Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference (한국윤활학회:학술대회논문집)
- 2004.11a
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- Pages.362-366
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- 2004
Adhesion Strength Measurement of Chondrocyte
연골세포 부착력 평가
- Lee K. Y. (Mech. Eng. Dept., Sejong Univ.) ;
- Park S. K. (Mech. Eng. Dept., Sejong Univ.) ;
- Shin Deahwan (SWRI, USA) ;
- Park J. C. (Biomedical Eng. Dept., Yonsei Univ.)
- Published : 2004.11.01
Abstract
Quantitative evaluation of substrates for cells is essential to understanding cell-material adhesive interaction and it is also necessary for the development of new biomaterials. Many cells on adhesive molecules will form an organization of actin into bundles and production of the large, highly organized structures termed focal adhesions. To better understand adhesion formations between cells and substrata, we have quantified the force required to displace attached cell. we allowed rabbit knee chondrocyte to attach on a substratum of microscope slide glass. Our results demonstrate that a force is required to detach cells is changed according to detachment time variation.