Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
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Fabrication and Performance Evaluation of a Micro Separation Chip of Magnetic Beads Using Magnetophoretic Flow

자기영동을 이용한 자성입자 분리 마이크로 칩 제작 및 성능평가

  • 고정상 (부산대학교 기계공학부, 부산대학교 기계기술연구소(RIMT))
  • Published : 2007.04.01
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Abstract

We developed a microfluidic platform able to control the trap and release of magnetic beads used for separation of a specific biomolecules. The magnetic beads can be trapped and released conditionally by controlling the difference between the Stokes force induced by the fluid flow and magnetic force resulting from a permanent magnet. The permanent magnet of CoNiP alloy is electroplated. It is characterized to have the 1369 Oe of coercivity, 1762 Gauss of remanence, and 0.603MGOe of (BH)max. Through the experimental and numerical investigation, the magnetic beads are trapped under the flow velocity of 17 ${\mu}m/s$ and are released perfectly above the velocity of 174 ${\mu}m/s$.

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References

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