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검색결과 4,198건 처리시간 0.025초

다엽제한기 소조사면의 6 MV 광자선 출력선량계수 (The Output Factor of Small Field in Multileaf Collimator of 6 MV Photon Beams)

  • 이호준;최태진;오영기;전경수;이용희;김진희;김옥배;오세안;김성규;예지원
    • 한국의학물리학회지:의학물리
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    • 제25권1호
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    • pp.15-22
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    • 2014
  • 종양부위의 입체적이고 선택적인 치료가 가능해 임상표적부피(clinical target vlume, CTV)에 높은 선량으로 집중조사하고 부작용을 현저히 줄이는 세기조절방사선치료는 치료예후를 향상시키고 있다. 방사선세기조절 치료는 MLC의 개방면적과 개방시간으로 조사면내 플루언스를 조정하므로 소형조사면의 선량이 누적되어 원하는 선량이 조사하게 된다. 따라서 소형조사면과 계층형 조사면의 출력선량계수의 정확성은 곧 Portal MU 결정에 정확성을 더할 수 있고, 종양에 조사되는 선량의 정확성을 향상할 수 있으므로, 이 연구는 Clinac Ex (Varian) $3{\times}3cm^2$에서 $0.5{\times}0.5cm^2$까지 조사면을 선정하였고 방사선은 6 MVX선의 소형조사면의 출력선량계수를 평가하였다. 조사면은 다엽제한기를 $40{\times}40cm^2$로 개방하고 Collimator jaw를 이용한 것과 Collimator를 $10{\times}10cm^2$로 고정하고 다엽제한기에 의한 조사면으로 구분하여 출력선량계수가 결정되었다. 검출기는 유효체적이 $0.01cm^3$이고 내경 2 mm인 CC01 (Scanditronix-Wellope)이온전리함과 SFD 다이오드 검출기(0.6 mmØ, $500{\mu}m$ 두께, Scanditronix-Wellope)와 다이아몬드 검출기(T60003, PTW)와 X-Omat film을 사용하였다. 결과는 다엽제한기 조사면의 출력선량계수는 $3{\times}3cm^2$에서 $0.899{\pm}0.0106$, $2{\times}2cm^2$에서 $0.855{\pm}0.0106$, $1{\times}1cm^2$에서 $0.764{\pm}0.0082$, $0.5{\times}0.5cm^2$에서 $0.602{\pm}0.0399$를 얻었다. Jaw를 $10{\times}10cm^2$로 고정하고 다엽제한기의 조사면의 출력계수는 MLC를 $40{\times}40cm^2$에 jaw에 의한 소형조사면의 것보다 최대 3.8% 높게 나타남을 확인하였다. 따라서 세기조절방사선치료 TPS에는 collimator jaw 보다 다엽제한기 조사면 크기의 출력선량계수가 설정되는 것이 중요함을 의미한다.

흰목이 균사체 형질전환 및 세포독성의 변화 (Genetic Transformation of the Mycelia of Tremella fuciformis and Changes of Cytotoxicity)

  • 신동일;박희성
    • 한국균학회지
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    • 제41권4호
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    • pp.287-291
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    • 2013
  • 흰목이는 고등 담자균류로서 효모와 유사한 분생포자(yeast-like conidia: YLC)가 출아법에 의하여 번식하는 특징을 지닌다. 본 연구에서는 hph 유전자를 지니는 pCambia 1300 plasmid를 Agrobacterium 이용 YLC 형질전환을 수행하였다. 그 결과 NaOH 처리가 이루어진 YLC 세포를 이용하는 경우에서만 형질전환이 가능하였으며 평균 $1.0{\times}10^6$ YLC 세포들로부터 40-50 형질전환체를 생산할 수 있었다. T-DNA 삽입은 PCR에 의하여 확인되었다. 형질전환체의 메탄올추출액은 암세포주인 SKOV-3에 대한 다양한 수준의 독성이 측정되었다.

Effects of Film Formation Conditions on the Chemical Composition and the Semiconducting Properties of the Passive Film on Alloy 690

  • Jang, HeeJin;Kwon, HyukSang
    • Corrosion Science and Technology
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    • 제5권4호
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    • pp.141-148
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    • 2006
  • The chemical composition and the semiconducting properties of the passive films formed on Alloy 690 in various film formation conditions were investigated by XPS, photocurrent measurement, and Mott-Schottky analysis. The XPS and photocurrent spectra showed that the passive films formed on Alloy 690 in pH 8.5 buffer solution at ambient temperature, in air at $400^{\circ}C$, and in PWR condition comprise $Cr_2O_3$, $Cr(OH)_3$, ${\gamma}-Fe_2O_3$, NiO, and $Ni(OH)_2$. The thermally grown oxide in air and the passive film formed at high potential (0.3 $V_{SCE}$) in pH 8.5 buffer solution were highly Cr-enriched, whereas the films formed in PWR condition and that formed at low potential (-0.3 $V_{SCE}$) in pH 8.5 buffer solution showed relatively high Ni content and low Cr content. The Mott-Schottky plots exhibited n-type semiconductivity, inferring that the semiconducting properties of the passive films formed on Alloy 690 in various film formation conditions are dominated by Cr-substituted ${\gamma}-Fe_2O_3$. The donor density, i.e., concentration of oxygen vacancy, was measured to be $1.2{\times}10^{21}{\sim}4.6{\times}10^{21}cm^{-3}$ and lowered with increase in the Cr content in the passive film.

Investigation of the Supercritical Fluids as an Insulating Medium for High Speed Switching

  • Shon, Chae-Hwa;Song, Ki-Dong;Oh, Yeon-Ho;Oh, Ho-Seok
    • Journal of Electrical Engineering and Technology
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    • 제11권6호
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    • pp.1783-1786
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    • 2016
  • The paper investigates the insulation properties of the supercritical $CO_2$ ($SCCO_2$) fluid as an insulating medium for electrical apparatuses. The insulating material is crucial for electrical apparatuses and $SF_6$ gas has been widely used for high power electrical apparatuses. There have been many research efforts to develop substituents for $SF_6$ gas because of high global warming potential. We obtained above 350 kV/mm insulation strength with 12.0 MPa $SCCO_2$. The positive and negative IEC standard pulses are applied between two 10 mm diameter spherical electrodes. The insulation strength of $SCCO_2$ is at least 2.5 times higher than that of $CO_2$ gas at 6.0MPa. The insulation strength of $SCCO_2$ fluid is about 10 times higher than that of $SF_6$ at 0.5MPa which is the ordinary operating pressure of electrical switchgears. Using the result, we expect that the time for switching and dielectric recovery could be reduced using $SCCO_2$ fluid as an insulating medium.

수중의 Pyrene, Chrysene 및 Benzo[a]pyrene의 광분해(II) (Photodegradation of Pyrene, Chrysene and Benzo[a]pyrene in Water (II))

  • 감상규;김지용;주창식;이민규
    • 한국환경과학회지
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    • 제12권7호
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    • pp.775-782
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    • 2003
  • The photodegradations of pyrene, chrysene and benzo[a]pyrene that were similar in structure among polycyclic aromatic hydrocarbons (PAHs) were investigated with a low-pressure mercury lamp(the wavelength of 253.7 nm and UV output of 1.35${\times}$10$\^$-3/J/s). The optimum concentrations of TiO$_2$ and H$_2$O$_2$ on the photodegradation of pyrene, chrysene and benzo[a]pyrene were 1 g/L and 1.5${\times}$10$\^$-3/ M, respectively. By these optimum concentrations, their rates increased with increasing the concentration of TiO$_2$ and H$_2$O$_2$ because the amounts of OH radical formed increased, but for the higher concentrations than the optimum, their rates decreased with increasing those concentrations because the white turbidity phenomena occurs in case of TiO$_2$ and H$_2$O$_2$ acts as an OH radical inhibitor. The photodegradation rates among the photodegradation processes such as UV, UV/TiO$_2$, UV/H$_2$O$_2$, and UV/H$_2$O$_2$/TiO$_2$ decreased in the following sequences.: UV/H$_2$O$_2$/TiO$_2$> UV/H$_2$O$_2$> UV/TiO$_2$> UV.

수용성 전해액을 사용하는 하이브리드 전기화학 축전기 (A Hybrid Electrochemical Capacitor Using Aqueous Electrolyte)

  • 김종휘;진창수;신경희;이미정
    • 전기화학회지
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    • 제6권2호
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    • pp.153-157
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    • 2003
  • 전기이중층 축전용량(electric double layer capacitance)과 유사축전용량(pseudo-capacitance)을 함께 갖는 하이브리드 전기화학 축전기에 대한 연구를 수행하였다. 양극은 $Ni(OH)_2$ 활성탄소가 복합된 전극을 사용하였으며 음극은 활성탄소를 활물질로 사용하므로써 비대칭 전극 구조를 갖는다. 셀 실험을 위하여 $5\times5cm^2$ 크기인 전극을 제작 사용하였다. Cyclic voltammetry측정 및 교류 임피던스 측정실험을 통하여 각각의 셀들이 갖는 전기화학적 거동을 조사하였고 충 방전 실험을 통하여 양극과 음극의 최적 질량비를 조사하였다.

메틸 라디칼과 산소 분자 반응에 관한 충격관 연구 (Shock Tube Study on the Reaction of Methyl Radical with Molecular Oxygen)

  • 신권수
    • 대한화학회지
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    • 제39권10호
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    • pp.769-775
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    • 1995
  • 메틸 라디칼과 산소 분자 사이의 반응 속도를 입사 충격파를 이용하여 1390부터 2250k 온도범위 및 1.5에서 5.3mol/$m^3$ 밀도 범위에서 213.9nm 파장에서의 메틸 라디칼의 흡수 스펙트럼을 측정하여 고찰하였다. 메틸 라디칼을 생성하기 위한 원천 분자로는 azomethane이 사용되었다. 실험 결과 $CH_3 + O_2{\rightarrow}CH_2O + OH$ 반응의 속도상수는 $k_2=1.35{\times}10^{12}\;exp( - 5900 K/T)\;cm^3 mol^{-1}s^{-1}$ 같이 표현할 수 있었다.

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Corrosive Wear of Alloy 690 Tubes in Alkaline Water

  • Hong, Seung Mo;Jang, Changheui;Kim, In Sup
    • Corrosion Science and Technology
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    • 제8권3호
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    • pp.126-131
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    • 2009
  • The interaction between wear and corrosion can significantly increase total material losses in water chemistry environment. The corrosive wear tests of a PWR steam generator tube material (Alloy 690) against the anti vibration bar material (409 SS) were performed at room temperature. The tests were performed in alkaline water chemistry conditions. NaOH solution was selected for test condition to investigate the corrosive wear effect of steam generator tube material in alkaline pH condition without other factors. The flow induced vibration can caused tube damage and the corrosion can be occurred by water chemistry. The test results showed that, in the alkaline solution at pH 13.9, the corrosion current density was increased about ten times than that in the distilled water. And wear rate at pH 13.9 was increased about ten times from that at neutral condition. However, the wear rate was decreased with time. The decrease would be attributed to the change in roughness of specimen or sub-layer of the worn surface with time. From microstructure observation, severe abrasive shape and several wear debris were found. From those results, it could infer that the oxide film on Alloy 690 changed to easily breakable one in the alkaline water, and then abrasion with corrosion became the main wear mechanism.

Antioxidant Activity from the Stem Bark of Albizzia julibrissin

  • Jung, Mee-Jung;Chung, Hae-Young;Kang, Sam-Sik;Choi, Jin-Ho;Bae, Kae-sun;Choi, Jae-Sue
    • Archives of Pharmacal Research
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    • 제26권6호
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    • pp.458-462
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    • 2003
  • The antioxidant activity of the stem bark from Albizzia julibrissin was evaluated for its potential to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, to inhibit the generation of the hydroxyl radical ($\cdot OH$), total reactive oxygen species (ROS) and to scavenge authentic peroxynitrites ($ONOO^{-}$). The methanol extract of A. julibrissin exhibited strong antioxidant activity in the tested model systems. Therefore, it was further fractionated using several solvents. The antioxidant activity of the individual fractions were in the order of ethyl acetate (EtOAc) > n-butanol (n-BuOH) > dichloromethane ($CH_2 CI-2$) > and water ($H_2O$). The ethyl acetate soluble fraction, which exhibited strong antioxidant activity, was further purified by repeated silicagel, Sephadex LH-20 and RP-18 gel column chromatography. Sulfuretin (1) and 3 ,4 ,7-trihydroxyflavone (2) were isolated as the active principles. Compounds 1 and 2 exhibited good activity in all tested model systems. Compound 1 exhibited five times more inhibitory activity on the total ROS than Trolox. Compound 2 showed six times stronger DPPH radical scavenging activity than L-ascorbic acid. These results show the possible antioxidant activity of the A. julibrissin crude extract and its major constituents.

A Study on Urban Change Detection Using D-DSM from Stereo Satellite Data

  • Jang, Yeong Jae;Oh, Kwan Young;Lee, Kwang Jae;Oh, Jae Hong
    • 한국측량학회지
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    • 제37권5호
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    • pp.389-395
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    • 2019
  • Unlike aerial images covering small region, satellite data show high potential to detect urban scale geospatial changes. The change detection using satellite images can be carried out using single image or stereo images. The single image approach is based on radiometric differences between two images of different times. It has limitations to detect building level changes when the significant occlusion and relief displacement appear in the images. In contrast, stereo satellite data can be used to generate DSM (Digital Surface Model) that contain information of relief-corrected objects. Therefore, they have high potential for the object change detection. Therefore, we carried out a study for the change detection over an urban area using stereo satellite data of two different times. First, the RPC correction was performed for two DSMs generation via stereo image matching. Then, D-DSM (Differential DSM) was generated by differentiating two DSMs. The D-DSM was used for the topographic change detection and the performance was checked by applying different height thresholds to D-DSM.