• 대한수의학회지
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• 제23권1호
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• pp.69-79
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• 1983

The present studs was undertaken to observe the histopathological changes on the cardiac and skeletal muscles, and liver of rabbits fed a commercial ration, either alone or with supplements of Zinc (3,000mg/kg. of diet, as sulfate), Copper (1,500mg/kg. of diet, as sulfate), Linoleic acid (3% of diet), Zinc with Linoleic acid and Copper with Linoleic acid. In the skeletal muscle, light microscopic changes observed were cloudy swelling, hyaline degeneration, atrophy, fragmentation and coagulative necrosis of muscle fibers, and proliferation of fibroblasts and infiltration of mononuclear cells. Especially, in rabbits fed with supplements of Zinc with Linoleic acid and Copper with Linoleic acid, calcification with muscle fibers progressing to necrosis were often observed. In the myocardium, loss of muscle fibers with necrosis and vacuolization, hyaline degeneration, hemorrhage and congestion were observed. In the liver, congestion and necrosis of hepatocytes, and centrilobular necrosis were observed. Differences of histological changes among the experimental groups was not marked.

• 대한수의학회지
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• 제25권2호
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• pp.145-148
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• 1985

Nickel toxicity and interactions of nickel with zinc, copper, and lead were studied in glowing chicks fed supplemented diet. Feed intake and growth rate of the chick were reduced by 250mg nickel as a sulfate salt per kg of feed. The toxicity of nickel was decreased by zinc or copper supplementation, but not lead. High nickel feed increased nickel level in kidney and decreased zinc levels in tibia and plasma. However, low zinc levels in tibia and in plasma were reversed by zinc supplementation. Hemoglobin, packed cell volume, and aortic elastin content were increased in chicks fed nickel. These results suggest that nickel toxicity is induced by interference with zinc metabolism.

• 자원리싸이클링
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• 제16권6호
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• pp.39-45
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• 2007

황동 전구 base 제조과정에서 발생하는 황산폐수에 함유된 구리와 아연의 농도를 저감시키기 위해 중화법에 의한 최적조건을 조사하였다. 구리와 아연이 함유된 황산용액에 대해 화학반응과 물질수지를 고려하여 용액의 pH에 따른 구리와 아연의 농도분포와 용해도를 구하였다. 구리와 아연의 수산화물이 침전되는 pH영역에서 아연의 용해도가 구리의 용해도보다 크므로, 구리에 비해 아연의 제거율이 용액의 pH에 민감하였다. 응집제로 $Al_2(SO_4)_3$를 첨가하는 경우 아연의 제거율은 응집제의 첨가형태에 영향을 받지 않았으나, 구리의 경우에는 용액으로 첨가하는 것이 고체상태로 첨가하는 것보다 제거율이 높았다.

• 대한수의학회지
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• 제52권2호
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• pp.115-124
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• 2012

Colorectal cancer (CRC) is one of the leading causes of cancer death in western countries or in the developed countries. Zinc intake has been associated with decreased risk of CRC. We investigated the effect of zinc on the formation of colonic aberrant crypt foci (ACF) induced by azoxymethane followed by dextran sodium sulfate in mice. Five-week old ICR mice were fed with the different zinc levels (0.01, 0.1, 1 ppm) for 12 weeks. The numbers of ACF were measured in the colonic mucosa. The ACF number of HZn group was significantly low compared with LZn group or MZn group. Cytosolic superoxide dismutase activity was the highest in HZn group, while thiobarbituric acid reactive substance level for lipid peroxidation was the highest in LZn group. There was no difference in number of PCNA-positive proliferative cells among the groups. TUNEL-positive apoptotic cells were increased in HZn group compared with LZn group. The HZn group exhibited a decrease of ${\beta}$-catenin immunostaining areas compared with the LZn or MZn group. These findings indicate that dietary zinc might exert a protecting effect against colon carcinogenesis by inhibiting the development of ACF in the mice.

• 상하수도학회지
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• 제13권2호
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• pp.47-54
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• 1999

SRB(Sulfate Reducing Bacteria) converts sulfate into sulfide using an organic carbon source as the electron donor. The sulfide formed precipitates the various metals present in the AMD (Acid Mine Drainage). This study is the fundamental research on heavy metal removal from AMD using SRB. Two completely mixed anaerobic reactors were operated for cultivation of SRB at the temperature of $30^{\circ}C$ and anaerobic batch reactors were used to evaluate the effects of carbon source, COD/sulfate($SO_4^=$) ratio and alkalinity on sulfate reduction rate and heavy metal removal efficiency. AMD used in this study was characterized by low pH 3.0 and 1000mg/l of sulfate and dissolved high concentration of heavy metals such as iron, cadmium, copper, zinc and lead. It was found that glucose was an organic carbon source better than acetate as the electron donor of SRB for sulfate reduction in AMD. Amount of sulfate reduction maximized at the COD(glucose)/sulfate ratio of 0.5 in the influent and then removal efficiencies of heavy metals were 97.5% of Cu, 100% of Pb, 100% of Cr, 49% of Mn, 98% of Zn, 100% Cd and 92.4% of Fe. Although sulfate reduction results in an increase in the alkalinity of the reactor, alkalinity of 1000mg/1 (as $CaCo_3$) should be should be added continuously to the anaerobic reactor in order to remove heavy metals from AMD.

• Asian-Australasian Journal of Animal Sciences
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• 제22권3호
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• pp.396-403
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• 2009

Male broiler chicks were fed graded levels of organic zinc (zinc-methionine) supplementation to investigate the effects of partial or complete substitution of the organic zinc source for inorganic ones on the development of lymphoid organs and immunological responses. A total of 450 day-old male broilers were distributed into groups of 10 chicks and randomly assigned to nine experimental diets during a 42-day feeding trial. Dietary treatments consisted of two basal diets supplemented with 40 mg/kg added zinc as feed-grade Zn sulfate or Zn oxide in which, Zn was replaced with that provided from zinc-methionine (ZnMet) complex at the levels of 25, 50, 75 or 100%. Two randomly-selected birds from each pen replicate were bled and then slaughtered by cervical cutting on the final day of the trial to measure leukocyte subpopulations and relative weights of lymphoid organs. Among lymphoid organs, only thymus weight was affected (p<0.05) by dietary treatments. The sulfate-supplemented birds were heavier (p<0.01) in relative weight of thymus than oxide-supplemented birds. The 10 days of age-assessed cutaneous hypersensivity reaction was stronger in chicks fed ZnMet-containing diets. Dietary ZnMet supplementation caused (p<0.05) an increase in proportion of lymphocytes and consequently a decrease in heterophil to lymphocyte ratio. Diet fortification by zinc-methionine complex increased (p<0.01) Newcastle antibody titer at 19 days of age. Also, a similar response was observed in antibody titers at 6 and 12 d after infectious bronchitis vaccine administration. There was no significant effect of replacement of dietary zinc on antibody titer against infectious bursal disease virus (IBDV) at the 6th d post-vaccine inoculation; however, at d 12 after vaccination, ZnMet-fortified diets improved antibody titer against IBDV. Although dietary inclusion of ZnMet had no marked effect on primary antibody titer against sheep erythrocytes, effective responses were observed during secondary reaction from the viewpoint of both total antibody and immunoglobulin Y (IgY) titers. From the present findings, it can be concluded that dietary supplementation with organic zinc improves both cellular and humoral immune responses. It is necessary to replace 75% of supplemental inorganic zinc with organic ZnMet complex to achieve the optimum immunological responses in broiler chicks.

• 한국표면공학회지
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• 제18권4호
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• pp.164-183
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• 1985

The microstructure of the zinc electrodeposits was investigated by changing the flow rate of electrolyte in zinc sulfate Bath. The cathode current efficiency increased with increasing flow rate of electrolyte. The preferred orientation of zinc electrodeposit changed from (11.2) texture to (10.3) or (10.1)+(10.2) texture with increasing current density in the range of flow rate, 0.2-1.2m/sec. The morphology of the deposits changed from the sponge deposit to the blocks of hexagonal crystallites packed together through the structures of find polycrystallite with increasing current density. The microstructure of the cross-section of the above deposits are granular structure and columnar structure respectively. The surface roughness of zinc electrodeposits decreased with increasing current density and flow rate of electrolyte.

• 한국식품위생안전성학회지
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• 제9권4호
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• pp.229-235
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• 1994

It is very important to investigate the sanitary chemical conditions of farmwaters used for cattle breeding in the dairy farms. For this purpose we examined pH, KMnO4 consumption, total hardness, chloride, sulfate, NH3-N, NO3-N, fluoride, lead, iron, manganese, cadmium, copper, zinc and chrome in the farmwaters sampled 2 times(spring and summer)in Choongcheongnam and Kangwon Province. The pH of farmwaters in Choongcheongnam and Kangwon Province was 6.49$\pm$0.09, 6.70$\pm$0.06, total hardness 90.21$\pm$7.07, 64.53$\pm$6.38 mg/ι, consumption of KMnO4 4.13$\pm$0.62, 4.34$\pm$0.26mg/ι, NO3-N 6.51$\pm$0.55, 3.61$\pm$0.58 mg/ι, chloride ion 20.51$\pm$1.99, 5.41$\pm$1.36 mg/ι and sulfate ion 6.61$\pm$1.02, 7.28$\pm$1.30 mg/ι, respectively. But NH3-N was scarcely detected. Fluoride, iron, lead, cadmium, zinc, manganese and chrome were not detected from the tested farmwaters. There was high significance between each other in total hardness, NO3-N, chloride ion and sulfate ion. There was regional and seasonal significance in only NO3-N but only regional significance in total hardness and chloride ion.

• Journal of Pharmaceutical Investigation
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• 제12권1호
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• pp.1-11
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• 1982

Silver sulfadiazine has been introduced to replace silver nitrate in the topical treatment of extensive burns and this drug exerts a prominent antibacterial action against Pseudomonas aeruginosa. The compound is painless upon application and insufficient sulfadiazine is absorbed to cause crystalluria. The primary purpose of the study was to clarify the antimicrobial action of zinc sulfadiazine ointment in comparison with silver sulfadiazine ointment as well as the pharmaceutical properties of the zinc sulfadiazine preparations. The results are summerized as followings: 1) The optimum ratio of two substrate compounds for the synthesis of zinc sulfadiazine are 2 moles of sulfadiazine and 1 mole of zinc sulfate at pH 6.0. 2) The stability of zinc sulfadiazine ointment preparation by using polyethylene glycol base, Beeler's base or polyoxyl 40 stearate base was more stable than that of silver sulfadiazine preparations. 3) The antimicrobial action of zinc sulfadiazine exhibits a stronger antimicrobial activity than that of sulfadiazine against Staphylococcus aureus but the opposite is true against Pseudomonas aeruginosa.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2000년도 춘계학술발표회 초록집
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• pp.37-37
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• 2000