• 한국자연치유학회지
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• 제10권1호
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• pp.56-65
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• 2021

목적: 본 연구는 아유르베다 사상을 통해 현대 서양 과학과 철학의 한계의 원인을 고찰하고, 치유사업 발전을 위한 홀리즘의 길을 모색하고자 하였다. 이에 현대 서양 문명이 오늘의 한계에 이르게 된 배경과 치유사업의 현실이 그맥을 함께 할 것이라 추론하였다. 방법: 이를 살펴보기 위해 동서양의 '몸과 마음에 대한 인식'의 차이와 '존재의 근원에 대한 관점'의 차이를 살펴보고 이에 따른 아유르베다 5원소설의 특징을 살펴보았다. 결과: 그 과정을 통해 서양의 '심신이원론'과 서양 4원소설에서의 '공(空)요소'의 부재'를 한계의 원인으로 지목하게 되었다. '공(空)요소'가 보이지 않는 세계, 비물질의 세계라는 점에서 공의 부재가 서양 문명의 한계인 동시에 국가 치유사업 현실의 문제라고 결론짓게 되었다. 결론: 본 연구가 아유르베다 사상의 지속적인 연구와 자연치유 분야의 연구로 이어져 치유사업의 발전의 기초정보가 되고, 국민의 건강과 웰빙·자기치유를 기대하여 본다.

• 문화기술의 융합
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• 제8권5호
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• pp.229-234
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• 2022

본 연구는 대학생을 대상으로 한 인문치유의 방법을 연구하고자 사전 설문조사를 실시하였다. 학생 설문조사를 바탕으로 인문치유의 연구 방향을 제시하고, 이에 적합한 인문치유의 방법을 찾고자 한다. 계량적인 분석을 위해 BPS-Modell, 몸(Bio), 정신(Psycho), 삶의 네트망(Sozio)을 중심으로 각 10문항을 구성하였다. 몸(Bio)에 대한 문항에서 50%의 학생들이 자신의 몸과 마음, 의지를 잘 파악하고, 그에 따른 행동을 하고 있다고 하였다, 그러나, 20%의 학생들은 자신의 몸과 마음, 의지에 따른 행동이 맞지 않는 것으로 나타났다. 정신(Psycho)에 대한 문항에서 50% 이상의 학생들이 자신의 내면과 소통이 잘 이루어진다고 하였다. 그러나, 20% 이하의 학생들은 잘 이루어지지 않는 것으로 나타났다. 삶의 네트망(Sozio)에 대한 문항에서 60% 이상의 학생들이 사회적 네트망을 잘 이루고 있다. 그러나, 10% 정도의 학생들은 삶에 대한 태도나 의미가 매우 낮은 것으로 나타났다. 인문학의 궁극적 목적은 '행복'이며, 인간 삶의 목적도 '행복'이다. 인문치유를 통해 안정적인 미래사회를 구현하고, 삶의 질을 높이는 긍정의 힘이 확대되기를 바란다.

• 대한약리학회지
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• 제7권1호
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• pp.53-65
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• 1971

It is well known that diabetes mellitus is associated with metabolic derangements, such as hyper-glycemia, ketosis, glycosuria, and also widespread alterations in the blood vessels, kidneys, eyes, peripheral nerves and heart. It is also recognized that healing of skin wound is delayed in diabetics. In bone, according to Aegerter, osteopenia develops in diabetes mellitus and it is chiefly ascribed to overutilization of protein. Shim claims that total blood flow to the entire skeletal system is approximately 4 to 8 percent of resting cardiac output and blood supply to the skeletal system would be decreased on account of secondary arteriosclerotic changes in the diabetics. An adequate blood supply is an essential factor in the healing process of fracture, and disturbed blood flow, either local or systemic, will invariably delay union of the fragments or the fragments from being fused. As the author has encountered several cases of diabetics in whom healing of fracture was delayed or incomplete, this experimental study was undertaken to elucidate the effects of hyperglycemia and diabetes mellitus on the healing process of fracture. In this experiment adult albino rabbits, weighing about 2 kg. were used and divided into 6 groups. The femur of each animal was fractured surgically, and then the healing process of fracture was periodically checked by radiography at an interval of one week for a period of 6 weeks. Thereafter, all the rabbits were killed to obtain tissue preparation of the femur. The experimental groups were as follows; 1) Control group: Six rabbits sustained a surgical fracture to the femur, without being given any other treatment or drug. 2) Alloxan-treated group: For inducing diabetes, alloxan was given intravenously to 17 rabbits in various dose as follows; to 7 of them 40 mg/kg, to 6 rabbits 80 mg/kg and to 4 rabbits 120 mg/kg of body weight, respectively. 3) Insulin-treated group: Protamine-zinc insulin was injected subcutaneously to each of 6 rabbits in a daily dose of 1 unit per kilogram of body weight. 4) Group treated with insulin after alloxan: Four rabbits were given 80 mg of alloxan once and than 1 unit of insulin per kilogram of body weight daily. Another 5 rabbits were injected 1 unit of insulin per kg of body weight daily following administration of alloxan in a dose of 120 mg/kg. 5) Homotransplantation group: Following intravenous injection of alloxan in a dose of 120 mg/kg, 10 rabbits underwent homotransplantation of a short bone segment to the femur. Five of them were subsequently given 1 unit/kg of insulin daily. 6) Sugar-treated group: six rabbits were fed $15{\sim}20$ gm of sugar daily throughout the period of experiment. The results obtained are summarized as follows; 1. Blood sugar level and damage to the pancreatic islet increased proportionately when alloxan was given to the rabbits in various doses. No appreciable change could be observed in the islets when the blood sugar level was altered by either oral administration of sugar or subcutaneous injection of insulin. 2. Comparing with the control group, healing of fracture was delayed in the alloxan-treated group, while callus formation and periosteal reaction were shown to be more prominent in this group and subsequently, the ultimate osseous tissue formed at the fracture site was significantly smaller in amount and less compact. These findings were more marked as the amount of alloxan increased. 3. Administration of insulin prevented the delay in healing process of fracture in the rabbits with alloxan-induced hyperglycemia. In this case, the course and progression of fracture healing were almost similar to those of control group. 4. Union between the host bone and the fragment transplanted from other rabbit of the same species was more delayed in the group treated with alloxan alone than in the group to which insulin was administered after development of alloxan-induced diabetes. In both groups periosteal new bone developed from the ends of the host bone, above and below the transplanted fragment, and directly fused with failure of periosteal callus to bridge the adjacent ends of the host bone and the transplanted fragment. 5. The healing process of fracture was not inhibited by alteration in blood sugar level when the blood sugar was abnormally increased by excessive sugar intake or lowered by administration of insulin alone. The healing of fracture in these groups progressed similarly as in the control group. In brief summary, it appears that the healing process of fracture would be definitely disturbed in diabetic state brought about by damage to the pancreatic islet. As such an inhibition could be overcome with insulin, it seems that insulin plays an important role in healing of fracture, but alteration in blood sugar level alone does not modify healing process of fracture to significant degree.

• Human Ecology Research
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• 제54권6호
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• pp.631-642
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• 2016

This study analyzed of the themes (wounding and healing); concerning the Sandplay therapy process applied to children with emotional instability and attention deficit problems. The subjects of the study were 30 elementary school children who agreed to a personal-interview with the author. They all were families of receiving basic livelihood welfare living in the same county. After the preliminary analysis, the main study data collected from subjects was analyzed by variance (t-test), frequency analysis, and correlation analysis using the standard table modified in accordance with Mitchell's classification system. Particular attention was made in the analyses of the characteristics of the subjects as members of low-income families. As the Sandplay therapy proceeded, it became evident that the wounding area showed a low frequency while the healing area featured a high frequency, and confirmed (as in previous studies) that the Sandplay therapy would be effective for children with emotional instability as well as for those with attention deficit problems. The analysis of difference between the types of children with both problems revealed that Sandplay therapy was more effective for children with emotional instability than for those with attention deficit problems. The analysis also revealed that Sandplay therapy was more effective for girls than for boys.

• The Korean Journal of Physiology and Pharmacology
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• 제10권3호
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• pp.143-147
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• 2006

Carthamus tinctorius L.is known to improve fracture healing, and bone morphogenetic proteins (BMPs) are associated with the formation and healing process of bone. BMP-2 and BMP-7 are two of the most important BMPs during the bone healing process. Human osteosarcoma MG63 cells and rats were used to determine the effects of Carthamus tinctorius L. extract (CTE) on BMP-2 gene expression. BMP-2 gene expression by CTE treatment in human osteosarcoma MG63 cells was not different from the control group until 8 hours of incubation, but was significantly higher, by 31%, than that of the control group at 16 hr of incubation. Microscopic findings of the 9th rib 3 weeks after fracture showed typical rimming of the osteoblast and immature bone formation in control and CTE groups. BMP-2 gene expression by in situ hybridization was remarkably increased by a CTE-supplemented diet in the fracture group compared to the control group. In conclusion, Carthamus tinctorius L. increased BMP-2 gene expression in human osteosarcoma cells and fractured bone. But further studies would be needed to elucidate the effect of CTE on fracture healing in vivo because our results did not show any evidence of healing improvement histologically $3^{rd}$ week after fracture.

• Archives of Plastic Surgery
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• 제34권3호
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• pp.285-290
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• 2007

Purpose: Many clinical trials have shown the effectiveness of platelet releasate on chronic wounds. However, a large volume of blood must be aspirated from a patient and a platelet separator is required. Here, we hypothesized that platelet concentrate obtained from a blood bank (PCBB) would be also effective at stimulating wound healing. The purpose of this study was to investigate the effectiveness of PCBB on accelerating healing of diabetic wounds in vivo. Methods: Round wounds of 5 mm diameter were made at four sites(two wounds on the left and two on the right side) on the backs of nine diabetic mice. Three hundred million platelets suspended in 0.05 ml fibrinogen were dispersed on each wound on left sides. Same amount of fibrinogen without platelets was dispersed on right side control wounds. Thereafter, 0.05 ml thrombin was applied to the each wound. Ten days after wound treatment, healed wounds were excised and the extent of wound healing in each group was compared. Results: Quantitative histologic analysis of epithelial gap distances revealed that PCBB treatment had greatly accelerated wound healing. Mean epithelial gap distances for PCBB treated and control wounds were $2.5{\times}0.6mm\;and\;3.6{\times}0.5mm$, respectively(p<0.05). Conclusion: Our results suggest that PCBB has potential to accelerate the healing of diabetic wounds.

• 셀메드
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• 제11권4호
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• pp.17.1-17.4
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• 2021

Episiotomy is the commonest obstetrics intervention in the world to reduce severe perineal injuries. Its prevalence is 43% to 100% in primiparous women in Asia. Further, worldwide approximately 10-95% of pregnant women undergo episiotomy incision during birth. Delay in wound healing probably increases the risk of wound infection, changes the muscular structure, and ultimately causes muscle tone loss. So, wound care is of specific significance to postnatal maternal outcomes. Hence, this case study aimed to evaluate the effect of Marham-i-Raal in episiotomy wound healing and pain relief. The study was conducted in eleven postpartum primi or multipara pregnant women aged between group 19 and 35 years with term gestational age, singleton pregnancy in a cephalic presentation who had a normal vaginal delivery with mediolateral episiotomy, without a perineal tear, and perineal hematoma. Externally, application of Marham-i-Raal 2g on episiotomy incisional wound, twice a day for 10 days was advised. Wound healing of episiotomy and pain intensity was assessed with REEDA ["redness, oedema, ecchymosis, discharge and approximation of the edges"] scoring and VAS scoring for pain intensity respectively. At one hour (baseline), the REEDA mean score of eleven patients was 3.90±1.04 whereas on day 7-10 it was 0.18±0.40 with statistically significant difference (p<0.001). The VAS mean score at one hour was 6.90±1.22 whereas on day 7-10 it was 0.72±0.78 with a statistically significant difference (p<0.001). Marham-i-Raal would be effective in episiotomy wound healing and reducing pain intensity. Further, randomized double-blind controlled trials in large sample size are recommended.

• 문화기술의 융합
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• 제9권4호
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• pp.105-112
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• 2023

본 연구는 영화 <라이프 오브 파이>(2013)을 통한 영화치유의 수업사례이다. 영화치유는 영화를 통한 동일시, 공감, 감정이입, 투사, 관찰학습 과정을 거쳐 진행된다. 연구를 통해 학생들은 영화 속 인물의 상황을 객관적으로 살펴보고, 이를 자신에게 동일시하고, 공감하게 된다. 학생들은 영화 속 인물의 상황을 평가하고, '내가 만약 주인공이라면 어떻게 할 것인지'에 대한 답을 통해 영화 속 인물이 당면한 고난을 간접 경험하고, 자신은 어떻게 할 것인가를 고민해본다. 주인공의 뛰어난 점을 동경하고, 자신의 삶을 성찰해본다. 이러한 과정을 통해 학생들은 자신의 감정과 문제의 상황을 살펴보고 해결할 수 있는 방법을 구체적으로 제시하게 된다. 결국 영화를 통해 학생들의 감정은 충분히 치유될 수 있는 것이다. 영화를 통한 치유는 치료자가 내담자를 고려한 영화선정에서 출발해야 한다. 이를 적용한 구체적인 방법도 충분히 제시할 필요가 있다. 영화치유의 방안은 앞으로 다양한 치유 방법의 제시로 더욱 발전할 수 있으리라 기대한다.

• 동의생리병리학회지
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• 제31권6호
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• pp.334-340
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• 2017

Wound healing is the restoration in injured skin tissue and one of the most important therapeutic targets. The process consists of inflammation, proliferation, and remodeling. There have been reported multiple factors that accelerate and delay wound healing. In this study we tested the hypothesis that Sophorae Radix extract would improve the recovery of wound healing after full-thickness skin wound in rats. Twenty young male Sprague-Dawley rats were used for the studies. A full-thickness skin wound was made on the dorsal skin of the rats. Either Sophorae Radix water extract (SR) or saline (Control) was orally administrated every day. The wound area was measured and the percentages of wound contraction, wound healed and wound epithelization were evaluated. After 15 days, the skin tissues were excised and examined by histopathological and immunohistochemistrical method. In results, wound area in SR group was significantly decreased to compared with Control. SR group showed the significant enhancements in the percentages of wound contraction, wound healed and wound epithelization. Histopathological examination revealed that SR induces neo-vascularization potential in wound healing process. SR treatment in rats significantly accelerated cutaneous wound healing in the angiogenesis process by increasing VEGF and TGF-${\beta}1$ synthesis. These results suggest that Sophorae Radix enhance skin wound repair by increasing the angiogenic agents such as VEGF and TGF-${\beta}1$.

• 한국전문물리치료학회지
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• 제6권3호
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• pp.1-10
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• 1999

The purpose of this study was to determine whether high voltage pulsed current stimulation (HVPCS) would enhance wound healing in neuropathic rabbits. Ten rabbits were assigned to either an experimental or a control group. The wounded part around the peripheral neuropathy of the experimental rabbits was stimulated for two hours twice a day for six days under the following conditions: pulse frequency 80 pps, pulse duration $100{\mu}s$, and stimulation intensity 30~40 V. The results indicated that there was no difference in the wound closure between the experimental and control groups. The two groups showed similar aspects in collagen and reticulum, which were observed by colored Masson's trichome. While the rabbits in the control group had more or less thick fibers, the rabbits in the experimental group had thin and branched-shape fibers. The rabbits in the experimental group showed both strong responses in the shaping of elastic fibers and the increased aspects in fibroblast when compared with the control group.