• Title/Summary/Keyword: Aspiration cytology

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Validity of Frozen Biopsy during Thyroidectomy (갑상전 절제술시 동결절편조직검사의 유용성에 대한 평가)

  • Kim Seong-Yeal;Kim Jung-Gu;Choi Young-Sik
    • Korean Journal of Head & Neck Oncology
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    • v.14 no.1
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    • pp.81-87
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    • 1998
  • Fine needle aspiration cytology was used widely to select thyroid nodules for surgery. The result could be highly reliable for most malignancies and for benign nodules. The purpose of this study was to determine the value of frozen biopsy by directly comparing the results of preoperative fine needle aspiration cytology to frozen biopsy examination. In our university hospital, 103 patients with thyroid nodule were operated during the years 1996 through 1997. A comparison of accuracy of the fine needle aspiration cytology with frozen biopsy was made for 85 patients who underwent both procedures. The 85 patients were separated into two groups. The group I included 65 patients, whose preoperative fine needle aspiration cytology results were reported as benign or malignant lesion definitely. The group II included 85 patients, the patients whose reported fine needle aspiration cytologic result was suspicious for malignancy were regarded .as malignant lesion and results for follicular neoplasm were regarded as benign lesion. The accuracy of both procedures was compared on two group also. The sensitivity, specificity, and accuracy of frozen biopsy were 76.7%, 93.5%, and 85.2% in group I and 75.6%, 95.5%, and 85.9% in group II, respectively, compared with 63.3%, 87.1%, and 75.4% in group I and 65.4%, 81.8%, and 72.9% in group II for fine needle aspiration cytology. On benign lesion, the accuracy was 95.5% in frozen biopsy and 68.2% in fine needle aspiration cytology, 75.6% in frozen biopsy and 53.7% in fine needle aspiration cytology on malignant lesion. We conclude that although fine needle aspiration cytology is the reliable diagnostic test in the evaluation of thyroid nodule, frozen biopsy should be performed intraoperatively, because fine needle aspiration cytology is insufficiently sensitive for reliable surgical planning.

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Diagnostic Accordance Rate and Accuracy Between Cytological and Histological Test in Lung Disease (폐질환에 있어 세포검사와 조직검사의 진단 일치율 및 정확도에 대한 조사 연구)

  • Kim, Sung-Chul;Ro, Joung-Whan;Kim, Tai-Jeon
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.4
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    • pp.189-195
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    • 2009
  • Lung cancer is a type of cancer with high mortality; its 5-year survival rate is at a low 14%. Related cytological tests include sputum, bronchial brushing, bronchial washing and fine needle aspiration cytology test etc. From the test specimens in which sputum, bronchial brushing, bronchial washing, and fine needle aspiration cytology were performed, the sensitivity, specificity and accuracy between cytology test and histology test. In the sputum test, sensitivity was 27.71% and specificity was 98.02%, and the bronchial brushing test showed sensitivity of 93.33% and a specificity of 91.3%. The bronchial washing test was a sensitivity of 53.7% and its specificity was 98.9%, and the fine needle aspiration cytology test showed sensitivity and specificity were 88.46% and 72.97%, respectively. In the specimens diagnosed as normal at the sputum test, malignant diagnosis was found in 21 specimens of bronchial brushing, 30 cases of bronchial washings and 37 cases of fine needle aspiration cytology specimens. In the specimens diagnosed as normal at the bronchial washing test, malignant diagnosis was found in 5 specimens of sputum, 7 specimens of bronchial brushin and 1 cases of fine needle aspiration cytology. One specimens found to be normal in fine needle aspiration cytology turned out to maligant in sputum test. The result of this research shows that, in diagnosis lung cancer, a test method of high sensitivity and specificity should be pursued. However, depending on the location and malignancy of the illness, diagnosis may not be obtained in some cases. Therefore, we conclude that the cytological tests performed for lung cancer testing such as sputum, bronchial brushing, bronchial washing, and fine needle aspiration cytology should be carried out in a mutually complementary manner.

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Fine Needle Aspiration Cytology of Metastatic Seminoma in Cervical Lymph Node - A Case Report - (경부 림프절에 전이한 정상피종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Jang, Kee-Taek;Park, Hye-Rim;Ahn, Jin-Seok
    • The Korean Journal of Cytopathology
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    • v.12 no.1
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    • pp.57-60
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    • 2001
  • Fine needle aspiration cytology of the cervical lymph node was performed in a 63-year-old man who had had an orchiectomy for seminoma one year ago. The tumor cells were arranged in loose clusters, occasional sheets, or single cells. The nuclei were round to ovoid with fine or reticular chromatin, and had one or more prominent nucleoli. These cells were intermingled with lymphocytes in a characteristic foamy, lacelike background. Documented reports of the cytologic appearance of the seminoma are rare, especially in the metastatic lesion. The diagnosis of primary gonadal seminoma by fine needle aspiration cytology is probably not indicated since the treatment of primary gonadal tumor requires surgical resection. Because of the characteristic cytologic features, fine needle aspiration cytology may be helpful in evaluation of the extent of tumor spread in the patients with testicular tumors.

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A Case of Benign Parotid Tumor Misdiagnosed for Parotid Cancer on Preoperative Cytology (수술 전 세침흡인세포검사에서 악성으로 의심되었던 이하선 양성 종양 1예)

  • Lee, Eun Jung;Hwang, Hye Jin;Byeon, Hyung Kwon
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.9-13
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    • 2015
  • Fine needle aspiration cytology as a diagnostic workup of parotid gland tumor is a simple and useful method. Although fine needle aspiration cytology could not predict accurate diagnosis in all cases, it is usually helpful in differentiating malignancy and benign lesions. A 35-year-old female was found to have a parotid mass for 1 year. Preoperative evaluation including computed tomography and magnetic resonance imaging were non-diagnostic, but, fine needle aspiration cytology on parotid mass showed the suspicion of a low-grade mucoepidermoid carcinoma. Superficial parotidectomy and selective neck node dissection were done based on cytology. However, final pathological examination confirmed benign pleomorphic adenoma. Here, the diagnostic accuracy and cautions in interpretation of result of fine needle aspiration cytology is discussed with respect to the case.

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Fine Needle Aspiration Cytology of Ki-1 Positive Large Cell Lymphoma- A Case Report - (Ki-1양성 대세포림프종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kwon, Kye-Hyun;Kwak, Jeong-Ja;Jin, So-Young;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • v.4 no.2
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    • pp.127-132
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    • 1993
  • Ki-1 lymphoma is a sort of high grade large cell lymphoma and defined on the basis of the reactivity of the tumor cells with monoclonal antibody Ki-1. On fine needle aspiration cytology, the reported case is rare and the differential diagnosis is not easy, especially from undifferentiated carcinoma and Hodgkin's lymphoma. We experienced a case of fine needle aspiration cytology of Ki-1 positive large cell lymphoma in a 61-year old male patient. Fine needle aspiration cytology from the cervical lymph node disclosed hypercellular smears with large single cells on polymorphous lymphoid background. The tumor cells had abundant dense cytoplasm and large nuclei with Irregular profiles. Although most cells were mononuclear binucleated and multilobed/multinucleated cells were also seen Immunohistochemistry was done and revealed strong positive staining for Ki-1 antigen.

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A Case of Anterior Neck Hematoma Causing Tracheal Compression after Fine Needle Aspiration Cytology of the Thyroid Nodule (갑상선결절 세침흡인 세포검사 후 기관 압박을 초래한 전경부 혈종 1예)

  • Park Min-Ho;Cho Mun-Hyeong;Seo Kyoung-Won;Yoon Jung-Han;JaeGal Young-Jong
    • Korean Journal of Head & Neck Oncology
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    • v.21 no.2
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    • pp.170-173
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    • 2005
  • Fine needle aspiration cytology (FNAC) of thyroid gland lesions has become a routine diagnostic method. And fine needle aspiration cytology is considered a safe, reliable and cost-effective means of selecting thyroid nodules with risk for malignancy. However, fine needle aspiration cytology of the thyroid may cause hemorrhage, infection, or trauma to adjacent structures. Hemorrhage sufficient to cause tracheal compression has not been reported. So we present a case of anterior neck hematoma causing tracheal compression after FNAC of the thyroid nodule.

Fine Needle Aspiration Cytology of Medullary Carcinoma of the Breast - A Case Report (유방의 수질암종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Chun, Yi-Kyeong;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.57-60
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    • 1994
  • Medullary carcinoma (MC) of the breast is an uncommon histologic form of infiltrating ductal carcinoma and the cytologic features of MC are not well delineated. We recently experienced a case of fine needle aspiration cytology of MC of the breast. The characteristic cytopathologic features were cellular aspirate consisting of large, pleomorphic cells in background of many single to clusters of lymphocytes.

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Fine Needle Aspiration Cytology of Mucoepidermoid Carcinoma of the Lung -A case report- (폐에 발생한 점액표피양 암종 -1예 보고-)

  • Hong, Soon-Won;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.1 no.2
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    • pp.170-174
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    • 1990
  • The mucoepidermoid carcinoma is a rare tumor in the lung. A case of bronchial mucoepidermoid carcinoma diagnosed by fine needle aspiration cytology is presented. The smear showed many intermediate cells with occasional mucus-secreting cells. Malignant squamous cells were not present. The cellular arrangement of intermediate cells was overlapping and grouped in ball-like fashion. These cytologic features are unique for diagnosis of this tumor.

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A Case of Hepatoma with Duodenal Metastasis Proved by Liver Aspiration Cytology and Gastrofiberscopic Duodenal Biopsy (십이지장 궤양으로 발현된 전이성 간세포암종 1예)

  • Kim, Sung-Jin;Park, Seok-Gun;Han, Dong-Sun;Kim, Sung-Sook
    • The Korean Journal of Cytopathology
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    • v.2 no.2
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    • pp.105-110
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    • 1991
  • We report a case of hepatoma with duodenal metastasis in a 53 year-old male patient. Hepatoma was confirmed by fine needle aspiration cytology technique, and duodenal metastasis by gastrofiberscopic biopsy. Duodenal metastasis of hepatoma is rare. We briefly review the role of fine needle aspiration cytology technique in diagnosis of hepatoma.

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Fine Needle Aspiration Cytology of Chondroblastoma Arising in the Rib - Report of A Case - (늑골에 발생한 연골아세포종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kwon, Kye-Hyun;Jin, So-Young;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.61-64
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    • 1994
  • Chondroblastoma is a benign bone tumor accounting for less than 1 % of bone tumor. It infrequently involves the flat bones, among which ribs are particularly rare. On fine needle aspiration cytology, the diagnostic smear consists of chondroblasts, osteoclast-like giant cells, and chondroid matrix. The cytologic hallmark to differentiate from other giant cell-containing lesions is chondroblasts. We experienced a case of chondroblastoma in a 13-year-old female. Fine needle aspiration cytology from the 5 th rib revealed dispersed chondroblasts and osteoclast-like giant cells on hemorrhagic background. Chondroblasts had round to oval nuclei with fine, evenly distributed chromatin and distinctive grooves or indentation. Their cytoplasm was well-defined.

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