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The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Examination of Bioconcentration of a New Algicide, Thiazolidinedione Derivative (TD49) to Marine Organisms

신규 살조제 Thiazolidinedione 유도체 (TD49)의 해양생물에 대한 생물 농축도 조사

  • Shin, Jun-Jae (Interdisciplinary Program of Bioenergy and Biomaterials, Chonnam National University) ;
  • Kim, Si-Wouk (Department of Environmental Engineering, Chosun University) ;
  • Cho, Hoon (Department of Polymer Science & Chemical Engineering, Chosun University) ;
  • Kim, Seong-Jun (Department of Environmental Engineering, Chonnam National University)
  • 신준재 (전남대학교 바이오에너지 및 바이오소재협동과정) ;
  • 김시욱 (조선대학교 환경공학과) ;
  • 조훈 (조선대학교 응용화학소재공학과) ;
  • 김성준 (전남대학교 환경공학과)
  • Received : 2012.02.21
  • Accepted : 2012.03.13
  • Published : 2012.04.30
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Abstract

In this study, a newly synthesized thiazolidinedione derivative, TD49 with a highly selective algicide to red tide, was examined in order to evaluate the bioconcentration on aquatic organisms of coast. BAF (accumulation of TD49 by aquatic food chain) and BCF (accumulation of TD49 by sea water) were examined employing the shrimp (Fenneropenaeus chinensis) as the feed organism, and the olive flounder Paralichthys olivaceus as a consumer in marine ecosystem. Bioconcentration degree in sea water showed that the order in P. olivaceus was viscera > gill > muscle. The average BCF values of TD49 were 67.70, 63.32 and 20.25 at viscera, gill and muscle, respectively. Bioaccumulation degree using feed showed that the order in the organs of P. olivaceus was viscera > gill > muscle. The average BAF values of TD49 were 175.89, 114.88 and 32.59 at viscera, gill and muscle, respectively. When compared with two results, the accumulation by the food and water was higher than that by water. After the elimination experiment in sea water, the TD49 concentration was 2.81 nmole/g in the viscera and were not found in the gill and the muscle. More than 50% of the accumulated TD49 were eliminated from viscera in 7 days and all the accumulated TD49 were eliminated from gill and muscle in 7 days. On the other hand, the octanol/water partition coefficient (log $K_{ow}$) was measured to be 3.66 and experimental BCF of this study was 67.7.

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References

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