• Title/Summary/Keyword: Re-closure

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Enhancement of Re-closure Capacity by the Intra-amniotic Injection of Human Embryonic Stem Cells in Surgically Induced Spinal Open Neural Tube Defects in Chick Embryos

  • Lee, Gun-Soup;Lee, Do-Hun;Kim, Eun-Young;Wang, Kyu-Chang;Lee, Won-Don;Park, Sepill;Lim, Jin-Ho
    • Proceedings of the KSAR Conference
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    • 2004.06a
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    • pp.275-275
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    • 2004
  • To evaluate the potential of the stem cell therapy as a method for prenatal management of spinal open neural tube defect (ONTD), the influence of embryonic stem cells injected into the amniotic cavity on the re-closure capacity of spinal ONTD was investgated. Spinal neural tube was incised open for a length of 6 somites using chick embryos of Hamburger and Hamilton stage 18 or 19. (omitted)

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Prevention of Abdominal Re-adhesions by Sodium Carboxymethylcellulose in Dogs with Abdominal Adhesions (개에서 복강유착시 Sodium Carboxymethylcellulose를 이용한 재유착의 예방)

  • 정종태;이경갑;장광호
    • Journal of Veterinary Clinics
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    • v.14 no.2
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    • pp.161-167
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    • 1997
  • This study was carried out to prevent the abdominal re-adhesions in dogs. Two randomized groups of dogs were subjected to scratch the ileal serosa. Routine abdominal closure was performed on two groups. Second laparotomy was performed one month later for the scoring of the abhesion formation. The adhesions were separated physically after the scoring of the adhesions. In control goup saline was instilled into abdomen and in treated group 1% sodium carboxymethylcellulose(SCMC) solution was instilled into abdomen before the abdominal closure. Third laparotomy was performed another month later to evaulate the adhesions. Reduced adhesion formation following the instillation of 1% SCMC was reported. 1% SCMC is recommended to prevent the re-adhesions as well as adhesions.

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Numerical investigation of supercavity geometry and gas leakage behavior for the ventilated supercavities with the twin-vortex and the re-entrant jet modes

  • Xu, Haiyu;Luo, Kai;Dang, Jianjun;Li, Daijin;Huang, Chuang
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.13 no.1
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    • pp.628-640
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    • 2021
  • To investigate the supercavity geometry and gas flow structure for the supercavities with two closure types under the different flow conditions, an inhomogeneous multiphase model with the SST turbulence model was established, and validated by experimental results. The results show that two distinct regions exist inside the supercavity, which include the downstream flow region along the gas-water interface and the reverse flow region. For the twin-vortex supercavity, the internal gas leaks from the supercavity boundary by two paths: the supercavity surface and the two-vortex tubes. Increasing Froude number leads to more internal gas stripped from the supercavity surface. Two types of gas loss exist for the re-entrant jet supercavity with high Froude number, one type is the steady process of gas loss, and the major gas-leaking path is the supercavity surface rather than supercavity closure region. The other type is the unsteady periodic ejection, and the gas cluster of periodic ejection is merely a small part of the gas stored inside the supercavity.

The analysis of the LSA Airpark of Metropolitan Area (수도권 지역 경량항공 이착륙장 분석)

  • Shin, Dai-Won;Kim, Woong-Yi
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.22 no.1
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    • pp.44-50
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    • 2014
  • In this study, we surveyed the operating status of the LSA Airpark in Metropolitan Area of Korea, and compared the Airfield Facilities Manual for the Air Leisure. We analyzed the problems of the closure and the currently used of the LSA Airpark, through site visits. We presented the re-usability for the closure LSA Airpark, the improvements for the currently used of the LSA Airpark.

The study of predictive performance of low Reynolds number turbulence model in the backward-facing step flow (후방계단유동에 대한 저레이놀즈 수 난류모형의 예측성능에 관한 연구)

  • Kim, Won-Gap;Choe, Yeong-Don
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.5
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    • pp.1661-1670
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    • 1996
  • Incompressible flow over a backward-facing step is computed by low Reynolds number turbulence models in order to compare with direct simulation results. In this study, selected low Reynolds number 1st and 2nd (Algebraic Stress Model : ASM) moment closure turbulence models are adopted and compared with each other. Each turbulence model predicts different flow characteristics, different re-attachment point, velocity profiles and Reynolds stress distribution etc. Results by .kappa.-.epsilon. turbulence models indicate that predicted re-attachment lengths are shorter than those by standard model. Turbulent intensity and eddy viscosity by low Reynolds number .kappa.-.epsilon. models are still greater than DNS results. The results by algebraic stress model (ASM) are more reasonable than those by .kappa.-.epsilon. models. The convective scheme is QUICK (Quadratic Upstream Interpolation for Convective Kinematics) and SIMPLE algorithm is adopted. Reynolds number based on step height and inlet free stream velocity is 5100.

Mixed Convection Heat Transfer in a Rectangular Enclosure with Various Outlets (좁은 환기구를 가진 사각공간에서의 혼합대류 열전달)

  • Lee, C.J.;Chung, H.S.;Kwon, S.S.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.7 no.2
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    • pp.207-216
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    • 1995
  • Flow and heat transfer characteristics of mixed convection heat transfer in a rectangular en-closure with various outlets are numerically investigated. The parameters considered here include Reynolds number, Grashof number and the position of outlet. The results show streamlines, isotherms, Nusselt numbers, velocity and temperature distributions. It has been shown that as Reynolds number increases, the size of cell decreases at Re$\leq$100 and increases at Re>100 for $Gr=10^4$. There is a minimum size of cells at Re=100, $Gr=10^4$. The maximum mean Nusselt number occurs at Re=400, $Gr=10^4$ and one right outlet. The mean Nusselt numbers can be formulated by the correlation equation $Nu=C{\cdot}Gr^a{\cdot}Re^b$.

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A Study on the Delamination Growth in Composite Laminates Subjected to Low-Velocity Impact (저속 충격을 받는 복합 재료 적층판의 층간 분리 성장에 관한 연구)

  • 장창두;송하철;김호경;허기선;정종진
    • Journal of Ocean Engineering and Technology
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    • v.16 no.6
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    • pp.55-59
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    • 2002
  • Delamination means that cracking occurs on the interface layer between composite laminates. In this paper, to predict the delamination growth in composite laminates subjected to low-velocity impact, the unit load method was introduced, and an eighteen-node 3-D finite element analysis, based on assumed strain mixed formulation, was conducted. Strain energy release rate, necessary to determine the delamination growth, was calculated by using the virtual crack closure technique. The unit load method saves the computation time more than the re-meshing method. The virtual crack closure technique enables the strain energy release rate to be easily calculated, because information of the singular stress field near the crack tip is not required. Hence, the delamination growth in composite laminates that are subjected to low-velocity impact can be efficiently predicted using the above-mentioned methods.

Efficacy of a Novel Annular Closure Device after Lumbar Discectomy in Korean Patients : A 24-Month Follow-Up of a Randomized Controlled Trial

  • Cho, Pyung Goo;Shin, Dong Ah;Park, Sang Hyuk;Ji, Gyu Yeul
    • Journal of Korean Neurosurgical Society
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    • v.62 no.6
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    • pp.691-699
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    • 2019
  • Objective : Lumbar discectomy is an effective treatment for lumbar disc herniation (LDH); however, up to 2-18% of patients with LDH have experienced recurrent disc herniation. The purpose of this study was to evaluate the efficacy of a novel annular closure device (ACD) for preventing LDH recurrence and re-operation compared with that of conventional lumbar discectomy (CLD). Methods : In this prospective randomized controlled trial, we compared CLD with discectomy utilizing the $Barricaid^{(R)}$ (Intrinsic Therapeutics, Inc., Woburn, MA, USA) ACD. Primary radiologic outcomes included disc height, percentage of preoperative disc height maintained, and re-herniation rates. Additional clinical outcomes included visual analog scale (VAS) scores for back and leg pain, Oswestry Disability Index (ODI) scores, and 12-item short-form health survey (SF-12) quality of life scores. Outcomes were measured at preoperation and at 1 week, 1, 3, 6, 12, and 24 months postoperation. Results : Sixty patients (30 CLD, 30 ACD) were enrolled in this study. At 24-month follow-up, the disc height in the ACD group was significantly greater than that in the CLD group ($11.4{\pm}1.5$ vs. $10.2{\pm}1.2mm$, p=0.006). Re-herniation occurred in one patient in the ACD group versus six patients in the CLD group (${\chi}^2=4.04$, p=0.044). Back and leg VAS scores, ODI scores, and SF-12 scores improved significantly in both groups compared with preoperative scores in the first 7 days following surgery and remained at significantly improved levels at a 24-month follow-up. However, no statistical difference was found between the two groups. Conclusion : Lumbar discectomy with the $Barricaid^{(R)}$ (Intrinsic Therapeutics, Inc.) ACD is more effective at maintaining disc height and preventing re-herniation compared with conventional discectomy. Our results suggest that adoption of ACD in lumbar discectomy can help improve the treatment outcome.

Temporary Closure for Sternotomy in Patient with Massive Transfusion Might Be Lethal

  • Kim, Maru;Kim, Joongsuck;Kim, Sung Jeep;Cho, Hang Joo
    • Journal of Trauma and Injury
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    • v.30 no.1
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    • pp.12-15
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    • 2017
  • A 58-year-old male visited our emergency room for multiple traumas from explosion. On initial evaluation, hemopneumoperitoneum with liver laceration (grade 4) and colon perforation was identified. Hemopericardium with cardiac tamponade was also identified. Shrapnel was detected in the right ventricle. Damage control surgery was planned due to condition of hypotension. In operation room, control over bleeding was achieved after sternotomy, pericardiotomy, and laparotomy. Massive transfusion was done during operation. After gauze packing, operation was terminated with temporary closure (TC). Sanguineous fluid was drained profusely. Disseminated intravascular coagulopathy was confirmed through laboratory findings. No extravasation was discovered at hepatic angiogram. On re-operation, there was no active bleeding but oozing from sternotomy site was identified. Bone bleeding was impossible to control. Finally, reoperation was ended after gauze packing and TC all over again. The patient could survive for only a day after re-operation.