알코올 섭취 후 시간경과에 따른 시 기능의 변화

Time-dependent Changes of Ocular Functions after Alcohol Ingestion

  • 김상엽 (경운대학교 안경광학과) ;
  • 문병연 (경운대학교 안경광학과) ;
  • 이선행 (계명대학교 공중보건학과) ;
  • 조현국 (경운대학교 안경광학과)
  • 투고 : 2009.01.28
  • 심사 : 2009.03.06
  • 발행 : 2009.03.31

초록

목적: 혈 중 알코올 농도의 증가가 시력 및 시 기능에 미치는 영향을 알아보고자 하였다. 방법: 체중 kg당 0.7g의 알코올을 섭취하고 1시간, 4시간 및 24시간이 경과한 후의 혈 중 알코올 농도, 시력, 굴절이상도, 폭주근점, 상대조절력, 사위, 그리고 상대폭주력의 변화를 측정하고 분석하였다. 결과: 알코올 섭취 1시간 경과 후, 혈 중 알코올 농도는 가장 높았고 근시화 및 측정 폭주근점, 양성 음성상대폭주력과 사위도의 변화가 가장 크게 나타났다. 그러나 알코올 섭취 24시간 경과 후에는 대부분의 검사값들이 알코올 섭취 전의 90%~99% 수준까지 복귀되는 것으로 나타났다. 결론: 혈 중 알코올 농도의 증가는 시력 및 시 기능 진단에 의의있는 변화를 일으킬 수 있으므로, 굴절검사 및 시 기능검사 전 알코올 섭취에 대한 사전 정보를 충분히 파악하여야 할 것이다.

Purpose: This study was designed to investigate the changes of vision and ocular functions induced by increase of blood alcohol level. Methods: Blood alcohol level, vision, refractive errors, near point convergence, heterophoria, and relative convergence were measured at 1 h, 4 h, and 24 h after acute alcohol ingestion of 0.7 g per kg body weight. Results: At 1 h after alcohol ingestion, myopization and ocular functions which measured near point convergence, positive and negative convergences, and degree of heterophoria remarkedly worked a changes accompanied with the maximum value of blood alcohol level. But at 24 h after that, all of ocular functions were recovered to degree of 90~99% compared with non-alcoholic normal conditions. Conclusions: As the increase of blood alcohol level is able to induce the significant changes of visual acuity and ocular functions, opticians have to understand thoroughly the patient's conditions by alcohol ingestion before refractive test and ocular examinations.

키워드

참고문헌

  1. Yang J. M., "Metabolism of alcohol and its clinical role", Korean J. Hepatol., 7(3):345-348(2001).
  2. Yang J. M., "Extrahepatic manifestations of alcoholic injury", Korean J. Hepatol., 7(4):491-493(2001).
  3. Kim J. M., "The effects of drugs including alcohol on ocular health and contact lens wear", J. Korean Oph. Opt. Soc., 5(1):73-81(2000).
  4. Clayton R. M., Cuthbert J., Duffy J., Seth J., Phillips C. I., Bartholomew R. S., and Reid J. M., "Some risk factors associated with cataract in SE Scotland: A pilot study", Trans. Oph. Soc. UK., 102:331-336(1982).
  5. Powell W. H. Jr., "Ocular manifestations of alcohol and considerations of individual variations in 7 cases investigated", J. Aviat. Med., 9:97-103(1938).
  6. Hogan R. E. and Linfield P. B., "The effects of moderate doses of ethanol on heterophoria and other aspects of binocular vision", Ophthal. Physiol. Opt., 3(1):21-31(1983). https://doi.org/10.1111/j.1475-1313.1983.tb00576.x
  7. Brecher G. A., Hartman A. P., and Leonard D. D., "Effect of alcohol on binocular vision", Am. J. Ophthal., 39: 44-52(1955). https://doi.org/10.1016/0002-9394(55)90008-8
  8. Hill J. C. and Toffolon G., "Effect of alcohol on sensory and sensorimotor visual function", J. Stud. Alcohol, 51: 108-113(1990). https://doi.org/10.15288/jsa.1990.51.108
  9. Wilkinson I. M. S., Kime R., and Purnell M., "Alcohol and human eye movement", Brain, 97(4):785-792(1974). https://doi.org/10.1093/brain/97.1.785
  10. Watten R. G. and Lie I., "Visual functions and acute ingestion of alcohol", Ophthal. Physiol. Opt., 16(6):460-466 (1996). https://doi.org/10.1016/0275-5408(96)00020-8
  11. Mergler D., Blain L., Lemaire J., and Lalande F., "Colour vision impairment and alcohol consumption", Neurotoxicol. Teratol., 10:255-260(1988). https://doi.org/10.1016/0892-0362(88)90025-6
  12. Kim S. Y., Lee S. H., Moon B. Y., Yu D. S., and Cho H. G., "Time-dependent changes of visual acuity after alcohol ingestion", J. Korean Oph. Opt. Soc., 13(2):59-62 (2008).
  13. Fillmore M. T. and Weafer J., "Alcohol impairment of behavior men and women", Addiction, 99:1237-1246(2004). https://doi.org/10.1111/j.1360-0443.2004.00805.x
  14. Mitchell S. and Bruce W., "Clinical Management of Binocular Vision", 2nd Ed., Lippincott Williams & Wilkins, USA, pp. 58(2002).
  15. Newman H. and Fletcher E., "The effect of alcohol on vision", Am. J. Med. Sci., 202:723-730(1941). https://doi.org/10.1097/00000441-194111000-00014
  16. Wilson G. and Mitchell R., "The effect of alcohol on the visual and ocular motor system", Australian J. Ophthal., 11:315-319(1983). https://doi.org/10.1111/j.1442-9071.1983.tb01099.x
  17. Olsen E. G. and Olsen H., "Influence of ethanol ingestion on the cornea", Acta. Ophthal.(Copenh), 71(5):696-698 (1993).
  18. Moskowitz H., Sharma S., and Schapero M., "A comparison of the effects of marijuana and alcohol on visual function", In M. F. Lewis(Eds), Current Researchs in Marijuana, Academic Press, N.Y., pp. 129-150(1972).
  19. Wallgren H. and Barry H., "Actions of Alcohol. Vol. 1. Biochemical, Physiological and Psychological Aspects", Elsvier, N.Y., pp. 310(1970).
  20. Faber D. S. and Klee M. R., "Action of Ethanol on Neuronal Membrane Properties and Synaptic Transmission in Alcohol and Opiates", Academic press, London (1977).
  21. Colson Z. W., "The effect of alcohol on vision", J. Am. Med. Assoc., 115:1525-1527(1940). https://doi.org/10.1001/jama.1940.02810440017004
  22. 김덕훈, 김상문, 김재민, 김창식, 성아영, 정수자, 조현수, "시기 생리학", 개정 3판, 현문사, 서울, pp. 149-156 (2005).