Examination of Dose Change at the Junction at the Time of Treatment Using Multi-Isocenter Volumetric Modulated Arc Therapy

용적조절호형방사선치료(VMAT)의 다중치료중심(Multi- Isocenter)을 이용한 치료 시, 접합부(Junction)의 선량 변화에 대한 고찰

  • Jung, Dong Min (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Park, Kwang Soon (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Ahn, Hyuk Jin (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Choi, Yoon Won (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Park, Byul Nim (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Kwon, Yong Jae (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Moon, Sung Gong (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Lee, Jong Oon (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Jeong, Tae Sik (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Park, Ryeong Hwang (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Kim, Se young (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Kim, Mi Jung (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Baek, Jong Geol (Department of Radiation Oncology, Yonsei Cancer Center) ;
  • Cho, Jeong Hee (Department of Radiation Oncology, Yonsei Cancer Center)
  • 정동민 (연세암병원 방사선종양학과) ;
  • 박광순 (연세암병원 방사선종양학과) ;
  • 안혁진 (연세암병원 방사선종양학과) ;
  • 최윤원 (연세암병원 방사선종양학과) ;
  • 박별님 (연세암병원 방사선종양학과) ;
  • 권용재 (연세암병원 방사선종양학과) ;
  • 문성공 (연세암병원 방사선종양학과) ;
  • 이종운 (연세암병원 방사선종양학과) ;
  • 정태식 (연세암병원 방사선종양학과) ;
  • 박령황 (연세암병원 방사선종양학과) ;
  • 김세영 (연세암병원 방사선종양학과) ;
  • 김미정 (연세암병원 방사선종양학과) ;
  • 백종걸 (연세암병원 방사선종양학과) ;
  • 조정희 (연세암병원 방사선종양학과)
  • Published : 2021.12.31

Abstract

This study examined dose change depending on the reposition error of the junction at the time of treatment with multi-isocenter volumetric modulated arc therapy. This study selected a random treatment region in the Arccheck Phantom and established the treatment plan for multi-isocenter volumetric modulated arc therapy. Then, after setting the error of the junction at 0 ~ 4 mm in the X (left), Y (upper), and Z (inner and outer) directions, the area was irradiated using a linear accelerator; the point doses and gamma indexes obtained through the Phantom were subsequently analyzed. It was found that when errors of 2 and 4 mm took place in the X and Y directions, the gamma pass rates (point doses) were 99.3% (2.085) and 98% (2.079 Gy) in the former direction and 98.5% (2.088) and 95.5% (2.093 Gy) in the latter direction, respectively. In addition, when errors of 1, 2, and 4 mm occurred in the inner and outer parts of the Z direction, the gamma pass rates (point doses) were found to be 94.8% (2.131), 82.6% (2.164), and 72.8% (2.22 Gy) in the former part and 93.4% (2.069), 90.6% (2.047), and 79.7% (1.962 Gy) in the latter part, respectively. In the X and Y directions, errors up to 4 mm were tolerable; however, in the Z direction, error values exceeding 1 mm were beyond the tolerance level. This suggests that for high and low dose areas, errors in the direction same as the progress direction in the treatment region have a more sensitive dose distribution. If the guidelines for set-up errors are established at the institutional level through continuous research in the future, it will be possible to provide good quality treatment using junctions.

용적조절호형방사선치료(Volumetric Modulated Arc Therapy)의 다중치료중심(Multi-Isocenter)을 이용하여 치료 시, 접합부(Junction)의 재현 오차에 따른 선량변화에 대해 고찰하였다. Arccheck Phantom에 임의의 치료부위를 설정하고, 다중치료중심에 대해 치료계획을 수립하였다. 그리고 X(왼쪽), Y(위쪽), Z(안쪽, 바깥쪽) 방향에 대해서 접합부의 오차를 0 ~ 4 mm로 설정 후 선형가속기를 이용하여 방사선을 조사하였고, 이 후 phantom을 통해 얻어진 점 선량(point dose)과 감마인덱스(gamma Index)를 통해 분석하였다. X방향과 Y방향에 대한 오차가 2, 4 mm 발생 했을 때, 감마패스율(점 선량)은 각각 99.3% (2.085), 98% (2.079 Gy) 와 98.5% (2.088), 95.5% (2.093 Gy)로 나타났다. 그리고 Z방향에 대해서 안쪽과 바깥쪽에 대한 오차가 1, 2, 4 mm 발생 했을 때, 감마패스율(점 선량)은 각각 94.8% (2.131), 82.6% (2.164), 72.8% (2.22 Gy) 와 93.4% (2.069), 90.6% (2.047), 79.7% (1.962 Gy) 로 보여졌다. X, Y방향에 대해서 4 mm 까지의 오차 결과는 허용오차 안에 있었으나, Z방향에 대해서는 1 mm 를 초과하는 오차 값에 대해서 허용오차 밖의 결과 값이 도출되었다. 이는 높은 선량 영역(high dose area)과 낮은 선량 영역(low dose area)에 대해 치료부위의 진행방향과 같은 방향의 오차가 선량 분포(dose distribution)가 더 민감하다는 것을 시사한다. 향후 지속적인 연구를 통해 기관차원의 셋 업(set up) 오차에 대한 가이드라인이 정립된다면, 접합부를 이용한 치료에서 양질의 치료를 제공할 수 있을 것이라 사료된다.

Keywords

References

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