• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.815-822
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• 2015

Purpose: In this study, we aimed to evaluate the effects of sex-based non-small cell lung cancer (NSCLC) varieties on survival rates. Materials and Methods: A retrospective study was performed in patients with NSCLC who were diagnosed by histological methods between the years 2000 and 2010. A chi-square test was used to compare variables. Overall survival (OS) was estimated by the Kaplan-Meier method. Results: Of the 844 patients, 117 (13.9%) were women and 727 (86.1%) were men. Adenocarcinoma was more common in women than in men (p<0.0001). There were more women non-smokers than men (p<0.0001). There was no statistically significant difference in ECOG PS, weight loss>10%, stage, LDH, albumin and treatment between women and men. Women younger than 65 years (17.0 vs 12.0 months; p=0.03), who had adenocarcinoma histology (15.0 vs 10.0 months; p=0.006) and who had a hemoglobin level ${\geq}12g/dL$ (18.0 vs 12.0 months; p=0.01) were found to have a better median OS rate than men. Median OS rates were found to be 13.0 months in females and 12.0 months in males (p=0.14). Among metastatic patients, the median OS was 11.0 months in females and 8.0 months in males (p=0.005). Among stage IIIB and stage IV patients who had first line platinum-based chemotherapy, the median OS was 17.0 months in women and 11.0 months in men (p=0.002). The response rate of chemotherapy was higher in women than in men (p=0.03). Conclusions: In our study, we found that survival duration is longer and chemotherapy response is better in women with NSCLC who do not have anemia or comorbidities and who are mostly non-smokers with adenocarcinomas. Further studies regarding the causes of these differences may provide clarity on this subject.

• Journal of Chest Surgery
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• v.10 no.2
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• pp.183-189
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• 1977

There has been an alarming rise in the incidence of carcinoma of the lung in the world. The increase of the disease has been greater in men than in women, but even in women the rate has doubled in the last 20 years. During the 20 year period 1957 through 1976, 33 women with proven primary carcinoma of the lung were treated at Department of Thoracic Surgery, Seoul National University Hospital. During the period of survey, 170 consecutive cases of primary bronchogenic carcinoma were encountered in men, a male to female ratio of 5.2: 1. Ages of patients with bronchogenic carcinoma in women ranged from twenty-seven to sixty-eight years and most of them were over 40 years of age. The duration between the onset of symptoms and admission was about 9 months and the most common complaints were cough [66.6%], chest pain [60.6%], hemoptysis [48.4%] and dyspnea [45.4%]. Bronchogenic carcinoma developed most frequently in the upper lobes, and twelve [36.3%] of cases were squamous cell type, nine [27.2%] were anaplastic cell type, six [18.2%] were adenocarcinoma, one was alveolar cell type and five were unclassified type, in contrast to the usual predominence of adenocarcinoma among women in other reports. One half of the patients were inoperable and resection was feasible in only 24.2 per cent of the patients. There was no operative mortality but one case had bronchopleural fistula after pneumonectomy. Most patients with bronchogenic carcinoma in women were from large cities. Cigarette smoking appeared to be related to the occurrence of the squamous cell and anaplastic cell carcinoma because all heavy smokers had squamous cell or anaplastic cell carcinoma.

• Journal of Korean Public Health Nursing
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• v.22 no.2
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• pp.186-199
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• 2008

Purpose: To assess the health behavior practices and related factors among married women teachers. Methods: A descriptive correlation research design was employed. The subjects were 216 married women teachers who were conveniently sampled from 14 elementary schools, two middle schools and one high school. The data were collected using structured questionnaires and were analyzed via $x^2$-test, t-test, and logistic regression. Results: In terms of health behavior practices, 48.8% of subjects exercised more than once per week, 61.9% were consumers of alcohol, all of the subjects were non-smokers, 39.5% practiced healthy eating habit and 35.5% got an appropriate amount of sleep. In our logistic regression analysis, the significant factors affecting exercise practice were marriage years, and personality type. Factors affecting alcohol consumption were school grade and factors affecting eating habit were personality type, and school grade. Age was the only factor influencing adequate sleeping hours. Conclusion: We determined that each of the health behavior practices of married women teachers varied considerably in accordance with age, personality type, school grade, duration of work, and job stress, job satisfaction. The findings provide information that should be useful for the development of an integrated health promotion program for married women teachers.

• Journal of Preventive Medicine and Public Health
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• v.48 no.6
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• pp.280-286
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• 2015

Objectives: Approximately 10% to 15% of lung cancer cases occur in never-smokers. Hormonal factors have been suggested to lead to an elevated risk of lung cancer in women. This systematic review (SR) aimed to investigate the association between hormonal replacement therapy (HRT) and the risk of lung cancer in women using cohort studies. Methods: We first obtained previous SR articles on this topic. Based on these studies we made a list of refereed, cited, and related articles using the PubMed and Scopus databases. All cohort studies that evaluated the relative risk of HRT exposure on lung cancer occurrence in women were selected. Estimate of summary effect size (sES) with 95% confidence intervals (CIs) were calculated. Results: A total of 14 cohort studies were finally selected. A random effect model was applied due to heterogeneity (I-squared, 64.3%). The sES of the 14 articles evaluating the impact of HRT exposure on lung cancer occurrence in women indicated no statistically significant increase in lung cancer risk (sES, 0.99; 95% CI, 0.90 to 1.09). Conclusions: These results showed that HRT history had no effect on the risk of lung cancer in women, even though the sES of case-control studies described in previous SR articles indicated that HRT had a protective effect against lung cancer. It is necessary to conduct a pooled analysis of cohort studies.

• Journal of Korean Academy of Nursing
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• v.27 no.2
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• pp.315-328
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• 1997

The purpose of this study was to explore the process of smoking behavior of college women with a history of smoking. The subject were 48 female students selected by theoretical sampling from a womens' university in Korea. The data were collected by in-depth interviews using audiotape recordings done over a period of seven months. The data were analyzed simultaneously by a constant comparative method in which new data were continuously coded into categories and properties according to strauss and corbin's methodology. Analysis of the data resulted in identification of 15 categories representing 34 concepts. The results of this study were as follows : 1. Smoking in college women is caused by either curiosity or antagonism toward male smokers 2. The meaning(phenomena) of smoking behavior in college women is justifiable or regretable 3. Smoking occurs in connection with eating, during period of psychological conflict or as an habitual practice 4. Smoking behavior is related to the perception of harmfulness to health, influence of others and the accessability of cigarettes. 5. College women experinced a change in their state of health, emotional relaxation, change in their social relationships It is suggested that the results of this study may contribute to the development of strategies for the purpose of decreasing smoking behavior among female college students.

• Journal of Gastric Cancer
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• v.24 no.2
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• pp.145-158
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• 2024

Purpose: Although smoking and alcohol consumption are known risk factors for gastric cancer (GC), studies assessing their effects on early-onset GC are limited. In this nationwide, population-based, prospective cohort study, we assessed the effects of smoking and alcohol consumption on early-onset GC in patients aged <50 years. Materials and Methods: We analyzed data of patients aged 20-39 years who underwent cancer and general health screening in the Korean National Health Screening Program between 2009 and 2012. We calculated the adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for GC incidence until December 2020. Results: We enrolled 6,793,699 individuals (men:women=4,077,292:2,716,407) in this cohort. The mean duration of follow-up was 9.4 years. During follow-up, 9,893 cases of GC (men:women=6,304:3,589) were reported. Compared with the aHRs (95% CI) of never-smokers, those of former and current-smokers were 1.121 (1.044-1.205) and 1.282 (1.212-1.355), respectively. Compared with the aHRs (95% CI) of non-consumers, those of low-moderate- and high-risk alcohol consumers were 1.095 (1.046-1.146) and 1.212 (1.113-1.321), respectively. GC risk was the highest in current-smokers and high-risk alcohol consumers (1.447 [1.297-1.615]). Interestingly, alcohol consumption and smoking additively increased the GC risk in men but not in women (P_interaction=0.002). Conclusion: Smoking and alcohol consumption are significant risk factors for early-onset GC in young Koreans. Further studies are needed to investigate sex-based impact of alcohol consumption and smoking on GC incidence in young individuals.

• Journal of Korean society of Dental Hygiene
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• v.20 no.6
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• pp.855-864
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• 2020

Objectives: The aim of this study was to investigate the effects of periodontal disease in menopausal women. Methods: We used data from the 7th (2016-2018) Korea National Health and Nutrition Examination Survey. The subjects of the study were 2,643 women aged 40 to 59 years who participated in the periodontal examination and answered a menses questionnaire. The data were analyzed using complex samples multivariate logistic regression to investigate the effects related to periodontal disease in menopausal women. Results: After adjusting for general characteristics, oral health behaviors, and health status, those aged 50-59 years had odds ratio (OR) for periodontal disease of 2.52 compared to those aged 40-49 years. Compared to those who brushed 3 or more times a day, those with less than 3 brushings a day had OR of 1.48. Those who smoked had a 3.00 higher risk of periodontal disease than those who were non-smokers. Further, those with glycosuria had a 2.26 higher risk of periodontal disease than those without glycosuria. Conclusions: In order to promote the oral health of menopausal women, it is suggested that comprehensive and systematic oral health education should be implemented considering various variables.

• Korean Journal of Adult Nursing
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• v.28 no.4
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• pp.459-469
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• 2016

Purpose: This comparative descriptive study was to identify gender differences in delay seeking treatment and related experiences in patients with acute myocardial infarction (AMI). Methods: Ninety-seven participants were recruited from a tertiary hospital. Results: Mean age of 47 women was $71.5{\pm}13.3$ while that of men was $55.0{\pm}10.9$ (p<.001). More women lived alone and were jobless, less educated, and poorer than men. Men were likely to be 'current smokers' and drink alcohol, however viewed themselves healthier than women (p=.030). Women's hospital stay was $9.23{\pm}21.04$ days while men's was $4.86{\pm}2.72$ days (p=.014). More women had been diagnosed with hypertension (p=.040). Women appeared to report significantly less pain ($6.46{\pm}3.1$) than men ($8.44{\pm}1.8$). More men described their pain as sudden onset (p=.015) and chest pain as major symptom (p=.034) than women. More women were found alone upon onset of symptoms (p=.023) and had important reasons for delay seeking treatment (p=.021) than men. Median time from onset of symptoms to seeking medical service was 1.5 hours for men and 5.1 hours for women (p=.003). Median time taken from onset of symptoms to hospital for therapy was 3.5 hours for men and 9.1 hours for women (p=.019). Conclusion: This study findings that women reported less pain and delayed in seeking treatment, suggest needs for strategies targeting women at risk of AMI.

• Journal of Technologic Dentistry
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• v.28 no.1
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• pp.161-176
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• 2006

The purpose of this study was to evaluate smoking of dental technicians in 2005, and we have distributed questionnaires about smoking in 2005-KDTA general meeting and analyzed them. All 555 respondents who attended KDTA general meeting were selected by random sampling. However we dismissed 41 because of invalidness, so we got 504 people. Therefore, we have got conclusions below: 1. The rate of smokers who attended in 2005 KDTA was 33.93%, 46.3% in men, 1.44% in women. When we compared to other specialist groups, the rate of dental technician smokers was higher than them. 2. When we analyzed the ages of first smoking, 55.56% of the people started to smoke when they were in 24 years old. This result was very similar to the rate of dentist smokers in 2005 KDA research. 3. According to the answers of smokers and people who wire smokers in the past about quitting smoking period and willness in future, 60.82% among all members failed to quit smoking and also 69.2% among all members did not leap over 3 months but, they have thought to quit smoking for 6 months. 4. According to the answers about antismoking training related to environment in dental and clinical labs, most dental technicians(92.66%) have never been trained, also 37.70% among all members have not fulfilled their duty at self office. They have not recognized the danger of the indirect smoking. 5. When we asked chiefs in dental and clinical labs, the reason why they, didn't do the antismoking training their staffs, 32.1% of them replied that they were so busy, and 42.13% did because of their staffs, abhorrence and needlessness. 6. As Pan-dentistry members, over 80% agreed to the thought of the antismoking, also had medical knowledge about smoking. So we have the conclusion that dental technicians have identification as the Pan-dentistry members. 7. Most dental technicians expected KDTA to play a role about the antismoking training for their members. We have two suggestions to KDTA about the antismoking problem for members according to above conclusions. First, KDTA should prepare the antismoking training in the curriculum. Second, KDTA should support the antismoking programs of schools for students.

• Journal of Korean society of Dental Hygiene
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• v.7 no.3
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• pp.317-327
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• 2007

The purpose of this study was to examine the knowledge of dental hygiene students on smoking and their state of smoking in an attempt to assist dental hygienists to develop good anti-smoking education programs, as dental hygienists should play a critical role in conducting an anti-smoking campaign and education. The subjects in this study were dental hygiene students in six different colleges located in Seoul and Gyeonggi province. After a survey was conducted from April to June, 2007, the answer sheets from 1,322 students were gathered and analyzed. The findings of the study were as follows: 1. As for the reality of smoking, 82.7% were nonsmokers, and 12.2% had been smokers in the past, 5.1% were smokers, which accounted for 5%. Regarding when they started smoking, 47.1% and 35.3% started it in middle school and high school days respectively. So 80% or more began smoking as middle and high schoolers. As to a daily amount of smoking, 36.8% smoked five or less cigarettes, and 22.1% smoked six to 10 cigarettes, 14.7 % smoked 11 to 15 cigarettes. Concerning motivation of smoking, 51.5% did it out of curiosity, and 26.6% intended to get rid of stress. Among the smokers, 80.9% had ever tried to quit smoking, and as for the reason, 51.0 % wanted not to develop a disease in the future, and 25.0% weren't in good health. In regard to what made them fail to give up smoking, 49.0% answered they were increasingly stressed out, and 24.0 % were tempted by others. 2. As to the impact of smoking on the body and illness, the largest group believed it affected unborn babies, and the second largest group was aware of the harmfulness of secondhand smoking. The third largest group thought it exercised an influence on the lung and respiratory ailments, and the fourth largest group believed it was detrimental to health. The fifth greatest group thought tar was harmful to the body. They didn't know well about whether smoking deteriorated the sense of taste, but were well cognizant of the harmfulness of smoking. 3, Their knowledge on the impact of smoking on the body and diseases was evaluated by academic year and in consideration of whether they were smokers or not. And the largest number of them knew the best about smoking's impact on unborn babies and the harmfulness of secondhand smoking, regardless of academic year and whether they were smokers or not. They weren't well aware of its impact on weakening the sense of taste.