Korean Journal of Microbiology (미생물학회지)

The Microbiological Society of Korea (한국미생물학회)
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Fecal Microflora of Mice in Relation to Diet

식이에 따른 장내세균의 효소활성 및 장내세균층의 비교

  • Published : 1999.06.01
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Abstract

The effects of diet on the composition of fecal microflora in mouse and the aclivilies of several enzymes in the leces were investigated. Vegetarian dietary groups were found to contain about ten lines higher numbers of Locmbocillus and B$&bacterizml than animal dietary groups. An~rnal dietmy groups were found to contain about 5 tolo times higher numbers of anaerobic Closhidia and Bocieriocles than the vegeterian detary groups. Fccal microbial $\beta$-glucosidase, $\beta$-glucm'onidase, ii-yptophanase and orease activilies in ihe animal dietary groups were shown lo be 30 to 50% hgher than those in h e vegetarian detary groups.

식이에 따른 장내세균의 균총의 변화와 장내미생물의 효소활성을 비교하였다. 동물성 식이를 실시한 군에서는 식물성 식이를 실시한 군과 비교시 유해한 혐기성 균의 수가 약 10배 정도 많게 관찰되었으며, 식물성 식이를 실시한 군에서는 비피더스균이나 유산간균의 수가 동물성 식이를 실시함 군보다 10배 정도 많게 관찰되었다. 또한 대장암 발병과 상관관계가 깊은 것으로 알려진 장내미생물 유래효소활성을 비교한 결과 $\beta$-glucosidase, $\beta$-glucuronidae, tryptophanase, urease 등의 효소활성이 동물성 식이를 실시한 군에서 1.8배-2배 가량 높게 나타났다. 즉 식이에 따라 장내 세균총의 차이 및 장내세균의효소활성의 현저한 차이가 있음을 알 수 있었다.

Keywords

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