• Tuberculosis and Respiratory Diseases
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• v.76 no.6
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• pp.261-268
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• 2014

Patients with immune-mediated inflammatory diseases (IMIDs) are increasingly being treated with anti-tumor necrosis factor (TNF) agents and are at increased risk of developing tuberculosis (TB). Therefore, diagnosis and treatment of latent TB infection (LTBI) is recommended in these patients due to the initiation of anti-TNF therapy. Traditionally, LTBI has been diagnosed on the basis of clinical factors and a tuberculin skin test. Recently, interferon-gamma releasing assays (IGRAs) that can detect TB infection have become available. Considering the high-risk of developing TB in patients on anti-TNF therapy, the use of both a tuberculin skin test and an IGRA should be considered to detect and treat LTBI in patients with IMIDs. The traditional LTBI treatment regimen consisted of isoniazid monotherapy for 9 months. However, shorter regimens such as 4 months of rifampicin or 3 months of isoniazid/rifampicin are increasingly being used to improve treatment completion rates. In this review, the screening methods for diagnosing latent and active TB before anti-TNF therapy in patients with IMIDs will be briefly described, as well as the current LTBI treatment regimens, the recommendations for managing TB that develops during anti-TNF therapy, the necessity of regular monitoring to detect new TB infection, and the re-initiation of anti-TNF therapy in patients who develop TB.

• Architectural research
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• v.20 no.3
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• pp.93-102
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• 2018

With the change in Earth's ecosystems due to climate change, a number of studies on zero energy buildings have been conducted globally, due to the depletion of energy and resources. However, most studies have concentrated on residential and office buildings and the performance predictions were made only in the design phase. This study verifies the zero-energy performance in the operational phase by acquiring and analyzing data after the completion of an exhibition building. This building was a retention building, in which a renewable energy system using a passive house building envelope, solar photovoltaic power generation panels, as well as fuel cells were adopted to minimize the maintenance cost for future energy-zero operations. In addition, the energy performance of the building was predicted through prior simulations, and this was compared with actual measured values to evaluate the energy performance of the actual operational records quantitatively. The energy independence rate during the measurement period of the target building was 123% and the carbon reduction due to the energy production on the site was 408.07 tons. The carbon reduction exceeded the carbon emission (331.5 tons), which verified the carbon zero and zero-energy performances.

• Journal of the Korean Ceramic Society
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• v.46 no.2
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• pp.181-188
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• 2009

The electrical property and microstructure in $BaTiO_3$ ceramics doped rare-earth ions with intermediate ionic size ($Dy^{3+},Ho^{3+},Y^{3+}$) were investigated. Microstructures have been characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). Incorporation of rare-earth ions to $BaTiO_3$ ceramics depended on their ionic radius sensitively. Compared to Ho and Y ions, Dy ions provide $BaTiO_3$ ceramics with the high rate of densification and well-developed shell formation, due to their high solubility in the $BaTiO_3$ lattice, but the microstructure of Dy doped $BaTiO_3$ ceramics is unstable at high temperature, because Dy ions could not play a role of grain growth inhibition, leading to diffuse into $BaTiO_3$ lattice continuously after completion of densification during sintering. Comparing electrical property and microstructure, it is shown that the reliability of capacitor improved by high shell ratio.

• YAKHAK HOEJI
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• v.47 no.3
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• pp.135-141
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• 2003

The majority of table salts are bay salts and chemical salts. However, chemical salts are known to have a different composition in biological electrolytes and quality of bay salts are getting worse due to the increasing seawater contamination. These facts may have led to the increasing usage of various health-promoting salts. Bamboo salt was introduced in 1986 as a solution to replace table salts to eliminate those detrimental effects, to promote general health and to treat diseases. Although all bamboo salts from different manufacturers have been used for the same health and medical purposes, each manufacturer utilizes different manufacturing process. The ICP analysis was used to study the changes of elemental contents in a bamboo salt during the manufacturing steps as well as these contents in various bamboo salts and other salts. After the first step, contents of Li and Sr in the bamboo salt were increased in comparison with those in the raw material, bay salt. As the next steps continued, contents of K, Ca and Ba were continuously increased. At the completion of the final step, contents of Mg and P were decreased and those of Cu, Mn and Mo were gradually increased. Bamboo salts contained lower contents of Mg, Al, B, and P, but higher contents of K, Ca, Fe, Cu, Mn, Zn, Li, Ba, Sr and Mo than bay salt.

• Clinical and Experimental Pediatrics
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• v.53 no.3
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• pp.273-285
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• 2010

Completion of the human genome project has allowed a deeper understanding of molecular pathophysiology and has provided invaluable genomic information for the diagnosis of genetic disorders. Advent of new technologies has lead to an explosion in genetic testing. However, this overwhelming stream of genetic information often misleads physicians and patients into a misguided faith in the power of genetic testing. Moreover, genetic testing raises a number of ethical, legal, and social issues. Diagnostic genetic tests can be divided into three primary but overlapping categories: cytogenetic studies (including routine karyotyping, high-resolution karyotyping, and fluorescent in situ hybridization studies), biochemical tests, and DNA-based diagnostic tests. DNA-based testing has grown rapidly over the past decade and includes preandpostnatal testing for the diagnosis of genetic diseases, testing for carriers of genetic diseases, genetic testing for susceptibility to common non-genetic diseases, and screening for common genetic diseases in a particular population. Theoretically, once a gene's structure, function, and association with a disease are well established, the clinical application of genetic testing should be feasible. However, for routine applications in a clinical setting, such tests must satisfy a number of criteria. These criteria include an acceptable degree of clinical and analytical validity, support of a quality assurance program, possibility of modifying the course of the diagnosed disease with treatment, inclusion of pre-and postnatal genetic counseling, and determination of whether the proposed test satisfies cost-benefit criteria and should replace or complement traditional tests. In the near future, the application of genetic testing to common diseases is expected to expand and will likely be extended to include individual pharmacogenetic assessments.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.37
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• pp.253-273
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• 2008

The thesis examines the problems for improvement of clearance procedure and shows the various ways of overcoming them. Practical implications regarding the innovation of clearance procedure are as follows. First, the basis of information for customs clearance service should be built for unifying customs clearance information and imports and exports goods. Second, Customs Service need to keep on trying continuously that customs clearance system should be inter-convertible in the inside and outside of the country. Third, reliable law and execution system should be needed to revitalize customs clearance business and the government need to take measures for new system which is suitable for our own country. Finally, mutual cooperation administration system for customer in domestic and foreign country should be made for supplying high quality clearance service. As we have reviewed above contents, the customs clearance business meet the needs of innovation with new information technique to overcome lots of problems which come by when we execute simplification of customs clearance procedure and customs inspection administration fairly. As well as, when we review a few methods in the line of our customs system, we need strongly completion of related system and arrangements in trade business and similar fields. Hereafter we hope the limitation of this study should be overcome by the process of proper inspections through subsequent studies.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.1382-1387
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• 2004

From the viewpoint of a macro state, there is no thermal boundary resistance (TBR) at an interface if both surfaces at an interface are perfectly contacted. However, recent molecular dynamics (MD) studies reported that there still exists the TDR at the interface in an ideal epitaxial superlttice. Our previous studies suggested the model to predict the TBR not only quantitatively also qualitatively in superlattices. The suggested model was based on the classical theory of a wave reflection, and provided highly satisfactory results for an engineering purpose. However, it was not the complete model because our previous model was derived by considering only the effects from a mass ratio and a potential ratio of two species. The interaction of two species presented by the Lennard-Jones (L-J) potential is governed by the mutual ratio of the masses, the potential well depths, and the diameters. In this study, we performed the preliminary simulations to investigate the effect resulting from the diameter ratio of two species for the completion of our model and confirmed that it was also a ruling factor to the TBR at an interface in superlattices.

• Asia-Pacific Journal of Business
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• v.6 no.1
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• pp.59-82
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• 2015

According to the survey on the state of practical usage and present situation of FTAs, conducted among trade companies operating in Shandong province in 2014, more than 90% of companies are believed to be small and medium sized enterprises. Therefore this study tries to test what impact the awareness and utilization of an FTA have on its outcome among trade companies operating in Shandong province as well as partner countries and other trade companies. The research results are as follows. First, we found a positive correlation between 1) a company's global orientation (as measured in export density as a percentage of profit) and 2) its competitiveness (as measured in annual sales), and a company's degree of utilization of FTA provisions. Second, One of the findings is that the more aware of the (exporting) HS code, conventional tariffs and the process of issuing C/O the companies from Shandong province are the more they actually use (utilize) an FTA inpractice. Another interesting finding is that the more aware of the (exporting) HS code and conventional tariffs the enterprises are the higher is their practical usage level of an FTA. Third, however, at the time of this study's completion, FTA utilization was not yet positively correlated with statistically significant performance results. Therefore, to increase the utilization and performance of FTA, the China government have to make a efficient business models for each industry and support the small and mid-size businesses including Shandong province's SMEs.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.2
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• pp.153-163
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• 2011

Energy efficiency and indoor air quality have become main issue to develop healthy and sustainable building in these days. As an effort to reduce the energy consumption in multi-residential building, many attempts as like passive design strategies and renewable energy as well as active control method are tried. However, underground parking lot in multi-residential building seldom adopt the sustainable strategies and only mechanical system is installed as usual. Moreover, the mechanical system installed in underground parking lot is rarely operated due to the electric demand for operation after completion. In this study, as an energy efficient measure, natural ventilation system using stack effect as a driving force for underground parking lot will be proposed and the performance of the suggested system will be analyzed by simulation method.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.16 no.1
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• pp.22-30
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• 2009

Purpose: This study examined caregiver trainees' knowledge and attitude toward the elderly. Method: This descriptive study was conducted with a convenient sample of 119 trainees in a long-term caregiver education program at one university. Following completion of a self-reported questionnaire, knowledge and attitude were measured using FAQ1(Palmore, 1998) and a 20-item semantic differential scale(Sanders et al., 1984). The data were analyzed using descriptive analysis, t-test, ANOVA, and Pearson correlation analysis by SPSS version 12.0. Results: The mean score of respondents' knowledge and attitude toward the elderly was $13.51{\pm}2.77$ out of 25 and $81.71{\pm}20.10$ out of 100, respectively. Caregiver trainees' education level and age influenced their knowledge and attitude, respectively, toward the elderly. Conclusion: Caregiver training for the elderly should involve a well-designed education program and continuous teaching that takes into account trainee education and age.