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Development and efficiency evaluation of 30kW scale syngas cogeneration system (30kW 급 합성가스 열병합 시스템 개발 및 효율 성능평가)

  • Park, Il-Gun;Kim, Sang-Tae;Noh, Gwi-Sung
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.4
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    • pp.1427-1433
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    • 2019
  • In this paper, Gas engine was tested for the energy of synthesis gas. As excess air ratio increase 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6 in 1800 rpm and synthesis gas, thermal efficiency generally decrease and power generation was 34 kWm at λ 1.4. And excess air ratio increase 1, 1.1, 1.2, 1.3, 1.4 in power generation 34 kWm, thermal efficiency generally increase 34.2%, 36.9%, 37.2%, 37.4%, 38.1%. Total efficiency through power generation consumes 38.7 kg/h of fuel at 30 kWe load and recovers 57.3% of waste heat by recovering 57.3 kW of waste heat through 32.1% power generation efficiency and heat recovery from cooling water and exhaust gas. The total efficiency was 85.8%.

Asiatic Acid Promotes p21WAF1/CIP1 Protein Stability through Attenuation of NDR1/2 Dependent Phosphorylation of p21WAF1/CIP1 in HepG2 Human Hepatoma Cells

  • Chen, Jin-Yuan;Xu, Qing-Wen;Xu, Hong;Huang, Zong-Hai
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.963-967
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    • 2014
  • Previous studies have suggested anti-tumor effects of asiatic acid in some human cancer cell lines. This agent is reported to increase the levels of $p21^{WAF1/CIP1}$ in human breast cancer cell lines. However, the molecular mechanisms have not been established. Here we report that asiatic acid up-regulates $p21^{WAF1/CIP1}$ protein expression but not the level of $p21^{WAF1/CIP1}$ mRNA in HepG2 human hepatoma cells. Furthermore, we found that the asiatic acid induced increase of $p21^{WAF1/CIP1}$ protein was associated with decreased phosphorylation (ser-146) of $p21^{WAF1/CIP1}$. Knockdown of NDR1/2 kinase, which directly phosphorylates $p21^{WAF1/CIP1}$ protein at ser-146 and enhances its proteasomal degradation, increased the levels of $p21^{WAF1/CIP1}$ protein and eliminated the regulation of $p21^{WAF1/CIP1}$ stability by asiatic acid. At the same time, the expression of NDR1/2 kinase decreased during treatment with asiatic acid in HepG2 cells. Moreover, asiatic acid inhibited the proliferation of HepG2 cells, this being attenuated by knockdown of $p21^{WAF1/CIP1}$. In conclusion, we propose that asiatic acid inhibits the expression NDR1/2 kinase and promotes the stability of $p21^{WAF1/CIP1}$ protein through attenuating NDR1/2 dependent phosphorylation of $p21^{WAF1/CIP1}$ in HepG2 cells.

EMBEDDING OF WEIGHTED $L^p$ SPACES AND THE $\bar{\partial}$-PROBLEM

  • Cho, Hong-Rae
    • East Asian mathematical journal
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    • v.19 no.1
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    • pp.73-80
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    • 2003
  • Let D be a bounded domain in $\mathbb{C}^n$ with $C^2$ boundary. In this paper, we prove the following inequality $${\parallel}u{\parallel}_{p_2,{\alpha}_2}{\lesssim}{\parallel}u{\parallel}_{p_1,{\alpha}_1}+{\parallel}\bar{\partial}u{\parallel}_{p_1,{\alpha}_1+p_1}/2$$, where $1{\leq}p_1{\leq}p_2<\infty,\;{\alpha}_j>0,(n+{\alpha}_1)/p_1=(n+{\alpha}_1)/p_1=(n+{\alpha}_2)/p_2$, and $1/p_2{\geq}1/p_1-1/2n$.

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CYP1A1 (Ile462Val), CYP1B1 (Ala119Ser and Val432Leu), GSTM1 (null), and GSTT1 (null) Polymorphisms and Bladder Cancer Risk in a Turkish Population

  • Berber, Ufuk;Yilmaz, Ismail;Yilmaz, Omer;Haholu, Aptullah;Kucukodaci, Zafer;Ates, Ferhat;Demirel, Dilaver
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3925-3929
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    • 2013
  • We aimed to investigate bladder cancer risk with reference to polymorphic variants of cytochrome p450 (CYP) 1A1, CYP1B1, glutathione S-transferase (GST) M1, and GSTT1 genes in a case control study. Polymorphisms were examined in 114 bladder cancer patients and 114 age and sex-matched cancer-free subjects. Genotypes were determined using allele specific PCR for CYP1A1 and CYP1B1 genes, and by multiplex PCR and melting curve analysis for GSTM1 and GSTT1 genes. Our results revealed a statistically significant increased bladder cancer risk for GSTT1 null genotype carriers with an odds ratio of 3.06 (95% confidence interval=1.39-6.74, p=0.006). Differences of CYP1A1, CYP1B1 and GSTM1 genotype frequencies were not statistically significant between patients and controls. However, the specific combination of GSTM1 null, GSTT1 null, and CYP1B1 codon 119 risk allele carriers and specific combination of GSTM1 present, GSTT1 null, and CYP1B1 432 risk allele carriers exhibited increased cancer risk in the combined analysis. We did not observe any association between different genotype groups and prognostic tumor characteristics of bladder cancer. Our results indicate that inherited absence of GSTT1 gene may be associated with bladder cancer susceptibility, and specific combinations of GSTM1, GSTT1 and CYP1B1 gene polymorphisms may modify bladder cancer risk in the Turkish population, without any association being observed for CYP1A1 gene polymorphism and bladder cancer risk.

Studies on Milk Protein by Zone Electrophoresis (대전기영동법(帶電氣泳動法)에 의한 유청단백질(乳淸蛋白質)에 관(關)한 연구(硏究))

  • Cho, Duk-Bong;Nam, Hyun-Keun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.5 no.1
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    • pp.25-30
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    • 1976
  • In this investigation, the physico-chemical properties of Korean cattles milk and Holstein cows milk are studied. The results of the milk -protein of F-1, F-2, and F-4 hybrid are interested in this studied. 1. The physico-chemical properties of Korean cattle and Holstein cows milk is summarized at Table 1, Table 2. 2. The electrophoretic milk protein fraction of Korean cattle is identified : Lactoalbumin 1.74mg%. Alpha-1 globulin 1.19mg%, Alpha-2 globulin 0.68mg%, Beta-globulin 2.57mg%, Gamma-globulin 0.93mg%. 3. The electrophoretic milk protein fraction of Holstein cow : Lactoalbumin 1.23mg%, Alpha-1 globulin 0.93mg%, Alpha-2 globulin 0.86mg%, Bata-globulin 2.56mg%, Gamma-globulin 1.74mg% have been identified. 4. The electrophoretic milk protein fraction of hybrid F-1, F-2, and F-4 between Korean cattle(female) and Holstein(male) is obtained the following : F-1 hybrid : Lactoalbumin 1.38mg%, Alpha-1 globulin 1.58mg%, Alpa-2 globulin 2.46mg%, Beta-globulin 1.39mg%. F-2 hybrid : Lactoalbumin 1.57mg%, Alpha-1 globulin 1.74mg%, Alpha-2 globulin 2.19mg%, Beta-globulin 1.74mg%. F-4 hybrid : Lactoalbumin 2.46mg%, Alpha-1 globulin 1. 24mg%, Alpha-2 globulin 1.57㎎%, Beta-globulin 1.74mg%.

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Milt Properties and Spermatozoa Structure of Filefish(Thamnaconus modestus) (말쥐치(Thamnaconus modestus) 정액의 특성과 정자의 미세구조)

  • Le, Minh Hoang;Lim, Han-Kyu;Min, Byung-Hwa;Kim, Sung-Yeon;Chang, Young-Jin
    • Development and Reproduction
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    • v.11 no.3
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    • pp.227-233
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    • 2007
  • The milt properties of filefish(Thamnaconus modestus) included physical properties of sperm and biochemical properties of seminal plasma. The physical properties of milt were $0.3{\pm}0.1\;mL{\cdot}fish^{-1}$ in sperm volume, $2.6{\pm}0.1{\times}10^7\;spermatozoa{\cdotg}mL^{-1}$ in sperm concentration and $73.3{\pm}6.7$ in spermatocrit. The biochemical properties of seminal plasma contained $9.8{\pm}0.9\;mmol{\cdot}L^{-1}$ potassium, $164.0{\pm}4.0\;mmol{\cdot}L^{-1}$ sodium, $151.0{\pm}1.2\;mmol{\cdot}L^{-1}$ chloride, $14.9{\pm}0.6\;mg{\cdot}dL^{-1}$ calcium, $7.2{\pm}0.1\;mg{\cdot}dL^{-1}$ magnesium, $1.0\;mg{\cdot}dL^{-1}$ glucose, $0.1\;g{\cdot}dL^{-1}$ total protein and $1.0\;mg{\cdot}dL^{-1}$ total lipid. The osmolality and pH of seminal plasma were $322.8{\pm}2.8\;mOsmol{\cdot}kg^{-1}$ and $7.7{\pm}0.1$, respectively. The spermatozoon of filefish consisted of three parts: head without acrosome, mid-piece with five mitochondria and flagellum with "9+2" pattern. The head of spermatozoon in longitudinal section was horseshoe-shaped, and $1.3{\sim}1.6\;{\mu}m$ long and $1.0{\sim}1.3\;{\mu}m$ wide.

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Short-Term Effect of Cattle Slurry Application on Reed Canarygrass (Phalaris arundinacea L.) in Uncultivated Rice Paddy (유휴 논토양에서 Reed Canarygrass(Phalaris arundinacea L.) 에 대한 액상구비의 단기시용효과)

  • 조익환;이주삼;안종호
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.18 no.3
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    • pp.205-216
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    • 1998
  • In order to investigate the short-term effect of cattle slurry N application on dry matter yield of reed canarygrass(Phalaris arundinacea L.) in uncultivated rice paddy during the harvested years in 1993~1995. Annual cattle slurry N was applied at the levels of 0, 90, 180, 270 and 360 kg $ha^{-1}$ in 3 cuttings, 0, 120, 240, 360 and 480 kg $ha^{-1}$ in 4 cuttings, and 0, 150, 300, 450 and 600 kg $ha^{-1}$ in 5 cutting, respectively. The results were summarized as follows; 1. The dry matter yields of all cutting frequencies in 1993 were higher than in other harvested years. 2. Significantly higher dry matter yields were obtained as 13.10 tons $ha^{-1}$ at level of 360 kg $ha^{-1}\;yr^{-1}$ in 3 cuttings, 12.50-12.83 tons $ha^{-1}$ at levels of 360-480kg $ha^{-1}\;yr^{-1}$ in 4 cuttings, and 12.52-12.56 tons $ha^{-1}$at levels of 450-600 kg $ha^{-1}$ $yr^{-1}$in 5 cuttings, respectively. 3. Efficiency of dry matter production(kg DM $kg^{-1}$ N) to cattle slurry N application tended to decrease with higher levels of cattle slurry N application and cutting frequencies. Higher efficiencies of dry matter production to cattle slurry N application were obtained as 15.2 kg at N level of 90 kg $ha^{-1}\;yr^{-1}$in 3 cuttings, 19.8 kg at level of 120 kg $ha^{-1}\;yr^{-1}$ in 4 cuttings, and 10.0 kg at level of 150 kg $ha^{-1}\;yr^{-1}$ in 5 cuttings, respectively. 4. The highest relative yields(RY) in different cutting frequency were 38.1% for 2nd cut in 3 cuttings, 41.8% for 3rd cut in 4 cuttings, and 30.1% for 4th cut in 5 cuttings, respectively. 5. The estimated ranges of marginal dry matter yield(Ymar.) were 11.5~12.1 tons $ha^{-1}$ at the ranges of economic N level of 261.0~304.6 kg $ha^{-1}\;$yr^{-1}$ in 3 cuttings, 10.4~11.5 tons $ha^{-1}$ at the ranges of economic N level of 205~302.9 kg $ha^{-1}\;yr^{-1}$ in 4 cuttings, and 11.1~11.6 tons $ha^{-1}$ at the ranges of economic N level of 303.8~354.4 kg $ha^{-1}$ 5 cuttings, respectively. 6. Ranges of economic slurry N level(Necon.) in all cuts were 67.9~95.0 kg $ha^{-1}$ in 3 cuttings, 14.3~119.8 kg $ha^{-1}$in 4 cuttings, and 50.9-125.2 kg $ha^{-1}$ in 5 cutting, respectively. 7. The 3 cuttings per annum was a proper cutting frequency for the increase in dry matter production of reed canarygrass using uncultivated rice paddy.

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Relevance of Serum Vitamin D and Indices Related To Cardiovascular Disease Among Korean Adults (한국 성인의 혈청 비타민 D 수준과 심혈관 질환 관련 지표와의 관련성)

  • Kim, Han-Soo;Ryu, So-Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.365-374
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    • 2018
  • This study investigated the relationship between Vitamin D levels and indices related to cardiovascular disease in Korean adults aged ${\geq}19years$. The data for analysis were obtained from the sixth Korea National Health Nutrition Examination Survey in 2013 and 2014. The results showed that the incidence of Vitamin D deficiency was 73.1% among Korean adults and that indices related to cardiovascular disease showed an increasing trend (55.6% of Korean adults). The relationship between Vitamin D levels and indices related to cardiovascular disease with controlled physical activity status was also studied. The odds ratios (ORs) for age were 1.72 for the 4-62 years age group (95% CI, 1.53-1.93) and 2.05 for the ${\geq}65years$ age group (95% CI, 1.71-2.45). For blood pressure, the OR for pre-hypertension was 1.30 (95% CI, 1.15-1.47) and that for hypertension was 1.31 (95% CI, 1.11-1.54). For body mass index (BMI), the OR was 1.36 (95% CI, 1.11-1.66) and that for waist circumference (WC) was 1.36 (95% CI, 1.11-1.66). For fasting blood sugar (FBS), the OR for impaired fasting glucose (IFG) was 1.37 (95% CI, 1.21-1.55) and that for diabetes mellitus (DM) was 1.31 (95% CI, 1.05-1.65). The OR for total cholesterol (TC) was 1.30 (95% CI, 1.11-1.52) and that for triglycerides (TG) was 1.20 (95% CI, 1.04-1.37) in Korean adults. There was a significant relationship between Vitamin D and indices related to cardiovascular disease in Korean adults with respect to age, blood pressure, FBS, BMI, TC and TG. Confirmation of a causal relationship between Vitamin D and indices related to cardiovascular disease may require further research consisting of more systematic cohort studies.