The coal wall, gob-side backfill, and gangues in goaf, constitute the support system for Gob-side entry retaining (GER) in coal mines. Reasonably allocating and utilizing their bearing capacities are key scientific and technical issues for the safety and economic benefits of the GER technology. At first, a mechanical model of GER was established and a governing equation for coordinated bearing of the coal-backfill-gangue support system was derived to reveal the coordinated bearing mechanism. Then, considering the bearing characteristics of the coal wall, gob-side backfill and gangues in goaf, their quantitative design methods were proposed, respectively. Next, taking the No. 2201 haulage roadway serving the No. 7 coal seam in Jiangjiawan Mine, China, as an example, the design calculations showed that the strains of both the coal wall and gob-side backfill were larger than their allowable strains and the rotational angle of the lateral main roof was larger than its allowable rotational angle. Finally, flexible-rigid composite supporting technology and roof cutting technology were designed and used. In situ investigations showed that the deformation and failure of surrounding rocks were well controlled and both the coal wall and gob-side backfill remained stable. Taking the coal wall, gob-side backfill and gangues in goaf as a whole system, this research takes full consideration of their bearing properties and provides a quantitative basis for design of the support system.