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Preparation of Functional Cosmetics Containing $\beta$-carotene Derived from Recombinant Escherichia coli and Evaluation of Anti-wrinkle Efficacy by Clinical Testing (재조합 대장균 유래 베타카로틴이 함유된 기능성 화장품 제조 및 이의 임상실험을 통한 주름개선 효능 평가)

  • Kim, You-Geun;Lee, Young-Hoon;Kang, Moon-Kook;Lee, Byung-Hak;Yun, Jun-Ki;Kim, Sung-Bae;Kim, Chang-Joon
    • Microbiology and Biotechnology Letters
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    • v.37 no.4
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    • pp.399-404
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    • 2009
  • This paper described the formulation of functional cosmetics and evaluation of anti-wrinkle efficacy in clinical test. Cosmetics were formulated with highly purified $\beta$-carotene obtained from the culture broth of recombinant E.coli cells. Edible oil for solubilizing $\beta$-carotene, vitamine E for long-term storage, detergent/stabilizer (2.0%) for the complete formation of oil/water emulsion, dimethicone (0.35%) for good skin care, and sorbitol for skin moisturizer were also added as ingredients. Physical or chemical degradation of formulated products stored at $0^{\circ}C$, $25^{\circ}C$, or $40^{\circ}C$ was not observed for 60-day testing period. In clinical test, 68% of applicants observed wrinkle decrease after 8-week treatment. This result indicates that newly formulated cosmetics have strong potential for improving wrinkle skin care.

The Technological Competitiveness Analysis of Energy Harvesting by Using the Patents Information (특허정보를 활용한 에너지 하베스팅 기술의 기술경쟁력분석: 한국, 미국, 일본, 유럽, 중국을 중심으로)

  • Kim, Dae-Gi;Lee, Pill-Woo;Kim, Jae-Sung
    • Journal of Korea Technology Innovation Society
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    • v.17 no.1
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    • pp.25-44
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    • 2014
  • This study analyzed technological competitiveness of five major countries by using patent information that is typical intellectual property. Technological activity, patent competitiveness, market securement and patent concentration were designed as evaluation items for the technological competitiveness analysis, and the number of patent applications, family patents and triad patent families, and the paten concentration index were reflected as evaluation factors to be scored. For technologies to be analyzed, it referred to the energy harvesting technologies selected as 500 future technologies in the future technologic white paper 2013 published by KISTI. They were classified into technologies using thermoelectric, piezoelectric and photovoltaic elements, which are main detailed technologies of the energy harvesting technology, to investigate and analyze patent information for each detailed technology to understand their technological competitiveness. As a result, the United States ranked top with 75 and 70 points in the technology using thermoelectric and piezoelectric elements respectively, and Japan ranked top with 90 points in the energy harvesting technology using photovoltaic elements. It was analyzed that Korea held the second rank in the field using piezoelectric and photovoltaic elements, and the fifth in the technology using thermoelectric elements.

Lessons from the Policy Implications of Green Logistics in Europe (유럽녹색물류의 정책적 시사점과 교훈)

  • Kim, Jin-Hwan
    • Journal of Distribution Science
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    • v.12 no.2
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    • pp.27-37
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    • 2014
  • Purpose - As economic activities between different countries have rapidly spread in a world of free trade, it is inevitable that a large volume of cargo will be carried between countries. It is natural, then, that CO2 emissions and other environmental pollutions have followed, which exposes people and society to serious environmental problems and social costs, and so on. Therefore, the need to understand logistics is not only a matter of transportation but also an environmentally oriented matter. The purpose of this study is to look at some lessons and implications from the European case in terms of green logistics matters. Research design, data, and methodology - In order to look into this matter, first, it has to be established that some cargo transport volumes using different transportation modes have clearly declined because of previous economic recessions. Some transport policies produced by the European Union (EU) are based in a long history of struggling to cope with transport matters in European countries. In its recent transport policies, the EU has provided greener transportation alternatives, realizing that pollution matters affect the European transport market. This study tries to determine what policies the EU has implemented to deal with green logistics matters. This study concentrates in particular on the Marco Polo program in the EU. Results - This study found that the EU seems to consider these kinds of matters, that is, transport and the environment in the context of green logistics. The EU launched some policy instruments to solve this matter relatively earlier than other countries and reviewed them as necessary. In order to make these policy tools work, the EU provided PACT for combined transport, and then the Marco Polo I and II European transport white paper packages. These European policies deal with green logistics matters in two ways. First, some restrictions have been imposed, especially taxation, and so on. Transport subsidies are also powerful means of handling green logistics matters in Europe. Along with these two means of dealing with transport and the environment, the EU eventually targeted integration of different transport modes. Instead of employing only a single transport instrument mode to deliver the cargo to be carried, such as trucking, rail, ocean-going carrier, flight, or inland waterway transport, the EU has proposed that combining transport modes is the best alternative for transport and the environment. That is, the EU is pursuing the adoption of multimodalism as an answer to the green logistics challenge as it provides a more cost efficient and more productive means of transport. Conclusions - In conclusion, multimodal transport should be considered when applying green logistics, as it can provide an alternative way to achieve transport and environmental solutions together at the present time. Two methods can be used to encourage multimodal transport: restrictions and subsidies. These are the lessons and implications from European green logistics policies.

Changes of Histamine Contents in the Muscle of Dark-Fleshed Fishes during Storage and Processing Changes of Histamine Contents in the Muscle of Mackerel Pike (적색육어류의 저장 및 가공중의 histamine 함량의 변화 一꽁치에 있어서의 변화-)

  • PARK Yeung-Ho;KIM Seun-Bong;JEONG Hae-Kyung;KOH Kwang-Bae;KIM Dong-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.14 no.3
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    • pp.122-129
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    • 1981
  • Histamine has been known to be one of the causative materials of allergy-like food poisoning from eating of the meat of the dark-fleshed fishes. In the previous study, we had reported the changes of histamine contents fin three kinds of the dark-fleshed fishes. The present paper was also conducted to investigate the changes of the histamine contents in the mackerel pike, and compare with the white-fleshed fish, spanish mackerel, under different condition of storage and processing. The formation of histamine in the muscle of mackerel pike was markedly higher than spanish mackerel. Referring to temperature, the formation of histamine at $12^{\circ}C$ was observed more rapid than that at $2^{\circ}C$. In the muscle of mackerel pike, the histamine contents reached the levels of 98.3mg/100g for at the storage for 5 days at $12^{\circ}C$. But in that of spanish mackerel, the content showed the level of 4.9mg/100g at the storage 7 days at $12^{\circ}C$. The histamine contents in sun dried products of the samples were higher than those of rat-materials, salted or hot-air dried products.

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Hand Gesture Recognition Algorithm Robust to Complex Image (복잡한 영상에 강인한 손동작 인식 방법)

  • Park, Sang-Yun;Lee, Eung-Joo
    • Journal of Korea Multimedia Society
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    • v.13 no.7
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    • pp.1000-1015
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    • 2010
  • In this paper, we propose a novel algorithm for hand gesture recognition. The hand detection method is based on human skin color, and we use the boundary energy information to locate the hand region accurately, then the moment method will be employed to locate the hand palm center. Hand gesture recognition can be separated into 2 step: firstly, the hand posture recognition: we employ the parallel NNs to deal with problem of hand posture recognition, pattern of a hand posture can be extracted by utilize the fitting ellipses method, which separates the detected hand region by 12 ellipses and calculates the white pixels rate in ellipse line. the pattern will be input to the NNs with 12 input nodes, the NNs contains 4 output nodes, each output node out a value within 0~1, the posture is then represented by composed of the 4 output codes. Secondly, the hand gesture tracking and recognition: we employed the Kalman filter to predict the position information of gesture to create the position sequence, distance relationship between positions will be used to confirm the gesture. The simulation have been performed on Windows XP to evaluate the efficiency of the algorithm, for recognizing the hand posture, we used 300 training images to train the recognizing machine and used 200 images to test the machine, the correct number is up to 194. And for testing the hand tracking recognition part, we make 1200 times gesture (each gesture 400 times), the total correct number is 1002 times. These results shows that the proposed gesture recognition algorithm can achieve an endurable job for detecting the hand and its' gesture.

Q Analyses of the Structure of Internet Bookstore Users' Subjectivity (인터넷 서점 이용자의 주관성에 관한 Q분석)

  • Jung Huyn-Wook;Kang Hye-Young;Kim Sun-nam
    • Journal of Korean Library and Information Science Society
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    • v.36 no.2
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    • pp.197-220
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    • 2005
  • This paper examined the structure of internet bookstore users' subjectivity by focusing on their beliefs, values and attitudes.0 methodology was utilized for the study. After constituting 36 Q sample and 28 P sample, data were collect from April 15, 2005 to April 22 2005. The analyses showed 3 types of subjectivity structures. The first one was 'the economic benefit-seeking type.' Those in this type were motivated to use internet bookstores to achieve economic benefits. They paid more attention to the Prices discounted than the web site contents provided by internet bookstores. This type was conspicuously found among college students. The second one was the 'information-seeking type.' People in this category made visits to internet bookstores in order to obtain new information or professional materials. This type was dominantly found among women. The third one was the 'convenience-seeking type.' Those in this type were concerned not only with the accessibility and convenience, but also with such practical issues as delivery, price, applicability, payment, and bonus. This type was conspicuously observed among white collar workers. These findings suggests that in order to make internet bookstores more attractive to users, it is demanded to understand various needs held by users and map out sophisticated marketing strategies on the basis of such a knowledge.

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HISTOLOGIC CHANGE OF THE POSTERIOR ATTACHMENT IN ANTERIOR DISC DISPLACEMENT OF THE TEMPOROMANDIBULAR JOINT-A NEW MODEL OF INTERNAL DERANGEMENT IN RABBITS (실험가토의 악관절원판 변위시 후방부착조직의 변화)

  • Kim, Tae-Woo;Ko, Jea-Seung;Chang, Young-il
    • The korean journal of orthodontics
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    • v.23 no.4 s.43
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    • pp.503-527
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    • 1993
  • This paper describes a new method to create an animal model for TMJ internal derangement in the New Zealand white rabbits and the light and electron microscopical changes of posterior attachment of them. Twenty six rabbits(2.5-3.0kg), four normal and twenty two experimental, were used. The right disc of experimental animal was displaced anteriorly without sectioning the posterior attachment and tied to the zygomatic arch with nylon not to be reduced to the original position. The left TMJ was sham-operated to be compared with its right experimental one. Normal animals were sacrificed one day and eight weeks after experiment. Experimental animals were sacrificed one day, ten days, three weeks, five weeks and eight weeks after surgery respectively. They were fixed intravenously with $2\%$ glutaldehyde under general anesthesia and the samples of them were processed for light and electron microscopic examination. The purpose of this experiment is to make a suitable animal model of disc displacement without reduction for studying and understanding the cellular and morphologic events in posterior attachment of TMJ including early changes which were difficult to be observed in human TMJs. The results of this investigation suggest the following conclusions : 1. Authors induced anterior disc displacement surgically in rabbits with new method to examine histologic changes of posterior attachment. Tissue reactions of this model seem to be similar to those observed in human disc displacement. We think this animal model for anterior disc displacement may be used to explore and evaluate objectively the effects of many treatment modalities in disc displacements. 2. The animal disease model showed inflammation at early stage(one and ten days). At this stage there were mild-to-severe mononuclear inflammatory cell infiltration, numerous newly formed vessels, vessel dilatation and engormement and many fibroblasts. 3. At middle stage(three weeks), fibrosis occurred, where fibroblasts decreased in number, but their cytoplasm was profuse indicating high activity. Collagen fibers increased in number and the tissue looked more dense. 4. At late stage(five weeks and eight weeks) showed degenerative changes including perforation of posterior attachment, disintegration of collagen fiber bundles, degeneration of fibroblasts, metastatic ossification, and dystrophic calcification.

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Worsening Tension Between the United States and China in the South China Sea, A Sign of 'Thucydides Trap'? (미(美) Lassen 함(艦)의 남중국해(南中國海) 기동(機動)은 '투키디데스 함정'의 전조(前兆)?)

  • Yang, Jeong-Sung
    • Strategy21
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    • s.38
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    • pp.287-320
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    • 2015
  • On October 27, 2015, USS Lassen(DDG82), a 9,200 ton class Aegis destroyer of the United States Navy, began its operations within 12 nautical miles of Subi Reef, one of the seven artificial islands that China has built and claimed sovereignty over. The maneuver was joined by anti-submarine patrol airplanes such as P-8A and P-3. The White House press secretary mentioned that the President of the United States approved the operation. In response, China announced that it warned the US Navy ship about the 'illegal violation' by sending two destroyers(PLAN Lanzhou and Taizhou). This event represents a close call case where tension between the United States and China in the South China Sea might have been elevated to a conflict between the two navies. Moreover, considering that this happened only one month after Chinese president Xi's state visit to the United States, the event shows that the positions of the two countries have become starkly different to the extent that they are so hard to be reconciled. The United States' position is different from those of Vietnam and the Philippines. Countries like Vietnam and the Philippines have been directly involved in disputes with regard to sovereignty claims across the waters in the South China sea. As for the United States, being a third party in the disputes, it still cannot be a by-stander watching the whole waters in the region fall under the influence of China. Accordingly, the United States maintains that all countries bear the rights of innocent passage and military operations in the Exclusive Economic Zones(EEZ) as stipulated by the United Nations Convention on the Law of the Sea(UNCLOS). In contrast, China claims that, historically, the South China sea has been part of China's territorial waters, and that foreign countries are not allowed to conduct military operations within the waters. It strongly accuses that such military operations are illegal. Against this background, this paper tracks the different positions of the United States and China on the issues regarding the South China sea. It also carefully looks at the possibility that, in the process of dealing with the issues, the two countries may get into an armed conflict as the phrase 'Thucydides Trap' predicts.

Performance of IEEE 802.11b WLAN Standard at In-Vehicle Environment for Intelligent U-Car System (지능형 U-Car에서 IEEE 802.11b을 이용한 차량 내 데이터 무선 랜 전송 성능 분석)

  • Lee Seung-Hwan;Heo Soo-Jung;Park Yong-Wan;Lee Sang-Shin;Lee Dong-Hahk;Yu Jae-Hwang
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.43 no.9 s.351
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    • pp.80-87
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    • 2006
  • In this paper, we analyze the performance of IEEE 802.11b WLAN communication between access point(AP) and mobile equipment(ME) in 2.4 GHz band with noise and interference factors. WLAN communication at in-vehicle environment is assumed as the communication between main vehicle controller and electronic device such as sensor, ECU (Electrical Control Unit) in vehicle on telematics field for implementing wireless vehicle control system. Received interference level from other system's mobile equipment in the same band and automobile noise from each part of vehicle can be the main factors that can cause increasing error rate of control signal. With these (actors, we focus on the Eb/No the BER performance of WLAN for analyzing the characteristic of interference factors by the measured bit error rate.

Evaluation of Thermal Insulation Properties of Covering Materials to Protect Peach Trunks against Freezing Injury (복숭아 주간부 동해 예방을 위한 피복재의 보온성 평가)

  • Shin, Hyunsuk;Yun, Seok Kyu;Choi, In Myung;Kim, Sung Jong;Yun, Ik Koo;Nam, Eun Young;Kwon, Jung Hyun
    • Journal of Bio-Environment Control
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    • v.25 no.4
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    • pp.288-293
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    • 2016
  • The study was performed to evaluate thermal insulation covering materials (TICMs) to protect peach trunks against freezing temperatures in winter season by investigating thermo-physical properties and practical thermal insulation effect of the TICMs which was made of white non-woven fabrics, yellow paper sheets, and waterproof fabric pads. Among the three TICMs, Waterproof fabric pad (double layer) possessed the best performance about thermal insulation rate and thermal resistance among three kinds of TICMs. Day thermal insulation effects of waterproof fabric pad, which prevent from temperature rise on the bark tissues of trunks during the day time, were $14.09^{\circ}C$. Night thermal insulation effects of them, which prevent from temperature decline on the bark tissues of trunks at night time, were $7.23^{\circ}C$. Waterproof fabric pad showed the highest day and night thermal insulation effects. Thus our results suggest that development of TICMs using waterproof fabric pad might be helpful to protect the bark tissues of trunks from freezing injury.