Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2004.06a
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- Pages.276-276
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- 2004
Establishment of Mouse Pluripotent Stem Cells Generated from Primordial Germ Cells
- Shim, Sang-Woo (Laboratory of Animal Reproduction, ARRC, Kon-kuk University, Infertility Clinic, Department of OB/GY, Kyung-Hee Medical Center) ;
- Song, Sang-Jin (Laboratory of Animal Reproduction, ARRC, Kon-kuk University, Laboratory of Reproductive Biology & Infertility, Samsung Cheil Hospita) ;
- Hosup Shim (Department of Physiology, School of Medicine, Dankook University) ;
- Lee, Bo-Yon (Infertility Clinic, Department of OB/GY, Kyung-Hee Medical Cente) ;
- Huh, Choo-Yup (Infertility Clinic, Department of OB/GY, Kyung-Hee Medical Cente) ;
- Hyuk Song (Laboratory of Animal Reproduction, ARRC, Kon-kuk University) ;
- Chung, Kil-Saeng (Laboratory of Animal Reproduction, ARRC, Kon-kuk University) ;
- Lee, Hoon-Taek (Laboratory of Animal Reproduction, ARRC, Kon-kuk University)
- Published : 2004.06.01
Abstract
Pluripotent stem cells have been generated from two embryonic sources. ES cells are generated from ICM of blastocyst stage embryos, and embryonic germ (EG) cells are generated from primordial germ cells (PGCs). Both ES and EG cells are pluripotent and present important characteristics such as high levels of alkaline phosphatase (AP) activity, multi-cellular colony formation, normal and stable karyotypes, continuously passaging ability, and the capability of differentiation into all three embryonic germ layers. (omitted)