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Case Report of the Pityriasis Rosea Patient with Pruritus Treated by Korean Medicine Treatment alone

소양감이 동반된 장미색 비강진 환자의 한방단독치료 보고

  • Lee, Kyoungeun (College of Korean Medicine, Woosuk University) ;
  • Kim, Jungpil (College of Korean Medicine, Woosuk University) ;
  • Jeong, Seonhyung (College of Korean Medicine, Woosuk University) ;
  • Ahn, Joon (Misoro Oriental Clinic) ;
  • Jeong, Hyein (Department of Preventive Medicine, College of Korean Medicine, Woosuk University) ;
  • Kim, Kyounghan (Department of Preventive Medicine, College of Korean Medicine, Woosuk University) ;
  • Jang, Insoo (Department of Internal Medicine, College of Korean Medicine, Woosuk University) ;
  • Choi, Yoomin (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Woosuk University) ;
  • Oh, Yongtaek (Department of Diagnostic, College of Korean Medicine, Woosuk University)
  • 이경은 (우석대학교 한의과대학) ;
  • 김정필 (우석대학교 한의과대학) ;
  • 정선형 (우석대학교 한의과대학) ;
  • 안준 (미소로한의원 전주점) ;
  • 정혜인 (우석대학교 한의과대학 예방의학교실) ;
  • 김경한 (우석대학교 한의과대학 예방의학교실) ;
  • 장인수 (우석대학교 한의과대학 한방내과학교실) ;
  • 최유민 (우석대학교 한의과대학 침구의학교실) ;
  • 오용택 (우석대학교 한의과대학 진단학교실)
  • Received : 2021.10.08
  • Accepted : 2021.12.05
  • Published : 2022.02.28

Abstract

Objective : The purpose of this study is to present a case report with the adult patient who needed active treatment of pityriasis rosea with severe pruritus, and did not respond to steroid treatment in the preceding month. Methods : The subject is an adult patient with pityriasis rosea over the age of 40 without any other diseases. We administered Korean medicine treatment with Bangpungtongseong-san (防⾵通聖散) and acupuncture. The effects of the treatment were evaluated via scales including Pruritus score, Pityriasis Rosea Severity Score (PRSS), and picture. Results : After the treatment Pruritus score/PRSS index of the case changed from 8/20 to 0/0. No other severe adverse reactions were reported. No more recurrence or pruritus was confirmed in follow-up. Conclusions : Korean medicine treatment with Bangpungtongseong-san showed marked improvement in pruritus and skin symptoms of pityriasis rosea in need of active care. With the lack of existing clinical reports of pityriasis rosea, we found that Korean medicine treatment could be an effective way, and it is expected that Bangpungtongseong-san could be administered to pityriasis rosea patients. Randomized-controlled trial for further evaluation will be needed in the future.

장미색 비강진 환자에게 방풍통성산(防風通聖散)을 투여하여 증상의 호전과 치료의 안전성을 확인할 수 있었다. 소양감이 심하여 일상에 영향을 받는 등 치료가 필요한 상황이었고, 앞선 스테로이드 치료에는 반응하지 않았지만 한약 복용 후 소양감 및 피부 증상의 뚜렷한 개선을 보였다. 기존의 연구 보고를 근거로 방풍통성산(防風通聖散)이 소염 및 해열작용을 통해 피부 질환에서 유효한 효과를 갖는 것으로 보이고, 이로써 장미색 비강진에서 치료 효과를 발휘한 것으로 사료된다.

Keywords

Acknowledgement

본 연구는 2021년 우석대학교의 교내 연구비 지원을 받아 수행되었습니다.

References

  1. Leung AKC, Lam JM, Leong KF, Hon KL. Pityriasis Rosea: An Updated Review. Curr Pediatr Rev. 2020.
  2. Contreras-Ruiz J, Peternel S, Jimenez Gutierrez C, Culav-Koscak I, Reveiz L, Silbermann-Reynoso ML. Interventions for pityriasis rosea. Cochrane Database Syst Rev. 2019;30(10):CD005068.
  3. Alame MM, Chamsy DJ, Zaraket H. Pityriasis rosea-like eruption associated with ondansetron use in pregnancy. Br J Clin Pharmacol. 2018;84(5): 1077-1080. https://doi.org/10.1111/bcp.13560
  4. Chuh A, Zawar V, Sciallis G, Kempf W. A position statement on the management of patients with pityriasis rosea. J Eur Acad Dermatol Venereol. 2016;30(10):1670-1681. https://doi.org/10.1111/jdv.13826
  5. Kim HD, Won TH, Seo PS, Yoon NH, Park SD. Suspected Case of Iatrogenic Cushing Syndrome Due to Topical Steroid. Korean Journal of Dermatology. 2007;45(9):947-50.
  6. Jung MY, Kim MJ, Kim DS, Park YH, Kim JH, Park SY, et al. Pityriasis rosea: Report of 1 Case Treated by Oriental Medicine. J Korean Med Ophthalmol Otolaryngol Dermatol. 2007;20(3):268-75.
  7. Textbook Compilation Committee of National University of Traditional Korean Dermatology & Surgery. Textbook of Traditional Korean Dermatology & Surgery. Busan:Sunwo. 2007:586-8.
  8. Kwak JY, Lee YH, Shin SH, Ahn JH, Kim MH, Choi IH. Three cases of Pityriasis Rosea in Child treated with Eunkyo-san. J Korean Med Ophthalmol Otolaryngol Dermatol. 2017;30(2):155-164. https://doi.org/10.6114/JKOOD.2017.30.2.155
  9. Chuh AAT. Diagnostic criteria for pityriasis rosea - a prospective case control study for assessment of validity. J Eur Acad Dermatol Venereol. 2003;17: 101-103. https://doi.org/10.1046/j.1468-3083.2003.00519_4.x
  10. Drago F, Ciccarese G, Rebora A, Parodi A. Pityriasis rosea and pityriasis rosea-like eruption: can they be distinguished? J Dermatol. 2014;41(9): 864-5. https://doi.org/10.1111/1346-8138.12562
  11. Baek JO, Kim M, Roh JY, Lee JR, Lee AY. The Effect of Oral Famciclovir in Pityriasis Rosea. Korean Journal of Dermatology. 2007;45(12): 1240-1245.
  12. Shin KH. Pharmacological action of steroids. Educational course. 2002;2002(0):3-5.
  13. Shin SH, Yun JM, Heo JE, Ko WS, Yoon HJ. A Case Study on Steroid Rebound Phenomenon after Steroids Treatment for Pompholyx. J Korean Med Ophthalmol Otolaryngol Dermatol. 2014;27(3): 155-161. https://doi.org/10.6114/JKOOD.2014.27.3.155
  14. Lim KM, Song JH, Choi JH, Kim JH, Jung MY, Park SY. Effects of Three Types of GagamBangpungtongseong-san(Except Talcum) on the Atopic Dermatitis in Mice. 2020;33(3):1-26. https://doi.org/10.6114/JKOOD.2020.33.3.001
  15. Lee KH, Chang GT. Three Cases Report of Children Psoriasis treated by Bangpungtongsungsan. 2009;23(3):207-216.
  16. Park MJ, Yang JY, Kim SH, Cho KH, Moon SK, Kwon SW, et al. A Case Study of a Herpes Zoster Ophthalmicus Patient Treated by Korean-Western Cooperative Treatment. J Int Korean Med. 2018; 39(2):159-164. https://doi.org/10.22246/jikm.2018.39.2.159
  17. Talactac MR, Chowdhury MY, Park ME, Weeratunga P, Kim TH, Cho WK, et al. Antiviral Effects of Novel Herbal Medicine KIOM-C, on Diverse Viruses. PLoS One. 2015;10(5):e0125357. https://doi.org/10.1371/journal.pone.0125357
  18. Sabouri Ghannad M, Mohammadi A, Safiallahy S, Faradmal J, Azizi M, Ahmadvand Z. The Effect of Aqueous Extract of Glycyrrhiza glabra on Herpes Simplex Virus 1. Jundishapur J Microbiol. 2014;7(7):e11616. https://doi.org/10.5812/jjm.11616
  19. Kim HJ, Ji YS, Lee SM, Jeon JH, Kim YI. A Systematic Review of Clinical Study of Bee Venom Acupuncture. The Acupuncture. 2013;30(4):151-159.
  20. Sartim MA, Menaldo DL, Sampaio SV. Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties. J Venom Anim Toxins Incl Trop Dis. 2018;24:39. https://doi.org/10.1186/s40409-018-0178-3