• 제목/요약/키워드: young-old

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In vitro Effects of L-Ascorbic Acid and Acrylamide on Lymphocyte Proliferation in Young and Aged Mice

  • Kang, Nam-Sung;Pyo, Suhk-Neung;Sohn, Eun-Hwa
    • Preventive Nutrition and Food Science
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    • 제15권1호
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    • pp.19-23
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    • 2010
  • This study examined the effects of Acrylamide (ACR) and L-ascorbic acid (AsA) on the proliferation of splenocytes and the mitogen-stimulated lymphocyte proliferation in young (8 weeks) and aged (82 weeks) C57BL/6male mice in vitro. AsA increased splenocyte proliferation in both groups; however, this effect was higher in old mice, while the proliferation of lymphocyte was decreased except for treatment at $1\;{\mu}g/mL$ low concentration in both mice. In addition, ACR treatment resulted in decreased LPS-induced B lymphocyte proliferation and ConA-induced T lymphocyte proliferation in both groups. However, AsA increased LPS/ConA-induced lymphocyte proliferation in young groups and had no effects in old mice except at $0.5\;{\mu}g/mL$ Thus, the present data indicate that there is no difference effect of ACR and AsA on lymphocyte proliferation, whereas the effect of AsA on mitogen-induced cell proliferation was reduced in old mice. Overall, our results suggest that various immunomodulators have differing effects of lymphocytic proliferation on young versus aged mice.

Ionescue-Shiley 조직판막의 환자 연령군에 따른 내구성에 관한 비교연 (Comparative Study of Durability of Bioprosthetic Valve Considering Age of Patients)

  • 김진국
    • Journal of Chest Surgery
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    • 제20권4호
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    • pp.673-682
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    • 1987
  • The principal feature of bioprosthetic valve which remains to be completely defined is long-term durability, especially, with regard to the impact of patient age. This report provides extended data regarding valve durability derived from a data base of 515 patients who received lonescu-Shiley bioprosthetic valve between 1978 and 1985; cumulative duration of follow-up was 1562.3 patient-years, with a maximum follow-up duration of 8.7 years. The results of this survey showed as follows: 1] The actuarial freedom from valve failure at 6 years were 43*7% for 0-19 year-old group, 70*1% for 20-39 year-old group and 75*1% for over 40 year-old group separately. 2] Of the causes of valve failure, only the primary tissue failure was markedly influenced by patient`s age [p<0.001], but the prosthetic valve endocarditis was not [p>0.1]. 3] The linealized incidences of primary tissue failure were 7.31% per patient-year in 0-19 year-old group and 0.12% in 20-39 year-old group. 4] The primary tissue failure rate in 0-19 year-old group was 6.36% during first 4 years, but then increased upto 10.95% at postoperative 5 year. Thus we find that in bioprosthetic valve the primary tissue failure is apt to occur when patient is young [especially less than 20 years old] and the postreplacement time passes [especially over 5 years]. The rate of bioprosthesis failure among children and adolescents is clearly higher than that observed in adult patients; however, conclusive quantification of time-related risk for young patient is not yet possible on the basis of existing data. Therefore, the advisability of bioprosthesis implantation in children remains to be determined.

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맹종죽의 죽령별 알칼리 펄프화 특성 (Alkali Pulping Charactics of Moso Bamboo(Phyllostachys pubescens Mazel) with Various Ages)

  • 윤승락;조현진;박병수;강하영;강규영
    • 펄프종이기술
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    • 제38권3호
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    • pp.29-37
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    • 2006
  • To use bamboo in the pulp industry, the anatomical characteristics of 60-day-old, 1-year-old, 2-year-old, and 3-year-old moso bamboo (Phyllostachys pubescens Mazel), and the characteristics of fiber and sheet of alkali pulp made of moso bamboo were investigated. Moso bamboo is composed of metaxylens and parenchyma cells in the inner part of the wall, and thick-walled small bundle sheathes near the outer walls. Moso bamboo showed the heterogeneity in anatomical structure. The longest fibers were shown in the middle part, and the widest width in the inner part. The lignin contents were 14.4% in 60-day-old bamboo, which was not lignified yet. The lignin contents in bamboo above 1 year were approximately 35%. The yields of alkali pulp of moso bamboo were in the range between 41 and 47%, and the yields tend to decrease with the increase of ages. The lignin contents of 60-day-old bamboo were 2.1% and those of bamboo above 1 year showed approximately 4% to 5% increment. The length, width, and curl index of fiber in alkali pulp appeared to be similar in all ages. However, coarseness increased slightly with the increase of bamboo ages. The distribution of long fiber was shown much in 60-year-old bamboo. The optical and mechanical properties of moso bamboo tended to decrease with the increase of bamboo age.

저년생 인삼의 잠아 및 화서형성에 관한 연구 (Study on the Forulation of Dormancy Bud and Inflorescence in Young Ginseng Plant)

  • 안상득;김요태
    • Journal of Ginseng Research
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    • 제11권2호
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    • pp.111-117
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    • 1987
  • 저년생 인삼의 잠아 및 화기형성시기와 양상은 고년생 인삼의 이차적인 양상과 상이하기 때문에 1년생 묘삼의 잠아발달 및 다식된 2년생 인삼의 화기형성과정을 조사관찰하였던 바 그 결과를 요약하면 다음과 같다. 1. 2년생 이상의 인삼 잠아조직은 4월중순경 분제조직의 조기포분제로 시작하는데 1년생 묘삼에서는 유근발근시인 3월 하순경 시작하는 것으로 추측되었으며 잠아의 위치는 자엽간 줄기하단 문부위에 생성되었다. 2. 3년생 이상의 인삼 화기분화는 전년도 형성된 뇌두조직내에서 형성되지만 2년생 인삼의 화기는 줄기선단 엽병사이의 경단분제조직에서 분제세포의 분열과 함께 분화, 형성되었다.

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공공서비스로서 신.구도심지의 공원만족도 차이 - 대전광역시를 대상으로 (Differences of Park Satisfaction in New and Old Downtown as Public Service; Focused on the City of Daejeon)

  • 심준영;이시영
    • 한국지역사회생활과학회지
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    • 제20권4호
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    • pp.481-491
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    • 2009
  • The purpose of this study was to evaluate the urban park and the green spaces within the public service framework. It was investigated by identifying the priority elements as defined by the residents and to figure out the differences of residents' satisfaction for the parks in new and old downtown. This study surveyed 455 residents from 80 dong (neighborhoods) of 5 Gu(districts) in Daejon. In this study, satisfaction on the urban parks and the green spaces in the old downtown was compared with the new town area. The results were as follows: Those who lived in the new downtown areas showed higher satisfaction than those in the old downtown for the urban parks and the green spaces, as well as in all 8 other evaluation sections. Both new and old downtown residents scored high on the 'city landscape and the natural environment' and 'green spaces and facilitats' items, but scored low on 'citizen's respect' and 'acceptance of resident opinions'. The old downtown residents highly valued on easy access to the parks, while the new downtown residents focused on various activities and programs, as well as resident participation, as the parks. The variables affected the resident's satisfaction on the urban parks in old downtown areas consisted of 'information', 'diversity', 'supply decision'. Among these variables, 'diversity' had the most significant influence on the satisfaction level.

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육계의 종류 및 체중별 도체율과 영양성분 및 적정가격에 관한 조사연구 (Studies on the Carcass Rates, Natrient Contents and Optimum Prices of Broilers and Old Layers as Related to Body Weight)

  • 이상진;이규호;오봉국;오세정
    • 한국가금학회지
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    • 제12권2호
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    • pp.113-118
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    • 1985
  • 본 조사연구는 육계의 종류 및 체중별 도체율, 부분육비율, 영양소 함량 및 적정가격을 검토하기 위하여 육계의 종류별 및 체중별로 총 240수를 공시하여 조사한 결과는 다음과 같다. 1. 도체율은 브로일러 및 노계에서 모두 체중이 무거울수록 높아지는 경향을 보여, 브로일러에서 영계(0.6-0.8kg)는 61.41%, 세미브로(1.2-1.4kg)는 65.07%, 하이브로 (1.7-2.1kg)는 66.39%였고, 노계에서 백색노계(1.8-2.0kg)는 62.68%, 유색노계(2.1-2.4kg)는 63.07% 였으며, 노계는 브로일러보다 도체율이 낮았다. 2. 부분육의 생산비율은 육계의 종류 및 체중에 따라 큰 차이를 보이지 않았으며, 비율이 높은 순서는 다리, 가슴, 등, 날개, 목의 순서였다. 3. 발골한 도체의 성분에서 브로일러는 체중이 무거워질수록 수분함량(%)이 감소(영계 71.27%, 세미브로 62.66%, 하이브로 60.39%)한 반면 지방함량은 증가(영계 11.47%, 세미브로 17.60%, 하이브로 19.87%)하였으나 단백질 함량은 세미브로(17.21%)가 영계(14.75%)나 하이브로(16.93%)보다 높았고, 노계는 백색과 유색노계간에 큰 차이가 없었다. 4. 육계의 생체kg당 가격에서 시중유통가격은 육계의 단백질함량기준 적정가나 단백질+지방함량 기준적정가와 비교하여 하이브로에 비해 세미브로는 높게 그리고 낮게 유통되고 있었다.

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Analysis of Ginsenoside Composition of Woods-grown Ginseng Roots

  • Han, Sung-Tai;Shin, Cha-Gyun;Yang, Byung-Wook;Hahm, Young-Tae;Sohn, Uy-Dong;Im, Byung-Ok;Cho, Soon-Hyun;Lee, Boo-Yong;Ko, Sung-Kwon
    • Food Science and Biotechnology
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    • 제16권2호
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    • pp.281-284
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    • 2007
  • The objective of this research is to provide basic information necessary to differentiate between ginseng (Panax ginseng) grown in woods environments and cultivated ginseng. The ginseng saponin (ginsenoside) contents of Korean woods-grown, 4 year-old cultivated, and 6 year-old cultivated ginsengs were determined via HPLC analysis. The total saponins in the woods-grown ginseng (0.648%) were approximately twice that of the 4 year-old cultivated (0.270%) and the 6 year-old cultivated ginsengs (0.280%). The protopanaxadiols (PD)/protopanaxatriols (PT) ratio of the woods-grown ginseng (3.258%) was higher than that of the 4 year-old cultivated (2.456%) and the 6 year-old cultivated ginsengs (2.183%). The $Rb_1/Rg_1$ ratio of the woods-grown ginseng (10.225%) was also higher than those of the 4 year-old cultivated (3.514%) and the 6 year-old cultivated ginsengs (4.865%).

배드민턴 동호인들의 참여 특성과 어깨 통증 및 장애 척도의 상관관계 연구 (The Effects of Badminton on the Shoulder and Its Correlation with the Shoulder Pain and Disability Index)

  • 오태영;하진영;이은지;김슬비;김부영;이해정
    • The Journal of Korean Physical Therapy
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    • 제25권1호
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    • pp.29-35
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    • 2013
  • Purpose: The purpose of this study was to investigate the correlation between shoulder pain and disability index (SPADI) with participation in badminton and to find the effects of badminton on the shoulder joint. Methods: A questionnaire was answered by 143 people with shoulder pain and disability in badminton clubs located in Busan, Gyeongsangnam-do. Out of the 143 subjects (91 males, 52 females), about half (72 people) were over 40 years old, with 71 people over 50 years old. The questionnaire contained 27 questions involving demographic participation characteristics, playing characteristics, and SPADI. Data analysis was performed using the SPSS statistics program to conduct frequency analysis, cross analysis, the t-test, and one-way analysis of variance. Results: The correlation between badminton career, frequency of play, and SPADI was statistically significant. There was a significant increase in SPADI scores for players over 40 years old. The over 40 year old group with less than 5 years of badminton had a significantly increase in SPADI score. The over 50 year old group showed a significantly lower SPADI score compared with the over 40 group. Conclusion: We suggest that beginner badminton players learn correct posture and badminton skills from professionals, participate regularly, and maintain an appropriate intensity/frequency of badminton.

Effects of $\beta$-glucans from Coriolus versicolor on Macrophage Functions in Young and Aged mice

  • Jang, Seon-A;NamKoong, Seung;Sohn, Eun-Hwa
    • 한국자원식물학회지
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    • 제23권6호
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    • pp.498-502
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    • 2010
  • The immune system may play an important role in aging and the changes in the immune status are associated with treatment of various immunomodulators. This study examined the effects of $\beta$-glucans isolated from mushroom fungi, Coriolus versicolor on macrophages functions in young (8-weeks-old) and aged (82-weeks-old) male C57BL/6 mice. When peritoneal macrophages were treated with various concentrations of $\beta$-glucan ($1-100\;{\mu}g/ml$) for 24 hrs, tumoricidal activity, NO production and phagocytic activity were significantly increased in the young mice, whereas there are no effects in the aged mice. These results suggest that $\beta$-glucans has differential effects on the macrophage functions in young and aged mice and age nutrition might need to be considered to select proper immunomodulator. In addition, $\beta$-glucan could be used clinically for the treatment of diseases such as cancer therapy in the young.

AGE AND GENDER DIFFERENCES IN ACUTE TOXICITY AND BLOOD-BRAIN BARRIER OPENING INDUCED BY SOMAN

  • Kim, Yun-Bae
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.112-112
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    • 2002
  • The age- and gender-related differences in acute toxicity and opening of blood-brain barrier induced by an organophosphate soman were investigated in rats. To assess acute toxicity, young (7 weeks old) and old (12 weeks old) male and female rats were subcutaneously administered with various dose levels of soman.(omitted)

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