Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

Osteopromotive effect of Titanium Reinforced-ePTFE membrane

티타늄강화 차폐막의 골유도 재생 효과

  • Lee, Jean (Department of Periodontology, Kyung Hee University) ;
  • Kwon, Young-Hyuk (Department of Periodontology, Kyung Hee University) ;
  • Park, Joon-Bong (Department of Periodontology, Kyung Hee University) ;
  • Herr, Yeek (Department of Periodontology, Kyung Hee University) ;
  • Chung, Jong-Hyuk (Department of Periodontology, Kyung Hee University) ;
  • Kim, Chong-Kwan (Department of Periodontology, Research Institute for Periodontal Regeneration College of Dentistry and Brain Korea 21 project Medical Sciences, Yonsei University)
  • 이진 (경희대학교 치과대학 치주과학교실) ;
  • 권영혁 (경희대학교 치과대학 치주과학교실) ;
  • 박준봉 (경희대학교 치과대학 치주과학교실) ;
  • 허익 (경희대학교 치과대학 치주과학교실) ;
  • 정종혁 (경희대학교 치과대학 치주과학교실) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주조직 재생연구소, BK21 의과학 사업단)
  • Published : 2004.12.31
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Abstract

The purpose of this study is to evaluate the regenerated bone histollogically using titanium reinforced ePTFE(TR-ePTFE) membrane and to investigate cell occlusiveness, wound stabilization and tissue integration of TR-ePTFE membrane. Adult male rabbits (mean BW 2kg) and TR9W (W.L.Gore&Associate.INC,USA) were used in this study. Intramarrow penetration defects were surgically created with round carbide bur(HP long #6) on calvaria of rabbits. TR-ePTFE membrane was applied to defect. Then guided bone regeneration was carried out using TR-ePTFE membrane and resorbable suture. At 2,4,8,12 weeks after the surgery, animals were sacrificed. Nondecalcified specimens were processed for histologic analysis. The result and conclusion of this study were as follows: 1. TR-ePTFE membrane had good ability of biocompatibility and cell occlusiveness. 2. space making for guided bone regenerayion was good at TR-ePTFE membrane. 3. Tissue integration was not good at TR-ePTFE membrane. So, wound stabilization was not good. 4. At 8 weeks, 12 weeks after GBR procedure, bone formation was seen. From the above results, TR-ePTFE membrane fixed tightiy on alveolar bone might be recommended for the early bone formation.

Keywords

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