• YAKHAK HOEJI
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• v.42 no.3
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• pp.290-295
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• 1998

To optimize the formulation of acetaminophen liquid suppository, the effect of additives on the physicochemical properties of liquid suppository base was investigated. The physi cochemical properties of P 407/P 188 (15/15%) (abbreviated in 15/15) and P 407/P l88 (15/20%) (abbreviated in 15/20) were measured after the addition of following additives; 2.5% acetaminophen as an active ingredient, vehicle components (5% ethanol, 5% propylene glycol, 5% glycerin), preservatives (0.1% sodium benzoate, 0,1% methylparahydroxybenzoate, 0.1% propylparahydroxybenzoate) and 1% of sodium chloride as an ionic strength controlling agent. Poloxamer gel was prepared with three different buffer solutions (pH 1.2, 4.0 and 6.8) and the physicochemical properties, gelation temperature, gel strength and bioadhesive force, were determined. In the results, the effect of additives on the physicochemical properties was dependent on their bonding capacities including hydrogen bonding and cross-linking bonding. Because the hydrogen-bonding capacities of acetaminophen, ethanol and propylene glycol were smaller than that of poloxamer, the binding force of poloxamer gel became weak by their putting in between poloxamer gel. Therefore, the gelation temperature (15/15, $35.7^{\circ}C$ vs 37.0, 39.4 $38.2^{\circ}C$; 15/20, $29.2^{\circ}C$ vs 31.2, 32.0, $30.3^{\circ}C$) increased, and gel strength (15/15, 4.03 see vs 2.72, 2.08, 3.12sec; 15/20, 300g vs 50, 50, 200g) and bioadhesive force (15/15, $6.8{\times}10^2\;dyne/cm^2$ vs 3.2, 6.0, $6.0{\times}10^2\;dyne/cm^2$; 15/20, $97.3{\times}10^2\;dyne/cm^2$ vs 11.1, 89.5, $92.0{\times}10^2\;dyne/cm^2$) decreased. Furthermore, the binding force of poloxamer gel became strong due to the hydrogen-bonding capacities of glycerin and the cross-liking bonding of sodium salt. Then, the gelation temperature (15/15, 35.0, $32.1^{\circ}C$; 15/20, 26.0, $21.0^{\circ}C$) decreased, and gel strength (15/15, 6.51 see, 300g; 15/20, 500, 650g) and bioadhesive force (15/15, 7.2, $81.6{\times}10^2\;dyne/cm^2$; 15/20, 112.3, $309.2{\times}10^2\;dyne/cm^2$) increased. The effect of pH on the physicochemical properties of poloxamer gel was dependent on the ingredients with which the buffer solutions were prepared. Poloxamer gels prepared with pH 1.2 and 4.0 buffer solutions had the increasing gelation temperature (15/15, 37.5, $38.1^{\circ}C$; 15/20, 33.1, $34.0^{\circ}C$) and the decreasing gel strength (15/15, 2.98, 3.81sec; 15/20, 200, 200g) and bioadhesive force (15/15, $7.0{\times}10^2dyne/cm^2$; 15/20, $74.0{\sim}88.1{\times}10^2dyne/cm^2$) owing to HCl. Poloxamer gel prepared with pH 6.8 buffer solutions had the decreasing gelation temperature (15/15, $27.2^{\circ}C$; 15/20, $22.3^{\circ}C$) and the increasing gel strength (15/15, 400g; 15/20, 550g) and bioadhesive force (15/15, $207.0{\times}10^2dyne/cm^2$; 15/20, $215.0{\times}10^2dyne/cm^2$) due to the cross-linking bonding of $NaH_2PO_4\;and\;K_2HPO_4$.

• Journal of Korean Society of Transportation
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• v.27 no.4
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• pp.207-215
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• 2009

Generally, traffic accidents can be influenced by variables driving conditions including geometric, roadside design, and traffic conditions. Under the circumstance, homogeneous roadway segments were firstly identified using typical geometric variables obtained from field data collections in this study. These field data collections were conducted at highways located in several areas having various regional conditions for examples, outside metropolitan city; level and rolling rural areas. Due to many zero cells in crash database, a Zero Inflated Poisson model was used to develop crash prediction model to overestimated results in this study. It was found that EXPO, radius, grade, guardrail, mountainous terrain, crosswalk and bus-stop have statistically significant influence on vehicle to vehicle crashes at rural multi-lane roadway segments.

• Journal of Electrical Engineering and Technology
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• v.7 no.6
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• pp.971-976
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• 2012

A 150 kJ compact capacitive pulsed power system (CCPPS) capable of delivering electrical energy into an electrothermal chemical (ETC) gun on a vehicle has been studied. The CCPPS provides pulsed electrical energy into a capillary plasma injector which generates plasma of tens of thousands $^{\circ}K$ in temperature and has a nonlinear resistance depending on the current. The design requirements of the CCPPS are as follows: the maximum power of 250 MW, the pulse width of about 0.6 ms, the volume of no more than 0.5 cubic meter, the efficiency of energy transfer over 80 % and the repetition rate of 4~5 times per minute. The constructed CCPPS is composed of four 37.5 kJ capacitor bank modules in parallel to make a trapezoid pulse shape and to satisfy the design requirements. Each module is designed to achieve high reliability, safety, efficiency and energy density to endure severe operating conditions. The results of the performance test on the CCPPS using a 120 mm ETC gun are described.

• Journal of the Korean Society for Heat Treatment
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• v.16 no.4
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• pp.205-210
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• 2003

Various types of high strength steel sheets were usually used for improving the automobile safety and fuel efficiency by reducing the vehicle weight. The present study aimed to develop the TRIP (transformation induced plasticity) aided high-strength low carbon steel sheets by using a reverse transformation process. The 0.1C-4~8Mn steels were reverse-transformed by slow heating to intercritical temperature region and then furnace cooled to the room temperature. Granular type retained austenite was observed in 4Mn steel and lath type retained austenite was also observed in 6~8Mn steel. The results show that the 6Mn steel under reverse transformed at $625^{\circ}C$ for 6 hrs has maximum elongation up to 39%. The optimum strength-elongation combination was 3,888 ($kg/mm^2{\times}%$) when the 8Mn steel was reverse transformed at $625^{\circ}C$ for 12 h.

• Korean Journal of Remote Sensing
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• v.32 no.5
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• pp.483-497
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• 2016

Unmanned Aerial Vehicle (UAV) imagery are being assessed for analyzing within field spatial variability for agricultural precision management, because UAV imagery may be acquired quickly during critical periods of rapid crop growth. This study refers to the derivation of barley and wheat growth prediction equation by using UAV derived vegetation index. UAV imagery was taken on the test plots six times from late February to late June during the barley and wheat growing season. The field spectral reflectance during growing period for the 5 variety (Keunal-bori, Huinchalssal-bori, Saechalssal-bori, Keumkang and Jopum) were measured using ground spectroradiometer and three growth parameters, including plant height, shoot dry weight and number of tiller were investigated for each ground survey. Among the 6 Vegetation Indices (VI), the RVI, NDVI, NGRDI and GLI between measured and image derived showed high relationship with the coefficient of determination respectively. Using the field investigation data, the vegetation indices regression curves were derived, and the growth parameters were tried to compare with the VIs value.

• International Journal of Highway Engineering
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• v.8 no.1 s.27
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• pp.119-130
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• 2006

The behavior of continuously reinforced concrete pavement (CRCP) and the effect of the steel ratio on the behavior under moving wheel loads were investigated in this study. The CRCP sections having different steel ratios of 0.6, 0.7, and 0.8% were considered to evaluate the load transfer efficiency (LTE) at transverse cracks and to investigate the strains in CRCP when the system is subjected to moving vehicle loads. The LTEs were obtained by conducting the falling weight deflectometer (FWD) tests and the tests were performed at three different times of a day to find the curling effect due to the daily temperature changes in CRCP. The strains in the concrete slab and the bond braker layer of the CRCP system under moving vehicle loads were obtained using the embedded strain gages. The results of this study show that the LTEs at transverse cracks are very high and not affected by the time of testing and the steel ratio. The strains in CRCP under vehicle loads become smaller as the vehicle speed increases or as the wandering distance increases; however, the strains are not clearly affected by the steel ratio.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.6
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• pp.1851-1861
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• 2014

This study aims to calculate reliable sectional travel speeds with the consideration of the characteristics of the probe data collected in the interrupted traffic flow. First, in order to analysis the characteristics of the probe data, we looked into the distribution of the sectional travel times of each probe vehicle and compared the difference in the sectional travel speeds of each probe vehicle collected by DSRC. As a result, it is shown that outliers should be removed for the distribution of the sectional travel times. However, The comparison results show that the sectional travel speeds from the DSRC probe vehicles are not significantly different. Finally, based on the distribution characteristics of the sectional travel speeds of each probe vehicle and the representative values counted during a collection period, we drew the optimal outlier removal procedure and evaluated the estimation errors. The evaluation results showed that the DSRC sectional travel speeds were found to be similar to the observed values from actually running vehicles. On the contrary, in the case of the sectional travel speeds of intra-city bus, it was analyzed that they were less accurate than the DSRC sectional travel speeds. In the future, it will be necessary to improve BIS process and make use of the travel information on intra-city buses collected in real time to find various ways of applying it as traffic information.

• Korean Journal of Pharmacognosy
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• v.44 no.1
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• pp.83-90
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• 2013

The aim of this study was to evaluate the effect of hot water extract of peduncle obtained from Hovenia dulcis Thunb (HD) which is commercially developed for the protective effect on the alcoholic hepatotoxicity, on the endurance capacity for weight loaded forced swimming mice. The swimming times to exhaustion in mice fed 100 and 200 mg/kg HD for 2 weeks were prolonged 3.6 and 3.7 fold, and for 4 weeks 1.9 and 2.7 fold compared with each vehicle control ($42.8{\pm}20.5$ min and $67.7{\pm}47.8$ min, for 2 and 4 weeks), respectively. Blood biochemical parameters for ALT, AST, creatinine and BUN were not significantly different between from HD fed or control mice. Although HD fed mice swam over 2 fold longer time than vehicle control mice at 4 weeks, blood biomarkers of physical fatigue such as glucose, triglyceride and free fatty acid, lactate were not significant different and even tended to ameliorate. Hepatic lipid peroxidation and SOD activity did not significantly change in HD fed- and vehicle control exhausted swimming mice at 2 or 4 weeks. However, catalase activity in HD-fed mice was significantly increased in a dose-dependent manner compared with vehicle control mice. The present study indicates that HD improved physical fatigue and exercise performance in mice. Therefore, it has a potential for the pharmacological effect of anti-fatigue.

• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.6
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• pp.1006-1012
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• 2010

For the autonomous navigation of an unmanned ground vehicle in the rough terrain and combat, the dust environment should necessarily be overcome. Therefore, we propose a robust obstacle detection methodology using laser range sensor and radar. Laser range sensor has a good angle and distance accuracy, however, it has a weakness in the dust environment. On the other hand, radar has not better the angle and distance accuracy than laser range sensor, it has a robustness in the dust environment. Using these characteristics of laser range sensor and radar, we use laser range sensor as a main sensor for normal times and radar as a assist sensor for the dust environment. For fusion of laser range sensor and radar information, the angle and distance data of the laser range sensor and radar are separately transformed to the angle and distance data of virtual range sensor which is located in the center of the vehicle. Through distance comparison of laser range sensor and radar in the same angle, the distance data of a fused virtual range sensor are changed to the distance data of the laser range sensor, if the distance of laser range sensor and radar are similar. In the other case, the distance data of the fused virtual range sensor are changed to the distance data of the radar. The suggested methodology is verified by real experiment.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.109-114
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• 2008

This paper presents the development status of a subscale precooled turbojet engine "S-engine" for the hypersonic cruiser and space place. S-engine employs the precooled-cycle using liquid hydrogen as fuel and coolant. It has $23cm{\times}23cm$ of rectangular cross section, 2.6 m of the overall length and about 100 kg of the target weight employing composite materials for a variable-geometry rectangular air-intake and nozzle. The design thrust and specific impulse at sea-level-static(SLS) are 1.2 kN and 2,000 sec respectively. After the system design and component tests, a prototype engine made of metal was manufactured and provided for the system firing test using gaseous hydrogen in March 2007. The core engine performance could be verified in this test. The second firing test using liquid hydrogen was conducted in October 2007. The engine, fuel supplying system and control system for the next flight test were used in this test. We verified the engine start-up sequence, compressor-turbine matching and performance of system and components. A flight test of S-engine is to be conducted by the Balloon-based Operation Vehicle(BOV) at Taiki town in Hokkaido in October 2008. The vehicle is about 5 m in length, 0.55 m in diameter and 500 kg in weight. The vehicle is dropped from an altitude of 40 km by a high-altitude observation balloon. After 40 second free-fall, the vehicle pulls up and S-engine operates for 60 seconds up to Mach 2. High altitude tests of the engine components corresponding to the BOV flight condition are also conducted.