• Carbon letters
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• v.10 no.2
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• pp.101-108
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• 2009

Various silanes, amino silane, vinyl silane, TESPD, and ZS (TESPD/zinc soap complex), are added into chlorinated isobutylene-isoprene copolymer (CIIR)/hard clay/carbon black (CB) compound and they are investigated with respect to the vulcanization characteristics, the processability, and the mechanical properties. In hard clay/CB filled system, only ZS silane added compound shows both lower Mooney viscosity and extrusion torque while vinyl silane added compound showed only a lower extrusion torque. All the ZS added compounds showed the lowest viscosity among them. The silane added compounds showed an increased modulus. In 'fatigue to failure' count test, the ZS added compound showed superior counts compared to other silane (amino, vinyl, TESPD) added compounds. The mechanical properties were significantly increased when the S2 and ZS were added into CIIR/hard clay/CB compound. The ZS added compounds showed a significant improvement on elongation modulus.

• Elastomers and Composites
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• v.39 no.4
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• pp.263-273
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• 2004

The effects of zinc surfactant (ZB) on the bis(triethoxysilylpropyl)disulfide (TESPD)-silica mixture in natural rubber (NR) and solution butadiene-co-styrene rubber(S-SBR) were compared with respect to their rheological property, processability, physical properties, and silica dispersion. In the NR compound, addition of the ZB increased the reversion resistance time (T-2), the tensile modulus, and the BO time; however, lowered the viscosity, the HBU, and tans values. In the S-SBR copound, addition of the ZB increased the $tan{\delta}$ values while lowered the T-2, the tensile modulus the BO time, the viscosity, and the HBU of the compound. In the NR compounds, addition of the ZB significantly increased the processability and mechanical property. However, in the S-SBR compounds, it improved the processability the mechanical property was not improved.

• Journal of Oral Medicine and Pain
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• v.32 no.3
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• pp.273-281
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• 2007

Zinc compounds have been used in various fields - cosmetics, medicine, and dentistry -because of its effective functions to human tissues or organs. Especially, it is well known that zinc has many biologic effects in oral cavity. Zinc ion can affect various oral microorganisms, resulting in reduction of oral bacteria, dental plaque, and dental caries. Also, zinc ion has an ability to reduce amounts of oral anaerobic bacteria and oral VSC and can reduce oral malodor. The author summarized the characteristics and toxicity of zinc, several forms of zinc compounds applied in human tissues, and reviewed biologic effects of Zinc in oral cavity (anti-bacterial effects, anti-plaque effects, anti-caries effects, and anti-VSC effects of zinc). Because of many advantages of zinc in oral cavity, it can be concluded that application of zinc compound to various oral diseases will be extended and activated, and promising.

• Journal of the Korean Chemical Society
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• v.38 no.5
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• pp.397-403
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• 1994

An activated catalyst prepared from a mixture of nickel nitrate hexahydrate with zinc in dry ethanol under reflux showed exceptional catalytic activity for the reduction of nitroarenes to the corresponding azoxy compounds exclusively in the presence of hydrazine monohydrate. However, when nickel nitrate hexahydrate was replaced by nickel chloride dihydrate with zinc, only the aminoarenes were formed in high yields. With unactivated catalyst, the reduction reaction from a mixture of nitroarenes, nickel nitrate or chloride, excess zinc and hydrazine monohydrate gave the corresponding azo, azoxy and amino compounds in much lower yields.

• Journal of the Korean institute of surface engineering
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• v.9 no.2
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• pp.1-7
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• 1976

The dissolving and growth kinetics of intermetallic compounds for the reaction between solid iron and molten zinc were studied under nitorgen atmosphere over the temperature range between470$^{\circ}C$ and 680$^{\circ}C$. The rates of dissolution of solid iron into molten zinc were obtained under a static conditon, The amount of dissolution of sold iron and the growth of intermetalic compounds could be determined by means of microscopy. The thickness of intermetallic compound at a given temperature increases with increasing time, whereas for a given time decreases with increasing temperature . The rate of dissolution is controlled by the diffusion process of iron in the effective boundary layer of molten zinc over the temperature range 470$^{\circ}$-530$^{\circ}C$, 570$^{\circ}$-620$^{\circ}C$, and 650$^{\circ}$-665$^{\circ}C$, while by the surface reaction over the range 530$^{\circ}$-570$^{\circ}C$ and 620$^{\circ}$-650$^{\circ}C$.

• Carbon letters
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• v.10 no.2
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• pp.109-113
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• 2009

Various silanes, amino silane, vinyl silane, TESPD, and ZS (TESPD/zinc soap complex), are added into chlorinated isobutylene-isoprene copolymer (CIIR)/soft clay/carbon black (CB). The vulcanization characteristics, the processability, and the mechanical properties are measured. In soft clay/CB filled CIIR system, there are no significant changes in Mooney viscosity among compounds. Vinyl silane added compound shows a low extrusion torque. All the silane added compounds shows an increased modulus. The mechanical properties are significantly increased when the S2 is added into CIIR/soft clay/CB compounds.

• Journal of Environmental Science International
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• v.5 no.3
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• pp.317-327
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• 1996

This study was performed to develop the biological treatment technology of wastewater polluted with heavy metals. Zinc-tolerant microorganism, such as Pseudomonas chlororaphis which possessed the ability to accumulate zinc, was isolated from industrial wastewaters polluted with various heavy metals. The characteristics of zinc accumulation in the cells, recovery of the zinc from the cells accumulating zinc, were investigated. Removal rate of zinc from the solution containing 100 mall of Zinc by zinc-tolerant microorganism was more than 90% at 48 hours after inoiulation of the microorganisms. A large number of the electron-dense granules were found mainly on thIn cell wall and membrane fractions, when determined by transmission electron microscope. Energy dispersive X- ray spectroscopy revealed that the electron-dense granules were zinc complex with the substances binding Heavy metals. The zinc accumulated into cells was not desorbed by distilled water, but more than 80% of the zinc accumulated was desorbed by 0.1M-EDTA. The residues of the cells after combustion at 55$0^{\circ}C$ amounted to about 21% of the dry weight of the cells. EDS analysis showed that the residues were comparatively pure zinc compounds containing more than 79% of zinc.

• Bulletin of the Korean Chemical Society
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• v.29 no.1
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• pp.76-80
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• 2008

Reductive acetylation of a variety of carbonyl compounds such as aldehydes, ketones and a,b-unsaturated enals/enones was carried out efficiently with pyridine zinc borohydride, (Py)Zn(BH4)2, in a mixture of THF-EtOAc at room temperature or under reflux condition. The corresponding acetates were obtained in high to excellent yields. In addition, chemoselective reductive acetylation of aldehydes over ketones was achieved perfectly with the reagent at room temperature.

• Bulletin of the Korean Chemical Society
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• v.18 no.10
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• pp.1100-1104
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• 1997

Compounds containing a nitrone moiety were designed, synthesized and evaluated as a new type of active site zinc ligating substrate analog inhibitors for carboxypeptidase A. The kinetic results indicated that they are competitive inhibitors for the enzyme, supporting the design rationale that the oxygen of the nitrone forms a coordinative bond to the active site zinc ion. The present study demonstrates that nitrone is useful as a zinc coordinating ligand in the design of inhibitors for zinc containing proteolytic enzymes.

• Journal of Integrative Natural Science
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• v.15 no.4
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• pp.171-177
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• 2022

ROS1 (c-ros oncogene) is one of the gene with mutation in NSCLC (non-small cell lung cancer). The increased expression of ROS1 is leading to the increase proliferation of cell, cell migration and survival. Crizotinib and Entrectinib are the drugs that have been approved by FDA against ROS1 protein, but recently patients started to develop resistance against Crizotinib and there is a need of new drug that could act as an effective drug against ROS1 for NSCLC. In this study, we have performed virtual screening, where compounds are taken from Zinc 15 dataset and molecular docking was performed. The top compounds were taken based upon their binding affinity and their interactions with the residues. The compounds stability and chemical reactivity was also studied through Density Functional theory and their properties. Further study of these compounds could reveal the required information of ROS1-inhibitor complex and in the discovery of potent inhibitors.