• CELLMED
• /
• v.4 no.1
• /
• pp.3.1-3.8
• /
• 2014

Spa represents a treatment widely used in many rheumatic diseases (RD). The mechanisms by which immersion in mineral or thermal water ameliorates RD are not fully understood. The net benefit is probably the result of a combination of factors, among which the mechanical, thermal and chemical effects are most prominent. Buoyancy, immersion, resistance and temperature play important roles. According to the gate theory, pain relief may be due to the pressure and temperature of the water on skin; heat may reduce muscle spasm and increase the pain threshold. Mud-bath therapy increases plasma ${\beta}$-endorphin levels and secretion of corticotrophin, cortisol, growth hormone and prolactin. It has recently been demonstrated that thermal mud-bath therapy induces a reduction in circulating levels of prostaglandin E2, leukotriene B4, interleukin-$1{\beta}$ and tumour necrosis factor-${\alpha}$, important mediators of inflammation and pain. Furthermore, balneotherapy has been found to cause an increase in insulin-like growth factor-1, which stimulates cartilage metabolism, and transforming growth factor-${\beta}$. Beneficial anti-inflammatory and anti-degenerative effects of mineral water were confirmed in chondrocytes cultures, too. Various studies in vitro and in humans have highlighted the positive action of mud-packs and thermal baths, especially sulphurous ones, on the oxidant/antioxidant system. Overall, thermal stress has an immunosuppressive effect. Many other non-specific factors may also contribute to the beneficial effects observed after spa therapy in some RD, including effects on cardiovascular risk factors (e.g. adipokines) and changes in the environment, pleasant surroundings and the absence of work duties.

• Journal of Korea Foundry Society
• /
• v.31 no.6
• /
• pp.362-365
• /
• 2011

In the present work, the corrosion properties of Mg-xSn (x = 1, 3, 5, 7 and 9 wt.%) alloys have been investigated. Potentiodynamic polarization and immersion tests were carried out in 3.5% NaCl solution of pH 7.2 at room temperature to measure the corrosion properties of Mg-xSn (x = 1, 3, 5, 7 and 9 wt.%) alloys. With increase of the Sn contents, the volume fraction of the $Mg_2Sn$ phase was increased. The corrosion rate of Mg-xSn alloys was increased up to 7 wt.%Sn and decreased above 9 wt.%Sn. Initiation of galvanic site during immersion mainly occurred at Mg/$Mg_2Sn$ interface and propagation went into ${\alpha}$-Mg. For this reason, corrosion properties of Mg-xSn (added from 1 wt.%Sn to 7 wt.%Sn alloys) alloys are decreased because the galvanic site was increased with increasing Sn addition. In Mg-9wt.%Sn alloy, however, the corrosion site were changed from Mg/$Mg_2Sn$ interface to ${\alpha}$-Mg/$M_2Sng$ interface in lamellar structure. Preferentially corrosion of ${\alpha}$-Mg/$M_2Sn$ interface in lamellar structure impeded corrosion propagation went into ${\alpha}$-Mg.

• Journal of the Korea Society of Computer and Information
• /
• v.15 no.2
• /
• pp.189-197
• /
• 2010

This study positively analysed the effects of service qualities of workers in integrated social welfare facilities on their working attitudes, targeting those who work for the welfare facilities. It identified the effects of service qualities such as tangibility, reliability, responsiveness, assurance, and sympathy on relationship factors such as relationship closeness through customization, organizational immersion and job satisfaction and presents suggestions to improve working attitudes of the workers. The results of the study are presented as follows: Reliability, responsiveness and assurance, service qualities of the workers, had effects on working attitudes. Relationship closeness through customization had an effect on organizational immersion and job satisfaction. Therefore, reliability, responsiveness and assurance that had effects on working attitudes of the workers were very significant factors and relationship closeness through customization were significant factors to improve working attitudes of the workers. This study presents political suggestions on the relations between service qualities of the workers in the welfare facilities and their working attitudes as alternatives.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.2
• /
• pp.337-346
• /
• 2016

Three combinations of molecular chaperones from Escherichia coli (i.e., DnaK-DnaJ-GrpE-GroEL-GroES, GroEL-GroES, and DnaK-DnaJ-GrpE) were overproduced in E. coli BL21, and their in vitro stabilizing effects on a nitrile hydratase (NHase) were assessed. The optimal gene combination, E. coli groEL-groES (ecgroEL-ES), was introduced into Rhodococcus ruber TH3. A novel engineered strain, R. ruber TH3G was constructed with the native NHase gene on its chromosome and the heterologous ecgroEL-ES genes in a shuttle plasmid. In R. ruber TH3G, NHase activity was enhanced 37.3% compared with the control, TH3. The in vivo stabilizing effect of ecGroEL-ES on the NHase was assessed using both acrylamide immersion and heat shock experiments. The inactivation behavior of the in vivo NHase after immersion in a solution of dynamically increased concentrations of acrylamide was particularly evident. When the acrylamide concentration was increased to 500 g/l (50%), the remaining NHase activity in TH3G was 38%, but in TH3, activity was reduced to 10%. Reactivation of the in vivo NHases after varying degrees of inactivation was further assessed. The activity of the reactivated NHase was more than 2-fold greater in TH3G than in TH3. The hydration synthesis of acrylamide catalyzed by the in vivo NHase was performed with continuous acrylonitrile feeding. The final concentration of acrylamide was 640 g/l when catalyzed by TH3G, compared with 490 g/l acrylamide by TH3. This study is the first to show that the chaperones ecGroEL-ES work well in Rhodococcus and simultaneously possess protein-folding assistance functions and the ability to stabilize and reactivate the native NHases.

• Journal of the Microelectronics and Packaging Society
• /
• v.16 no.1
• /
• pp.7-11
• /
• 2009

In this study, solder joints were made with Sn-3.5Ag (wt%) solder ball. Electroless nickel / immersion gold (ENIG) printed circuit board (PCB) substrates were employed in this work. The mechanical and electrical properties were measured as a function of the number of reflow. Die shear strength was measured with increasing reflow number. Until the forth or fifth reflow, shear force increased and after the fifth reflow the shear force of die decreased. The electrical resistivity of solder joint linearly increased with increasing reflow number.

• International Journal of Contents
• /
• v.16 no.4
• /
• pp.68-77
• /
• 2020

VR (Virtual Reality) contents make the audience perceive virtual space as real through the virtual Z axis which creates a space that could not be created in 2D due to the space between the eyes of the audience. This visual change has led to the need for technological changes to sound and sound sources inserted into VR contents. However, studies to increase immersion in VR contents are still more focused on scientific and visual fields. This is because composing and producing VR sounds require professional views in two areas: sound-based engineering and computer-based interactive sound engineering. Sound-based engineering is difficult to reflect changes in user interaction or time and space by directing the sound effects, script sound, and background music according to the storyboard organized by the director. However, it has the advantage of producing the sound effects, script sound, and background music in one track and not having to go through the coding phase. Computer-based interactive sound engineering, on the other hand, is produced in different files, including the sound effects, script sound, and background music. It can increase immersion by reflecting user interaction or time and space, but it can also suffer from noise cancelling and sound collisions. Therefore in this study, the following methods were devised and utilized to produce sound for VR contents called "A Midsummer Night" so as to take advantage of each sound-making technology. First, the storyboard is analyzed according to the user's interaction. It is to analyze sound effects, script sound, and background music which is required according to user interaction. Second, the sounds are classified and analyzed as 'simultaneous sound' and 'individual sound'. Thirdly, work on interaction coding for sound effects, script sound, and background music that were produced from the simultaneous sound and individual time sound categories is done. Then, the contents are completed by applying the sound to the video. By going through the process, sound quality inhibitors such as noise cancelling can be removed while allowing sound production that fits to user interaction and time and space.

• Corrosion Science and Technology
• /
• v.4 no.2
• /
• pp.39-44
• /
• 2005

The purpose of this work is to understand the effect of Mo addition on SSC susceptibility of high strength low alloy steels in terms of microstructure and corrosion property. Materials used in this study are high strength low alloy (HSLA) steels with carbon content of 0.04wt% and Mo content varying from 0.1 to 0.3wt%. The corrosion property of steels was evaluated by immersion test in NACE-TM01-77 solution A and by analyzing the growth behavior of surface corrosion products. SSC resistance of steels was evaluated using constant load test. Electrochemical test was performed to investigate initial corrosion rate. Addition of Mo increased corrosion rate of steels by enhancing the porosity of surface corrosion products. However, corrosion rate was not directly related to SSC susceptibility of steels.

• The Bulletin of The Korean Astronomical Society
• /
• v.40 no.1
• /
• pp.71.2-71.2
• /
• 2015

We present the high-resolution near-infrared spectra of standard stars observed with Immersion Grating Infrared Spectrograph (IGRINS). IGRINS covers the full spectral range of H and K bands simultaneously with a high spectral resolution (R=40,000), revealing many previously undetected and/or unknown lines. In this work, we present preliminary results of spectroscopic diagnostics for stellar physical parameters. Our ultimate goal is to provide a library of near-infrared spectra of standard stars, which covers all spectral types and luminosity classes, with a high-resolution and high signal to noise ratio ($SNR{\geq}200$).

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.6 no.1
• /
• pp.11-22
• /
• 2000

The paper describes creation methods of background scenes to implement realistic virtual environments in the VRSS (Virtual Reality Ship Simulator). VRSS is next-generation system constructed with virtual tools in a virtual space. Thus, it could have many benefits compared to conventional ship simulators composed with heavy bridge mock-up system and wide visual presentations. In this work, we developed effective 3D object modeling techniques, and constructed virtual harbor scene by using 3D-Webmaster authoring tool. The virtual harbor was built with object-oriented 3D objects modeled to interact with user's action. With the immersion-type VR system, we created virtual harbor environments in a virtual space, and discussed on the naturalness of the scene with test results of SDMPA (Semantic Differential Method for Psychophysical Assessment) by 10 subjects. As the results of subject assessment, all of the participants could felt natural-like harbor. Therefore, we found that the proposed creation methods and procedures of background scene are enabling to fit to the full mission VRSS construction.

• Proceedings of the KWS Conference
• /
• 2002.10a
• /
• pp.456-462
• /
• 2002

In the present work, a low cost and fine pitch bumping process by electroless Ni/immersion Au UBM (under bump metallurgy) and stencil printing for the solder bump on the Al pad is discussed. The Chip used this experimental had an array of pad 14x14 and zincate catalyst treatment is applied as the pretreatment of Al bond pad, it was shown that the second zincating process produced a dense continuous zincating layer compared to first zincating. Ni UBM was analyzed using Scanning electron microscopy, Energy dispersive x-ray, Atomic force microscopy, and X-ray diffractometer. The electroless Ni-P had amorphous structures in as-plated condition. and crystallized at 321 C to Ni and Ni$_3$P. Solder bumps are formed on without bridge or missing bump by stencil print solder bump process.