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http://dx.doi.org/10.3795/KSME-B.2007.31.4.392

Fabrication and Performance Evaluation of a Micro Separation Chip of Magnetic Beads Using Magnetophoretic Flow  

Go, Jeung-Sang (부산대학교 기계공학부, 부산대학교 기계기술연구소(RIMT))
Publication Information
Transactions of the Korean Society of Mechanical Engineers B / v.31, no.4, 2007 , pp. 392-397 More about this Journal
Abstract
We developed a microfluidic platform able to control the trap and release of magnetic beads used for separation of a specific biomolecules. The magnetic beads can be trapped and released conditionally by controlling the difference between the Stokes force induced by the fluid flow and magnetic force resulting from a permanent magnet. The permanent magnet of CoNiP alloy is electroplated. It is characterized to have the 1369 Oe of coercivity, 1762 Gauss of remanence, and 0.603MGOe of (BH)max. Through the experimental and numerical investigation, the magnetic beads are trapped under the flow velocity of 17 ${\mu}m/s$ and are released perfectly above the velocity of 174 ${\mu}m/s$.
Keywords
Magnetic Bead; Separation; CoNiP Alloy;
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Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By SCOPUS : 0
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