종격동 내배엽동 종양의 세침흡인 세포학적 소견

Fine Needle Aspiration Cytology of Endodermal Sinus Tumor of the Mediastinum

  • 조갑래 (계명대학교 의과대학 병리학교실) ;
  • 김상표 (계명대학교 의과대학 병리학교실) ;
  • 박관규 (계명대학교 의과대학 병리학교실) ;
  • 권건영 (계명대학교 의과대학 병리학교실) ;
  • 장은숙 (계명대학교 의과대학 병리학교실)
  • Cho, Kam-Rae (Department of Pathology, Keimyung University School of Medicine) ;
  • Kim, Sang-Pyo (Department of Pathology, Keimyung University School of Medicine) ;
  • Park, Kwan-Kyu (Department of Pathology, Keimyung University School of Medicine) ;
  • Kwon, Kun-Young (Department of Pathology, Keimyung University School of Medicine) ;
  • Chang, Eun-Sook (Department of Pathology, Keimyung University School of Medicine)
  • 발행 : 1993.06.30

초록

Endodermal sinus tumor of the mediastinum is a very rare malignant tumor, usually affecting young adolescents, and its histologic findings are characteristic as that of gonadal germ cell origin. We describe the cytologic finding of fine needle aspiration of mediastinal endodermal sinus tumor in a 19-year-old male patient, comparing with tissue section. The tumor cells in smears were usually in tight clusters with large overlapping cells, which were arranged in a papillary or microacinar pattern, suggesting carcinoma. The tumor cells were large, round or oval with a small amount of cytoplasm which was occasionally vacuolated and had indistinct border. The nuclei were large, pleomorphic, and vesicular with large prominent nucleoli. The tissue sections showed typical findings of endodermal sinus tumor. Careful correlation of cytological findings and the serum alpha -fetoprotein level would be helpful to confirm the diagnosis.

키워드