The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Effects of Bangpoongtongsungsankamibang extract on the obese SD rats induced by 2% cholesterol diet

방풍통성산가미방(防風通聖散加味方)이 비만유도(肥滿誘導) 백서(白鼠)에 미치는 영향(影響)

  • Kim, Deog-Gon (Department of Pediatrics, college of Oriental Medicine, Kyunghee University) ;
  • Kim, Byung-Woo (Department of Pediatrics, college of Oriental Medicine, Kyunghee University)
  • 김덕곤 (경희대학교 한의과대학 소아과학교실) ;
  • 김병우 (경희대학교 한의과대학 소아과학교실)
  • Published : 2007.04.30
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Abstract

Objectives : These experimental studies were designed to investigate the effects of Bangpoongtongsungsankamibang on the weight and the lipid metabolism of the obese rats induced by 2% cholesterol diet. They were designed to change values in the serum and leptin levels in the rats. Materials and Methods : The serum and leptin levels were measured for a period of 8 weeks for obese SD rats induced by 2% cholesterol diet. Results : The body weight showed a tendency to decreased significantly in sample (p<0.05). The Total cholesterol and Triglyceride level significantly decreased in sample (p<0.05). The HDL Cholesterol levels significantly increased in sample (p<0.05). The LDH levels did not show a significant change in sample. The ALP levels significantly decreased in sample (p<0.05). The SGOT and SGPT level did not show a significant change in sample. The Leptin levels significantly decreased in sample (p<0.05). The average size of the epididymal fat cell significantly decreased in sample (p<0.05).

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