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http://dx.doi.org/10.7841/ksbbj.2012.27.2.091

Examination of Bioconcentration of a New Algicide, Thiazolidinedione Derivative (TD49) to Marine Organisms  

Shin, Jun-Jae (Interdisciplinary Program of Bioenergy and Biomaterials, Chonnam National University)
Kim, Si-Wouk (Department of Environmental Engineering, Chosun University)
Cho, Hoon (Department of Polymer Science & Chemical Engineering, Chosun University)
Kim, Seong-Jun (Department of Environmental Engineering, Chonnam National University)
Publication Information
KSBB Journal / v.27, no.2, 2012 , pp. 91-96 More about this Journal
Abstract
In this study, a newly synthesized thiazolidinedione derivative, TD49 with a highly selective algicide to red tide, was examined in order to evaluate the bioconcentration on aquatic organisms of coast. BAF (accumulation of TD49 by aquatic food chain) and BCF (accumulation of TD49 by sea water) were examined employing the shrimp (Fenneropenaeus chinensis) as the feed organism, and the olive flounder Paralichthys olivaceus as a consumer in marine ecosystem. Bioconcentration degree in sea water showed that the order in P. olivaceus was viscera > gill > muscle. The average BCF values of TD49 were 67.70, 63.32 and 20.25 at viscera, gill and muscle, respectively. Bioaccumulation degree using feed showed that the order in the organs of P. olivaceus was viscera > gill > muscle. The average BAF values of TD49 were 175.89, 114.88 and 32.59 at viscera, gill and muscle, respectively. When compared with two results, the accumulation by the food and water was higher than that by water. After the elimination experiment in sea water, the TD49 concentration was 2.81 nmole/g in the viscera and were not found in the gill and the muscle. More than 50% of the accumulated TD49 were eliminated from viscera in 7 days and all the accumulated TD49 were eliminated from gill and muscle in 7 days. On the other hand, the octanol/water partition coefficient (log $K_{ow}$) was measured to be 3.66 and experimental BCF of this study was 67.7.
Keywords
Bioconcentration; BCF; BAF; Algicide; Fenneropenaeus chinensis; Paralichthys olivaceus;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
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1 Kim, N. S., S. H. Hong, W. J. Shim, and J. K. Jeon (2007) Accumulation of tributyltin (TBT) in blood, liver and muscle of olive flounder. J. Environ. Toxicol. 22: 19-26.   과학기술학회마을
2 Cho, Y. G. and G. B. Kim (2007) Bioaccumulation of Pb and Cd in blue mussel (Mytilus edulis) and oliver flounder (Paralichthys olivaceus) exposed to rearing media. J. Korean Soc. Mar. Environ. Eng. 10: 21-28.   과학기술학회마을
3 Neely, W. B., D. R. Branson, and G. E. Blau (1974) Partition coefficient to measure bioconcentration potential of organic chemicals in fish. Environ. Sci. Technol. 8: 1113-1115.   DOI   ScienceOn
4 Veith, G. D., D. L. Defoe, and B. V. Bergstedt (1979) Measuring and estimating the bioconcentration factor of chemicals on fish. J. Fish. Res. Board Can. 36: 1040-1048.   DOI
5 Mackay, D. (1982) Correlation of bioconcentration factors. Environ. Sci. Technol. 16: 274-278.   DOI
6 Chlou, C. T. (1985) Partition coefficients of organic compounds in lipid-water systems and correlations with fish bioconcentration factors. Environ. Sei. Technol. 19: 57-62.   DOI
7 Kwon, J. H. (2008) Bioaccumulation and baseline toxicity of hydrophobic chemicals: molecular size cutoff, kinetic limitations, and chemical activity cut-off. J. Environ. Toxicol. 23: 67-77.   과학기술학회마을
8 Leeuwen, C. J. V. and J. L. M. Hermens (2001) Risk Assessment of Chemicals: An introduction. 1st ed., pp. 367-373. Kluwer Academic Publishers, Boston, USA.
9 Lee, H. G., H. Cho, and H. K. Han (2010) Improved dissolution of poorly water soluble TD49, a novel algicidal agent, via the preparation of solid dispersion. J. Pharm. Invest. 40: 181-185.   과학기술학회마을   DOI
10 Kim, M. Y., W. Ying, T. U. Duong, G. S. Ghodake, S. W. Kim, E. S. Jin, and H, Cho (2010) Thiazolidinediones as a novel class of algicides against red tide harmful algal species. Appl. Biochem. Biotechnol. 162: 2273-2283.   DOI
11 Kim, S. J., E. C. Yim, I. T. Park, S. W. Kim, and H. Cho (2011) Comparison of the acute tocixities of novel algicides, thiazolidinedione derivatives TD49 and TD53, to various marine organisms. Environ. Toxicol. Chem. 30: 2810-2816.   DOI
12 Duong, T. U. (2010) Synthesis and SAR of Thiazolidinedione as a Novel Class of Algicides Against Harmful Algal Species. MS Thesis. Chosun University Graduate School, Gwangju, Korea.
13 OECD guideline for testing of chemicals (1996) Bioconcentration, Flow-Through Fish Test (No. 305).
14 Munger, C. and L. Hare (1997) Relative importance of water and food as cadmium sources to an aquatic insect (Chaoborus punctipennis): implications for predicting Cd bioaccumulation in nature. Environ. Sci. Technol. 31: 891-895.   DOI   ScienceOn
15 OECD guideline for testing of chemicals (2006) Partition Coefficient (1-Octanol/Water): Slow-Stirring Method (No.123).
16 Fisk, A. T., B. Rosenberg, C. D. Cymbalisty, G. A. Stern, and D. C. G. Muir. (1999) Octanol/water partition coefficients of toxaphene congeners determined by the "slow-stirring" method. Chemosphere 39:2549-2562.   DOI   ScienceOn
17 Palaniappan, P. L. R. M., T. Nishanth, and V. B. Renju (2010) Bioconcentration of zinc and its effect on the biochemical constituents of the gill tissues of Labeo rohita: An FT-IR study. Infrared Phys. Technol. 53: 103-111.   DOI
18 Choi, H. G., P. J. Kim, W. C. Lee, S. J. Yun, H. G. Kim, and H. J. Lee (1998) Removal efficiency of Cochlodinium polykrikoids by yellow loess. J. Korean Fish. Soc. 31: 109-113.   과학기술학회마을
19 Jeong, J. H., H. J. Jin, C. H. Shon, K. H. Suh, and Y. K. Hong (2000) Algicidal activity of the seaweed Corallina pilulifera against red tide microalgae. J. Appl. Phycol. 12: 37-43.   DOI   ScienceOn
20 Park, J. J., J. C. Park, S. S. Kim, H. S. Cho, Y. G. Lee, and J. S. Lee (2009) Histological response of digestive gland of Gomphina veneriformis with TBTCl accumulation in sediment and soft tissue. J. Environ. Toxicol. 24: 341-350.   과학기술학회마을
21 Sun, X. X., J. K. Choi, and E. K. Kim (2004) A preliminary study on the mechanism of hamful algal bloom mitigation by use of sophorolipid treatment. J. Exp. Mar. Biol. Ecol. 304: 35-49.   DOI   ScienceOn
22 Steidinger, K. A. (1983) A re-evaluation of toxic dinoflagellate biology and ecology. Prog. Phycol. Res. 2: 147-188.
23 Garry, R. T., P. Hearing, and E. M. Cosper (1998) Characterization of a lytic virus infectious to the bloom-forming microalga Aureococcus anophagefferens (Plagophyceae). J. Phycol. 34: 616-621.   DOI   ScienceOn
24 Park, Y. T., J. B. Park, S. Y. Chung, B. C. Song, W. A. Lim, C. H. Kim, and W. J. Lee (1998) Isolation of marine bacteria killing red tide microalgae I. Isolation and algidal propertoes of Micrococcus sp. LG-1 possessing killing activity for harmful dinoflagellate, Cochlodinium Polykrikoides. J. Korean Fish. Soc. 31: 767-773.   과학기술학회마을
25 Lee, W. J. and Y. T. Park (1998) Isolation of marine bacteria killing red tide microalgae II. Isolation and algicidal properties of Pseudomonas sp. LG-2 possessing killing activity for dinoflagellate, Prorocentrum micans. J. Korean Fish. Soc. 31: 852-858.   과학기술학회마을