The purpose of this study is to review a variety of e-learning use in medical education, and to analyze the e-learning related research in medical education, finally to discuss possibilities and limitations of e-learning in future. Subjects of this research are 46 papers published in Korean Medical Database, PubMed, MEDLIS, RISS4U. Content analysis of 46 papers have been conducted based on the period of research, research methods, research subjects, study personnel, effectiveness. The results are as follows. First, various e-learning, such as hyper-media, simulation-based medical education (SBME), game-based learning, web-based learning, computer-based test (CBT) are implemented in medical education. Second, 35 research (76.1%) has verified the positive effect of e-learning. Third, in the case of Korean studies, experimental studies (46.2%) in a short period (46.2%) of 50-100 people (42.3%) to take the most. As a result, it is reported a lack of theoretical discussion and insight on e-learning compared to foreign research. Educational paradigms are currently shifting from off-line to on-line, from traditional classroom lecture to e-learning. But e-learning is not a substitution to traditional teaching, but a matter of choice. The choice is up to medical professors and students.