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S-PRG filler를 함유한 치면열구전색제의 미세누출 및 항우식효과

Microleakage and Anticariogenic Effect of S-PRG Filler-containing Pit and Fissure Sealant

  • 신승우 (단국대학교 치과대학 소아치과학교실) ;
  • 김종수 (단국대학교 치과대학 소아치과학교실)
  • Shin, Seungwoo (Department of Pediatric Dentistry, School of Dentistry, Dankook University) ;
  • Kim, Jongsoo (Department of Pediatric Dentistry, School of Dentistry, Dankook University)
  • 투고 : 2013.07.03
  • 심사 : 2013.09.07
  • 발행 : 2013.11.29

초록

치면열구전색은 생물막의 축적을 물리적으로 막아주며 박테리아에 의해 형성되는 산물질에 화학적 장벽 역할을 한다. 1999년 S-PRG(Surface reaction-type pre-reacted glass ionomer) 필러기술이 개발되었는데 S-PRG 필러는 수분 존재 하에서 스스로 분해되지 않으면서, 지속적으로 불소유리가 가능하다. 이에 저자는S-PRG 필러를 포함하는 치면열구전색제의 미세누출 및 인접 법랑질에 대한 항우식 효과를 기존의 유동성레진 치면열구전색제와 비교해 보고자 한다. 건전한 소구치, 대구치를 실험대상으로 사용하였다. S-PRG 필러를 함유해 불소를 유리하는 치면열구전색제 Beautisealant$^{(R)}$(Shofu, Japan)를 실험군으로, 유동성레진 치면열구전색제 Concise$^{(R)}$(3M ESPE, USA)를 대조군으로 선정하였다. 미세누출실험을 위해 실란트 변연 1 mm를 제외한 나머지 치아에 손톱광택제를 2회 도포 후 2% 메틸렌블루 용액에 24시간 동안 보관 후 수세하였다. 항우식효과의 평가는 인공우식용액에 9일간 보관 후 수세 후 시행하였다. 수세한 시편들은 투명레진에 매립 후 현미경 관찰을 위해 절단하였다. 통계분석은 미세노출의 정도는 Chisquare test를, 측정된 우식의 깊이는 Mann-Whitney test를 이용해 두 군 간의 유의성을 검증하였다. S-PRG 치면열구전색제와 유동성레진 치면열구전색제의 미세누출 차이는 관찰되지 않았지만, S-PRG 치면열구전색제는 유동성레진 치면열구전색제 보다 더 높은 항우식효과를 보이는 것으로 나타났다.

Pit and fissure sealant prevents biofilm accumulation, plays a role in forming a barrier to acidic substance made by the bacteria. The Surface reaction-type pre-reacted glass ionomerI(S-PRG) filler was developed in 1999. S-PRG filler releases fluoride continuously and does not decompose under wet conditions. The aim of this study was to test the microleakage and anticariogenic effect to adjacent enamel of S-PRG filler-containing pit and fissure sealant. Sound premolars and molars were used in this study. A S-PRG filler-containing pit and fissure sealant, Beautisealant$^{(R)}$(Shofu, Japan) was used for this experiment, the composite resin sealant Concise$^{(R)}$(3M ESPE, USA) was used as control. For the microleakage test, all teeth surface were double coated with finger nail varnish, with the exception of a 1.0 mm window around the restoration margins. The teeth were immersed in 2% methylene blue solution for 24 hours and then rinsed in tap water. For the anticariogenic effect evaluation, all tooth were immersed in artificial carious solution for 9 days and rinsed with tap water. Each tooth was embedded in orthodontic acrylic rein and subsequently sectioned longitudinally in a bucco-lingual direction with a low-speed diamond saw. The cut sections were examined using a stereomicroscope. Differences in microleakage between the two groups were not different significantly. But the S-PRG filler-containing pit and fissure sealant showed higher anticariogenic effect than that of flowable resin sealant.

키워드

참고문헌

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피인용 문헌

  1. Antibacterial Properties of Pit and Fissure Sealant Containing S-PRG filler on <i>Streptococcus mutans</i> vol.42, pp.4, 2015, https://doi.org/10.5933/JKAPD.2015.42.4.302
  2. Shear Bond Strength and Microleakage of a New Self-etch Sealant Containing S-PRG filler vol.43, pp.4, 2016, https://doi.org/10.5933/JKAPD.2016.43.4.347