• Animal cells and systems
• /
• 제1권1호
• /
• pp.53-61
• /
• 1997

Seasonal variation of the population structure and the reproductive pattern of the Korean striped field mouse, Apodemus agrarius, were investigated. High capture ratios in juveniles, young adult, and old adult mice were found during the period from October to November, from November to March, and from May to September, respectively, and extremely low capture ratios of old adults during the period from November to February were characteristic. It seemed that the young adults that survived during the winter might become older by summer and have been counted as the old adults. The breeding in the mice began earlier in males (from mid February or early March to late October) than in females (from mid March to late October), having a peak in August and September, and both the male and female mice weighing more than 20 g generally reached sexual maturation in general. In the breeding season, both young and old adult males had large testes with enlarged seminiferous tubules filled with numerous germ and Sertoli cells, and expanded caudal epididymides with a vast number of spermatozoa; the females had many Graafian follicles and corpora lutea in large ovaries, and developed uterine glands in the thick endometria. The lower ratios of the testis weight to the body weight in July and August in 1994 compared to 1995 seemed due to the extreme drought and considerably higher temperature in 1994, but the decrease in the ratio in mid-summer, only in the old mice, in both years might be explained partially by aging.

• Journal of Microbiology and Biotechnology
• /
• 제34권3호
• /
• pp.580-588
• /
• 2024

Microbial communities in mangrove forests have recently been intensively investigated to explain the ecosystem function of mangroves. In this study, the soil microbial communities under young (<11 years-old) and old (>17 years-old) mangroves have been studied during dry and wet seasons. In addition, biogeochemical properties of sediments and methane emission from the two different mangrove ages were measured. The results showed that young and old mangrove soil microbial communities were significantly different on both seasons. Seasons seem to affect microbial communities more than the mangrove age does. Proteobacteria and Chloroflexi were two top abundant phyla showing >15%. Physio-chemical properties of sediment samples showed no significant difference between mangrove ages, seasons, nor depth levels, except for TOC showing significant difference between the two seasons. The methane emission rates from the mangroves varied depending on seasons and ages of the mangrove. However, this did not show significant correlation with the microbial community shifts, suggesting that abundance of methanogens was not the driving factor for mangrove soil microbial communities.

• 영미문화
• /
• 제18권2호
• /
• pp.27-50
• /
• 2018

Old age is often compared as climbing mountains which requires walking out of breath, yet with wider vision. And it is also likened to the estuary where the river flows slowly and broadly into the open sea. Socially, old age has been regarded as a symbol of wisdom and reflection, and elderly people often take the role of sage who leads the community. On the other hand, the dementia, gray hair and wrinkles of old age were sometimes perceived as the decline of intellect and vitality. Especially, in the digital age in which technology makes people more sensitive to physical artificiality, the evaluation of the old age becomes more complex and obscure. In other words, some elderly people can not escape from Confucious convention of the elders first, which causes the denouncement by younger generations. On the other hand, some elderly people are becoming more adaptable to the trend of young people, emerging as the new elderly people. The anti-aging movement, early adaptation of IT, bioengineering regimen also strong for the advanced age. However, as the new elderly people are active in many fields of society, they also face intergenerational conflicts in some areas where remains the overlap between young people and them due to the limited openings in economy and culture. This study is a transdisciplinary research which can be called old age humanities. First of all, this paper looks at the aspects of lifestyles and intergeneration conflicts in old age in four Korean and Western literary works about the old people, and also searches how to improve the quality of the later life of old people, Overall, this paper aims to explore the way the old people can achieve the full life with the help of intergenerational dependency through building aging humanities and new communities for old people.

• 한국노년학
• /
• 제39권2호
• /
• pp.199-211
• /
• 2019

본 연구는 노인을 전기노인과 후기노인으로 구분하고 선호하는 여가의 수행여부에 따른 여가만족도와 여가수행도의 차이를 비교분석하는데 목적이 있다. 분석을 위해 국민연금연구원의 제 6차 국민노후보장패널조사(KReIS) 부가조사 데이터를 이용하였다. 최종 분석 대상자는 전기노인 2,212명, 후기노인 1,985명으로 총 4,197명의 데이터를 분석하였으며 그 결과, 전기노인(6.83시간/7.39시간)에 비해 후기노인(7.64시간/7.81시간)의 주중 및 주말 여가시간이 증가하는 것을 알 수 있었다. 또한 참여하고 있는 여가활동유형은 전기노인과 후기노인에서 요일에 관계없이 휴식활동이 80%이상(TV 시청 및 라디오듣기 70% 이상)을 차지하였다. 선호여가 수행여부에 따른 여가수행도와 여가만족도 결과, 주중의 경우 선호하는 여가를 수행하고 있지 않은 후기노인의 여가수행도가 더 높았고, 주말의 경우에는 선호여가 수행여부와 관계없이 후기노인의 여가수행도가 높았다. 여가수행도의 경우에는 전기노인과 후기노인에서 수행도가 매우 높게 나타났으며, 여가만족도의 경우, 전기노인과 후기노인에서 모두 보통으로 응답하였고 전기노인의 여가만족도가 유의미하게 높았다. 여가변화요구도의 경우 선호여가 수행여부나 요일에 관계없이 전기노인의 여가변화요구도가 유의미하게 높게 나타났지만 두 집단의 응답 점수는 변화하고 싶지않음에 가까웠다. 이러한 연구결과를 바탕으로 전기노인과 후기노인의 여가만족을 향상시키고 여가수행을 지속하기 위한 여가제약요인을 고려한 프로그램 개발 및 건강관리제도 도입과 같은 실천적인 움직임이 이어야 할 것이다. 또한 전기노인과 후기노인의 여가활동 현황이나 유형분석에서 더 나아가 여가참여에 영향을 주는 주관적 요소 등의 질적인 측면을 고려한 체계적인 조사척도 연구의 필요성을 강조하고자 한다.

• 한국수정란이식학회지
• /
• 제33권4호
• /
• pp.305-311
• /
• 2018

Gonadotropin releasing hormone (GnRH) centrally plays a role in control of the hypothalamic-pituitary-gonadal axis-related hormone secretions in the reproductive neuroendocrine system. In addition, hormone receptors like luteinizing hormone receptor (LHR) are important element for hormones to take effect in target organ. However, ageing-dependent changes in terms of the distribution of GnRH neurons in the brain and LHR expression in the acyclic ovary have not been fully understood yet. Therefore, we comparatively investigated those ageing-dependent changes using young (1-5 months), middle (11-14 months) and old (21-27 months) aged female mice. Whereas a number of GnRH positive fibers and neurons with monopolar or bipolar morphology were abundantly observed in the brain of the young and middle aged mice, a few GnRH positive neurons with multiple dendrites were observed in the old aged mice. In addition, acyclic ovary without repeated development and degeneration of the follicles was shown in the old aged mice than others. LHR expression was localized in theca cells, granulosa cell, corpora lutea and atretic follicle in the ovaries from young and middle aged mice, in contrast, old aged mice had few positive LHR expression on the follicles due to acyclic ovary. However, the whole protein level of LHR was higher in the ovary of old aged mice than others. These results are expected to be used as an important basis on the relationship between GnRH and LHR in old aged animals as well as in further research for reproduction failure.

• Biomolecules & Therapeutics
• /
• 제29권4호
• /
• pp.399-409
• /
• 2021

1,2-Diacetylbenzene (DAB) is a metabolite of 1,2-diethylbenzene, which is commonly used in the manufacture of plastics and gasoline. We examined the neurotoxic effects of DAB in young and old rats, particularly its effects on hippocampus. Previously, we reported DAB impairs hippocampal neurogenesis but that the underlying mechanism remained unclear. In this study, we evaluate the toxicities exhibited by DAB in the hippocampi of 6-month-old (young) and 20-month-old (old) male SD rats by treating animals intraperitoneally with DAB at 3 mg/kg/day for 1 week. Hippocampal areas were dissected from brains and RNA was extracted and subjected to RNA-seq analysis. RNA results showed animals exhibited age-dependent sensitivity to the neurotoxic effects of DAB. We observed that inflammatory pathways were up-regulated in old rats but that metabolism- and detoxification-related pathways were up-regulated in young rats. This result in old rats, especially upregulation of the TREM1 signaling pathway (an inflammatory response involved in Alzheimer's disease (AD)) was confirmed by RT-PCR. Our study results provide a better understanding of age-dependent responses to DAB and new insight into the association between DAB and AD.

• 아동학회지
• /
• 제33권3호
• /
• pp.131-148
• /
• 2012

This study examines the scientific concept development of young children in terms of the day-night cycle. The subjects consisted of 180 three-, four-, and five-year-old children from two kindergartens and one children's center located in Seoul and Jeju. Individual interviews were conducted to collect verbal and pictorial responses on the day-night cycle. The scientific concepts on the day-night cycle are classified five stages including : no recognition, egocentric concept, initial mental models, synthetic mental models, and scientific mental models. Using two-way ANOVA, scores for the types of concept on the day-night cycles were then analyzed according to both the ages and genders of the children. The results reveal the existence of significant differences in terms of the types of concept of young children according to age. Most three-year-olds children had no recognition. Most three, four, and five-year-old children revealed egocentric concepts. Four-year-old children revealed that were in the initial stages of experiencing the mental models and synthetic mental models of the day-night cycle. Five-year-old children revealed that they were in the early stages of experiencing the initial, synthetic, scientific mental models of the day-night cycle. The results suggest appropriate ways of science education for young children based on the development of scientific concepts of the day-night cycle.

• 한국산학기술학회논문지
• /
• 제14권3호
• /
• pp.1342-1349
• /
• 2013

본 연구는 저소득 여성노인의 건강관련 삶의 질에 영향을 미치는 요인을 전기노인(65-69세), 중기노인(70-79세), 후기노인(80세 이상)으로 연령별로 구분하여 파악하고자 수행되었다. 자료는 B광역시의 5개 보건소의 맞춤형방문 보건사업에 등록된 기초생활수급자 여성 노인 383명으로부터 2010년 9월부터 11월까지 설문지를 통하여 수집되었으며 다중회귀분석으로 분석하였다. 저소득 여성노인의 건강관련 삶의 질, 생활 만족도, 인지기능, 허약수준은 연령별로 차이가 있었다. 저소득 여성노인의 건강관련 삶의 질에 영향을 미치는 요인은 연령별로 차이가 있었으며 생활 만족도, 인지기능, 허약수준, 주관적 건강수준, 만성질환개수를 포함한 모형은 전기노인의 건강관련 삶의 질을 42.8%, 중기노인의 28.9%, 후기노인의 31.5%를 설명하였다. 허약수준과 생활만족도는 저소득 여성노인의 전체 연령에 있어 건강관련 삶의 질에 영향을 미치는 요인으로 나타났다. 그러므로 저소득 노인여성의 건강관련 삶의 질 개선을 위한 건강증진 프로그램은 연령별 차이를 고려하여 개발되어 적용될 필요가 있다.

• 보건의료생명과학 논문지
• /
• 제8권2호
• /
• pp.155-163
• /
• 2020

본 연구는 국민건강영양조사 제7기 제3년도(2018년)원시자료를 바탕으로 한국전기-후기노인의 안전 의식 및 건강요인이 손상 및 손상기전에 미치는 영향요인을 알아보고자 하였다. 연구 대상자는 1년간 손상발생 여부에 응답한 전-후기노인 1608명을 최종 대상자로 하였다. 분석은 빈도분석, 교차분석, 다중 로지스틱회귀분석을 실시하였다. 연구결과는 노인은 성별, 결혼상태, 안전의식, 건강요인이 손상발생률과 관련성이 있으며, 전기노인은 여성일수록, 결혼상태가 별거 및 이혼 등의 상태일 때, 안전의식이 낮을수록, 2주간 몸의 불편감, 1달간의 와병여부, 1년간의 입원여부, 2주간의 외래 진료여부, 연간 미충족 의료서비스 경험이 있을수록 손상 발생율이 높았다. 후기노인도 여성, 별거 및 이혼 상태, 안전의식 수준이 낮고, 와병 여부, 입원여부, 연간 미충족 의료서비스 경험자일수록 손상발생률이 높았다. 따라서 손상사고 발생율을 낮추는 예방 교육으로 사회활동이 많은 전기노인은 교통수단 이용증가에 따른 맞춤형 안전교육, 후기노인은 건강행태에 따른 맞춤형 안전의식 고취 교육을 선별적으로 강화하고, 다양한 운송수단에 대한 음주운행 시 법적 처벌 강화, 교육의 통합 시스템적인 접근이 요구된다 하겠다.

• 한국노년학
• /
• 제39권4호
• /
• pp.699-721
• /
• 2019

주관적 기대여명(Subjective Life Expectancy)이란 자신의 수명에 대한 평가로, 주관적 인지평가에 그치지 않고, 건강한 삶을 위해 건강증진, 사회적 활동, 경제적 활동 등에서 실천적 행위를 하게 하는 기전으로 알려져 있다. 본 연구는 연령집단별 노인의 주관적 기대여명에 영향을 미치는 요인을 일반적 요인과 개입요인으로 나누어 파악하여 비교해보는 것에 목적이 있다. 연구대상자는 제 6차 고령화연구패널(KLoSA)을 이용하여 연령집단별로 연소노인(65세-74세) 2,106명, 중고령노인(75-84세) 1,803명, 초고령노인(85세 이상) 574명으로 총 4,483명이다. 일반적 요인은 통제변수로써 인구사회학적요인, 건강상태요인을, 개입요인은 독립변수로써 건강증진행위, 공적돌봄인지여부, 공식적 사회활동 참여, 일자리 및 소득보장 등에 해당하는 9가지의 변수를 설정하여 카이제곱검정, ANOVA, t-test, 위계적 다중 회귀분석을 실시하였다. 그 결과 주관적 건강상태와 기초연금은 모든 연령집단의 주관적 기대여명에 영향을 미쳤지만, 그 외의 변수들은 집단별로 차이가 있었다. 공식적 사회활동 참여, 일자리 및 소득보장요인은 연소노인과 중고령노인 집단에서 유의했고, 건강증진행위요인은 연소노인에서만 유의했다. 중고령노인은 다른 연령집단에 비해 개입요인보다 일반적 요인에서 유의미한 결과가 치중된 것으로 나타났다. 본 연구의 결과는 연령집단별 노인의 주관적 기대여명과 남은 노후를 잘 보내기 위한 실천적이고 개입 가능한 요인 탐색에 기초자료를 제공할 수 있을 것이다.