• Korean Journal of Social Welfare Studies
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• v.42 no.3
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• pp.355-379
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• 2011

The purpose of this study is to reveal the similarity and difference by comparing the quality of life between senior citizen group and disabled people group. For this purpose, I surveyed the questionnaire composed of sociological variable of population, social support, society activity participation, activity of daily living, self-efficacy, and quality of life to 113 senior citizens and 107 disabled people and analyzed the actual proof relationship of cause and effect in between variables. I executed the analysis of structural equation model by using SPSS 14.0 and AMOS 7.0 for the analysis of data. As the result of the study, firstly, the variables highly co-related with the quality of life to both senior citizen group and disabled people group were self-efficacy and society activity participation, and the variables highly co-related with self-efficacy were the quality of life and society activity participation. Secondly, the variables which show the meaningful difference between senior citizen group and disabled people group were society activity participation and activity of daily living. Thirdly, in the senior citizen group, social support, society activity participation, and activity of daily living have meaningful effect on self-efficacy, and all variables have meaningful effect on the quality of life. However, in the disabled people group, social support did not have meaningful effect on self-efficacy, and the social support and self-efficacy did not have meaningful effect on the quality of life. Based upon these study results I discussed the meaning and implications of the study, and suggested the successive study tasks.

• Journal of the Korea Society of Computer and Information
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• v.28 no.10
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• pp.247-256
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• 2023

This study was conducted with the purpose of suggesting alternatives for the efficient operation of senior day care facilities in 22 cities and counties in the Jeonnam region by analyzing the efficiency of senior day care facilities. The analysis data for the study used the National Health Insurance Corporation's long-term care insurance for the elderly (2022), the Input variables were the number of facilities, the number of workers, the number of affordable, and the number of senior long-term care insurance recipients and the Output variables were the the number of users. As a result of the analysis, CCR was most efficient in Goheung-gun, Gokseong-gun, Gwangyang-si, Boseong-gun, Yeongam-gun, and Jindo-gun, BCC was most efficient in Goheung-gun, Gokseong-gun, Gwangyang-si, Gurye-gun, Damyang-gun, Boseong-gun, and Jindo-gun, and SE was most efficient in that order: Jindo-gun, Gokseong-gun, and Gwangyang-si. It turned out to be a super efficient area. In the contribution analysis, the number of affordable and workers variables were found to be variables that had a large impact on efficiency contribution. In the improvement potential analysis, the number of facilities variable was found to be a variable that had a significant impact on efficiency. Therefore, for the efficient operation of senior day care facilities, we suggest adjusting supply and demand, such as the number of facilities and affordable, and suggest that training programs to strengthen the expertise of workers who contribute greatly are required.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.386-394
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• 2016

This study investigates the validity of a Korean version of the Client Assessment Summary (CAS), which is a tool used to assess the recovery of alcoholics. We investigated the Korean CAS's suitability for use in assessing the scale of recovery scale of general alcoholics in Korea. In this study, we analyzed the data of 205 abstaining alcoholics in order to determine the validity of the Korean CAS. We undertook relationship analyses of CAS contents, reliability, and composition validity through factor analysis. In addition, we assessed ARS, abstinence period, abstinence self-efficacy, illness insight, and motivation change variables. The factor analysis results, performed after verification of content suitability by assessing 12 questions and 4 factors, confirmed the tool's composition validity, with the results showing relatively high values (R2 = 76.26%, communality ${\geq}0.6$, and KMO = 0.92). Moreover, internal consistency was acceptable (Cronbach's alpha = 0.92), and the correlations among ARS, abstinence self-efficacy, illness insight, and motivation change variables confirmed the validity of the Korean CAS. The proposed Korean CAS is expected to be useful when academically and clinically assessing the recovery of alcoholics; thereby, eventually contributing to successful recoveries from alcoholism.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.627-634
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• 2017

The purpose of this study was to investigate the effects of elementary school students' stress and social support on smartphone addiction and school adjustment. Our hypothesis is that stress and social support of elementary school students affects smartphone addiction and school adjustment. In addition, the study model assumes that stress and social support of elementary school students were mediated by the effects of smartphone addiction. Analysis results found that elementary school students' stress affects smartphone addiction and school life adaptation, and social support influences school life adaptation. Elementary students' smartphone addiction has little influence on school life adjustment. Stress in elementary school students has a strong influence on smartphone addiction, social support, and adaptation to school life. In other words, higher stress levels results in higher frequency of use of smartphones, which may directly affect smartphone addiction and the ability to adapt to school life. The effects of stress and social support of elementary school students on school life adaptation and smartphone addiction were ultimately indirect. Based on the research results, this study suggests policy implications for elementary school students' addiction to smartphone and ability to adapt to school life.

• International Journal of Oral Biology
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• v.45 no.3
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• pp.99-106
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• 2020

Ficus carica L. (fig) is one of the first cultivated crops and is as old as humans. This plant has been extensively used as a traditional medicine for treating diseases, such as cough, indigestion, nutritional anemia, and tuberculosis. However, the physiological activity of fig leaves on oral cancer is as yet unknown. In this study, we investigated the anticancer effect of methanol extracts of Ficus carica (MeFC) and the mechanism of cell death in human FaDu hypopharyngeal squamous carcinoma cells. MeFC decreased the viability of oral cancer (FaDu) cells but did not affect the viability of normal (L929) cells, as determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay and Live and Dead assay. In addition, MeFC induced apoptosis through the proteolytic cleavage of procaspase-3, -9, poly (ADP-ribose) polymerase (PARP), downregulation of Bcl-2, and upregulation of Bax, as determined by 4′,6-diamidino-2-phenylindole dihydrochloride staining and western blot analysis. Moreover, a concentration of MeFC without cytotoxicity (0.25 mg/mL) significantly suppressed colony formation, a hallmark of cancer development, and completely inhibited the colony formation at 1 mg/mL. Collectively, these results suggest that MeFC exhibits a potent anticancer effect by suppressing the growth of oral cancer cells and colony formation via caspase- and mitochondrial-dependent apoptotic pathways in FaDu human hypopharyngeal squamous carcinoma cells. Therefore, the methanol extract of Ficus carcica leaves provide a natural chemotherapeutic drug for human oral cancer.

• Journal of the Korean housing association
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• v.25 no.6
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• pp.93-100
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• 2014

Community child center is the facility of the highest number of children in child welfare facilities. But plan for the physical environment is not considered importantly because of insufficient finance. However impact of the physical environment in growing children is very closely related in terms of the emotional as well as a functional perspective. Therefore, it is necessary to understand current physical environment and to seek to find alternative methods that can be resolved space matters. As a basic study for this, in the present study we compare and integrate the design principles of child care facility guidelines. And we set up a framework of analysis to derive the design principles that are required in the target area. It is possible to analyze the environmental characteristics of community child center located in Gwang-ju from this framework, to obtain the flowing results. First, draw items are formation of inner direction, provide of environmental supportability, flexibility of use, healthy space. It can be understood that the emotional aspects and physical aspects should be considered comprehensively. Second, as a result of the case analysis, planning elements consideration of the functional aspects appeared high fulfillment rate generally. Planning elements of low fill rate ascertain result from the process take advantage of the narrow space and it was possible to ascertain the study for flexible utilization of space is not. As a result, in order to improve the problems of the target space, increasing the functionality is necessary and also requires consideration of sensitivity of the user's face.

• Natural Product Sciences
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• v.20 no.3
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• pp.216-225
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• 2014

The present study was designed to investigate whether ethylacetate (EtOAc) fraction extracted from Rubus coreanum affect the contractility of the isolated thoracic aortic strips and blood pressure of normotensive rats. The EtOAc fraction ($400{\mu}g/mL$) significantly depressed both phenylephrine (PE, $10{\mu}M$)- and high $K^+$ (56 mM)-induced contractile responses of the isolated thoracic aortic strips in a concentration-dependent fashion. In the simultaneous presence of L-NAME (an inhibitor of NO synthase, $300{\mu}M$) and EtOAc ($400{\mu}g/mL$), both PE- and high $K^+$-induced contractile responses were recovered to the corresponding control level in comparison with inhibition of EtOAc-treatment alone. Moreover, in the simultaneous presence of EtOAc after pretreatment with 0.4% CHAPS, both PE- and high $K^+$-induced contractile responses were recovered to the corresponding control level compared to the inhibitory response of EtOAc-treatment alone. Also, in anesthetized rats, EtOAc fraction (0.3~3.0 mg/kg) injected into a femoral vein dose-dependently produced depressor responses. This hypotensive action of EtOAc fraction was greatly inhibited after treatment with phentolamine (1 mg/kg), chlorisondamine (1 mg/kg), L-NAME (3 mg/kg/30 min) or sodium nitroprusside ($30{\mu}g/kg/30 min$). Intravenous infusion of EtOAc fraction (1.0~10.0 mg/kg/30 min) markedly inhibited norepinehrine-induced pressor responses. Taken together, these results demostrate that EtOAc causes vascular relaxation in the isolated rat thoracic aortic strips as well as hypotensive action in anesthetized rats. These vasorelaxation and hypotension of EtOAc seem to be mediated at least by the increased NO production through the activation of NO synthase of vascular endothelium, and the inhibitory adrenergic modulation.

• International Journal of Oral Biology
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• v.46 no.2
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• pp.85-93
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• 2021

Asarum sieboldii Miq. (Aristolochiaceae) is a perennial herbaceous plant and has been used as traditional medicine for treating diseases, cold, fever, phlegm, allergies, chronic gastritis, and acute toothaches. Also, it has various biological activities, such as antiallergic, antiinflammatory, antinociceptive, and antifungal. However, the anticancer effect of A. sieboldii have been rarely reported, except anticancer effect on lung cancer cell (A549) of water extracts of A. sieboldii. This study investigated the anticancer activity of methanol extracts of A. sieboldii (MeAS) and the underlying mechanism in human FaDu hypopharyngeal squamous carcinoma cells. MeAS inhibited FaDu cells grown dose-dependently without affecting normal cells (L929), as determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and live and dead assay. In addition, concentration of MeAS without cytotoxicity (0.05 and 0.1 mg/mL) inhibited migration and colony formation. Moreover, MeAS treatment significantly induced apoptosis through the proteolytic cleavage of caspase-3, -7, -9, poly (ADP-ribose) polymerase, and downregulation of Bcl-2 and upregulation of Bax in FaDu cells, as determined by fluorescence-activated cell sorting analysis, 4'6-diamidino-2-phenylindole stain, and western blotting. Altogether, these results suggest that MeAS exhibits strong anticancer effects by suppressing the growth of oral cancer cells and the migration and colony formation via caspase- and mitochondrial-dependent apoptotic pathways in human FaDu hypopharyngeal squamous carcinoma cells. Therefore, MeAS can serve as a natural chemotherapeutic for human oral cancer.

• International Journal of Oral Biology
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• v.44 no.3
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• pp.81-88
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• 2019

Trifolium pratense leaves (red clover) has been used in Oriental and European folk medicine for the treatment of whooping cough, asthma, and eczema, and is now being used to treat and alleviate the symptoms, such as hot flushes, cardiovascular health effects that occur in postmenopausal women. However, relatively little scientific data is available on the physiological activity of this plant. Therefore, in this study, we investigated the anti-cancer activity of T. pratense leaves using methanol extract of T. pratense leaves (MeTP) on human FaDu hypopharyngeal squamous carcinoma cells. MeTP inhibited the viability of FaDu cells by inducing apoptosis through the cleavage of procaspase-3, -7, and -9 and poly (adenosine diphosphate ribose-ribose) polymerase (PARP), downregulation of Bcl-2, and upregulation of Bax, as determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, Live & dead assay, 4'6-diamidino-2-phenylindole stain, fluorescence-activated cell sorting analysis, and Western blot analysis. In addition, colony formation was slightly inhibited when FaDu cells were treated with a non-cytotoxic concentration (0.125 mg/mL) of MeTP and almost completely inhibited when cells were treated with 0.25 mg/mL MeTP. Collectively, these results indicate that MeTP induced cell apoptosis via caspase- and mitochondrial-dependent apoptotic pathways, and inhibited colony formation of cancer cells in FaDu human hypopharyngeal squamous carcinoma cells. These findings suggest MeTP should be considered for clinical development as a chemotherapeutic option in oral cancer.

• Journal of the Korea Society of Computer and Information
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• v.19 no.8
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• pp.187-196
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• 2014

This study analyzed whether the factors of studying resilience of high school students had a control effect on self-efficacy and academic achievements depending on the degree of stress. For this purpose, this study set the cause and effect model and the research hypothesis through literature and then conducted a survey of 292 people of high school students in G metropolitan city. The analysis of this study showed that recognition ability and communication skill, which are the factors of studying resilience, had different effects on self-efficacy and academic achievements depending on the degree of stress. It has great significance that if the stress level of the high school students is lower, self-efficacy and academic achievements are higher. Therefore, this study suggested how to inspire the academic achievements based on the results of this analysis.