• Title/Summary/Keyword: $B_{10}$ lifetime

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BENZENE AND LEUKEMIA An Epidemiologic Risk Assessment

  • Rinsky Robert A.;Smith Alexander B.;Hornung Richard;Filloon Thomas G.;Young Ronald J.;Okun Andrea H.;Landrigan Philip J.
    • 대한예방의학회:학술대회논문집
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    • 1994.02a
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    • pp.651-657
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    • 1994
  • To assess quantitatively the association between benzene exposure and leukemia, we examined the mortality rate of a cohort with occupational exposure to benzene. Cumulative exposure for each cohort member was estimated from historical air-sampling data and, when no sampling data existed, from interpolation on the basis of existing data. The overall standardized mortality ratio (a measure of relative risk multiplied by 100) for leukemia was 337 (95 percent confidence interval, 154 to 641), and that for multiple myeloma was 409 (95 percent confidence interval, 110 to 1047). With stratification according to levels of cumulative exposure, the standardized mortality ratios for leukemia increased from 109 to 322, 1186, and 6637 with increases in cumulative benzene exposure from less than 40 parts per million-years (ppm-years), to 40 to 199, 200 to 399, and 400 or more. respectively. A cumulative benzene exposure of 400 ppm years is equivalent to a mean annual exposure of 10 ppm over a 40-year working lifetime; 10 ppm is the currently enforceable standard in the United States for occupational exposure to benzene. To examine the shape of the exposure-response relation, we performed a conditional logistic-regression analysis, in which 10 controls were matched to each cohort member with leukemia. From this model, it can be calculated that protection from benzene induced leukemia would increase exponentially with any reduction in the permissible exposure limit.

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Comparison of Storage Lifetimes by Variance Assumption using Accelerated Degradation Test Data (파괴적 가속열화시험 데이터의 분산가정에 따른 수명비교)

  • Kim, Jonggyu;Back, Seungjun;Son, Youngkap;Park, Sanghyun;Lee, Moonho;Kang, Insik
    • Journal of the Korea Institute of Military Science and Technology
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    • v.21 no.2
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    • pp.173-179
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    • 2018
  • Estimating reliability of a non-repairable system using the degradation data, variance assumption such as homogeneity (constant) or heteroscedasticity (time-variant) could affect accuracy of reliability estimation. This paper showed reliability estimation and comparison results under normal conditions using accelerated degradation data obtained from destructive measurements, according to variance assumption of the data at each measurement time. Degradation data from three accelerated conditions with stress factors of temperature and humidity were used to estimate reliability. The $B_{10}$ lifetime was estimated as 1243.8 years by constant variance assumption, and 18.9 years by time-variant variance. And variance assumption provided different analysis results of important stresses to reliability. Thus, accurate assumption of variance at each measurement time is required when estimating reliability using degradation data of a non-repairable system.

A Study on the Life Characteristic of an Automotive Water-pump Bearing Using the Accelerated Test Method (가속시험법을 활용한 자동차용 워터펌프 베어링의 수명특성에 관한 연구)

  • Yang, Hui Sun;Shin, Jung Hun;Park, Jong Won;Sung, Baek Ju
    • Tribology and Lubricants
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    • v.31 no.2
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    • pp.35-41
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    • 2015
  • A water-pump located in the cooling area of a car circulates cooling water. A particular bearing element, known as a water-pump bearing, installed in the rotating part carries the entire load. The failure of this water-pump bearing has a direct impact on the failure of the automobile engine, and so securing its reliability is crucial. Several researchers have examined the design principles of the water-pump bearing, but there are no reports on the life characteristic of the bearing yet. Herein, we report the construction of test equipment to reproduce the spalling of the roller contact, which is the main failure mode of the chosen water-pump bearing. We chose the radial load as an accelerated stress factor and validated the failure mode by monitoring the surface defects. We conducted the accelerated life test after determining the accelerated stress level through a combination of finite element analysis and a preliminary test. In the life tests, we used an accelerometer to perform failure diagnosis. In the last stage of this study, we present a statistical reliability analysis. Thus, we fully estimated the shape parameter of the water-pump bearing, accelerating level on the load , and the lifetime (MTTF and B10 life) under real use conditions, and finally proposed an interval estimation value considering the uncertainty of the estimated value.

Effect of Repeated Laundry on Shrinkage Rate of Chainsaw Protective Pants (반복세탁이 산림작업복 하의의 수축률에 미치는 영향)

  • Jeong, Eung-Jin;Park, Su-Gyu;Han, Sang-Kyun;Cha, Du-Song
    • Journal of Korean Society of Forest Science
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    • v.108 no.3
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    • pp.341-348
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    • 2019
  • In order to reduce the safety risk of forestry operations, this research was conducted to examine the suitability of chainsaw protective pants after repeated laundering, testing four different products that are currently used in hand-held chainsaw operations. Laundering was repeated 10, 20, 30, 40, and 50 times. After washing, we measured the shrinkage ratio of 17 measurement positions mostly affecting the safety of forest operations and suggested the expected safety life cycle of chainsaw protective clothes. The results showed that most of the products have only one measurement position where the standard shrinkage ratio (<6%) was exceeded after 20 washings, and that the lateral direction of measurement positions shrank more than the vertical one. The numbers of repeated launderings and measurement positions were found to be significant factors influencing the shrinkage ratio (p<0.05). In the shrinkage rates for 17 measurement positions, there were significant correlations between five of the measurement positions (a, b, g, j, and n) and the number of repeated launderings (p<0.05). Therefore, the results suggest that about 10 months would be suitable for an adequate safety lifetime for chainsaw protective pants. The relationship between the number of repeated launderings and the measurement positions will be further analyzed in detail to examine the durability of chainsaw protective pants.

Economic Evaluation and Budget Impact Analysis of the Surveillance Program for Hepatocellular Carcinoma in Thai Chronic Hepatitis B Patients

  • Sangmala, Pannapa;Chaikledkaew, Usa;Tanwandee, Tawesak;Pongchareonsuk, Petcharat
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8993-9004
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    • 2014
  • Background: The incidence rate and the treatment costs of hepatocellular carcinoma (HCC) are high, especially in Thailand. Previous studies indicated that early detection by a surveillance program could help by down-staging. This study aimed to compare the costs and health outcomes associated with the introduction of a HCC surveillance program with no program and to estimate the budget impact if the HCC surveillance program were implemented. Materials and Methods: A cost utility analysis using a decision tree and Markov models was used to compare costs and outcomes during the lifetime period based on a societal perspective between alternative HCC surveillance strategies with no program. Costs included direct medical, direct non-medical, and indirect costs. Health outcomes were measured as life years (LYs), and quality adjusted life years (QALYs). The results were presented in terms of the incremental cost-effectiveness ratio (ICER) in Thai THB per QALY gained. One-way and probabilistic sensitivity analyses were applied to investigate parameter uncertainties. Budget impact analysis (BIA) was performed based on the governmental perspective. Results: Semi-annual ultrasonography (US) and semi-annual ultrasonography plus alpha-fetoprotein (US plus AFP) as the first screening for HCC surveillance would be cost-effective options at the willingness to pay (WTP) threshold of 160,000 THB per QALY gained compared with no surveillance program (ICER=118,796 and ICER=123,451 THB/QALY), respectively. The semi-annual US plus AFP yielded more net monetary benefit, but caused a substantially higher budget (237 to 502 million THB) than semi-annual US (81 to 201 million THB) during the next ten fiscal years. Conclusions: Our results suggested that a semi-annual US program should be used as the first screening for HCC surveillance and included in the benefit package of Thai health insurance schemes for both chronic hepatitis B males and females aged between 40-50 years. In addition, policy makers considered the program could be feasible, but additional evidence is needed to support the whole prevention system before the implementation of a strategic plan.

The Reliability Design Method According to the Experimental Study of Components and Materials of Railway Rail Fastening System (철도용 레일체결장치 부품.소재의 실험적 연구를 통한 신뢰성 설계 방안)

  • Kim, Hyo-San;Park, Joon-Hyung;Kim, Myung-Ryule;Park, Kwang-Hwa;Lee, Dal-Jae
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.2090-2100
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    • 2011
  • Railway rail fastening system is the critical device which gives big influences to not only the vehicle driving stability and the orbit's structural stability against the impulsive load, but also the noise vibration and the ride comfort. As a part of the low-carbon green growth, the importance of the railroad industry is getting highlights on its excellent energy-efficiency and eco-friendliness. However, so far the Korea's domestic rail fastening system technology is not so good and the technical reliance to abroad is very heavy. In this study, we conducted comparative analysis on the rail fastening system with new and used one of the same type. And those systems are imported by Seoul Metro and are being used by it. With this basis, we developed the components and the materials and then, established the durability assessment methods appropriate to the Korean domestic circumstances. And through the reliability qualification test on the 7 parts of the rail fastening system, we've improved the reliability and guaranteed the 15 years of service lifetime. ($B_{10}Life15$) Establishment and standardization of Reliability Standard on the parts of the rail fastening system such as anti-vibration pads, guide-plate, screw spike made it possible to perform the internationally fair assessment. And it is thought that we can satisfy the manufactures' and consumers' needs of cost-cutting and qualification security by shortening of assessment period on rail fastening system.

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A Study on Job Satisqaction of Health Ceuter nurses in Chunbuk Province. (전북지역 보건소 간호사의 직업만족도에 관한 조사연구)

  • Ryu Kwang Soo
    • Journal of Korean Public Health Nursing
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    • v.5 no.2
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    • pp.53-66
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    • 1991
  • The Purpose of this study is to provide the basic data necessary for the high level of nursing service and the efficiency plan of nurse's man power by analyzing job satisfaction level of public health services. The study population included all public health services(118) in health care center within Jeon Buk province. A Survey was conducted to collect data by a self-administered questionnaire from September I to December B, 1990. A Forty item questionnaire was designed to elicit data concerning how nurses feel about the factors of job satisfaction. All the data were analyzed by means of percentage, mean, anova, T-test, Pearsen's correlation coefficient. The Results of this study were summerized as follows. 1. General characteristics of PHN : age: $33.9\%\;20\~29$ years old education level: $52.6\%$ professional nursing college marital status: $75.5\%$ married religion: $50.5\%$ protestant clinical experience: $40.7\%$ no clinical experience public health nursing career: $47.9\%$ low 5years 2. Influencing factor of Job satisfaction desired duration of employment: $65\%$ needed duration, $18.3\%$ lifetime duration motives of employment: $40.8\%$ no special motive of employment desired organ of leave: $19.3\%$ public health clinic 3. Level of job satisfaction with job satisfaction components. The level of job satisfaction showed an average score 3.39 out of 5.0. Job prestige 4.09 was the highest among the components of Job satisfaction and was presented organizational requirement 3.69, Human relationship 3.66, task requirement 3.36, Autonomy 3.10, pay 2.46. 4. Level of job satisfaction with general characteristics. General characteristics(age, educational level, manital status, clinical experience, public health nursing carrier, duties, lincense and qualification) and job satisfaction was no relationship. 5. Level of job satisfaction with Influencing factor. Duration of desired employment (p<0.01) and motives of employment(p<0.001) was presented. 6. Relationship composing factor of job satisfaction and level of job satisfaction 6 components of job satisfaction was related all of job satisfaction. organizational requirement (r=0.93). Autonomy (r=0.93), Human relationship(r=0.92), task requirement (r=0.90), job prestige (r=0.83), pay (r=0.81)

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Effect of Diamond Abrasive Shape of CMP Conditioner on Polishing Pad Surface Control (CMP 컨디셔너의 다이아몬드 입자 모양이 연마 패드 표면 형상 제어에 미치는 영향)

  • Lee, Donghwan;Lee, Kihun;Jeong, Seonho;Kim, Hyungjae;Cho, Hanchul;Jeong, Haedo
    • Tribology and Lubricants
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    • v.35 no.6
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    • pp.330-336
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    • 2019
  • Conditioning is a process involving pad surface scraping by a moving metallic disk that is electrodeposited with diamond abrasives. It is an indispensable process in chemical-mechanical planarization, which regulates the pad roughness by removing the surface residues. Additionally, conditioning maintains the material removal rates and increases the pad lifetime. As the conditioning continues, the pad profile becomes unevenly to be deformed, which causes poor polishing quality. Simulation calculates the density at which the diamond abrasives on the conditioner scratch the unit area on the pad. It can predict the profile deformation through the control of conditioner dwell time. Previously, this effect of the diamond shape on conditioning has been investigated with regard to microscopic areas, such as surface roughness, rather than global pad-profile deformation. In this study, the effect of diamond shape on the pad profile is evaluated by comparing the simulated and experimental conditioning using two conditioners: a) random-shaped abrasive conditioner (RSC) and b) uniform-shaped abrasive conditioner (USC). Consequently, it is confirmed that the USC is incapable of controlling the pad profile, which is consistent with the simulation results.

The Effects of UBM and SnAgCu Solder on Drop Impact Reliability of Wafer Level Package

  • Kim, Hyun-Ho;Kim, Do-Hyung;Kim, Jong-Bin;Kim, Hee-Jin;Ahn, Jae-Ung;Kang, In-Soo;Lee, Jun-Kyu;Ahn, Hyo-Sok;Kim, Sung-Dong
    • Journal of the Microelectronics and Packaging Society
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    • v.17 no.3
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    • pp.65-69
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    • 2010
  • In this study, we investigated the effects of UBM(Under Bump Metallization) and solder composition on the drop impact reliability of wafer level packaging. Fan-in type WLP chips were prepared with different solder ball composition (Sn3.0Ag0.5Cu, and Sn1.0Ag0.5Cu) and UBM (Cu 10 ${\mu}m$, Cu 5 ${\mu}m$\Ni 3 ${\mu}m$). Drop test was performed up to 200 cycles with 1500G acceleration according to JESD22-B111. Cu\Ni UBM showed better drop performance than Cu UBM, which could be attributed to suppression of IMC formation by Ni diffusion barrier. SAC105 was slightly better than SAC305 in terms of MTTF. Drop failure occurred at board side for Cu UBM and chip side for Cu\Ni UBM, independent of solder composition. Corner and center chip position on the board were found to have the shortest drop lifetime due to stress waves generated from impact.

Design and Implementation of Routing Algorithms for Energy Efficiency in Sensor Network (센서네트워크의 에너지 효율성을 고려한 라우팅 알고리즘 설계 및 구현)

  • Jeong, Dae-In;Chea, Byong-Jin
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.10B
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    • pp.619-629
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    • 2005
  • In this paper, we propose energy-aware routing schemes which are simple enough to be applicable to the wireless sensor networks. The one hop upstream no de in direction of the base-station is determined in four different ways based on the energy information of neighboring nodes, which are obtainable via the process of self-organization of the network. The fair distribution of the energy consumption over all the possible routes to the base-station is one of the design objectives. Also, an alternate route search mechanism is proposed to cope with the situation in which no routing information is available due to lack of remaining energy of the neighboring nodes. The mechanism turns out to be a supplementary scheme to improve the energy efficiency. Lots of simulations are performed to examine the performance metrics such as the energy efficiency, throughput, network lifetime, and the transmission latency of the proposed schemes. Simulation results show the feasibility of the simple routing schemes for the sensor networks.