• Genomics & Informatics
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• 제10권1호
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• pp.16-22
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• 2012

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of multiple fluid-filled cysts that expand over time and destroy renal architecture. The proteins encoded by the $PKD1$ and $PKD2$ genes, mutations in which account for nearly all cases of ADPKD, may help guard against cystogenesis. Previously developed mouse models of $PKD1$ and $PKD2$ demonstrated an embryonic lethal phenotype and massive cyst formation in the kidney, indicating that $PKD1$ and $PKD2$ probably play important roles during normal renal tubular development. However, their precise role in development and the cellular mechanisms of cyst formation induced by $PKD1$ and $PKD2$ mutations are not fully understood. To address this question, we presently created $Pkd2$ knockout and $PKD2$ transgenic mouse embryo fibroblasts. We used a mouse oligonucleotide microarray to identify messenger RNAs whose expression was altered by the overexpression of the $PKD2$ or knockout of the $Pkd2$. The majority of identified mutations was involved in critical biological processes, such as metabolism, transcription, cell adhesion, cell cycle, and signal transduction. Herein, we confirmed differential expressions of several genes including aquaporin-1, according to different $PKD2$ expression levels in ADPKD mouse models, through microarray analysis. These data may be helpful in $PKD2$-related mechanisms of ADPKD pathogenesis.

• Journal of Information Technology Applications and Management
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• 제23권2호
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• pp.29-59
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• 2016

These days, the business environment such as Information Technology (IT) is rapidly changing, and organizations are consistently trying to change themselves for the survival and success under the changing environment. In this situation, change management is very important because it draws the change behaviors of organization members for the success of organizational change. The purpose of this study is to investigate the effect of the organization members' psychological factors on the performance of the acquisition of new IT, which is one of the most important organizational change. Based on previous studies in the area of organizational change, organization members' resistance to change, self-congruity theory, change activities and organizational performance, the research model is developed for validating the effect of organization members' self-congruity on the performance of the acquisition of new IT. Statistical analyses show that self-congruity has a significant effect on the change activities. In particular, private self-congruity has more impact on the change activities than public self-congruity. In addition, self-leadership, rewards and recognitions, and the diffusion of change activities have significant effects on job satisfaction. Self-leadership has a significant effect on organizational commitment.

• 보건교육건강증진학회지
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• 제26권3호
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• pp.35-48
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• 2009

Objectives: The community network is a foundation laid by the local community which has been formed historically and geographically to develop itself. This paper as a Korean way of healthy network survey for the community capacity building is an exploratory research to grasp the character of Korean society and then to organize an resident-governing partnership for that. Methods: Research objectives are CBOs(Community-Based Organizations) in S-district of Seoul. This region is a new town, however the solidarity and volunteerism of this resident is lively. The survey tool is Cho's CBOs Evaluation Questionnaire which was originated to measure the community capacity. The period of survey is from the January 2009 to the March 2009 and the study organizations which were collected by snowball sampling were 80. Results: The result shows two main networks: one is the civil society and craft union cluster, the other is welfare organization cluster. Groups of high centrality were organizations whose members are mainly women and craft organizations which were organized before 1990's. The group of high betweenness was the Association of Women's Organizations(0.188). Bi-components were six and they could be divided by organization's aim. In terms of the determinants of the participation to the health center enterprise, only the number of link(B=-0.60, p<0.04) was statistically significant. It means that when organization variables are controlled a tendency appears: the more the voluntary associations network, the less participation in the health enterprise. Conclusion: CBHOs(Community-Based Health Organizations) enhances residents' spontaneity and cohesion to increase the capability of the local community. If the surveyed healthy network, together the community health project, are used for various community development projects, the existing CBOs including CBHOs will be reorganized and furthered newly. For this it will be needed to construct an effective partnership of healthy network by restructuring the existing networks of voluntary associations.

• 헤리티지:역사와 과학
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• 제34권
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• pp.80-101
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• 2001

This article is concentrated on the organization for labor exchange in producing hemp cloth at Geumso-ri, Imha-myoun, Andong city. The organization is called "Sam-dool-ge", and it is different from the organization for labor exchange in producing rice because it is managed by women mostly. ln harvesting hemp, same amount of labor and expenses are invested. Especially, labor is supplied in equal condition. In spinning hemp cloth, the work is shared on the basis of same tech level. In threading the warp and fastening hemp cloth. the work conducted collaborately under the best engineer's direction. "Sam-dool-ge", a gil-sam labor exchange, also presents cultural creativity which produces and inherits the folkloric tradition, and also has the quality as a rite of passage. Nowadays, producing hem cloth is for pursuiting of profits than for making clothes as it used to be. This tradition will be lasted at least for a while because some young generations are beginning to participate in and old generation is teaching them good.

• 한국식생활문화학회지
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• 제29권6호
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• pp.668-676
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• 2014

The purpose of this study was to determine anthropometric measurements, dietary nutrient intakes, simple food intake frequencies, and rates of obesity in Cambodian women. A total 186 women, aged 20-69 years, living in Kampong Spue province of Cambodia and having the responsibility to prepare family meals participated in this study. Height and weight were measured body mass index (BMI) was calculated, and one-day 24-hour recall and food frequency questionnaires were conducted. In total, 18.8% were underweight, 49.5% were normal weight, 13.4% were overweight, and 18.3% were obese according to the World Health Organization BMI standard for Asians. No significant difference in height by obesity level was determined ($p{\geq}0.05$). The mean energy intake was 1571.2 kcal/day and protein intake was 43.6 g/day. There were significant differences in protein, niacin, and vitamin C intakes by obesity level (p<0.05). The prevalence of subjects consuming vitamins and minerals less than 75% of Recommended Dietary Allowances was 73-99%. All Cambodian women consumed rice ${\geq}1time/day$. Approximately 50% of subjects reported ${\geq}1time/day$ intake frequency of bread, cookies, and chips. In total, 35% indicated no intake of beans or bean products. For intake frequencies of carbonated beverages and sports drinks, there was a significant difference by obesity level (p<0.05). These results may be very helpful to prepare nutrition education programs for Cambodian women.

• 대한가정학회지
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• 제36권10호
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• pp.161-178
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• 1998

This study attemps to identify the factors related to dealing withy work-family conflict of employed women, and to investigate the needs and the methods of support for household labor. Especially, the results of this study aims to be reflected in women's policy from a political point of view. For these purposes, 477 married women those being employed (more than 30 hours per week) and having nuclear family were selected. Statistics were frequencies, means, percentile, and two-way ANOVA. The results were as follows. First, employed mother's housework time is 5 hours 16 minutes on a weekday and 9 hours 32 minutes on Sunday with the exception of market work time. And 84.5% of total housework was performed by housewife. Thus they take chage of work burden(market work and housework), and make a difficulties of cooking and family care. Seconds, the highest needs of support was the change of thought on division of labor, responsibility on housework, and status of women. The next were the needs of the social organization(flex-time, a special holiday for woman workers, home-based work) and the public institution(day-care center, school feeding). Thirds, contributing factors to the needs of support were housewife's age and occupation. So, this two factors were crossed in order to analyze family type by factors.

• 모자간호학회지
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• 제3권1호
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• pp.25-37
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• 1993

The purpose of this study was to investigate the relation between perception of family environment and mental health of boy's high school students. In order to obtain the appropriate data, a questionnaire was administered to 240 boy's high school 2nd-grade students in Pohang city from March 19 to March 28, 1992. The instruments used for this study were Moos's Family Environment Scale Form R and Kim's Symptom Check List-90. The conclusions were as follows : The level of perception of family environment was lower than mean score. Cohesion, achievement orientation, independence, organization, expressiveness were percepted high but active-recreational orientation, intellectual-cultural orientation were percepted low. Mental health of most respondents was well. The scores of obsessive-compulsive reaction and interpersonal sensitivity were high, the scores of somatization and phobia were low. General characteristic variables significantly related to the level of perception about family environment were father's occupation and mother's education level. There were no significant differences between general characteristic variables and mental health. There were mostly negative correlations between perception of family environment and mental health. Cohesion, expressiveness, independence, intellectual-cultural orientation, active-recerational orientation, moral-religious emphasis, organization were negatively correlated but conflict, achivement orientation, control were positively correlated. Cohesion, expressiveness, conflict, achivement orientation, active-recretional orientation, organization, control were significantly related, but independence intellectual-cultural orientation, moral-religious emphasis were no significant correlation.

• 대한간호학회지
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• 제30권5호
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• pp.1195-1206
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• 2000

The purpose of this study was to analyze womens' health problems using Green & Kreuter's 1991 PRECEDE model and to develop a model for a womens' health care center located in the community. The subjects were recruited from Wonju City. 1. The results showed that 23% of the sample population felt there was a need for a womens' health care center. The mean number of health problems was 3.1. The prevalence rate, was 44.4%, and the rate for an artificial abortion, was 36.4%. Also 30.5% did not have a health examination in the past year. Women using the hospital for medical care accounted for 45% of the sample, while 40% used the drugstore. The average score on the HPLP was 2.41, and this was influenced by self-efficacy, family support, sexual role, and health locus of control. There are a few educational programs in the city provided by the Wonju Health Center and by community health nurse practitioners. 2. The nursing center, as defined in North America, is a nurse-anchored system of primary health care delivery or neighborhood health center. Centers offer various services ranging from primary care to the more traditional such as education, health promotion, wellness screening, and coordination of services by advanced practice nurses. For examples in Sweden MCH centers provide total services for childbearing women and their families, sexual counseling and education for adolescents, and screening by midwives for cervical cancer. 3. The developed model combines purpose, target population, organization, and services, and is related to health resources. The purpose is primary health care and promotion of the quality of life. The target population can be grouped according to the life cycle, (premarriaged age group, the childbearing/child rearing age group, and middle aged and elderly women) and focuses on self-help. The organization of the center includes an advisory committee to plan and evaluate, and a health services team that will be multidisciplinary to provide health care, counseling education, and research. The model development suggested that a variety of women's health care centers are needed to insure adequate management of women's health. Follow-up research using PROCEED is needed to analyze health outcomes. Also a health nursing specialist system is required to develop health promotion, and improve the quality of life of women.

• Bulletin of the Korean Chemical Society
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• 제35권8호
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• pp.2281-2284
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• 2014

Polystyrene beads (PS beads) with narrow size distribution were synthesized, and their diameter was controlled from 1.2 to $5{\mu}m$ by varying the injection rate of a styrene solution containing initiator and the concentration of reactant, such as initiator and capping material. The diameter of the PS beads increased with increasing in the injection rates and the initiator concentration or decreasing the capping material concentration. Then, we used the PS beads as building block, and organized them into a hexagonally close-packed monolayer on substrate with template-assisted manual assembly. We showed perfect hexagonally close-packed organization of the PS beads with various sizes in large-scale area. And we demonstrated the superiority of the dry manual assembly over the wet self-assembly in terms of simplicity, speed, perfect ordering, and large scale.

• 패션비즈니스
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• 제6권2호
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• pp.1-16
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• 2002

The need for ready-to-wear clothing increases as the problem comes to arise from the fit of custommade clothing due to the characteristics of middle-aged women's somatotype. At this point of time, a study on the realities of production of custom-made clothing in middle-aged women's clothing business firms is of very greatly significance. Therefore, this study was intended to identify the problem and improvements through the survey research of production of custom-made clothing in middle-aged women's clothing business firms and further present the plan for development of custom-made clothing business. The questionnaire was framed based on the contents extracted from the preliminary questionnaire research for the pattern section chief of each business firm. Collected data were statistically processed using the SPSS 10.0 Windows program. As a result, the following findings were obtained: 1. The target age of the middle-aged women's clothing business firms ranged from more than 45 years to less than 50 years of age. Clothing business firms much made inroads into the ready-to-wear clothing market largely in the 1980s and the 1990s. Their active entry into the custom-made clothing market occurred in the 1970s and the 1980s. 2. In terms of the clothing production method of middle-aged women's clothing firms, some private boutique and designer brand clothing firms entered the clothing market with a focus on custom-made clothing in the beginning of its organization and introduced the production method of ready-to-wear clothing in accordance with changes in production methods and consumers' needs and wants. National brand clothing firms manufactured clothing with a focus on ready-to-wear clothing from the beginning of its organization, but at last they manufactured both partial custom-made and whole custom-made as the problem arose from ready-to-wear clothing. Seeing that their clothing production showed the ratio readyto-wear to custom-made clothing of 2.58:1. And it was found that the manufacture of ready-to-wear and custom-made clothing took into consideration the great difference in the pattern, size and design plan. The research of the clothing production process showed that whole custom-made and partial custommade were distinguished according to whether or not the sample was presented. 3. The ready-to-wear pattern of middle-aged women's clothing firms were used with a focus on the 'patternmaker-developed pattern' and company-developed pattern'. Most clothing businesses produced clothing in 4 to 5 basic sizes, which is found to be insufficient to complement the physical characteristics of middle-aged women with many specific somatotypes. In the pattern of custom-made clothing, the 'pattern of ready-to-wear were applied' or the 'customized pattern was developed'. Actual measurements were most used as the size of custom-made, and accordingly it is predicted that the level of satisfaction is higher with the fit of custom-made clothing than that of ready-to-wear. The selling place and the head office showed the similar percent as the place for measuring the size of custom-made clothing. Size measurers were mostly the shop master. And it was found that most clothing business firms had a problem when the measured size was applied to the pattern. Accordingly, it is necessary to provide education on size measurement for shop masters. 4. It was found that in the middle-aged women's clothing firms, the pattern correction of the length of sleeve, jacket and slacks occupied the highest percent. Accordingly, it is necessary to provide for the size system to complement the accurate somatotype characteristics of middle-aged women. 5. In custom-made clothing customer management, most firms engaged in customer somatotype management through size management. They provided customers with commodity information by informing them of the sales and event period and practiced human management for customers by maintaining the get-together and friendly relationship. 6. Middle-aged women's clothing businesses responded that it would be necessary to improve the fit of custom-made clothing and complement their pursuit for individuality as the plan to improve its quality. In consequence, it suggests that middle-aged women's clothing businesses should provide middle-aged women with the clothing of better-suited size and refined design. Middle-aged women's clothing businesses responded that it was the most urgent task to form the custom-made clothing manufacturing team as the plan to expand the custom-made clothing market, which is identified as their emphasis on the systematized production of custom-made clothing.