. Results 1) $CP+CCI_4$ showed significantly lower relation of Cytochrome p450 than $NS+CCI_4$. 2) As to LPO Hydroxyproline, $CCI_4+CP$ showed significantly lower activity than $CCI_4+NS$. 3) As to GSH GST Glutathione Peroxidase Catalase, $CP+CCI_4$ showed higher activity than $NS+CCI_4$, $CCI_4+CP$ showed significantly higher activity than $CCI_4+NS$. 4) As to Glutathione Reductase SOD, $CCI_4+CP$ showed significantly higher activity than $CCI_4+NS$. 5) As to ${\beta}-Glucuronidase$, $CP+CCI_4$ showed signficantly lower activity than $NS+CCI_4$. 4. Conclusions Chungpyesagantang has the recovering effects on the $CCI_4-induced$ Liver Damage.

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The Classification Algorithm of Users' Emotion Using Brain-Wave (뇌파를 활용한 사용자의 감정 분류 알고리즘)

  • Lee, Hyun-Ju;Shin, Dong-Il;Shin, Dong-Kyoo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.2
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    • pp.122-129
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    • 2014
  • In this study, emotion-classification gathered from users was performed, classification-experiments were then conducted using SVM(Support Vector Machine) and K-means algorithm. Total 15 numbers of channels; CP6, Cz, FC2, T7. PO4, AF3, CP1, CP2, C3, F3, FC6, C4, Oz, T8 and F8 among 32 members of the channels measured were adapted in Brain signals which indicated obvious the classification of emotions in previous researches. To extract emotion, watching DVD and IAPS(International Affective Picture System) which is a way to stimulate with photos were applied and SAM(Self-Assessment Manikin) was used in emotion-classification to users' emotional conditions. The collected users' Brain-wave signals gathered had been pre-processing using FIR filter and artifacts(eye-blink) were then deleted by ICA(independence component Analysis) using. The data pre-processing were conveyed into frequency analysis for feature extraction through FFT. At last, the experiment was conducted suing classification algorithm; Although, K-means extracted 70% of results, SVM showed better accuracy which extracted 71.85% of results. Then, the results of previous researches adapted SVM were comparatively analyzed.

The Style of Categories of Poetry and Seclusive Thinking of Korean Traditional Architecture (시품의 풍격과 한국 전통건축의 은둔적 사유)

  • Rhee, Joo-Hee;Lee, Jeong-Wook
    • Korean Institute of Interior Design Journal
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    • v.25 no.1
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    • pp.101-114
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    • 2016
  • In the center of our ancestor's culture, there were poetry, calligraphy, and painting. Above all, poetry was the heart of the culture involved in everyday life. The beauty of poetry was not limited to appreciation of the poetry but it influenced calligraphy, painting, seals, music, architecture and even how the ancestors viewed their lives. Categories of poetry(詩品, CP hereafter) is the poetry written to deliberate the style of poems and its influence went beyond the fields of calligraphy and painting. Even now, our architecture reflects the sentimental influences and values of CP. In order to understand the attitude, mind, and the world view of the architects in the past, comprehensive and deep understanding of their philosophy as well as their cultural and social norms is needed. In this paper, CP is used as the means to investigate and develop such understanding of our ancestors' philosophy and culture. This paper also intends to investigate how the seclusive thinking of Neo-Confucianism is reflected in CP and the overall literature. In addition, this paper aims to examine the trace of CP in traditional architecture as well as the relationships and the flow among various styles of CP. This study therefore serves as an important base in understanding the ancestor's philosophy that pursued balance between life and art, reason and emotion, study and practice, and their architectural expression. It is also expected that this study would work as the groundwork to regain our traditional culture identity.

Determination of Protein Requirements for Maintenance of Elk Doe

  • Kim, Kwan-Woo;Lee, Jinwook;Kim, Dong-Gyo;Lee, Eun-Do;Lee, Sung-Soo;Kim, Do Hyung;Lee, Sang-Hoon
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.40 no.3
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    • pp.177-181
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    • 2020
  • Data on the crude protein requirements of elk doe are nonexistent and the data are essential for their management in Korea. Therefore, this study was conducted to evaluate the crude protein requirement for maintenance of elk doe. Three female elk deer were used in 3 × 3 Latin square design with three diets containing three levels of crude protein (CP) that contained low crude protein (approximately 12%), medium crude protein (15%), and high crude protein (18%). Each three elk doe trials included a 14-day preliminary period and a 5-day collection period. Crude protein intake was 4.83, 6.26, and 9.00 g/d for 12%, 15%, and 18% of CP level, respectively. Crude protein balances were 1.04, 1.41, and 4.14 for 12%, 15%, and 18% of CP level, respectively. The maintenance requirement for CP from the regression equation between CP intake and CP balance were 3.70 g/BW0.75.

Treatment of Benzene Vapor Gas with Compost and Calcium Silicate Porous Biofilters (퇴비 및 규산칼슘계 다공성 바이오필터의 벤젠휘발가스 처리)

  • Park, Joon-Seok;Namkoong, Wan;Kim, Sun-A;Park, Young-Goo;Lee, Noh-Sup
    • Journal of the Korean Applied Science and Technology
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    • v.22 no.1
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    • pp.21-27
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    • 2005
  • This study was conducted to evaluate the biofiltration treatment characteristic for benzene vapor gas. Compost and calcium silicate porous material were used as biofilter fillers. Gas velocity and empty bed retention time were 15 m/hr and 4 min, respectively. Benzene gas removal efficiency of P-Bio (calcium silicate porous material with inoculation) was the highest and maintained in over 98%. After shock input of benzene gas, the removal efficiency of P-Bio biofilter was recovered within 2 days, while 5 days were taken in CP-Bio (compost + calcium silicate porous material mixture with inoculation) and CP (compost + calcium silicate porous material mixture without inoculation) biofilters. The removal efficiency of P-Bio biofilter was near 100% in the loading rate of <$85g/m^3$(filling material)/hr, It was shown that the maximum elimination capacities of P-Bio, CP-Bio, and CP biofilters were 95, 69, and $66\;g/m^3$(filling material)/hr, respectively. Microbial number of P-Bio, which the number was the lowest at start-up, was 3 orders increased on operational day 48. $CO_2$ was generated greatly in order of P-Bio, CP-Bio, and CP biofilters.

A New Carrier frequency Offset Estimation Using CP-ICA Scheme in OFDM Systems (OFDM 시스템에서 CP-ICA 기법을 이용한 새로운 주파수 옵셋 추정)

  • Kim, Jong-Deuk;Byun, Youn-Shik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.12C
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    • pp.1257-1264
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    • 2006
  • The carrier frequency offset causes loss of orthogonality between sub-carriers, thus leads to inter-carrier interference (ICI) in the OFDM symbol. This ICI causes severe degradation of the BER performance of the OFDM receiver. In this paper, we propose a new ICI cancellation algorithm which estimates frequency offset at the time-domain by using CP-ICA method to the received sub-carriers phase rotation. This algorithm is based on a statistical blind estimation method, which mainly utilizes the EVD, rotating phase and the $4^{th}-cumulants$. Since our scheme does not need any training and pilot symbol in estimation, we can expect enhanced bandwidth efficiency in OFDM systems. Simulation results show that the proposed frequency offset estimator is more accurate than the other estimators in $0.0<\varepsilon<1.0$.