Fig. 1. Nitric oxide (NO) radical scavenging activity of various solvent extracts from turmeric (Curcuma longa L.).
Fig. 2. Nitrite (NO2) scavenging activity of various solvent extracts from turmeric (Curcuma longa L.).
Fig. 3. Antioxidant activity by β-carotene (BC) bleaching assay of various solvent extracts from turmeric (Curcuma longa L.).
Fig. 4. Lipid peroxidation inhibition (LPI) action of various solvent extracts from turmeric (Curcuma longa L.).
Table 1. Contents of total carotenoid and total phenol in the bioactivity evaluation assays from turmeric (Curcuma longa L.)
Table 2. IC50 values of NO radical scavenging activity, NO2 scavenging activity, antioxidant activity by BC bleaching assay and LPI action by turmeric (Curcuma longa L.)
References
- C. A. C. Araujo, L. L. Leon, "Biological activities of Curcuma longa L.", Mem. Inst. Oswaldo Cruz, Vol. 96, No. 5, pp. 723-728, (2001). https://doi.org/10.1590/S0074-02762001000500026
- R. Mohebbati, A. Anaeigoudari, M. R. Khazdair, "The effects of Curcuma longa and curcumin on reproductive systems", Endocrine Regulations, Vol. 51, No. 4, pp. 220-228, (2017). https://doi.org/10.1515/enr-2017-0024
- M. S. Kim, S. S. Chun, J. H. Choi, "Effects of turmeric (Curcuma longa L.) on antioxidative systems and oxidative damage in rats fed a high fat and cholesterol diet", J. Korean Soc. Food Sci. Nutr., Vol. 42, No. 4, pp. 570-576, (2013). https://doi.org/10.3746/jkfn.2013.42.4.570
- I. Ali, A. Haque, K. Saleem, "Separation and identification of curcuminoids in turmeric powder by HPLC using phenyl column", Anal. Methods, Vol. 6, No. 8, pp. 2526-2536, (2014). https://doi.org/10.1039/C3AY41987H
- I. Wientarsih, S. Chakeredza, U. ter Meulen, "Influence of curcuma (Curcuma xanthorrhiza Roxb) on lipid metabolism in rabbits", J. Sci. Food Agric., Vol. 82, No. 15, pp. 1875-1880, (2002). https://doi.org/10.1002/jsfa.1235
- E. Herrera, R. Jimenez, O. I. Aruoma, S. Hercberg, I. Sanchez-Garcia, C. Fraga, "Aspects of antioxidant foods and supplements in health and disease", Nutr. Rev., Vol. 67, No. s1, pp. S140-144, (2009). https://doi.org/10.1111/j.1753-4887.2009.00177.x
- H. Y. Huang, K. J. Helzlsouer, L. J. Appel, "The effects of vitamin C and vitamin E on oxidative DNA damage: results from a randomized controlled trial", Cancer Epidemiol. Biomarkers Prev., Vol. 9, No. 7, pp. 647-652, (2000).
- A. Valavanidis, T. Vlachogianni, C. Fiotakis, "8-hydroxy-2′-deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis", J. Environ. Sci. Health. Environ. Carcinog. Ecotoxicol. Rev., Vol. 27, No. 2, pp. 120-139, (2009). https://doi.org/10.1080/10590500902885684
- O. Arrigoni, M. C. De Tullio, "Ascorbic acid: much more than just an antioxidant", Biochimica Biophysica Acta, Vol. 1569, No. 1, pp. 1-9, (2002). https://doi.org/10.1016/S0304-4165(01)00235-5
- A. Seifi-Jamadi, H. Kohram, A. Zareh-Shahne, P. Dehghanizadeh, E. Ahmad, "Effect of various concentrations of butylated hydroxyanisole and butylated hydroxytoluene on freezing capacity of Turkman stallion sperm", Anim. Reprod. Sci., Vol. 170, pp. 108-113, (2016). https://doi.org/10.1016/j.anireprosci.2016.04.010
- L. Shen, H. Y. Zhang, H. F. Ji, "A thermodynamic investigation of DPPH radical-scavenging mechanisms of folates", J. Mol. Struct. (THEOCHEM), Vol. 856, No. 1-3, pp. 119-123, (2008). https://doi.org/10.1016/j.theochem.2008.01.023
- M. Valko, D. Leibfritz, J. Moncol, M. T. Cronin, M. Mazur, J. Telser, "Free radicals and antioxidants in normal physiological functions and human disease", Int. J. Biochem. Cell Biology., Vol. 39, pp. 44-84, (2007). https://doi.org/10.1016/j.biocel.2006.07.001
- R. L. Yang, Y. H. Shi, G. Hao, W. Li, G. W. Le, "Increasing oxidative stress with progressive hyperlipidemia in human: relation between malondialdehyde and atherogenic index", J. Clin. Biochem. Nutr., Vol. 43, No. 3, pp. 154-158, (2008). https://doi.org/10.3164/jcbn.2008044
-
H. Poudyal, S. Panchal, L. Brown, "Comparison of purple carrot juice and
${\beta}$ -carotene in a high-carbohydrate, high-fat diet-fed rat model of the metabolic syndrome", Br. J. Nutr., Vol. 104, No. 9, pp. 1322-1332, (2010). https://doi.org/10.1017/S0007114510002308 -
H. S. Black, "Interaction of ascorbic acid and tocopherolon
${\beta}$ -carotene modulated carcinogenesis", Hemoglobin, Vol. 34, No. 3, pp. 284-290, (2010). https://doi.org/10.3109/03630269.2010.485873 -
F. Q. Schafer, H. P. Wang, E. E. Kelley, K. L. Cueno, S. M. Martin, G. R. Buettner, "Comparing
${\beta}$ -carotene, vitamin E and nitric oxide as membrane antioxidants", Biol. Chem., Vol. 383, No. 3-4, pp. 671-681, (2002). https://doi.org/10.1515/BC.2002.069 - S. Machmudah, M. Goto, "Methods for extraction and analysis of carotenoids", Natural products, Springer Berlin Heidelberg, pp. 3367-3411, (2013).
- P. C. Wootton-Beard, A. Moran, L. Ryan, "Stability of the total antioxidant capacity and total polyphenol content of 23 commercially available vegetable juices before and after in vitro digestion measured by FRAP, DPPH, ABTS and Folin-Ciocalteu methods", Food Res. Intern., Vol. 44, No. 1, pp. 217-224, (2011). https://doi.org/10.1016/j.foodres.2010.10.033
- M. N. A. Rao, "Nitric oxide scavenging by curcuminoids", J. Pharm. Pharmacol., Vol. 49, No. 1, pp. 105-107, (1997). https://doi.org/10.1111/j.2042-7158.1997.tb06761.x
- A. Kumaran, R. J. Karunakaran, "Nitric oxide radical scavenging active components from Phyllanthus emblica L", Plant Foods Hum. Nutr., Vol. 61, No. 1, pp. 1-5, (2006). https://doi.org/10.1007/s11130-006-0001-0
-
A. L. Dawidowicz, M. Olszowy, "Influence of some experimental variables and matrix components in the determination of antioxidant properties by
${\beta}$ -carotene bleaching assay: experiments with BHT used as standard antioxidant", Eur. Food Res. Technol., Vol. 231, No. 6, pp. 835-840, (2010). https://doi.org/10.1007/s00217-010-1333-4 - N. Siriwardhana, K. W. Lee, Y. J. Jeon, S. H. Kim, J. W. Haw, "Antioxidant activity of Hizikia fusiformis on reactive oxygen species scavenging and lipid peroxidation inhibition", Food Sci. Technol. Int., Vol. 9, No. 5, pp. 339-346, (2003). https://doi.org/10.1177/1082013203039014
- F. Ahmed, K. Fanning, M. Netzel, P. M. Schenk, "Induced carotenoid accumulation in Dunaliella salina and Tetraselmis suecica by plant hormones and UV-C radiation", Appl. Microbiol. Biotechnol., Vol. 99, No. 22, pp. 9407-9416, (2015). https://doi.org/10.1007/s00253-015-6792-x
- S. Mongkolsilp, I. Pongbupakit, N. Sae-Lee, W. Sitthithaworn, "Radical scavenging activity and total phenolic content of medicinal plants used in primary health care", SWU. J. Pharm. Sci., Vol. 9, No. 1, pp. 32-35, (2004).
- A. Wojdylo, J. Oszmianski, R. Czemerys, "Antioxidant activity and phenolic compounds in 32 selected herbs", Food Chem., Vol. 105, No. 3, pp. 940-949, (2007). https://doi.org/10.1016/j.foodchem.2007.04.038
- H. Rubbo, C. Batthyany, R. Radi, "Nitric oxide: oxygen radical interactions in atherosclerosis", Biol. Res., Vol. 33, No. 2, pp. 167-175, (2000).
- G. M. Rosen, P. Tsai, S. Pou, "Mechanism of free-radical generation by nitric oxide synthase", Chem. Rev., Vol. 102, No. 4, pp. 1191-1200, (2002). https://doi.org/10.1021/cr010187s
- Y. Sueishi, M. Hori, M. Kita, Y. Kotake, "Nitric oxide (NO) scavenging capacity of natural antioxidants", Food Chem., Vol. 129, No. 3, pp. 866-870, (2011). https://doi.org/10.1016/j.foodchem.2011.05.036
- M. W. Byun, H. S. Yook, K. S. Kim, C. K. Chung, "Effects of gamma- irradiation on physiological effectiveness of Korean medicinal herbs", Radiat. Physic. Chem., Vol. 54, No. 3, pp. 291-300, (1999). https://doi.org/10.1016/S0969-806X(98)00233-3
-
A. L. Dawidowicz, M. Olszowy, "Influence of some experimental variables and matrix components in the determination of antioxidant properties by
${\beta}$ -carotene bleaching assay: experiments with BHT used as standard antioxidant", Eur. Food Res. Technol., Vol. 231, No. 6, pp. 835-840, (2010). https://doi.org/10.1007/s00217-010-1333-4 - P. Podloucka, K. Berka, G. Fabre, M. Paloncyova, J. L. Duroux, M. Otyepka, P. Trouillas, "Lipid bilayer membrane affinity rationalizes inhibition of lipid peroxidation by a natural lignan antioxidant", J. Physic. Chem. B, Vol. 117, No. 17, pp. 5043-5049, (2013). https://doi.org/10.1021/jp3127829
- E. J. Cho, T. Yokozawa, D. Y. Rhyu, H. Y. Kim, N. Shibahara, J. C. Park, "The inhibitory effects of 12 medicinal plants and their component compounds on lipid peroxidation", Am. J. Chinese med., Vol. 31, No. 6, pp. 907-917, (2003). https://doi.org/10.1142/S0192415X03001648