Acknowledgement
본 결과물은 환경부의 재원으로 한국환경산업기술원의 야생생물 유래 친환경 신소재 및 공정기술개발사업(과제번호 : 2021003270008)의 지원을 받아 연구되었습니다.
References
- Szopa A, Ekiert R, Ekiert H. Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies. Phytochem Rev. 2017;16(2):195-218. https://doi.org/10.1007/s11101-016-9470-4
- Hu G, Qi Z, Wang A, Jia J. Effects of Deacidification on Composition of Schisandra chinensis Ethanolic Extract and Studies on Acute Toxicity in Mice. Molecules. 2020;25(24):6038. https://doi.org/10.3390/molecules25245814
- Kopustinskiene DM, Bernatoniene J. Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents. Antioxidants (Basel). 2021;10(4):620.
- Nowak A, Zaklos-Szyda M, Blasiak J, Nowak A, Zhang Z, Zhang B. Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives. Nutrients. 2019;11(2):333.
- Ekiert R.J., Szopa A., Ekiert H., Krzek J., Dzik E. Analysis of lignans in Schisandra chinensis fruits, leaves, biomasses from in vitro cultures and food supplements. J. Funct. Foods. 2013;5:1576-1581. https://doi.org/10.1016/j.jff.2013.06.008
- Mocan A., Crisan G., Vlase L., Crissan O., Vodnar D.C., Raita O., Gheldiu A.M., Toiu A., Oprean R., Tilea I. Comparative studies on polyphenolic composition, antioxidant and antimicrobial activities of Schisandra chinensis leaves and fruits. Molecules. 2014;19:15162-15179. https://doi.org/10.3390/molecules190915162
- Szopa A., Ekiert H. The importance of applied light quality on the production of lignans and phenolic acids in Schisandra chinensis (Turcz.) Baill. cultures in vitro. Plant Cell Tissue Organ Cult. 2016;127:115-121. https://doi.org/10.1007/s11240-016-1034-1
- Jiang Y, Fan X, Wang Y, et al. Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation. Chem Biol Interact. 2015;231:83-89. https://doi.org/10.1016/j.cbi.2015.02.022
- Hu D, Yang Z, Yao X, et al. Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells. Phytochemistry. 2014;104:72-78. https://doi.org/10.1016/j.phytochem.2014.04.014
- Jeong EJ, Lee HK, Lee KY, et al. The effects of lignan-riched extract of Shisandra chinensis on amyloid-β-induced cognitive impairment and neurotoxicity in the cortex and hippocampus of mouse. J Ethnopharmacol. 2013;146(1):347-354. https://doi.org/10.1016/j.jep.2013.01.003
- Park HJ, Cho JY, Kim MK, et al. Anti-obesity effect of Schisandra chinensis in 3T3-L1 cells and high fat diet-induced obese rats. Food Chem. 2012;134:227-234. https://doi.org/10.1016/j.foodchem.2012.02.101
- Kim J.W., Ku S.K., Han M.H., Kim K.Y., Kim S.G., Kim G.Y., Hwang H.J., Kim B.W., Kim C.M., Choi Y.H. The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice. Int. J. Mol. Med. 2015;36:29-42. https://doi.org/10.3892/ijmm.2015.2200
- Korea Food and Drug Administration. Notification No. 2009-116 Testing Guidelines for Safety Evaluation of Drugs. (2009) Aug 24;
- Organization for Economic Co-Operation and Development. Guideline for the Testing of Chemicals TG No. 474. Mammalian Erythrocyte Micronucleus Test. (1997) Jul 21;
- EFSA Scientific Committee (SC), More SJ, Bampidis V, et al. Guidance on aneugenicity assessment. EFSA J. 2021;19(8):e06770.
- Chung IK, Cheon WH, Ku SK. Micronucleus Test of Picrorrhiza Rhizoma Aqueous Extract in Bone Marrow Cells of Male ICR Mice. Toxicol Res. 2011;27(2):119-123. https://doi.org/10.5487/TR.2011.27.2.119
- Li Z, He X, Liu F, Wang J, Feng J. A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera: Properties, functions and applications. Carbohydr Polym. 2018;184:178-190. https://doi.org/10.1016/j.carbpol.2017.12.058
- Panossian A, Wikman G. Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine. J Ethnopharmacol. 2008;118(2):183-212. https://doi.org/10.1016/j.jep.2008.04.020
- Choo SH, Sung HH, Chae MR, et al. Effects of Schisandra chinensis extract on the relaxation of isolated human prostate tissue and smooth muscle cell. J Ethnopharmacol. 2014;156:271-276. https://doi.org/10.1016/j.jep.2014.08.025
- Lu Y, Chen DF. Analysis of Schisandra chinensis and Schisandra sphenanthera. J Chromatogr A. 2009;1216(11):1980-1990. https://doi.org/10.1016/j.chroma.2008.09.070
- Park WS, Koo KA, Bae JY, et al. Dibenzocyclooctadiene Lignans in Plant Parts and Fermented Beverages of Schisandra chinensis. Plants (Basel). 2021;10(2):361.
- Kim, H.-J., Seo, Y.-M., Lee, E.-J., Chung, C., Sung, H.-J., Sohn, H.-Y., … Kim, J.-S. (2018). Anti-proliferative and Pro-apoptotic Activities by Pomace of Schisandra chinensis (Turcz.) Baill. and Schizandrin. Journal of Life Science, 28(4), 415-420. https://doi.org/10.5352/JLS.2018.28.4.415
- Park, B. N., & Lee, J.-W. Antioxidation activity of residue after omija (Schisandra chinensis) juice extract. Journal of Applied Biological Chemistry. 2017; 60(2) 95-100. https://doi.org/10.3839/jabc.2017.016
- von Ledebur M, Schmid W. The micronucleus test. Methodological aspects. Mutat Res. 1973;19(1):109-117. https://doi.org/10.1016/0027-5107(73)90118-8
- Heddle J.A., Stuart E., Salamone M.F., Kilbey B.J, Legator M., Nichols W., Ramel C. The bone marrow micronucleus test in Handbook of mutagenicity test procedures. Elsevier; Amsterdam: (1984). pp. 441-457.
- Heddle JA, Hite M, Kirkhart B, et al. The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res. 1983;123(1):61-118. https://doi.org/10.1016/0165-1110(83)90047-7
- Heddle J.A. A rapid in vivo test for chromosome damage. Mutat. Res. (1973);18:187-190. https://doi.org/10.1016/0027-5107(73)90035-3
- Miyauchi A, Hiramine C, Tanaka S, Hojo K. Differential effects of a single dose of cyclophosphamide on T cell subsets of the thymus and spleen in mice: flow cytofluorometry analysis. Tohoku J Exp Med. 1990;162(2):147-167. https://doi.org/10.1620/tjem.162.147
- El-Bayoumy K. The protective role of selenium on genetic damage and on cancer. Mutat Res. 2001;475(1-2):123-139. https://doi.org/10.1016/S0027-5107(01)00075-6