• Title/Summary/Keyword: $C^*$-매개변수

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Pharmacokinetics of oxytetracycline in olive flounder (Paralichthys olivaceus) by intramuscular injection (Oxytetracycline을 근육 주사한 넙치 (Paralichthys olivaceus)의 약물동태학적 특성)

  • Jung, Sung-Hee;Choi, Dong-Lim;Kim, Jin-Woo;Jo, Mi-Ra;Seo, Jung-Soo;Ji, Bo-Young
    • Journal of fish pathology
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    • v.22 no.1
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    • pp.91-95
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    • 2009
  • The pharmacokinetic properties of oxytetracycline (OTC) were studied after intramuscular injection to cultured olive flounder, Paralichthys olivaceus. Plasma concentrations of OTC were determined after dosage of 12.5, 25 and 50 ㎎/㎏ body weight in olive flounder (average 600 g, $23{\pm}1{^{\circ}C}$). Plasma samples were taken at 3, 5, 10, 15, 24, 32, 48, 72, 120, 168, 240 and 360 h post-dose. With 25 and 50 ㎎/㎏, the peak plasma concentrations of OTC, which attained at 5 h post-dose, were 0.99 and 1.49 $\mu{g}/m\ell$, respectively. However, the peak plasma concentration of 12.5 ㎎/㎏ was 0.35 $\mu{g}/m\ell$ after 10 h post-dose. Plasma concentrations of OTC were not measurable at 360 h post-dose in all doses. The kinetic profile of absorption, distribution and elimination of OTC in plasma were analyzed fitting to a 1-compartment model by Win-Nonlin program. The following parameters were calculated for 12.5, 25 and 50 ㎎/㎏ body weight, respectively: AUC (the area under the concentration-time curve)?D���D24.98, 44.67 and 50.45 $\mu{g}$ $h/m\ell$ $T_{1/2}$ (half-life) ?D���D0.42, 0.59 and 0.41 h; $T_{max}$ (time for maximum concentration)?D���D8.46, 6.34 and 2.66 h; $C_{max}$ (maximum concentration)?D���D0.30, 0.63 and 1.13 $\mu{g}/m\ell$.

Ecological Characteristics of Squalidus chankaensis tsuchigae (Cyprinidae) in Geum River, Korea (금강에 서식하는 참몰개 Squalidus chankaensis tsuchigae (Cyprinidae)의 생태 특성)

  • Byeon, Hwa-Keun;Yoon, Min-Ho
    • Korean Journal of Environment and Ecology
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    • v.30 no.5
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    • pp.888-895
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    • 2016
  • The population ecology (Ecological characteristics) of Squalidus chankaensis tsuchigae were investigated at Geum River from March to November, 2013. This species inhabited midstream of the river where was mostly covered with cobble and sand. The depth of the habitat was 30~60 cm and velocity of stream was 2.27~4.88 cm/sec. The sex ratio of female to male was 1 : 0.86. They were sexually mature when they were over two years of age. The spawning period was from June to July with water temperatures from $25^{\circ}C$ to $25^{\circ}C$. Sexually matured individuals appeared over the two year of age. Frequency analysis of total length indicated that the group with 55~70 mm in total length was one year old, the 71~90 mm was two years old, and the group over 91 mm was three years old. The average number of eggs in the ovaries was estimated as 2,219 per matured female. The number of matured eggs size in ovaries was 0.64~0.98 (mean: 0.85) mm. Calulation length-weight relation of S. chankaensis tsuchigae show the value of contant a as 0.0002 and b as 2.81, and condition factor (K) was 1.06 on average. The stomach contents were Cyanophyta, Chlorophyta, Bacillariophyta, Crustaceae, Copepoda, Nematota, Actithocephala, and Ephemeroptera, Hemiptera, Diptera, and Trichoptera that belong to Aquatic insect, and dormant bud of Pectinatella that belongs to Phylactolaemata. The diet of S. chankaensis tsuchigae was omnivorous, mainly vegetable feed on attached algae (filament form), and mainly animality feeded on benthic invertebrates such as Chironomidae larvae.

A study on evaluation of flexural toughness of synthetic fiber reinforced shotcrete (구조용 합성섬유 보강 숏크리트 휨인성 평가에 관한 연구)

  • Moon, Kyoung-Sun;Kim, Seog-Jin;Kim, Yeon-Deok;Min, Byeong-Heon;Kim, Sang-Hwan
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.21 no.3
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    • pp.433-452
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    • 2019
  • This study deals with shotcrete reinforcing performance according to the amount of synthetic fiber (PP fiber) and proper evaluation method. The shotcrete compressive strength, flexural strength and flexural toughness were tested by setting the mixing amounts of steel fiber ($37.0kg/m^3$) and synthetic fiber (PP fiber) as parameters ($5.0kg/m^3$, $7.0kg/m^3$ and $9.0kg/m^3$). Particularly, circular panel flexural toughness test (Road and Traffic Authority, RTA) was performed to evaluate the shotcrete energy absorption capacity. As a result, the compressive strength and the bending strength of the steel fiber reinforced shotcrete were large, but the flexural toughness of the synthetic fibe (PP fiber) reinforced shotcrete was large. Therefore, synthetic fiber (PP fiber) reinforced shotcrete is considered to have a reinforcing effect comparable to that of steel fiber reinforced shotcrete. Analysis of the relationship between the flexural toughness and the energy absorption capacity of synthetic fiber (PP fiber) reinforced shotcrete revealed that the energy absorbing ability is exhibited at a flexural toughness lower than the allowable standard (3.0 MPa). (Class A: 2.55 MPa = 202J, Class B: 2.72 MPa = 282J, Class C: 3.07 MPa = 403J). As a result of this study, it can be concluded that the actual shotcrete support performance can be evaluated by evaluating the support performance of the shotcrete measured at less than the allowable standard (3.0 MPa) at the actual tunnel site.

Evaluation of Parameter Estimation Method for Design Rainfall Estimation (설계강우량 산정을 위한 매개변수 추정방법 평가)

  • Kim, Kwihoon;Jun, Sang-Min;Jang, Jeongyeol;Song, Inhong;Kang, Moon-Seong;Choi, Jin-Yong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.63 no.4
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    • pp.87-96
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    • 2021
  • Determining design rainfall is the first step to plan an agricultural drainage facility. The objective of this study is to evaluate whether the current method for parameter estimation is reasonable for computing the design rainfall. The current Gumbel-Kendall (G-K) method was compared with two other methods which are Gumbel-Chow (G-C) method and Probability weighted moment (PWM). Hourly rainfall data were acquired from the 60 ASOS (Automated Synoptic Observing System) stations across the nation. For the goodness-of-fit test, this study used chi-squared (𝛘2) and Kolmogorov-Smirnov (K-S) test. When using G-K method, 𝛘2 statistics of 18 stations exceeded the critical value (𝑥2a=0.05,df=4=9.4877) and 10, 3 stations for G-C method, PWM method respectively. For K-S test, none of the stations exceeded the critical value (Da=0.05n=0.19838). However, G-K method showed the worst performances in both tests compared to other methods. Subsequently, this study computed design rainfall of 48-hour duration in 60 ASOS stations. G-K method showed 5.6 and 6.4% higher average design rainfall and 15.2 and 24.6% higher variance compared to G-C and PWM methods. In short, G-K showed the worst performance in goodness-of-fit tests and showed higher design rainfall with the least robustness. Likewise, considering the basic assumptions of the design rainfall estimation, G-K is not an appropriate method for the practical use. This study can be referenced and helpful when revising the agricultural drainage standards.

Environmental Studies in the Lower Part of the Han River VIII. Physicochemical Factors Contributing to Variation of Phytoplankton Communities (한강 하류의 환경학적 연구 VIII. 식물플랑크톤 군집의 변화에 미치는 물리 화학적 요인)

  • Kwon, Oh-Youn;Jung, Seung-Won;Lee, Jin-Hwan
    • Korean Journal of Ecology and Environment
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    • v.39 no.3 s.117
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    • pp.340-351
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    • 2006
  • To reveal physicochemical factors contributing to variation of phytoplankton communities, the study was carried out biweekly at 6 stations from Feb. 2004 to Feb. 2005 in the lower part of the Han River, Korea. As results, water temperature was changed from $0.3^{\circ}C$ to $26.6^{\circ}C$, pH: 6.6${\sim}$9.1, DO: 1.89${\sim}$22.23 mg $L^{-1}$, BOD: 0.38${\sim}$9.20 mg $L^{-1}$, COD: 1.4${\sim}$15.2 mg $L^{-1}$, Conductivity: $62.5{\sim}500.0\;{\mu}s\;cm^{-1}$, SS: 3.00${\sim}$159.3 mg $L^{-1}$, and Chl a $1.7{\sim}71.3\;{\mu}g\;L^{-1}$. Phytoplankton standing crops ranged from min. $3.6{\times}10^2\;cells\;mL^{-1}$ (July 2004, St. 3) to max. $2.3{\times}10^4\;cells\;mL^{-1}$ (Feb. 2005, St. 6), and mean of those varied from $5.9{\times}10^3\;cells\;mL^{-1}$in spring, $2.1{\times}10^3\;cells\;mL^{-1}$ in summer, $4.1{\times}10^3\;cells\;mL^{-1}$ in autumn and $8.5{\times}10^3\;cells\;mL^{-1}$ in winter, respectively. In order to investigate factors influencing the total phytoplankton standing crops a multiple regression analysis was adopted for the correlation between standing crops and environmental factors. The coefficient of determination ($R^2$) value of the regression was 0.465, it showed that environmental factors which predominantly influenced phytoplankton standing crops were water temperature, COD, $NO_2-N$, $PO_4-N$, Discharge and pH. six stations could be divided into 3 groups based on similarity index in terms of environmental factors. In ANOVA analysis for physicochemical and biological factors, water temperature, chlorophyll a, silicate, phytoplankton standing crops were the same group differed little from stations. However, Station 1and 2 were grouped followed in dissolved oxygen, conductivity, COD, nitrite, nitrate, ammonia and phosphate, and Station 3, 4 and 5 were followed in dissolved oxygen, conductivity, pH and phosphate.

Temperature-driven Models of Lipaphis erysimi (Hemiptera: Aphididae) Based on its Development and Fecundity on Cabbage in the Laboratory in Jeju, Korea (양배추에서 무테두리진딧물의 온도의존 발육 및 산자 단위모형)

  • Oh, Sung Oh;Kwon, Soon Hwa;Kim, Tae Ok;Park, Jeong Hoon;Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.55 no.2
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    • pp.119-128
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    • 2016
  • This study was conducted to develop temperature-driven models for a population model of turnip aphid, Lipaphis erysimi: nymphal development rate models and apterious adult's oviposition (larviparous) model. Nymphal development and the longevity and fecundity of adults were examined on cabbage at six constant temperatures (10, 15, 20, 25, 30, $35{\pm}1^{\circ}C$, 16L:8D). L. erysimi nymphs did not survive at $10^{\circ}C$. Development time of nymphs increased with increasing temperature up to $30^{\circ}C$ and thereafter slightly decreased, ranging from 18.5 d at $15^{\circ}C$ to 5.9 d at $30^{\circ}C$. The lower threshold temperature and thermal constant were estimated as $7.9^{\circ}C$ and 126.3 degree days, respectively. The nonlinear model of Lactin 2 fitted well for the relationship between the development rate and temperature of small (1+2 instar), large (3+4 instar) and total nymph (all instars). The Weibull function provided a good fit for the distribution of development times of each stage. Temperature affected the longevity and fecundity of L. erysimi. Adult longevity decreased as the temperature increased and ranged from 24.4 d at $20^{\circ}C$ to 16.4 d at $30.0^{\circ}C$ with abnormal longevity 18.2 d at $15^{\circ}C$, which was used to estimate adult aging rate model for the calculation of adult physiological age. L. erysimi showed a maximum fecundity of 91.6 eggs per female at $20^{\circ}C$. In this study, we provided three temperature-dependent components for an oviposition model of L. erysimi: total fecundity, age-specific cumulative oviposition rate, and age-specific survival rate.

Temperature-dependent Development and Fecundity of Rhopalosiphum padi (L.) (Hemiptera: Aphididae) on Corns (옥수수에서 기장테두리진딧물의 온도 의존적 발육과 산자 특성)

  • Park, Jeong Hoon;Kwon, Soon Hwa;Kim, Tae Ok;Oh, Sung Oh;Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.55 no.2
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    • pp.149-160
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    • 2016
  • Temperature-dependent development and fecundity of apterious Rhopalosiphum padi (L.) (Hemiptera: Aphididae) were examined at six constant temperatures (10, 15, 20, 25, 30 and $35{\pm}1.0^{\circ}C$, RH 50-70%, 16L:8D). Development time of nymphs decreased with increasing temperature and ranged from 42.9 days at $10^{\circ}C$ to 4.7 days at $30^{\circ}C$. The nymphs did not develop until adult at $35^{\circ}C$ because the nymphs died during the 2nd instar. The lower threshold temperature and thermal constant of nymph were estimated as $8.3^{\circ}C$ and 101.6 degree days, respectively. The relationships between development rates of nymph and temperatures were well described by the nonlinear model of Lactin 2. The distribution of development times of each stage was successfully fitted to the Weibull function. The longevity of apterious adults decreased with increasing temperature ranging from 24.0 days at $15^{\circ}C$ to 4.3 days at $30^{\circ}C$, with abnormally short longevity of 11.1 days at $10^{\circ}C$. R. padi showed the highest fecundity at $20^{\circ}C$ (38.2) and the lowest fecundity at $10^{\circ}C$ (3.9). In this study, we provided component sub-models for the oviposition model of R. padi: total fecundity, age-specific cumulative oviposition rate, and age-specific survival rate as well as adult aging rate based on the adult physiological age.

Temperature-dependent Oviposition Model and Life Table Parameters of Paromius exiguus (Distant) (Hemiptera: Lygaeidae) Growing on Rice (벼에서 흑다리긴노린재 [Paromius exiguus (Distant)] (Hemiptera: Lygaeidae) 산란모델 및 생명표)

  • Park, Chang-Gyu;Park, Hong-Hyeon;Seo, Bo Yoon
    • Korean journal of applied entomology
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    • v.56 no.4
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    • pp.387-394
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    • 2017
  • Temperature-dependent oviposition model and life table parameters of Paromius exiguus (Distant), the causal agent of 'pecky' rice grain were examined at eight constant temperatures (17.5, 20, 22.5, 25, 27.5, 30, 32.5, and $35{\pm}^{\circ}C$) and a photoperiod of 14:10 (L:D) h. Unit functions of the oviposition model were developed and life table parameters were estimated. The longevity of P. exiguus adults decreased with increasing temperature (123.8 days at $17.5^{\circ}C$ and 23.6 days at $32.5^{\circ}C$). Total fecundity was highest at $30^{\circ}C$ (585.2 eggs/female) and lowest at $17.5^{\circ}C$ (21.5 eggs/female). In order to develop a temperature-dependent oviposition model, adult aging-rate, temperature-dependent fecundity, age-specific survival rate, and age-specific cumulative oviposition rate equations were estimated. All unit equations ($r^2=0.92{\sim}0.98$) except for the temperature-dependent fecundity equation ($r^2=0.83{\sim}0.85$), described oviposition characteristics of P. exiguus adequately. Life table parameters of P. exiguus were estimated at various constant temperatures. Net reproduction rate ($R_0$) was highest at $30^{\circ}C$ (118.21). Mean generation time (T) was shortest at $32.5^{\circ}C$ (32.99 days) and doubling time (Dt) was shortest at $30^{\circ}C$ (5.69 days). The highest values of intrinsic rate of increase ($r_m$) and finite rate of increase (${\lambda}$) were 0.122 and 1.129 at $30^{\circ}C$, respectively.

The Temperature-Dependent Development of the Parasitoid Fly, Exorista Japonica (Townsend) (Diptera: Tachinidae) (항온조건에서 긴등기생파리 [Exorista japonica (Townsend)] (Diptera: Tachinidae) 온도별 발육)

  • Park, Chang-Gyu;Seo, Bo Yoon;Choi, Byeong-Ryoel
    • Korean journal of applied entomology
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    • v.55 no.4
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    • pp.445-452
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    • 2016
  • Exorista japonica is one of the major natural enemies of noctuid larvae, Mythimna separata and Spodoptera litura. The examined parasitoid was obtained from host species M. separata, collected at Gimje city and identified by DNA sequences (partial cytochrome oxidase I, 16S, 18S, and 28S). For purposed of this study, laboratory reared S. litura served as the host species for the development of the E. japonica. The developmental period of E. japonica immature stages were investigated at seven constant temperatures (16, 19, 22, 25, 28, 31, $34{\pm}1^{\circ}C$, RH 20~30%). Temperature-dependent developmental rates and development completion models were developed. E. japonica was successfully developed from egg to adult in $16{\sim}31^{\circ}C$ temperature regimes. Developmental duration was the shortest at $34^{\circ}C$ (8.3 days) and the longest at $16^{\circ}C$ (23.4 days) from egg to pupa development. Pupal development duration was the shortest at $28^{\circ}C$ (7.3 days). Total immature-stage development duration decreased with increasing temperature, and was the shortest at $31^{\circ}C$ (16.3 days) and the longest at $16^{\circ}C$ (45.4 days). The lower developmental threshold was $7.8^{\circ}C$ and thermal constant required to complete total immature-stage development was 370.4 degree days. Among four non-linear temperature-dependent developmental rate models, Briere 1 model had the highest adjusted R-squared (0.96). The distribution model of development completion for total immature stage development of E. japonica was well described by all model ($r^2_{adj}=0.90$) based on the standardized development duration. These results of study would be necessary not only to develop population dynamics model but also to understand fundamental biology of E. japonica.

An Effects of Authentic Leadership and Transformational Leadership on Change Supportive Behavior in Small and Medium-size Business: Focused on Mediating Effect of Positive Psychological Capital (중소기업에서 상사의 변혁적 리더십과 진성 리더십이 변화지지행동에 미치는 영향: 긍정심리자본의 매개효과에 관한 연구)

  • Kim, Kyu Han;Huh, Chul Moo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.14 no.2
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    • pp.135-149
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    • 2019
  • Today, a growing number of companies are in trouble because leaders are lack of authentic leadership. Small and midium sized companies have the same issue. To correct the issue, there must be a real change in the relationship between managers and employees of the company as well as outside the company. In 21st century, authentic leadership is required. However, the research about determinants of change supportive behavior is not sufficient. Therefore, the purpose of this study is how manager's transformational leadership and authentic leadership affects change supportive behavior of employees in small and midium sized companies. The study also has to prove the role of positive psychological capital as a parameter. Data were collected from 424 employees working for small and midium sized companies in metropolitan area around Seoul and Gyeonggi. The data were analyzed using statistical package SPSS ver.21.0 and AMOS ver.18.0. Based on the research, First, the transformational leadership does not affect the change supportive behavior. However, authentic leadership affects the change supportive behavior. Also, positive psychological capital playes a role as parameter when transformational and authentic leadership, that are independent variable, affect change supportive behavior. On the other hand, the research shows that authentic leadership has more influence than transformational leadership on positive psychological capital. Transformational leadership without genuine attitude cannot affect change support behavior of employees in small and medium sized companies. Therefore, to affect change supportive behavior of employee, authentic leadership with genuine mind is required. After discussing the conclusions and implications of this study. the direction of the study for the follow - up study was suggested.