• Journal of Microbiology and Biotechnology
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• v.21 no.10
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• pp.1088-1096
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• 2011

The purpose of this study was to evaluate whether wild ginseng (WG) administration could attenuate anxiety- and depression-like behaviors and expression of corticotrophin-releasing factor (CRF) and neuropeptide Y (NPY) following withdrawal from repeated morphine administration in rats. Male rats were administered daily doses of WG (50, 100, or 200 mg/kg, i.p.) for 5 days, 30 min before morphine injection (40 mg/kg, s.c). The anxiety- and depression-like behavioral responses were measured 72 h after the last morphine injection using an elevated plus maze (EPM) and forced swimming test (FST), respectively. Changes in hypothalamic CRF and NPY expressions were also examined by analyzing their immunoreactivities in the hypothalamus. Daily administration of WG significantly reduced anxiety- and depression-like behavior, and elicited the suppression of CRF expression and the stimulation of NPY expression in the hypothalamus. Our results demonstrated that WG extract might be effective at inhibiting the anxiety and depression responses due to morphine withdrawal by possibly modulating the hypothalamus CRF and NPY systems. Furthermore, these findings imply that WG extract can be used for developing new medication to cure or alleviate morphine withdrawal symptoms and to prevent relapses of morphine use.

• Journal of Korea Entertainment Industry Association
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• v.14 no.4
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• pp.251-264
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• 2020

The purpose of this study was to examine the differences and the relationship between basic psychological needs and exercise addiction and to identify effects of To do this, the data were collected using the self-evaluating questionnaires on the exercise addiction, the of basic psychological needs, and the subjective were distributed to 305 participants in general exercise enthusiast for all, and the collected data. This study used the SPSS Statistics 18.0 program to process data. Exploratory factor analysis was performed for validity and Cronbach's α was performed for reliability. In addition, Frequency Analysis was carried out to analyze the demographic characteristics and Pearson's Correlation Analysis, independent t-test, one-way ANOVA, correlation analysis, multiple regression analysis Analysis were performed to verify the correlations and differences among variables. The significance level in this research was set at=.05 and the followings α are derived outcomes. The following is the comprehensive finding of the effect of general exercise enthusiast exercise addiction through basic psychological needs. First, there was no significant difference in basic psychological need and Exercise Addiction of general characteristics, but participation in 6 days was the highest in exercise amount per week. Second, Basic Psychological Need(autonomy, competition, relatedness) showed a high difference in Exercise Addiction(withdrawal symptoms, exercise need, emotional attachment). Third, correlation analysis between all variables showed statistically significant difference. Fourth, Basic Psychological Need(autonomy, competition) was found to have a high effect on Exercise Addiction(withdrawal symptoms, exercise need, emotional attachment).

• 대한예방의학회:학술대회논문집
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• 2002.10a
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• pp.555-555
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• 2002

• The Journal of Korean Medicine
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• v.35 no.4
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• pp.110-115
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• 2014

Objectives: A 54-year-old advanced gastric cancer patient developed severe fluid retention after docetaxel chemotherapy, at cumulative dose of $930mg/m^2$, with no improvement using diuretics or prophylactic glucocorticoids. Consequently, he changed chemotherapy regimen from docetaxel to paclitaxel. After he treated with herbal decoction Bangkihwangki-tang (BHT), which is widely used to treat several symptoms including edema in traditional Korean medicine, docetaxel-induced fluid retention (DIFR) was significantly improved along with associated symptoms, such as peripheral edema, pleural and pericardial effusion, pain, scleroderma, and hypoesthesia. As the symptoms were relieved, his performance status and ambulatory ability were improved. During herbal treatment, he continued chemotherapy without any problems and didn't show any adverse events related to herbal medicine. Although there is possibility of natural improvement progress after withdrawal of docetaxel, he showed shorter recovery period and significant improvement despite of severity of initial symptoms.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.4
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• pp.347-350
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• 2018

Drug-induced autoimmune hepatitis (DIAIH) is an increasingly recognized form of drug-induced liver injury that leads to a condition similar to idiopathic autoimmune hepatitis. A number of drugs have been associated with DIAIH, minocycline is one of the most well characterized. Minocycline is a semisynthetic tetracycline antibiotic used in the treatment of acne vulgaris. Minocycline-induced autoimmune hepatitis presents with serologic and histologic features similar to idiopathic autoimmune hepatitis. However, the natural history and outcomes of these two conditions differ significantly. The majority of patients with minocycline-induced autoimmune hepatitis experience complete resolution of symptoms after withdrawal of the medication. Some patients may require a short course of steroids and rarely use of an immunomodulator to achieve resolution of disease. Recurrence of symptoms is rare and typically only occurs with reintroduction of minocycline. It is important for primary care providers to consider minocycline-induced autoimmune hepatitis when liver injury develops during minocycline therapy.

• Journal of Yeungnam Medical Science
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• v.10 no.2
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• pp.544-549
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• 1993

The authors have experienced a case of organic mental disorder with bilateral frontal lobe atrophy in a 36-year-old man. He showed negative symptoms of schizophrenia such as anhedonia, social withdrawal, flat affect, poverty of thought.

• Korean Journal of Child Studies
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• v.26 no.1
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• pp.123-135
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• 2005

This study examined conditions and influential factors of psycho-behavioral adjustment in abused children who had been returned home after out-of-home care. Subjects were selected nationwide from the Center for the Prevention of Child Abuse. Subjects were 54 cooperative children selected from among 126 returned children : they were older than 11 years of age and had experienced more than one day in out-of-home care between January 2002 and December 2003. Findings were: (1)children had such psychological adjustment symptoms as withdrawal, depression, or anxiety, rather than symptoms of misdeeds and aggression. (2) Level of self-esteem and re-abuse were the great influential factors in psycho-behavioral adjustment. This result shows that the processes of out-of-home care and returning home remain important issues for abused children.

• Journal of Society of Preventive Korean Medicine
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• v.22 no.2
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• pp.125-132
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• 2018

Objectives : This survey assessed Korean medical doctors' (KMDs') use and perception of smoking cessation therapies in traditional Korean medicine (TKM) and their drawbacks. Methods : A total of 14,485 KMDs affiliated with the Association of Korean Medicine were sent surveys via email. They were asked the use and perception of smoking cessation therapies in TKM and their drawbacks: Present use of Korean medicine treatment for smoking cessation, ideal treatment for smoking withdrawal symptoms, advantages and disadvantages of smoking cessation treatments in Korean medicine were asked with closed-ended questionnaire. Results : Two hundred fifty-three KMDs (1.75%) responded to the questionnaire. According to the results of the study, more than half of KMDs (51.4%) answered that they have practiced smoking cessation therapy. The most frequently used treatments for smoking cessation were ear acupuncture (EA) (74.6%) and acupuncture (15.4%), and the most of TKM doctors said that they were the most effective treatments. The advantages of smoking cessation treatment in TKM were the fewer adverse events (53.4%), availability to stimulate acupoints continuously in everyday life (48.2%), and the possibility of controlling withdrawal symptoms. Disadvantages included the long treatment duration and the necessity of frequent visits to the doctor. The greatest disadvantage was the lack of sufficient evidence for the effectiveness of TKM smoking cessation protocols. Conclusions : Despite of the low response rate, the survey results show that the main treatment modalities for smoking cessation are acupuncture, and this was also estimated effective for stop smoking. However, to improve smoking cessation rate, the more various smoking cessation treatments should be developed.

• Journal of the Korea Society of Computer and Information
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• v.15 no.6
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• pp.129-138
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• 2010

The purpose of this study was to analyze the difference between Exercise addiction and Affect, and addiction-related potential was investigated. In addition, exercise addiction prevention and positive exercise was to identify. The participants of the study included 312 tennis club member who were more than 20 years old and lived in seoul city. The survey was analyzed by SPSS PC+ for window (version 12.0) which is a statistical analysis program to produce the computational results of this study. Based on the survey, this study could draw such results as follows: First, exercise addiction, gender and age on partial variables were statistically significant differences. A male positive addictions, exercise desire were higher than in female. 50s in the withdrawal symptoms of the variables that showed statistically significant difference participation, and period, frequency, time of exercise addiction showed that in withdrawal symptoms, positive addictions domain in a statistically meaningful differences. Second, social demographic domain in the presence of gender showed significant correlation exercise desire were and exercise participation time in the positive addictions showed significant correlation. Participation frequency and the time involved in retaining all the positive affect and negative affect have found a high correlation. Third, the influence of relation between exercise addiction and affect of tennis participants, exercise desire, positive addiction, showed in a statistically positive affect and negative affect meaningful influence on it.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.4
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• pp.231-245
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• 2017

The purpose of this study is to analyze the trend line through scatter diagram analysis on correlation between SNS addiction tendencies and learning attitudes, figure out the knee point influencing learning attitudes negatively in detail, and examine influence among subareas. To address the goal, study questions are formulated as follows. First, this author did screening on the data of variables measured and analyzed descriptive statistics. Second, this researcher produced the trend line by drawing a scatter diagram in order to analyze correlation between SNS addiction tendencies, withdrawal symptoms, excessive communication, and excessive time wasting, and learning attitudes exploratorily. Third, to explore correlation between self-evaluation, learning participation, and developmental attitudes, the subfactors of learning attitudes related to SNS addiction tendencies, this author drew a scatter diagram and analyzed the threshold of positive and negative correlation. To verify the study questions, the SNS addiction tendency scale and learning attitude scale were applied to 301 university students in Chungcheong area. According to the study results, first, their learning attitudes are influenced by SNS addiction tendencies, excessive communication and excessive time wasting, and they are not influenced by withdrawal symptoms that much. Second, excessive communication, a factor of SNS addiction tendencies, and self-evaluation and developmental attitudes, factors of learning attitudes, show positive correlation to some extent and indicate negative correlation after the threshold. However, excessive communication and learning participation are found to show no correlation. Third, according to the results of examining correlation with learning attitudes by dividing them into excessive communication and excessive time wasting groups with the knee point of 1.40, as the symptom of excessive communication is found more, it influences self-evaluation, learning participation, developmental attitudes, and learning attitudes more negatively in general. The result of this study is expected to provide foundational material necessary to develop educational programs to prevent undergraduates' excessive SNS use and SNS addiction which can be used in the scenes of counseling or education.